| Target name | Target organism | UniProt identifier | EC50 | IC50 | Kd | Ki | Source |
|---|
| SARS-CoV-2 | Severe acute respiratory syndrome coronavirus 2 | | | > 20000.0 nM|> 19952.62 nM | | | NPASS |
| Potassium channel subfamily K member 2 | Human | O95069 | | 3.85e+3 nM | | | BindingDB |
| Plasmodium falciparum 3D7 | Plasmodium falciparum 3D7 | | | = 80.0 nM | | | NPASS |
| Plasmodium falciparum (isolate K1 / Thailand) | Plasmodium falciparum K1 | | | = 0.0352 ug.mL-1|= 12.0 nM|= 113.0 nM | | | NPASS |
| Multidrug resistance-associated protein 4 | Homo sapiens | O15439 | | > 133000.0 nM | | | NPASS |
| PC-3 | Homo sapiens | | | > 50000.0 nM | | | NPASS |
| NON-PROTEIN TARGET | | | | = 0.1 ug.mL-1|= 780000.0 nM|= 850000.0 nM | | | NPASS |
| ScN2a | Mus musculus | | | = 10000.0 nM | | | NPASS |
| MES-SA/Dx5 | Homo sapiens | | | = 43000.0 nM|= 67000.0 nM | | | NPASS |
| Plasmodium falciparum | Plasmodium falciparum | | = 110.0 nM | = 370.0 nM|= 120.0 nM|= 0.1596 ug.mL-1|= 0.1499 ug.mL-1|= 0.0996 ug.mL-1|= 0.00908 ug.mL-1|= 380.0 nM|= 0.00361 ug.mL-1|= 0.059 ug.mL-1|= 96.0 nM|= 100.0 nM|= 48.0 nM|= 0.06436 ug.mL-1|= 0.1233 ug.mL-1|= 0.08282 ug.mL-1|= 0.05829 ug.mL-1|= 0.1164 ug.mL-1|= 66.52 nM|= 69.19 nM|= 62.77 nM|= 149.0 nM|= 73.5 nM|= 96.8 nM|= 75.3 nM|= 11.0 nM|= 60.0 nM|= 0.0158 ug.mL-1|= 0.1675 ug.mL-1|= 0.0113 ug.mL-1|= 0.1285 ug.mL-1|= 0.0149 ug.mL-1|= 0.1623 ug.mL-1|= 0.0119 ug.mL-1|= 0.0923 ug.mL-1|= 0.005 ug.mL-1|= 0.036 ug.mL-1|= 0.0194 ug.mL-1|= 0.1144 ug.mL-1|= 269.0 nM|= 413.0 nM|= 0.041 ug.mL-1|= 0.009 ug.mL-1|= 0.0196 ug.mL-1|= 0.102 ug.mL-1|= 200.0 nM|= 0.0176 ug.mL-1|= 0.0148 ug.mL-1|= 0.0349 ug.mL-1|= 0.0157 ug.mL-1|= 0.0388 ug.mL-1|= 0.0111 ug.mL-1|= 0.0546 ug.mL-1|= 220.0 nM|= 0.0686 ug.mL-1|= 0.012 ug.mL-1|= 0.0102 ug.mL-1|= 0.0238 ug.mL-1|= 23.38 nM|= 250.0 nM|= 67.0 ug.mL-1|= 25.0 ug.mL-1|= 0.011 ug.mL-1|= 0.029 ug.mL-1|= 162000.0 nM|= 186000.0 nM|= 456000.0 nM|= 520000.0 nM|= 314.0 nM|= 543.0 nM|= 428.0 nM|= 571.0 nM|= 5.8 nM|= 6.7 nM|= 0.04 ug.mL-1|= 180.0 nM|= 103.8 nM|= 61.8 nM|= 130.3 nM|= 421.7 nM|= 530.9 nM|= 626.6 nM|= 688.7 nM|= 665.3 nM|= 683.9 nM|= 619.4 nM|= 495.5 nM|= 543.3 nM|= 54000.0 nM|= 94.4 nM|= 490.8 nM|= 106.9 nM|= 236.1 nM|= 15.4 nM|= 320.0 nM|= 140.0 nM|= 160.0 nM|= 31.0 nM|= 80.0 nM|= 110.0 nM|= 130.0 nM|= 36.0 nM|= 40.0 nM|= 300.0 nM|= 27.1 nM|= 569.5 nM|= 549.2 nM|= 495.3 nM|= 333.3 nM|= 296.6 nM|= 270.4 nM|= 270.2 nM|= 234.0 nM|= 227.0 nM|= 210.5 nM|= 207.7 nM|= 181.5 nM|= 145.8 nM|= 141.1 nM|= 91.6 nM|= 80.1 nM|= 78.2 nM|= 73.9 nM|= 73.3 nM|= 55.8 nM|= 54.1 nM|= 42.4 nM|= 41.5 nM|= 35.9 nM|= 32.8 nM|= 30.6 nM|= 27.8 nM|= 22.0 nM|= 20.0 nM|= 182.0 nM|= 141.0 nM|= 45.0 nM|= 142.0 nM|= 164.0 nM|= 208.0 nM|= 74.0 nM|= 92.0 nM|= 249.0 nM|= 211.0 nM|= 133.0 nM|= 66.0 nM|= 70.0 nM|= 605.0 nM|= 599.0 nM|= 580.0 nM|= 575.0 nM|= 500.0 nM|= 453.0 nM|= 421.0 nM|= 371.0 nM|= 334.0 nM|= 271.0 nM|= 210.0 nM|= 204.0 nM|= 148.0 nM|= 128.0 nM|= 83.0 nM|= 62.0 nM|= 58.0 nM|= 57.0 nM|= 625.0 nM|= 686.0 nM|= 1034.0 nM|= 1039.0 nM|= 1310.0 nM|= 178.0 nM|= 582.0 nM|= 764.0 nM|= 53.7 nM|= 953.0 nM|= 607.0 nM|= 969.0 nM|= 240.0 nM|= 118.0 nM|= 290.0 nM|= 270.0 nM|= 138.0 nM|= 272.0 nM|= 322.0 nM|= 604.0 nM|= 135.0 nM|= 109.0 nM|= 650.0 nM|= 538.0 nM|= 670.0 nM|= 134.0 nM|= 105.68 nM|= 456.0 nM|= 306.0 nM|= 447.0 nM|= 197.0 nM|= 468.0 nM|= 191.0 nM|= 284.0 nM|= 365.0 nM|= 243.0 nM|= 562.0 nM|= 875.0 nM|= 321.0 nM|= 629.0 nM|= 894.0 nM|= 427.0 nM|= 302.0 nM|= 905.0 nM|= 448.0 nM|= 711.0 nM|= 288.0 nM|= 874.0 nM|= 502.0 nM|= 473.0 nM|= 282.0 nM|= 433.0 nM|= 821.0 nM|= 298.0 nM|= 388.0 nM|= 680.0 nM|= 1016.0 nM|= 218.0 nM|= 870.0 nM|= 886.0 nM|= 1128.0 nM|= 579.0 nM|= 583.0 nM|= 716.0 nM|= 1295.0 nM|= 373.0 nM|= 710.0 nM|= 535.0 nM|= 853.0 nM|= 490.0 nM|= 2123.0 nM|= 514.0 nM|= 475.0 nM|= 513.0 nM|= 574.0 nM|= 1099.0 nM|= 767.0 nM|= 258.0 nM|= 324.0 nM|= 260.0 nM|= 188.0 nM|= 179.0 nM|= 720.0 nM|= 108.0 nM|= 619.0 nM|= 602.0 nM|= 407.0 nM|= 319.0 nM|= 462.0 nM|= 661.0 nM|= 837.0 nM|= 312.0 nM|= 223.0 nM|= 77.13 nM|= 73.96 nM|= 81.0 nM|= 0.268 ug.mL-1|= 0.7 nM|= 18.7 nM|= 29.0 ug.mL-1|= 0.2 ug.mL-1|= 18.67 nM|= 917.0 nM|= 1068.0 nM|= 608.0 nM|= 199.0 nM|= 431.0 nM|= 826.0 nM|= 0.271 ug.mL-1|= 18.0 nM|= 267.92 nM|= 254.0 nM|= 215.0 nM|= 0.026 ug.mL-1|= 286.0 nM|= 504.0 nM|= 161.0 nM|= 473.9 nM|= 830.0 nM|= 0.26 ug.mL-1|= 600.0 nM|= 74.2 nM | | | NPASS |
| Serum albumin | Homo sapiens | P02768 | | | = 309029.54 nM | | NPASS |
| Solute carrier family 22 member 2 | Homo sapiens | O15244 | | | | = 3400.0 nM | NPASS |
| Solute carrier family 22 member 1 | Homo sapiens | O15245 | | = 51600.0 nM | | = 22900.0 nM | NPASS |
| Solute carrier family 22 member 1 | Mus musculus | O08966 | | = 280.0 nM | | | NPASS |
| Solute carrier family 22 member 1 | Rattus norvegicus | Q63089 | | = 900.0 nM|= 1100.0 nM|= 4100.0 nM | | = 930.0 nM|= 4300.0 nM | NPASS |
| Solute carrier family 22 member 2 | Mus musculus | O70577 | | = 2800.0 nM | | | NPASS |
| Solute carrier family 22 member 2 | Rattus norvegicus | Q9R0W2 | | = 13000.0 nM|= 38000.0 nM | | = 55000.0 nM | NPASS |
| Solute carrier organic anion transporter family member 1A1 | Rattus norvegicus | P46720 | | | | = 76700.0 nM | NPASS |
| Solute carrier organic anion transporter family member 1A4 | Rattus norvegicus | O35913 | | | | = 3810.0 nM | NPASS |
| Trypanosoma brucei brucei | Trypanosoma brucei brucei | | | = 6.87 ug.mL-1|= 21200.0 nM | | | NPASS |
| WI-38 | Homo sapiens | | | = 6.56 ug.mL-1 | | | NPASS |
| MES-SA | Homo sapiens | | | = 93000.0 nM|= 91000.0 nM | | | NPASS |
| Sodium channel alpha subunits; brain (Types I, II, III) | Homo sapiens | Q9NY46 | | = 4400.0 nM | | | NPASS |
| Leishmania mexicana mexicana | Leishmamexicana mexicana | | | > 20.0 ug.mL-1 | | | NPASS |
| P-glycoprotein 1 | Homo sapiens | P08183 | | = 430000.0 nM|= 112400.0 nM|= 159300.0 nM|= 167800.0 nM|= 184900.0 nM|= 22600.0 nM|= 74400.0 nM|= 87600.0 nM|= 1700.0 nM | | = 12000.0 nM | NPASS |
| KB | Homo sapiens | | | > 20.0 ug.mL-1 | | | NPASS |
| 5637 | Homo sapiens | | | > 50000.0 nM | | | NPASS |
| Bile salt export pump | Homo sapiens | O95342 | | > 135000.0 nM|= 98830.0 nM|> 133000.0 nM | | | NPASS |
| Canalicular multispecific organic anion transporter 1 | Homo sapiens | Q92887 | | > 133000.0 nM | | | NPASS |
| Canalicular multispecific organic anion transporter 2 | Homo sapiens | O15438 | | > 133000.0 nM | | | NPASS |
| Chikungunya virus | Chikunguvirus | | | = 0.1 ug.mL-1 | | | NPASS |
| Cystic fibrosis transmembrane conductance regulator | Human | P13569 | >50000 nM | | | | BindingDB |
| Cytochrome P450 2D1 | Rattus norvegicus | P10633 | | = 46500.0 nM | | | NPASS |
| Cytochrome P450 2D18 | Rattus norvegicus | Q64680 | | = 1700.0 nM | | | NPASS |
| Cytochrome P450 2D2 | Rattus norvegicus | P10634 | | = 94.0 nM | | | NPASS |
| Cytochrome P450 2D3 | Rattus norvegicus | P12938 | | = 12000.0 nM | | | NPASS |
| Cytochrome P450 2D6 | Homo sapiens | P10635 | | = 610.0 nM|= 1800.0 nM|= 10.0 nM | | = 21000.0 nM|= 4600.0 nM|= 5500.0 nM|= 15000.0 nM | NPASS |
| Leishmania major | Leishmamajor | | = 9410.0 nM|= 9530.0 nM | | | | NPASS |
| Entamoeba histolytica | Eoeba histolytica | | | = 14.8 ug.mL-1 | | | NPASS |
| Jurkat | Homo sapiens | | | > 50000.0 nM | | | NPASS |
| Histidine-rich protein | Plasmodium falciparum | P05227 | | = 7400000000.0 nM | | | NPASS |
| Heme | | | | = 65000.0 nM | | | NPASS |
| HeLa | Homo sapiens | | | > 50000.0 nM | | | NPASS |
| EJ | Homo sapiens | | | > 50000.0 nM | | | NPASS |
| Ferriprotoporphyrin IX | Plasmodium falciparum | | | = 80.0 ug.mL-1|= 250000.0 nM | | | NPASS |
| FM3A | Mus musculus | | = 100000.0 nM | | | | NPASS |
| Escherichia coli | Escherichia coli | | | = 1300000.0 nM | | | NPASS |
| Enterococcus faecium | Enterococcus faecium | | | > 2500000.0 nM | | | NPASS |
| HEK293 | Homo sapiens | | | = 275600.0 nM|= 134350.0 nM | | | NPASS |
