IMPPAT Phytochemical information: 
Spermidine
Spermidine
Bioactivity information
Target nameTarget organismUniProt identifierEC50IC50KdKiSource
Carbonic anhydrase VIHomo sapiensP23280= 1410.0 nMNPASS
Carbonic anhydrase VIIHomo sapiensP43166= 1230.0 nMNPASS
Carbonic anhydrase XIIHomo sapiensO43570= 44100.0 nMNPASS
Carbonic anhydrase XIIIMus musculusQ9D6N1= 11600.0 nMNPASS
Carbonic anhydrase XIVHomo sapiensQ9ULX7= 1000.0 nMNPASS
Coagulation factor XIIIHomo sapiensP00488= 100000.0 nMNPASS
DNA topoisomerase 2-alphaHomo sapiensP11388>1000000 nMBindingDB
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A/1BBos taurusP14100|Q01061>500000 nMBindingDB
Glutamate receptor ionotropic, NMDA 1Rattus norvegicusP35439>10000 nMBindingDB
MDA-MB-231Homo sapiens= 113.0 nMNPASS
L1210Mus musculus> 100000.0 nMNPASS
NON-PROTEIN TARGET> 100000.0 nM|= 3300.0 nM|= 8300.0 nMNPASS
Nucleic Acid= 98000.0 nM|= 105000.0 nM|= 175000.0 nM|= 110000.0 nM|= 300000.0 nMNPASS
Ornithine decarboxylaseBos taurusP271173000000 nM|= 3000000.0 nMBindingDB, NPASS
Ornithine decarboxylaseRattus norvegicusP090572700000 nM|= 2700000.0 nMBindingDB, NPASS
Phosphodiesterase 1Bos taurusP14100> 500000.0 nMNPASS
Pyruvate kinase isozymes M1/M2Homo sapiensP14618= 1410.0 nMNPASS
T47DHomo sapiens= 4400.0 nMNPASS
Carbonic anhydrase VBHomo sapiensQ9Y2D0= 1440.0 nMNPASS
HeLaHomo sapiens= 1500000.0 nM|= 100000.0 nMNPASS
Carbonic anhydrase VAHomo sapiensP35218= 1220.0 nMNPASS
DNA topoisomerase II alphaHomo sapiensP11388> 1000000.0 nMNPASS
Carbonic anhydrase IVHomo sapiensP22748= 112.0 nMNPASS
CHOCricetulus griseus> 100000.0 nMNPASS
CHO-MGCricetulus griseus> 100000.0 nMNPASS
Calf thymus DNABos taurus= 130000.0 nMNPASS
Carbonic anhydrase 1Homo sapiensP009151400 nMBindingDB
Carbonic anhydrase 13Mus musculusQ9D6N111600 nMBindingDB
Carbonic anhydrase 14Homo sapiensQ9ULX71000 nMBindingDB
Carbonic anhydrase 15Mus musculusQ99N2310000 nM|= 10000.0 nMBindingDB, NPASS
Carbonic anhydrase 2Homo sapiensP009181110 nMBindingDB
Carbonic anhydrase 3Homo sapiensP0745111500 nMBindingDB
Carbonic anhydrase 12Homo sapiensO4357044100 nMBindingDB
Carbonic anhydrase 5A, mitochondrialHomo sapiensP352181220 nMBindingDB
Carbonic anhydrase 4Homo sapiensP22748112 nMBindingDB
Carbonic anhydrase IIIHomo sapiensP07451= 11500.0 nMNPASS
Carbonic anhydrase IIHomo sapiensP00918= 1110.0 nMNPASS
Carbonic anhydrase IHomo sapiensP00915= 1400.0 nMNPASS
Carbonic anhydrase 9Homo sapiensQ167901370 nMBindingDB
Carbonic anhydrase IXHomo sapiensQ16790= 1370.0 nMNPASS
Carbonic anhydrase 7Homo sapiensP431661230 nMBindingDB
Carbonic anhydrase 6Homo sapiensP232801410 nMBindingDB
Carbonic anhydrase 5B, mitochondrialHomo sapiensQ9Y2D01440 nMBindingDB