IMPPAT Phytochemical information: 
Spermidine

Spermidine
Clinical trials
Public title (as per ICTRP)Scientific title (as per ICTRP)Trial identifier
The influence of taking the pyrroloquinoline quinone containing food or the spermidine containing food( dried yeast GSP23) in accumulation of the body fat and the muscles in human study.(pilot study)The influence of taking the pyrroloquinoline quinone containing food or the spermidine containing food( dried yeast GSP23) in accumulation of the body fat and the muscles in human study.(pilot study) - The influence of PQQ or the spermidine containing food in accumulation of the body fat and muscles in human study (pilot study)JPRN-UMIN000051636
Bioavailability of Spermidine in Healthy MalesBioavailability of Spermidine in Healthy MalesNCT06017219
Aromatase inhibitor combined with a spermidine-enriched dietary complex supplement for the treatment of spermatogenic failure: a multicenter randomized controlled trialAromatase inhibitor combined with a spermidine-enriched dietary complex supplement for the treatment of spermatogenic failure: a multicenter randomized controlled trialChiCTR2400086133
Characterisation of the postprandial pharmacokinetics of spermidine in humans. Randomised, placebo-controlled, single-centre study in healthy volunteers; two-arm cross-over design with washout phaseCharacterisation of the postprandial pharmacokinetics of spermidine in humans. Randomised, placebo-controlled, single-centre study in healthy volunteers; two-arm cross-over design with washout phaseDRKS00029397
An Exploratory Clinical Study on Autophagy and Multi-level Molecular Profiling During Spermidine SupplementationAutophagy Characterization and Multi-level Molecular Profiling of Spermidine Supplementation: a Clinical StudyNCT04823806
Spermidine Anti-Hypertension StudySpermidine Anti-Hypertension StudyNCT04405388
A single-center, randomized, double-blind, placebo-controlled clinical study: Effects of a spermidine-enriched dietary complex supplement on fertility in subjects with spermatogenesis disordersA single-center, randomized, double-blind, placebo-controlled clinical study: Effects of a spermidine-enriched dietary complex supplement on fertility in subjects with spermatogenesis disordersChiCTR2300077972
Metabolic Responses to Spermidine Supplementation.Randomized, Double-Blind, Crossover Study to Assess the Effects of a Spermidine Supplement on Metabolomics in Older MenNCT05459961
Improving Vaccination in Older Adults by Inducing Autophagy With SpermidineCharacterisation of the Effects of Spermidine, a Nutrition Supplement, on the Immune Memory Response to Coronavirus Vaccine in Older PeopleNCT05421546
This Study Evaluates the Clinical Effect of Adding Spermidine Gel to Minimally Invasive Non-surgical Periodontal Therapy (MINST) to Improve Periodontal Health.Evaluation of Subgingival Mechanical Periodontal Therapy with the Additional Local Application of a Spermidine-Based GelNCT06792916
Investigate the effects of a spermidine supplementation on immune system and inflammatory parameters in old and young adultsInvestigate the effects of a spermidine supplementation on immune system and inflammatory parameters in old and young adults - ImmuneAge-StudyDRKS00025879
Treatment of Peri-implant Mucositis by Application of a Spermidine-based GelTreatment of Peri-implant Mucositis by Non-surgical Debridement and Additional Application of a Spermidine-based GelNCT05926557
Spermidine Intake and All-cause MortalityAssociation Between Dietary Spermidine Intake and Mortality in the Population-based Bruneck StudyNCT03378843
Effects of Spermidine intake on the immune response to Covid-19 vaccineCharacterisation of the effects of Spermidine on the immune response to Covid-19 vaccine in older people - a feasibility study - Spermidine and Covid-19 vaccination in older peopleEUCTR2021-001391-42-AT
Etiology and clinical prevention and treatment of spermatogenesis disordersA randomized controlled clinical study of letrozole combined with spermidine versus letrozole or spermidine alone in the treatment of non-obstructive azoospermiaChiCTR2200058148