IMPPAT | IMPPAT: Indian Medicinal Plants, Phytochemistry And Therapeutics

Bioactivity information

Target name	Target organism	UniProt identifier	EC50	IC50	Ki	Source
Lysosomal alpha-glucosidase	Rattus norvegicus	Q6P7A9		25000 nM\|560000 nM\|400 nM\|360 nM\|1000000 nM\|130 nM		BindingDB
Mannosidase 2, alpha B1	Rattus norvegicus	Q6P762		= 1000000.0 nM		NPASS
Mannosidase 2 alpha 1	Rattus norvegicus	P28494		< 50000.0 nM	< 50000.0 nM	NPASS
MT4	Homo sapiens		> 100000.0 ug.mL-1			NPASS
MS-1	Homo sapiens			= 2000.0 nM		NPASS
MOLT-4	Homo sapiens		> 100000.0 ug.mL-1			NPASS
MCF7	Homo sapiens			> 10000.0 nM		NPASS
Lysosomal alpha-glucosidase	Mus musculus	P70699	98800 nM			BindingDB
LXR-alpha	Homo sapiens	Q13133		> 100000.0 nM		NPASS
Lysosomal alpha-glucosidase	Bos taurus	Q9MYM4		21000 nM\|>300000 nM		BindingDB
Lysosomal acid glucosylceramidase	Homo sapiens	P04062		240000 nM\|118000 nM\|506000 nM\|>300000 nM\|>500000 nM\|195000 nM	79000 nM\|300000 nM\|47000 nM	BindingDB
Lysosomal acid glucosylceramidase	Bos taurus	Q2KHZ8		210000 nM		BindingDB
Lactase/phlorizin hydrolase	Rattus norvegicus	Q02401		34000 nM\|49000 nM\|26000 nM		BindingDB
Lactase/phlorizin hydrolase	Homo sapiens	P09848		62000 nM		BindingDB
Lactase-phlorizin hydrolase	Homo sapiens	P09848		= 62000.0 nM		NPASS
Lactase-glycosylceramidase	Rattus norvegicus	Q02401		= 34000.0 nM\|= 26000.0 nM\|= 49000.0 nM		NPASS
LXR-beta	Homo sapiens	P55055		> 100000.0 nM		NPASS
Lysosomal alpha-glucosidase	Homo sapiens	P10253		410 nM\|1500 nM\|91900 nM\|1000 nM\|60 nM\|= 91900.0 nM\|= 1000.0 nM\|= 60.0 nM\|= 1500.0 nM	3400 nM\|150 nM\|25000 nM\|59 nM\|= 25000.0 nM\|= 150.0 nM\|= 59.0 nM	BindingDB, NPASS
Neutral alpha-glucosidase AB	Homo sapiens	Q14697		25000 nM\|570000 nM\|210000 nM\|500000 nM\|1300 nM\|320000 nM\|= 25000.0 nM\|= 500000.0 nM\|= 570000.0 nM\|= 210000.0 nM\|= 1000000.0 nM\|= 320000.0 nM\|= 1300.0 nM	460000 nM\|21000 nM\|14 nM\|160 nM\|23000 nM\|410000 nM\|= 410000.0 nM\|= 460000.0 nM\|= 23000.0 nM\|= 21000.0 nM\|= 160.0 nM\|= 14.0 nM	BindingDB, NPASS
Neutral alpha-glucosidase C	Mus musculus	Q8BVW0		34000 nM\|= 34000.0 nM\|= 940000.0 nM\|= 300.0 nM		BindingDB, NPASS
Oligo-1,6-glucosidase	Saccharomyces cerevisiae S288c	P53051		= 330000.0 nM		NPASS
Killer cell lectin-like receptor subfamily B member 1A	Rattus norvegicus	P27471		10000 nM		BindingDB
Uncharacterized protein	Sus scrofa	I3LIR5		= 41000.0 nM		NPASS
Trehalose synthase/amylase TreS	Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)	P9WQ18			2.5e+2 nM	BindingDB
Trehalase	Sus scrofa			41000 nM		BindingDB
Trehalase	Rattus norvegicus	O70282		= 42000.0 nM\|= 41000.0 nM		NPASS
Trehalase	Rattus norvegicus			42000 nM\|41000 nM		BindingDB
Trehalase	Homo sapiens	O43280		40000 nM\|= 40000.0 nM		BindingDB, NPASS
Tissue alpha-L-fucosidase	Homo sapiens	P04066		26000 nM	>100000000 nM	BindingDB
Sucrase-isomaltase, intestinal	Rattus norvegicus	P23739		300 nM\|210 nM\|650 nM\|510 nM\|360 nM\|160 nM\|190 nM\|610 nM	24 nM	BindingDB
Sucrase-isomaltase, intestinal	Homo sapiens	P14410		2000 nM		BindingDB
Sucrase-isomaltase	Rattus norvegicus	P23739		= 210.0 nM\|= 300.0 nM\|= 650.0 nM\|= 360.0 nM\|= 160.0 nM\|= 510.0 nM\|= 610.0 nM\|= 190.0 nM	= 24.0 nM	NPASS
Sucrase-isomaltase	Homo sapiens	P14410		= 2000.0 nM		NPASS
SARS-CoV-2	Severe acute respiratory syndrome coronavirus 2			> 20000.0 nM\|> 19952.62 nM		NPASS
Putative alpha-glucosidase	Oryza sativa subsp. japonica			50 nM\|30 nM		BindingDB
Protein-lysine 6-oxidase	Homo sapiens	P28300		1000 nM		BindingDB
Probable maltase-glucoamylase 2	Homo sapiens	Q2M2H8		192000 nM\|39500 nM		BindingDB
Oxysterols receptor LXR-beta	Homo sapiens	P55055		>100000 nM		BindingDB
Oxysterols receptor LXR-alpha	Homo sapiens	Q13133		>100000 nM		BindingDB
Oligo-1,6-glucosidase IMA1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	P53051		330000 nM		BindingDB
Non-lysosomal glucosylceramidase	Homo sapiens	Q9HCG7		20000 nM\|28800 nM\|21000 nM\|30000 nM		BindingDB
HepG2	Homo sapiens			> 10000.0 nM		NPASS
Maltase-glucoamylase	Homo sapiens	O43451		360 nM\|2000 nM\|40 nM\|1400 nM\|8030 nM\|= 360.0 nM\|= 40.0 nM\|= 2000.0 nM\|= 8030.0 nM\|= 1400.0 nM		BindingDB, NPASS
HCT-116	Homo sapiens			> 10000.0 nM		NPASS
Alpha-mannosidase 2C1	Rattus norvegicus	P21139		<50000 nM\|< 50000.0 nM		BindingDB, NPASS
Alpha-mannosidase 2	Rattus norvegicus	P28494		<50000 nM	<50000 nM	BindingDB
Alpha-mannosidase	Rattus norvegicus			1000000 nM		BindingDB
Alpha-mannosidase	Canavalia ensiformis	C0HJB3			270000 nM\|= 270000.0 nM	BindingDB, NPASS
Alpha-glucosidase MAL62	Saccharomyces cerevisiae	P07265		110000 nM\|425600000 nM\|278000 nM\|= 110000.0 nM\|= 278000.0 nM\|= 425600000.0 nM		BindingDB, NPASS
Alpha-glucosidase MAL32	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	P38158		250000 nM		BindingDB
Alpha-glucosidase MAL12	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	P53341		3.95e+4 nM	1.80e+4 nM	BindingDB
Alpha-glucosidase MAL12	Saccharomyces cerevisiae	P53341		2.780e+5 nM		BindingDB
BGC-823	Homo sapiens			> 10000.0 nM		NPASS
Alpha-glucosidase	Saccharomyces cerevisiae S288c	P53341\|P38158\|P07265		= 68800.0 nM\|= 26400.0 nM\|= 39500.0 nM		NPASS
Alpha-glucosidase	Geobacillus stearothermophilus	P94451		= 1670.0 nM		NPASS
Alpha-glucosidase	Bos taurus	Q9MYM4		> 300000.0 nM\|= 21000.0 nM\|= 400.0 nM		NPASS
Alpha-galactosidase A	Homo sapiens	P06280			18000 nM\|= 18000.0 nM	BindingDB, NPASS
Alpha-amylase	Geobacillus stearothermophilus			1670 nM		BindingDB
Alpha-L-fucosidase I	Homo sapiens	P04066		= 26000.0 nM	> 100000000.0 nM	NPASS
Alpha glucosidase	Homo sapiens			= 39500.0 nM\|= 192000.0 nM		NPASS
Acidic alpha-glucosidase	Rattus norvegicus	Q6P7A9		= 560000.0 nM\|= 1000000.0 nM\|= 150000.0 nM\|= 25000.0 nM\|= 360.0 nM\|= 400.0 nM\|= 130.0 nM		NPASS
A549	Homo sapiens			> 1000000.0 nM\|> 10000.0 nM		NPASS
Alpha-glucosidase	Oryza sativa Japonica Group	Q9LGC6		= 30.0 nM\|= 50.0 nM		NPASS
Beta-galactosidase	Bos taurus	Q58D55		300000 nM\|= 300000.0 nM\|> 1000000.0 nM		BindingDB, NPASS
Alpha-galactosidase	Coffea arabica	Q42656		= 23000.0 nM		NPASS
Beta-galactosidase	Rattus norvegicus	D3ZUM4		= 27000.0 nM\|= 30000.0 nM\|= 390000.0 nM\|= 500000.0 nM		NPASS
HCC1937	Homo sapiens			> 10000.0 nM		NPASS
Glycogen debranching enzyme	Oryctolagus cuniculus	P35574		190 nM\|= 190.0 nM		BindingDB, NPASS
Glycogen debranching enzyme	Homo sapiens	P35573		10000 nM\|= 10000.0 nM		BindingDB, NPASS
Glucosylceramidase	Bos taurus	Q2KHZ8		= 210000.0 nM		NPASS
Early activation antigen CD69	Homo sapiens	Q07108		630957 nM		BindingDB
Cytosolic beta-glucosidase	Homo sapiens	Q9H227		80000 nM\|240000 nM		BindingDB
Cholinesterase	Equus caballus	P81908		= 10000.0 nM		NPASS
Beta-mannosidase	Bacteroides thetaiotaomicron				14000000 nM	BindingDB
Ceramide glucosyltransferase	Homo sapiens	Q16739		>100000 nM\|> 100000.0 nM		BindingDB, NPASS
Beta-glucosidase A	Caldicellulosiruptor saccharolyticus	P10482		460000 nM\|100000 nM\|55000 nM\|= 460000.0 nM\|= 520000.0 nM\|= 55000.0 nM\|= 100000.0 nM		BindingDB, NPASS
Beta-glucosidase	Rhizobium radiobacter	P27034			12000 nM	BindingDB
Beta-glucosidase	Prunus avium	Q43014		= 81000.0 nM	= 9500.0 nM	NPASS
Beta-glucosidase	Prunus avium			81000 nM	9500 nM	BindingDB
Beta-glucosidase	Homo sapiens	Q9HCG7		= 20000.0 nM\|= 28800.0 nM\|= 21000.0 nM\|= 30000.0 nM		NPASS
Beta-glucosidase	Agrobacterium tumefaciens	P27034			= 12000.0 nM	NPASS
HUVEC	Homo sapiens			= 2000.0 nM		NPASS
Beta-glucocerebrosidase	Homo sapiens	P04062		= 118000.0 nM\|> 300000.0 nM\|> 500000.0 nM\|= 240000.0 nM\|= 506000.0 nM\|= 195000.0 nM	= 2000.0 nM\|= 300000.0 nM\|= 47000.0 nM\|= 79000.0 nM	NPASS
Beta-glucosidase cytosolic	Homo sapiens	Q9H227		= 240000.0 nM\|= 80000.0 nM		NPASS
Beta-galactosidase	Rattus norvegicus			27000 nM\|500000 nM\|390000 nM\|30000 nM		BindingDB

a curated database

IMPPAT Phytochemical information:
1-Deoxynojirimycin

Bioactivity information

IMPPAT Phytochemical information: 1-Deoxynojirimycin

Bioactivity information

IMPPAT Phytochemical information:
1-Deoxynojirimycin