IMPPAT Phytochemical information: 
Zardaverine
Zardaverine
Bioactivity information
Target nameTarget organismUniProt identifierEC50IC50KdKiSource
cAMP-specific 3',5'-cyclic phosphodiesterase 4D [372-376,381-715,S375G,I381V,S383G,G384S,V385H,K386M)Homo sapiensQ08499390 nMBindingDB
cGMP-specific 3',5'-cyclic phosphodiesterase [531-875]Homo sapiensO7607481000 nMBindingDB
cGMP-specific 3',5'-cyclic phosphodiesteraseHomo sapiensO76074>10000 nMBindingDB
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B [650-1084]Homo sapiensQ133701500 nMBindingDB
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3BHomo sapiensQ13370|Q14432110 nM|631 nMBindingDB
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3AHomo sapiensQ144325e+2 nMBindingDB
cGMP-dependent 3',5'-cyclic phosphodiesterase [574-941]Homo sapiensO00408>200000 nMBindingDB
cGMP-dependent 3',5'-cyclic phosphodiesteraseRattus norvegicusQ01062>10000 nMBindingDB
cAMP-specific 3',5'-cyclic phosphodiesterase 7B [91-450]Homo sapiensQ9NP56>200000 nMBindingDB
cAMP-specific 3',5'-cyclic phosphodiesterase 4DHomo sapiensQ084995e+2 nM|390 nM|800 nM|2000 nM|160 nMBindingDB
PhosphodiesteraseTrypanosoma cruzi>1.00e+5 nMBindingDB
cAMP-specific 3',5'-cyclic phosphodiesterase 4BHomo sapiensQ073431410 nMBindingDB
cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4DRattus norvegicusP14270|P14644|P14646|P54748210 nMBindingDB
cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4DHomo sapiensP27815|Q07343|Q08493|Q08499158 nM|800 nM|1100 nMBindingDB
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A [432-779]Homo sapiensQ9Y23314000 nMBindingDB
Isoform 4 of Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A (PDE11A1) 35-489]Homo sapiensQ9HCR9140000 nMBindingDB
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A [226-593]Homo sapiensO76083>200000 nMBindingDB
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8AHomo sapiensO60658160000 nMBindingDB
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1BHomo sapiensQ01064>200000 nMBindingDB
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A/1BBos taurusP14100|Q01061>10000 nMBindingDB
cAMP-specific 3',5'-cyclic phosphodiesterase 4B [316-320,321-700,S319G,N320S,N321H,T322M]Homo sapiensQ07343930 nMBindingDB