IMPPAT Phytochemical information: 
1,3,5,8-Tetrahydroxyxanthone
1,3,5,8-Tetrahydroxyxanthone
Bioactivity information
Target nameTarget organismUniProt identifierEC50IC50KdKiSource
Dual specificity tyrosine-phosphorylation-regulated kinase 4Homo sapiensQ9NR20> 10000.0 nMNPASS
Monoamine oxidase AHomo sapiensP21397= 13000.0 nMNPASS
Maltase-glucoamylaseHomo sapiensO43451= 5300.0 nM|= 5200.0 nMNPASS
HT-22Mus musculus= 2500.0 nMNPASS
Glycogen synthase kinase-3 betaHomo sapiensP49841> 10000.0 nM> 10000.0 nMNPASS
Dual-specificity tyrosine-phosphorylation regulated kinase 3Homo sapiensO43781> 10000.0 nMNPASS
Dual-specificity tyrosine-phosphorylation regulated kinase 2Homo sapiensQ92630= 2713.0 nMNPASS
U-251Homo sapiens> 100000.0 nMNPASS
Dual-specificity tyrosine-phosphorylation regulated kinase 1AHomo sapiensQ13627= 266.1 nM= 60.02 nMNPASS
Dual specificity tyrosine-phosphorylation-regulated kinase 1BHomo sapiensQ9Y463= 268.3 nMNPASS
Cyclin-dependent kinase 5/CDK5 activator 1Homo sapiensQ15078= 200.0 nMNPASS
Dual specificity protein kinase CLK3Homo sapiensP49761= 7530.0 nMNPASS
Dual specificity protein kinase CLK2Homo sapiensP49760= 1697.0 nMNPASS
Dual specificity protein kinase CLK1Homo sapiensP49759= 238.8 nM= 29.74 nMNPASS
Cyclin-dependent kinase 5/CDK5 activator 1Homo sapiensQ00535|Q15078> 10000.0 nMNPASS
Cyclin-dependent kinase 5 activator 1Homo sapiensQ00535|Q15078200 nMBindingDB
Cyclin-dependent kinase 5Homo sapiensQ005352e+2 nM2.0e+2 nM|1.4e+2 nMBindingDB
Casein kinase I epsilonHomo sapiensP49674> 10000.0 nMNPASS
C6Rattus norvegicus> 100000.0 nMNPASS
Amine oxidase [flavin-containing] AHomo sapiensP2139713000 nMBindingDB
Dual specificity protein kinase CLK4Homo sapiensQ9HAZ1= 146.3 nMNPASS