IMPPAT Phytochemical information: 
Choline

Choline
Clinical trials
Public title (as per ICTRP)Scientific title (as per ICTRP)Trial identifier
Comparative study of Panchavalkal Kashay with Madhu Kawal and Choline salicylate gel in MukhapakaRandomized controlled clinical trial to study the efficacy of Panchavalkal Kashay with Madhu Kawal and Choline salicylate gel in MukhapakaCTRI/2019/06/019719
Choline Dehydrogenase and Sperm Function: Effects of BetaineCholine Dehydrogenase and Sperm Function: Effects of BetaineNCT02122211
Dietary Supplementation to Increase Serum Choline LevelsDietary Supplementation to Increase Serum Choline LevelsNCT02403804
Silymarin-Choline Combination Versus Ursodeoxycholic Acid in Non-Alcoholic Fatty Liver DiseaseSilymarin-Choline Combination Versus Ursodeoxycholic Acid in Non-Alcoholic Fatty Liver Disease: A Randomised Double-Blind Clinical TrialCTRI/2019/04/018550
ETUDE MULTICENTRIQUE, RANDOMISEE EN DOUBLE AVEUGLE VERSUS PLACEBO EVALUANT L’EFFICACITE D’UN TRAITEMENT ADDITIONNEL PAR CHOLECALCIFEROL (VITAMINE D3) CHEZ DES PATIENTS ATTEINTS DE SCLEROSE EN PLAQUES RECURRENTE (SEP-R) TRAITES PAR INTERFERON BETA 1A 44 µG 3 FOIS PAR SEMAINE PAR VOIE SOUS-CUTANEE - cholineETUDE MULTICENTRIQUE, RANDOMISEE EN DOUBLE AVEUGLE VERSUS PLACEBO EVALUANT L’EFFICACITE D’UN TRAITEMENT ADDITIONNEL PAR CHOLECALCIFEROL (VITAMINE D3) CHEZ DES PATIENTS ATTEINTS DE SCLEROSE EN PLAQUES RECURRENTE (SEP-R) TRAITES PAR INTERFERON BETA 1A 44 µG 3 FOIS PAR SEMAINE PAR VOIE SOUS-CUTANEE - cholineEUCTR2009-013695-46-FR
Impact Of Choline in Patients With NAFLDThe Impact Of Choline Administration On Oxidative Stress And Clinical Outcome Of Patients With Non-Alcoholic Fatty Liver Disease NAFLDNCT05200156
Effects of Berberine on Intestinal Microflora, Metabolites and Cardiovascular Function in People After High Choline DietEffects of Berberine on Intestinal Microflora, Metabolites and Cardiovascular Function in People After High Choline DietChiCTR2100046956
Low-Dose Selinexor and Choline Salicylate for Non-Hodgkin or Hodgkin Lymphoma, Histiocytic/Dendritic Cell Neoplasm, or Relapsed or Refractory Multiple MyelomaPhase Ib Trial of Low-Dose Selinexor (KPT-330) in Combination with Choline Salicylate (CS) for the Treatment of Patients with Non-Hodgkin Lymphoma (NHL), Hodgkin Lymphoma, Histiocytic/Dendritic Cell Neoplasms, or Multiple MyelomaNCT04640779
Inuline Supplement in Patients With Irritable Bowel SyndromeClinical Assessment of the Benefits of the Combination Inuline, Choline and Silymarin in Mitigating the Symptomatology in Patients With Irritable Bowel SyndromeNCT03174561
Serum choline with linear growth failure in young children from rural MalawiSerum choline with linear growth failure in young children from rural MalawiISRCTN14597012
Efficacy and Safety of CDP-choline in Patients With Methamphetamine DependenceNCT01007539
Confirming the pharmacological interaction between colchicine and 18F-choline PETConfirming the pharmacological interaction between colchicine and 18F-choline PET - Interaction between colchicine and choline PETNL-OMON38465
Efficacy and Tolerance of Treatment With DHA, Choline and Vitamin E in Children With Non-alcoholic SteatohepatitisStudy of Efficacy and Tolerance of Treatment With DHA, Choline and Vitamin E in Children With Non-alcoholic SteatohepatitisNCT01934777
Use of Galantamine and CDP-choline (Citicoline) to Treat Adults With SchizophreniaInterventions to Test the Alpha7 Nicotinic Receptor Model in SchizophreniaNCT00509067
Using magnetic resonance spectroscopy (MRS) to identify breast cancer patients who early respond to chemotherapy (after the first chemotherapy cycle) before breast cancer surgery.Phase II study on prospective evaluating the quantification of total choline by magnetic resonance spectroscopy (MRS) in breast tumours as an early predictive marker of neoadjuvant chemotherapy response in early breast cancer patients - CholineEUCTR2011-006259-12-BE
Choline and bone healthCholine supplementation in postmenopausal women: effects on bone health and risk markers for cardiovascular disease (CVD) - a randomised double-blind placebo-controlled intervention trialISRCTN82708510
Effect of Betaine and Choline on Metabolic HealthABC (Additional Betaine and Choline) Study: Effect of Betaine and Choline Intake on Biomarkers of Metabolic Health in HumansNCT06758856
Effect of treatment of the cholinergic precursor Choline Alfoscerate in mild cognitive dysfunctionEffect of treatment of the cholinergic precursor Choline Alfoscerate in mild cognitive dysfunctionCTIS2025-520685-21-00
A Preliminary Study of Choline and Betaine Supplementation Among Adults Exposed to Arsenic in BangladeshA Pilot Study of Choline and Betaine Supplementation in Arsenic-exposed Individuals in BangladeshNCT01749982
Effect of methyl donor supplementation in treatment of overweight and obesityProcessing and production of a methyl donor supplement (choline,folic acid, cobalamine, pyrodoxine and riboflavin) and the assessment of its effects on the anthropometric measurements, glycemic indices, lipid profile, appetite regulating hormones and the level of gene expression of leptin in overweight and obese subjectsIRCT20180528039881N1
Choline Supplementation in Children With Fetal Alcohol Spectrum DisordersCholine Supplementation in Children With Fetal Alcohol Spectrum DisordersNCT01911299
First-in-human Testing of a Multi-Analyte Sensor Platform for Glucose/Lactate/Oxygen/Choline in People with DiabetesAccuracy and Feasibility of a Novel Glucose/Lactate/Oxygen/Choline Multi-Analyte Sensing Platform in HumansACTRN12623000537651