IMPPAT Phytochemical information: 
Betaine

Betaine
Clinical trials
Public title (as per ICTRP)Scientific title (as per ICTRP)Trial identifier
Effect of betaine (trimethyl glycine) from sugar beet on metabolic syndromeEffect of betaine (trimethyl glycine) from sugar beet on metabolic syndrome - Effect of betaine from sugar beet on metabolic syndromeJPRN-UMIN000037404
Maternal Betaine Supplementation During BreastfeedingMaternal Betaine Supplementation During BreastfeedingNCT04633044
Betaine Effect in Speed-strength AthletesThe Effect of Betaine Supplementation on Body Composition and Physical Capacity of Speed-strength Male AthletesNCT03702205
A clinical trial of betaine in schizophreniaAn exploratory trial of betaine supplementation in patients with schizophrenia - An exploratory trial of betaine supplementation in patients with schizophreniaJPRN-jRCTs031180371
Effect of Betaine and Food on Gastric pHCountering the Gastric ph Effect of a Standardized Meal in Healthy Volunteers Using Clinical Doses of Betaine HydrochlorideNCT02758015
A Prospective, Randomized, Open Label Trial of Two Doses of Oral BetaineA Prospective, Randomized, Open Label Trial of Two Doses of Oral Betaine in Patients With Non-alcoholic Fatty Liver Disease (NAFLD) and Elevated Alanine Aminotransferase (ALT)NCT03073343
Effects of betaine (trimethyl glycine) from sugar beet on hepatic functionEffects of betaine (trimethyl glycine) from sugar beet on hepatic function - Effects of betaine from sugar beet on hepatic functionJPRN-UMIN000037405
Effect on Cytokines IL-1ß, TNF-a, IL-4, and Total Bacterial Load of a Composition Comprising Olive Oil, Trimethylglycine and Xylitol Delivered as a ToothpasteEffect on Cytokines IL-1ß, TNF-a, IL-4 and Total Bacterial Load of an Oral Topical Composition Comprising Olive Oil, Trymethylglycine and Xylitol: a Randomized Controlled Double-blind Clinical Trial Part of the Stop Dysbiosis Project (SDP)NCT06786910
Effect of Betaine and Choline on Metabolic HealthABC (Additional Betaine and Choline) Study: Effect of Betaine and Choline Intake on Biomarkers of Metabolic Health in HumansNCT06758856
Potential Synergistic Effect of Combined Blood Flow Restriction Training and Betaine Supplementation on Skeletal MuscleThe Potential Synergistic Effect of Combined Blood Flow Restriction Training and Betaine Supplementation on Skeletal Muscle Mechanotransduction-Associated Cell SignalingNCT05790070
The Effects of Pre-Loaded Betaine Supplementation on Thermoregulation and Exercise Metabolism in the HeatThe Effects of Pre-Loaded Betaine Supplementation on Thermoregulation and Exercise Metabolism in the HeatNCT04585295
An exploratory trial of betaine supplementation in patients with schizophreniaAn exploratory trial of betaine supplementation in patients with schizophrenia - An exploratory trial of betaine supplementation in patients with schizophreniaJPRN-UMIN000017295
Exploratory Study on the Efficacy of Betaine Hydrochloride in Treating Autoimmune GastritisExploratory Study on the Efficacy of Betaine Hydrochloride in Treating Autoimmune GastritisNCT06881511
The Therapeutic Effect of Betaine in SyringomyeliaThe Effect of Betaine in Refractory Syringomyelia(RS)NCT06308367
Betaine METABOLISM OF PATIENTS With HomocystinuriaBetaine METABOLISM OF PATIENTS With HomocystinuriaNCT02404337
Firefighter Thermoregulatory Responses in Active Fire with Betaine SupplementationThermoregulatory Responses of Betaine Supplementation in Firefighters During Live BurnNCT06042270
Non profit study of phase II randomized, double blind, placebo controlled, parallel groups, dose-finding trial with 3 different doses of Betaine versus placebo in subjects affected by PAD (Peripheral Arterial Occlusive Disease)? - VAS07BENon profit study of phase II randomized, double blind, placebo controlled, parallel groups, dose-finding trial with 3 different doses of Betaine versus placebo in subjects affected by PAD (Peripheral Arterial Occlusive Disease)? - VAS07BEEUCTR2008-004641-29-IT
Betaine Supplementation and Lipid Metabolism in Overweight and Obese Pre-menopausal WomenThe Impact of Betaine Supplementation on Body Composition and Lipid Metabolism in a Group of Overweight and Obese WomenNCT06344377
Pilot Comparison of Standard Antiviral Therapy With and Without 12 Weeks of Betaine in Genotype 1 Naive PatientsComparison of Standard Therapy,Peginterferon Alpha-2a + Ribavirin for 48 Weeks VS Peginterferon Alph-2a + Ribavirin + Betaine for 12 Weeks Followed by 36 Weeks Standard Therapy in Untreated Adults With Chronic Hepatitis C Genotype 1NCT00571714
Betaine, Exercise Performance, and Gut PermeabilityInfluence of 2-Weeks DuraBeet® Ingestion on Cycling Performance, Gut Permeability, and Metabolite ShiftsNCT06392360
The influence of proline betaine in orange juice on homocysteine concentrations in healthy male CaucasiansA study to compare orange juice versus supplementation with proline betaine on homocysteine concentrations in healthy male CaucasiansACTRN12606000501549
Effects of Betaine Supplementation on Strength and Muscle Creatine ContentEffects of Betaine Supplementation Combined or Not With Creatine Supplementation on Muscle Creatine Content and StrengthNCT01213719
Chronic Hepatitis C Non-Responder Study With AdoMet and BetaineChronic Hepatitis C: Treatment of (Peg)Interferon Alpha - Ribavirin Non-Responders With Pegylated Interferon alpha2b, Ribavirin, AdoMet and BetaineNCT00310336
Efficacy of Betaine for Reduction of Urine Oxalate in Patients With Type 1 Primary HyperoxaluriaEfficacy of Betaine for Reduction of Urine Oxalate in Patients With Type 1 Primary HyperoxaluriaNCT00283387
The effect of Glycine Betaine on fasting and Post methionine load homocysteine concentrations in healthy volunteers.The effect of Glycine Betaine on fasting and Post methionine load homocysteine concentrations in healthy volunteers.ACTRN12605000434695
Natural Supplements for Unipolar DepressionPhase 4 Study: An Open Study of the Efficacy and Tolerability in Unipolar Depression of Augmentation of the One-carbon Cycle With L-methionine, Betaine and FolateNCT00226356
Effect of Betaine, Serine and Folic Acid on Vascular Function in Healthy VolunteersEffect of Lowering of Plasma Homocysteine Concentrations After an Oral Methionine Load on Vascular Function in Healthy VolunteersNCT00126347
The long-term effects of Betaine supplementation on Cholesterol, Blood Sugar levels, Body Measurements, Cardiovas-cular Health, and Exercise Habits in adults who engage in WeightliftingChronic effects of Betaine supplementation on Lipid and Glycemic profile, Anthropometric and Cardiovascular parame-ters, and on Physical Exercise practice in adults engaged in Weightlifting: a randomized, double-blind, placebo-contro-lled study -RBR-2bd7gnb
Effect of Betaine and Folic Acid on Vascular Function in Healthy HumansEffect of Lowering of Fasting Plasma Homocysteine Concentrations Through Supplementation With Betaine or Folic Acid on Vascular Function in Healthy VolunteersNCT00102843
Chronic dietary modification versus supplementation with glycine betaine, on fasting and post-methionine load homocysteine concentrations in healthy volunteers.A study to compare dietary modification versus supplementation with glycine betaine, on fasting and post-methionine load homocysteine concentrations in healthy volunteers.ACTRN12606000104550
Study of the Ability of Betaine Hydrochloride to Increase Stomach Acid in Healthy VolunteersPilot Study Evaluating Gastric Re-acidification Using Betaine Hydrochloride in Healthy Volunteers With Pharmacologically Induced HypochlorhydriaNCT01237353
Pilot Study of Betaine + Combination Antiviral Therapy for Chronic Hepatitis C Genotype 1 Non-responder/RelapsersPilot Therapy Using Betaine in Combination With Peginterferon Alpha-2a Plus Ribavirin in Subjects With Genotype 1 Hepatitis C Who Have Not Achieved a Sustained Viral Response With a Prior Course of Pegylated Interferon and RibavirinNCT00882193
A Preliminary Study of Choline and Betaine Supplementation Among Adults Exposed to Arsenic in BangladeshA Pilot Study of Choline and Betaine Supplementation in Arsenic-exposed Individuals in BangladeshNCT01749982
Chitosan-based magnetic nanoparticles for facial pimplesInvestigating the Effect of Use of Cobalt Ferrite -Conjugated Chitosan-Betaine Facial Masks in improvement and acceleration of treatment in patients with Acne VulgarisIRCT20221113056487N2
Choline Dehydrogenase and Sperm Function: Effects of BetaineCholine Dehydrogenase and Sperm Function: Effects of BetaineNCT02122211
Betain and haemophilia ABetHäm2012: A monocenter, single-blind, randomized, 2-armed, placebo-controlled, cross-over study to investigate coagulation markers in patients with haemophilia A after administration of BetainEUCTR2012-001039-30-DE
Modulation of Insulin Sensitivity by Betaine Upregulation of FGF21Modulation of Insulin Sensitivity by Betaine Upregulation of FGF21NCT02118142
Effect of Betaine Supplementation on Body Composition in Metabolic SyndromeA randomised controlled trial evaluating the effects of Betaine Supplementation on Body Composition in Adult Males with Metabolic SyndromeACTRN12614000232639
Effect of betaine supplementation on the athlete's ability to perform multiple repetitions on the bench pressEffect of betaine supplementation on athletes' physical capacityRBR-7k79kd
Betaine and Peroxisome Biogenesis DisordersA Pilot, Open Label Trial Assessing the Safety and Efficacy of Betaine in Children With Peroxisome Biogenesis Disorders.NCT01838941
Metabolic Effects of Betaine SupplementationBedside to Bench and Back: Cardiometabolic Effects of Betaine SupplementationNCT01950039