IMPPAT Phytochemical information: 
(-)-Epicatechin

(-)-Epicatechin
Clinical trials
Public title (as per ICTRP)Scientific title (as per ICTRP)Trial identifier
Epicatechin - a phytochemical for cardiovascular protection?Epicatechin - a phytochemical for cardiovascular protection? - EpiProtectDRKS00009846
(+) Epicatechin to Treat Friedreich's AtaxiaA Phase II, Open Label Prospective Single Center Drug Study Evaluating the Safety and Efficacy of (+)-Epicatechin in Subjects With Friedreich's AtaxiaNCT02660112
Effects of Epicatechin-rich Cocoa on Collagen SynthesisDetermining an Optimal Dose of Epicatechin-Rich Chocolate and Its Effect on PerformanceNCT03214133
Plus Epicatechin Duchenne Muscular Dystrophy in Non-ambulatory AdolescentsA Single Center Dose Ranging Pilot Study of (+)-Epicatechin in Non-ambulatory Adolescents With Duchenne Muscular Dystrophy and Pre-symptomatic Cardiac DysfunctionNCT02964377
Safety and Biomarker Response to (+)-Epicatechin in Becker Muscular DystrophyA Phase 1, Open-label, Dose Escalation Study to Evaluate the Safety and Preliminary Efficacy of Orally Administered (+)-Epicatechin in Patients With Becker or Becker-like Muscular Dystrophy With Continued Ambulation Past 16 Years of AgeNCT04386304
The Effect of the Nutraceutical (-)- Epicatechin on Myosteatosis in Patients with Advanced CKDThe Effect of the Nutraceutical (-)- Epicatechin on Myosteatosis in Patients with Advanced CKD: a Pilot Study (EPIC-CKD)NCT06631820
Early Phase Pre-Clinical and Initial Clinical Research on Epicatechin (Part 2)Early Phase Pre-Clinical and Initial Clinical Research on Epicatechin (Part 2)NCT02656212
Effect of resistance training and Epicatechin on SarcopeniaImprovement of muscle strength and circulatory levels of plasma Follistatin and Myostatin following resistance training and Epicatechin supplementation in sarcopenic older adultsIRCT2017101423002N4
Effects of Epicatechin on Statins for Mitochondrial Dysfunction and Impaired Exercise CapacityEffects of Epicatechin on Patients With Statin-induced Mitochondrial Dysfunction and Impaired Exercise CapacityNCT02490527
(-)- Epicatechin Becker Muscular DystrophyUCD0115B: An Open-label Extension Study of Purified Epicatechin to Improve Mitochondrial Function, Strength and Skeletal Muscle Exercise Response in Becker Muscular DystrophyNCT03236662
An Investigation of the Dose-dependent Vascualr Effects of (-)-Epicatechin in Healthy MenAn Acute, Double-blind, Randomised, Placebo-controlled, Crossover Intervention Trial Investigating the Dose-dependent Vascular Effects of Pure (-)-Epicatechin (=1 mg/kg BW) in Healthy Men.NCT02292342
Comparison of Pure Epicatechin and Cocoa on Markers of Vascular FunctionComparison of Pure Epicatechin and Cocoa on Markers of Vascular FunctionNCT02221791
Comparison of Pure Epicatechin and Cocoa on Markers of Vascular FunctionComparison of Pure Epicatechin and Cocoa on Markers of Vascular Function - Comparison of Epicatechin and CocoaNL-OMON41113
Absorption, Metabolism, and Excretion of (-)-[2-14C]Epicatechin in HumansA Single-Center, Open-Label Study to Evaluate the Absorption, Metabolism, and Excretion of (-)-[2-14C]Epicatechin Following Oral IntakeNCT01969994
(-)-Epicatechin and Pulmonary Arterial HypertensionAn Open Label Pilot Study of Purified (-)-Epicatechin to Improve Hemodynamics in Pulmonary Arterial HypertensionNCT01880866
Use of (-)-Epicatechin in the Treatment of Becker Muscular Dystrophy (Pilot Study)An Open-label Pilot Study of Purified Tea-derived Epicatechin to Improve Mitochondrial Function, Strength and Skeletal Muscle Exercise Response in Becker Muscular Dystrophy.NCT01856868
Effect of an Apple Polyphenol Extract on Brachial Artery Flow-mediated Vasodilatory FunctionThe Effect of an Apple Polyphenol Extract Rich in Epicatechin and Flavan-3-ol Oligomers (Evesseā„¢ EPC) on Brachial Artery Flow-mediated Vasodilatory Function (FMD)in Volunteer SubjectsNCT01690676
Study on the Effects of Epicatechin and Quercetin Supplementation on Vascular Function and Blood Pressure (FLAVO)Study on the Effects of Epicatechin and Quercetin Supplementation on Vascular Function and Blood Pressure in Untreated (Pre)Hypertensive SubjectsNCT01691404
Early Phase Pre-Clinical and Initial Clinical Research on Epicatechin(+)-Epicatechin: Early Phase Pre-Clinical and Initial Clinical Research on EpicatechinNCT02330276
Relevance of Vascular Function Markers: Study on the Effects of Quercetin and Epicatechin on Blood Pressure and Vascular Function in (Pre)Hypertensive SubjectsRelevance of Vascular Function Markers: Study on the Effects of Quercetin and Epicatechin on Blood Pressure and Vascular Function in (Pre)Hypertensive Subjects - The FLAVO-studieNL-OMON39481
Effects of Dark Chocolate on Exercise Capacity, and Mitochondrial Structure and FunctionEffects of Epicatechin-enriched Dark Chocolate on Mitochondrial Function and Exercise Capacity in Patients With Both Diabetes and Heart Failure and in Sedentary IndividualsNCT01671514
Influence of Piperine on the bioavailability of epicatechin and epigallocatechin - a pilot studyInfluence of Piperine on the bioavailability of epicatechin and epigallocatechin - a pilot study - E-Pip-PilotDRKS00020741