IMPPAT Phytochemical information: 
gamma-Aminobutyric acid

gamma-Aminobutyric acid
Clinical trials
Public title (as per ICTRP)Scientific title (as per ICTRP)Trial identifier
The study of relaxing and sleep effects from intake of test food containing gamma-Aminobutyric acidThe study of relaxing and sleep effects from intake of test food containing gamma-Aminobutyric acid - The study of relaxing and sleep effects from intake of test food containing gamma-Aminobutyric acidJPRN-UMIN000045759
Evaluation of Safety and Diabetes Status Upon Oral Treatment With GABA in Patients With Longstanding Type-1 DiabetesA Phase I/II, 3-Arm, Open Label, Single Centre Study to Investigate the Safety and Effect of Oral GABA Therapy on Beta-Cell Regeneration in Type 1-diabetes PatientsNCT03635437
Intervention With a GABA Supplement in PrediabeticsThe Effects of a GABA Supplement Versus a Placebo on Glucose Tolerance and Blood Pressure in PrediabeticsNL-OMON20448
Open label pilot trial to evaluate safety and diabetes status upon oral treatment with GABA in patients with longstanding type-1 diabetes.A Phase I/II, 2-Arm, Open Label, Single Centre Study to Investigate the Safety and Effect of Oral GABA Therapy on ß-cell Regeneration in Type 1-diabetes PatientsEUCTR2018-001115-73-SE
Plasmakinetics of gamma-aminobutyric acid from tomatoes as compared to a supplement, after a single oral administration in healthy young menPlasmakinetics of gamma-aminobutyric acid from tomatoes as compared to a supplement, after a single oral administration in healthy young men - Relative oral bio-availability of GABA from tomatoesNL-OMON48303
Intervention With a GABA Supplement in PrediabeticsThe Effects of a GABA Supplement Versus a Placebo on Glucose Tolerance and Blood Pressure in PrediabeticsNCT04303468
effects of use of pre operattive l theanine and gabaCOMPARISON OF THE EFFECTS OF TWO AMINO ACIDS: GAMMA-AMINOBUTYRIC ACID AND L-THEANINE ON SEDATION, ANXIETY AND COGNITION IN PRE-OPERATIVE SURGICAL PATIENTS-A RANDOMISED CONTROLLED TRIAL - CTGLSACCTRI/2021/08/035694
GABA and Beta-cell RegenerationGABA From Medical Nutrition to Pancreatic Beta-cell RegenerationNCT04375020
Effect of GABA on ADHD and Seizures in Children With Epilepsy.Effect of Gamma Aminobutyric Acid on ADHD and Seizures in Children With Epilepsy.NCT04144439
Evaluation of Aminobutyric Acid, Glutamic Acid, Calcium, Thiamine, Pyridoxine and Cyanocobalamin as Therapy for VertigoDouble Blind Evaluation of Gamma-aminobutyric Acid Tartarate 100 mg, Glutamic Acid 100 mg, Dibasic Calcium Phosphate 50 mg, Thiamine Nitrate 25 mg, Pyridoxine Chloride 10 mg and Cyanocobalamin 5 mcg Versus Ginger for Vertigo-kinetosisNCT05221892
Effects of Gamma Aminobutyric Acid associated with Physical Exercise in Sedentary womenGABA Phytotherapeutic for Strength Exercise practitioners - GABA - Gamma-Aminobutyric AcidRBR-8t7h259
Effects of Supplementation with Acid Gamma-aminobutyric associated with physical exercises at home for elderlyEffects of Gamma-aminobutyric acid Supplementation combined with Physical exercises at Home on skeletal muscle mass in the elderlyRBR-5ftj2fy
Clinical Study to Investigate the Sleep Quality Enhancing Effect of GABAA Randomized, Double-blind, Placebo-controlled, Parallel Clinical Study to Investigate the Sleep Quality Enhancing Effect and Safety of Lactobacillus-fermented GABA in Subjects With Mild, Transient Sleep DisorderNCT04857021
The beneficial effect on cardiovascular function of a food supplement based on red yeast rice (monacolin K), gamma-oryzanol from rice bran, and gamma-aminobutyric acid.Study of the efficacy of supplementation with a mixture of red fermented rice (monacolin K), gamma-oryzanol from rice bran (Oryza sativa L.), and gamma-aminobutyric acid for the maintenance of normal cardiovascular function in subjects with mildly altered cholesterolemia: single-center, controlled, randomized, parallel-arm, double-blind clinical study with run-in periodISRCTN90678255
Effect of probiotic bacteria on decreasing seizures in children with refractory epilepsyEffect of GABA-producing probiotic bacteria on decreasing seizures in children with refractory epilepsyIRCT20240408061452N1
Evaluation of the Beneficial Effects of a Product Containing G-aminobutyric Acid (GABA) on Climacteric Syndrome DisordersValutazione Degli Effetti Benefici Di Un Prodotto Contenente Acido G-ammino Butirrico (GABA) Sui Disturbi Della Sindrome Climaterica CLIMATERICANCT06864520
GABA Biomarkers in Dravet SyndromeElectrophysiological Biomarkers of GABA Metabolism in Children With SCN1A+ Dravet SyndromeNCT05651204
Measurement of Glucose Metabolism in Humans: Effect of Recurrent Hypoglycemia on Hypothalamic GABAMeasurement of Glucose Metabolism in Humans Using Magnetic Resonance at 7 Tesla: Effect of Recurrent Hypoglycemia on Hypothalamic GABANCT02829593
Effect of GABA Supplementation in the Progression of Type 1 Diabetes in ChildrenDouble Blinded, Placebo Controlled Trial on the Effect of GABA Supplementation in the Progression of Type 1 Diabetes in ChildrenNCT01561508
Investigating the Role of Diazepam on Brain Function and Chemistry in Psychosis RiskEffect of Benzodiazepine on Corticolimbic Activation, GABA and Glutamate in Subjects at Clinical High Risk of PsychosisNCT06190483
Glycemic Index of GABA enriched Brown RiceEvaluation of Glycemic Index of GABA enriched Brown Rice (n=1) - NILCTRI/2023/06/054107
GABA Treatment in Subjects With Type 1 DiabetesA Randomised, Double-blind, Placebo-controlled, Parallel Group, Single-centre Trial of GABA Treatment in Subjects With Type 1 DiabetesNCT03721991
Effects of L-theanine and GABA on sleepBefore-after study on the effects of L-theanine and GABA on sleep in adults with sleep problems. - Before-after study on the effects of L-theanine and GABA on sleepJPRN-UMIN000050613
Impact of GABA-Enhancing Agents on Cortical GABA Concentrations Across the Menstrual Cycle in WomenThe Impact of GABA-Enhancing Agents on Cortical GABA Concentrations Across the Menstrual Cycle in WomenNCT00676026
Impact of GABA Probiotic Lactiplantibacillus Plantarum Lp815 on Sleep Outcomes in Participants with Self-Reported Sleep DisturbanceA Direct-to-Consumer, Randomized, Double-blind, Placebo-controlled Study Assessing the Impact of GABA Probiotic Lactiplantibacillus Plantarum Lp815 on Sleep Outcomes in Participants with Self-Reported Sleep DisturbanceNCT06789718
Quality of Life in Diarrhea-predominant Irritable Bowel Syndrome Taking GABAEvaluation of Quality of Life in a Cohort of Diarrhoeic Irritable Bowel Syndrome (IBS-D) Patients Assuming GABA.NCT06755489
Relative Oral Bioavailability of GABA From TomatoesPlasmakinetics of GABA From Tomatoes as Compared to GABA From a Supplement, After a Single Oral Administration in Healthy Young MenNCT04086108
A randomized, double-blind, placebo-controlled study of foodborne GABA for mild to moderate anxiety disordersA randomized, double-blind, placebo-controlled study of foodborne GABA for mild to moderate anxiety disordersChiCTR2400082462
Efficacy and biological mechanism of dietary gamma-aminobutyric acid in the adjunctive treatment of cognitive impairment in depressive disorder----double-blind randomized controlled studyEfficacy and biological mechanism of dietary gamma-aminobutyric acid in the adjunctive treatment of cognitive impairment in depressive disorder----double-blind randomized controlled studyChiCTR2400081252
Improvement Effects of Gamma Aminobutyric Acid(GABA) Supplementation on Treatment of Children With InsomniaImprovement Effects of Gamma Aminobutyric Acid(GABA) Supplementation on Treatment of Children With Insomnia, A Randomized, Placebo-controlled, Single-center, Intervention StudyNCT06226259
Innovative MRI to Localize the Epileptic ZoneQuantitative MRI and GABA Spectroscopy to Localize the Epileptic ZoneNCT06057233
The Protective Role of GABA Stimulation Before Ileostomy ClosureThe Protective Role of Preoperative Stimulation of the Distal Limb of the Ileostomy Loop With GABA Before Ileostomy ClosureNCT05905393
Enhancement of processing speed and accuracy of visual detection by GABA aspirationEnhancement of processing speed and accuracy of visual detection by GABA aspiration in the human brain - The clinical trial of GABA aspirationJPRN-UMIN000038851
Effectiveness of GABA Agonists in Reducing the Reinforcing Effects of CocaineGABA Agonists as Pharmacotherapies for Cocaine AbuseNCT00218166
Measurement of Changes in GABA Concentration in the Human Brain Following Rosmarinic Acid Administration Using Magnetic Resonance SpectroscopyMeasurement of Changes in GABA Concentration in the Human Brain Following Rosmarinic Acid Administration Using Magnetic Resonance Spectroscopy - Measurement of Changes in GABA Concentration in the Human Brain Following Rosmarinic Acid Administration Using Magnetic Resonance SpectroscopyJPRN-UMIN000054669
How Your Patients' Non-REM Sleep Changes On Sedatives in the Intensive Care UnitsComparison of Polysomnographic Findings in Mechanically Ventilated Patients Sedated With a2 Agonists Versus GABA AgonistsNCT00826553
The Use of Glutamic Acid Decarboxylase (GAD) and Gamma-Amino Butyric Acid (GABA) in the Treatment of Type I DiabetesThe Use of Glutamic Acid Decarboxylase (GAD)and Gamma-Amino Butyric Acid(GABA)in the Treatment of Type I Diabetes.NCT02002130
Glycemic Index testing of GABA enriched Brown Rice"""Evaluation of Glycemic Index of GABA enriched Brown Rice (n=1)"""CTRI/2022/11/047745
Probiotics for Anxiety StudyA Randomized, Double-blind, Placebo-controlled Study with Open-Label Extension Investigating the Effects of 2 Different Doses of GABA Probiotic Lp815 on Anxiety in Individuals with Mild to Moderate Anxiety in a Home SettingNCT06466603
A study for evaluating the effect of oral supplementation using gamma-aminobutyric acid (GABA) and whey protein on muscle hypertrophy in menA study for evaluating the effect of oral supplementation using gamma-aminobutyric acid (GABA) and whey protein on muscle hypertrophy in men - A study for evaluating the effect of oral supplementation using gamma-aminobutyric acid (GABA) and whey protein on muscle hypertrophy in menJPRN-UMIN000025842
A placebo controlled pilot study to explore the affects of GABA tea on children with autistic spectrum conditionsA double-blind, placebo-controlled, crossover-designed GABA tea pilot study in children diagnosed with Autism Spectrum ConditionsISRCTN72571312
"""The effect of herbal supplements on neurotransmitters in the formation of dementia""""""Evaluation of the possible effect of berberine supplementation on changes in serum levels of glutamate-dopamin-serotonin and GABA neurotransmitters in dementia patients"""IRCT20211012052739N1
A study for evaluating the effect of the intake of a GABA-containing food on stress and sleep in worker: randomized, placebo-controlled, double blind trialA study for evaluating the effect of the intake of a GABA-containing food on stress and sleep in worker: randomized, placebo-controlled, double blind trial - A study for evaluating the effect of the intake of a GABA-containing food on stress and sleep in workerJPRN-UMIN000019308
A study for evaluating the effect of the combined intake of GABA, extract of Hemerocallis fulva, and extract of Apocynum venetum on sleep: randomized, placebo-controlled, double blind traial, cross-over studyA study for evaluating the effect of the combined intake of GABA, extract of Hemerocallis fulva, and extract of Apocynum venetum on sleep: randomized, placebo-controlled, double blind traial, cross-over study - A study for evaluating the effect of the combined intake of GABA, extract of Hemerocallis fulva, and extract of Apocynum venetum on sleepJPRN-UMIN000023431
Assessment of Peripheral GABA Receptors for Local Pain ReliefVurdering af Perifere GABAA-receptorer Med Henblik på Lokal SmertelindringNCT02928328
Relative oral bioavailability of GABA from tomatoesplasmakinetics of GABA from tomatoes as compared to GABA from a supplement, after a single oral administration in healthy young menNL-OMON25547
A study for evaluating the effect of the intake of GABA at daytime on sleep: randomized, placebo-controlled, double blind trial, cross-over studyA study for evaluating the effect of the intake of GABA at daytime on sleep: randomized, placebo-controlled, double blind trial, cross-over study - A study for evaluating the effect of the intake of GABA at daytime on sleepJPRN-UMIN000030360
A study for evaluating the effect of the intake of a GABA-containing food on electroencephalography during sleep in adult males and femalesA study for evaluating the effect of the intake of a GABA-containing food on electroencephalography during sleep in adult males and females - A study for evaluating the effect of the intake of a GABA-containing food on electroencephalography during sleep in adult males and femalesJPRN-UMIN000026673
Individualised neuromodulation with transcranial direct current stimulation for motor recovery after strokeGABA-ergic intracortical function and its modulation by real and sham transcranial direct current stimulation during the sub-acute phase of recovery after ischaemic strokeACTRN12614001004651