| Effects of Sex Steroids on the Serotonin System | Effects of Sex Steroid Hormones on Serotonin Synthesis and Degradation Measured With PET | NCT02715232 |
| LUCID-201-001: A Double-Blind, Single Ascending Dose Study to Assess the Safety, Pharmacokinetics, and Pharmacodynamics of Lucid-201 in Healthy Male and Female Volunteers and Patients with Depressive Symptoms on a selective-serotonin reuptake inhibitor (SSRI) or a serotonin-norepinephrine reuptake inhibitor (SNRI) | A Double-Blind, Single Ascending Dose Study to Assess the Safety, Pharmacokinetics, and Pharmacodynamics of Lucid-201 in Healthy Male and Female Volunteers and Patients with Depressive Symptoms on a selective-serotonin reuptake inhibitor (SSRI) or a serotonin-norepinephrine reuptake inhibitor (SNRI) | ACTRN12623000423617 |
| The effect of medication for social anxiety disorder upon the production of chemical messengers in the brain | Serotonin-dopamine interactions in social anxiety disorder | ISRCTN66537707 |
| Ellagic acid in multiple sclerosis | The effect of Ellagic acid on depression, inflammatory index (IFN-?), oxidative (Nrf2) and nitrosative (NO) stress index, Brain Derived Neurotrophic Factor (BDNF), cortisol, serotonin and gene expression of indoleamine dioxygenase enzyme in patients with multiple sclerosis | IRCT20091114002709N54 |
| Combined Mirtazapine and SSRI Treatment of PTSD: A Placebo-Controlled Trial | Combined Mirtazapine and Selective Serotonin Reuptake Inhibitor (SSRI) Treatment of Post-traumatic Stress Disorder (PTSD) | NCT01178671 |
| The impact of antidepressants and genetic polymorphisms on emotion. | Impact of Escitalopram and Serotonin Transporter Polymorphisms on Emotion Processing and Regulation In Healthy Participants: A Randomised Controlled Trial | ACTRN12611000719932 |
| """The effect of herbal supplements on neurotransmitters in the formation of dementia""" | """Evaluation of the possible effect of berberine supplementation on changes in serum levels of glutamate-dopamin-serotonin and GABA neurotransmitters in dementia patients""" | IRCT20211012052739N1 |
| Comparing the efficacy of bupropion and amantadine on sexual dysfunction induced by a selective serotonin reuptake inhibitor | Comparing the efficacy of bupropion and amantadine on sexual dysfunction induced by a selective serotonin reuptake inhibitor | IRCT201409275280N17 |
| Observational study of placebo effect for a variable factor between individuals-reactive character mediated serotonin transporter genotype | Observational study of placebo effect for a variable factor between individuals-reactive character mediated serotonin transporter genotype - placebo effect for a variable factor between individuals | JPRN-UMIN000022301 |
| Effectiveness of the Dual Serotonin Norepinephrine Reuptake Inhibitor Venlafaxine in Depressed Patients | | ISRCTN87057460 |
| Fructose malabsorption and serotonin-associated psychological symptoms in children and adolescents | Fructose malabsorption and serotonin-associated psychological symptoms in children and adolescents - FIPsy | DRKS00031047 |
| Effect of Vitamin D Administration Along With SSRIs in Patients With Major Depressive Disorder | Effect of Vitamin D Administration Along With Selective Serotonin Reuptake Inhibitors (SSRIs) in Patients With Major Depressive Disorder (MDD) | NCT03754712 |
| ACP-103 to Treat Parkinson's Disease | 5HT2A/C Serotonin Blockade in Parkinson's Disease | NCT00086294 |
| Effect of Atypical Antipsychotic Drugs Olanzapine and Amisulpride on Glucose Metabolism | Effects of the Serotonin 2A Receptor on Insulin Sensitivity and Secretion: a Double-blind Controlled Comparison of Olanzapine vs. Amisulpride: | NCT01160991 |
| Effects of sex hormones on serotonin synthesis and degradation measured with positron emission tomography | Effects of sex steroid hormones on serotonin synthesis and degradation measured with PET - Effects of sex hormones on the serotonin system | EUCTR2015-000502-19-AT |
| Effects of consumption of the test food on blood serotonin in healthy subjects | Effects of consumption of the test food on blood serotonin in healthy subjects: an open-label study - Effects of consumption of the test food on blood serotonin in healthy subjects | JPRN-UMIN000053027 |
| EFFECT OF SEROTONIN AND LEVODOPA FUNCTIONAL RECOVERY IN PATIENTS WITH CEREBRAL INFARCTION | EFFECT OF SEROTONIN AND LEVODOPA FUNCTIONAL RECOVERY IN PATIENTS WITH CEREBRAL INFARCTION - SELEIS | EUCTR2014-000846-32-ES |
| Transdermal testosterone therapy: a potential treatment for selective serotonin reuptake inhibitor (SSRI)-associated sexual dysfunction in women. | Transdermal testosterone therapy: A potential treatment for selective serotonin reuptake inhibitor (SSRI) - associated sexual dysfunction in women being treated for depression | ACTRN12610001079033 |
| Comparison of Vitamin B12 Supplementation to Selective Serotonin Reuptake Inhibitor (SSRI) Versus SSRI Antidepressant Treatment Alone | Comparison of Vitamin B12 Supplementation and SSRI to SSRI Monotherapy in Treating Depression With Low Normal B12: A Randomized Open Label trialComparison of Vitamin B12 Supplementation to SSRI Versus SSRI Antidepressant Treatment Alone | NCT00939718 |
| The effects of Acute Tryptophan Depletion in individuals with a history of depression with and without anger attacks | The effects of Acute Tryptophan Depletion in individuals with a history of depression with and without anger attacks - Serotonin and depression | NL-OMON32412 |
| Effects of selective serotonin re-uptake inhibition on MOrbidity, mOrtality and mood in Depressed Heart Failure patients | Effects of selective serotonin re-uptake inhibition on MOrbidity, mOrtality and mood in Depressed Heart Failure patients | ISRCTN33128015 |
| Effect of Vitamin C Upon SSRI-treated OCD Patients | Effect of Vitamin C Upon Selective Serotonin Reuptake Inhibitors-treated Obsessive Compulsive Disorder Patients | NCT03754647 |
| effect of vitamin D on Autism Spectrum Disorders | Effect of vitamin D supplementation on core symptoms and serum biomarkers (serotonin and IL-6) in children with autism spectrum disorders | IRCT20131013014994N5 |
| Effect of Raha syrup on the severity of dependence, stress, anxiety, depression and craving and serum cortisol and serotonin levels in opium tincture addicts | Effect of Raha syrup on the severity of dependence, stress, anxiety, depression and craving and serum cortisol and serotonin levels in opium tincture addicts | IRCT20151228025732N62 |
| Telotristat Ethyl to Promote Weight Stability in Patients With Advanced Stage Pancreatic Cancer | Weight Loss in Patients With Advanced Stage Pancreatic Cancer: Role of Serotonin and Effects of Telotristat Ethyl | NCT03910387 |
| Mirtazapine for treatment resistant depression | A double blind placebo-controlled randomised trial of the addition of mirtazapine for patients with depression in primary care who have not responded to at least 6 weeks of treatment with a selective serotonin reuptake inhibitor or serotonin and noradrenaline reuptake inhibitor. | ISRCTN06653773 |
| The influence of hormone replacement therapy on the cerebral serotonin-1A receptor distribution and mood in postmenopausal women - Hormone replacement therapy and serotonin-1A receptors | The influence of hormone replacement therapy on the cerebral serotonin-1A receptor distribution and mood in postmenopausal women - Hormone replacement therapy and serotonin-1A receptors | EUCTR2007-005685-12-AT |
| The effect of vitamin D supplementation on patients with irritable bowel syndrome | Effects of supplementation with vitamin D on clinical outcomes, quality of life, anxiety, serum serotonin (5-hydroxytryptamine), 5-hydroxy-indole acetic acid and ratio of 5-HIAA/ 5-HT in Patient with irritable bowel syndrome the predominant form diarrhea | IRCT201701162709N42 |
| Study of lymphocyte neurotransmitter markers in depression and anxiety | A randomised study on the antidepressive effect of fluoxetine and folic acid, as possible augmenter, and the SYNThesis of serotonin (5-HT) in lymphocytes prior and after treatment | ISRCTN06123818 |
| Sumatriptan (a drug used for the treatment of migraine) and blood sugar | Effects of serotonin receptor agonism on blood glucose lowering: Proof of concept in humans | ISRCTN13848689 |
| A first-in-human single-dose escalation study of the safety, pharmacokinetics and pharmacodynamics of the test drug including brain Serotonin Receptor Transporter (SERT) occupancy by Positron Emission Tomography (PET). | A first-in-human single-dose escalation study of the safety, pharmacokinetics and pharmacodynamics of the test drug including brain Serotonin Receptor Transporter (SERT) occupancy by Positron Emission Tomography (PET). - new drug SRD/PET study. | NL-OMON34991 |
| Serotonin in Impulse Control Disorders in Parkinson's Disease | Role of the Serotoninergic System in Impulse Control Disorders in Parkinson's Disease | NCT03970239 |
| The effect of selective serotonin reuptake inhibitors (SSRIs) on the circadian light response | The effect of a single dose of Citalopram compared to placebo on the circadian systems response to light in healthy adults. | ACTRN12614000807651 |
| Effect of zinc in treatment of depression | Zinc’s effect on therapeutic efficacy of selective serotonin re-uptake inhibitor drugs in depressed patients | IRCT20150706023084N2 |
| Effect of supplementary oral 5-hydroxytryptophan on severity of depression in patients on chronic selective serotonin reuptake inhibitors; a clinical trial | The effect of supplementary oral 5-hydroxytriptophan plus other essential elements (Dr Daniel capsule) on severity of depression, quality of life and the level of urinary 5-Hydroxyindoleacetic acid in patients with major depression on chronic selective serotonin reuptake inhibitors | ACTRN12613001275752 |
| Cholecalciferol on Depressive Symptoms in Type 2 Diabetes Mellitus Patients | Effects of Cholecalciferol on Depressive Symptoms in Type 2 Diabetes Mellitus Patients: Study of Neurotrophin-3, Serotonin, and C-Peptide | NCT04917458 |
| Hyaluronic Acid Injection in the Glans Penis Versus Selective Serotonin Reuptake Inhibitors for Lifelong Premature | Hyaluronic Acid Injection in the Glans Penis Versus Selective Serotonin Reuptake Inhibitors for Lifelong Premature: A Randomized Controlled Trial | NCT06451406 |
| The Effect of Vitamin D on Attention Deficit Hyperactivity Disorder | The effect of vitamin D supplementation on inflammatory cytokines (Interleukin 6, Tumor Necrosis Factor alpha), Brain-derived neurotrophic factor (BDNF), Dopamine, Serotonin, Paroxonase-1 enzyme (PON-1),Total Antioxidant Capacity (TAC), 8-Isoprostane, Soluble intercellular adhesion molecule-1(sICAM-1) and Soluble vascular cell adhesion molecule-1(sVCAM-1) in school- aged children with Attention Deficit Hyperactivity Disorder | IRCT2016102324081N2 |
| Serum Serotonin and Pruritus After Intrathecal Morphine in Cesarean Section | Pruritus After Intrathecal Morphine in Cesarean Section: Incidence, Severity and Its Relation to Serum Serotonin Level | NCT03209427 |
| Effects of a music therapy protocol on communication of Brazilian children with autistic disorder: a randomized controlled study | The effects of a music therapy intervention protocol on the communication of Brazilian boys with autistic disorder measured by the scale Children's Communication Checklist 2 (CCC-2), video analysis and analysis of gene expression in the receptors of serotonin, dopamine, oxytocin and vasopressin | ACTRN12610000804088 |
