| Effect of caffeine and citrulline malate on resistance exercise and jumping performance: a randomized double-blind placebo-controlled crossover study | Effect of isolated and combined ingestion of caffeine and citrulline malate on resistance exercise and jumping performance: a randomized double-blind placebo-controlled crossover study | ISRCTN11694009 |
| Pilot study to investigate the anti-inflammatory effects of caffeine in subjects with chronic obstructive pulmonary disease (COPD) | Pilot study to investigate the anti-inflammatory effects of caffeine in subjects with chronic obstructive pulmonary disease (COPD) - Anti-inflammatory effects of caffeine in COPD | NL-OMON31548 |
| Examining Caffeine as a Treatment for Antidepressant-induced Arousal Dysfunction in Women | Examining Caffeine as a Treatment for Antidepressant-induced Arousal Dysfunction in Women | NCT05685407 |
| Maxalt 10mg Plus Caffeine 75mg in the Acute Treatment of Migraine Headache | Maxalt 10mg Plus Caffeine 75mg in the Acute Treatment of Migraine Headache | NCT00471952 |
| The Impact of Caffeine on Brachial Endothelial Function in Healthy Subjects and in Patients With Ischemic Heart Disease | The Impact of Caffeine on Brachial Endothelial Function in Healthy Subjects & in Patients With Ischemic Heart Disease | NCT00564824 |
| Prevention and treatment effect of traditional Chinese medical five-tone therapy combined with caffeine citrate on apnea of prematurity | Prevention and treatment effect of traditional Chinese medical five-tone therapy combined with caffeine citrate on apnea of prematurity | ChiCTR2300067524 |
| A Study to Compare How Different Substances (Caffeine, Warfarin, Omeprazole, Metoprolol, and Midazolam) Are Handled by the Body of Healthy People and People With Liver Cirrhosis | Profiling Study for the Hepatic Cytochrome P450 (CYP) Isozymes CYP1A2, CYP2C9, CYP2C19, CYP2D6 and CYP3A in Healthy Subjects and in Patients With Stage 4 (F4) Liver Fibrosis / Cirrhosis by the Combined Administration of the Probe Substrates (the Cocktail) Caffeine, Warfarin, Omeprazole, Metoprolol, and Midazolam | NCT05741385 |
| Muscle Glycogen Synthesis When Caffeine and Protein is Co-Ingested With Carbohydrates | The Effect of Caffeine or Protein Co-ingestion With Carbohydrate on Post-exercise Muscle Glycogen Synthesis Rate. | NCT00975390 |
| Efficacy of Caffeine, With and Without Biperiden, in the Detoxification of Cocaine Dependent Patients | Efficacy of Caffeine, With and Without Biperiden, in the Detoxification of Cocaine Dependent Patients | NCT00495092 |
| Efficacy of Caffeine, With and Without Biperiden, as a Maintenance Treatment for Cocaine Dependence | Efficacy of Caffeine, With and Without Biperiden, as a Maintenance Treatment for Cocaine Dependence | NCT00495183 |
| Effects of Low Doses of Caffeine on Mood, Physiology and Mental Function | Levels of Caffeine Lower Than Those Found in Decaffeinated Beverages Exert Effects on Cognition, Mood, and Autonomic Activity | NCT00487227 |
| The Effects of Caffeine and L-theanine Both Alone and in Combination on Cerebral Blood Flow, Cognition and Mood | A Randomised, Double Blind, Placebo-controlled Study to Evaluate the Effects of Caffeine and L-theanine Both Alone and in Combination on Cerebral Blood Flow, Cognition and Mood. | NCT00981955 |
| The short term effects of coffee and caffeine on the cardiovascular and autonomic nervous systems | The short term effects of coffee and caffeine on the cardiovascular and autonomic nervous systems: a crossover, double blind, placebo-controlled and cohort randomised clinical trial | ISRCTN11339389 |
| The effect of additional loading dose of caffeine-citrate prior ro extubation | The effect of additional pre-extubational loading dose of caffeine-citrate - NEOKOFF22 | EUCTR2022-003202-77-HU |
| Effects of Caffeine in Tinnitus | Effects of Caffeine Consumption on Tinnitus Perception | NCT00628316 |
| CLINICAL PHASE III MULTI-CENTRIC, DOUBLE-BLIND, DOUBLE DUMMY, RANDOMISED STUDY TO COMPARE SAFETY AND EFFICACY OF DOPRAM® (DOXAPRAM HYDROCHLORIDE) TO CAFEINE COOPER (CAFFEINE CITRATE) IN THE TREATMENT OF APNOEIC PREMATURE BABIES | CLINICAL PHASE III MULTI-CENTRIC, DOUBLE-BLIND, DOUBLE DUMMY, RANDOMISED STUDY TO COMPARE SAFETY AND EFFICACY OF DOPRAM® (DOXAPRAM HYDROCHLORIDE) TO CAFEINE COOPER (CAFFEINE CITRATE) IN THE TREATMENT OF APNOEIC PREMATURE BABIES | EUCTR2007-002567-27-DE |
| Drug Interaction Study With a Potential Alzheimer's Disease Compound | Effect of Concomitant Administration of BMS-708163 on the Pharmacokinetics of Midazolam, Warfarin, Caffeine, Omeprazole and Dextromethorphan in Healthy Male Subjects by Administration of a Modified Cooperstown Cocktail | NCT00726726 |
| Consequences of Caffeine Intake in Sleep Restricted Teenagers | Consequences of Caffeine Intake in Teenagers: Effects on Sleep, Reward Processing, Risk Taking, and Underlying Cerebral Mechanisms Under Conditions of Sleep Restriction | NCT05790161 |
| Caffeine and Cocaine | Experiment 1: Adenosine Receptor A2A Antagonists and Cocaine Dependence | NCT00733993 |
| Caffeine Reduction and Overactive Bladder Symptoms | Caffeine Reduction Education And Overactive Bladder Symptoms | NCT00754260 |
| ??Effect of Caffeine injection on pain after Cholecystectomy | The effect of intravenous injection of Caffeine on reducing pain after laparoscopic Cholecystectomy | IRCT20221205056716N1 |
| Phase II study of caffeine combined chemotherapy in patients with high- grade bone and soft tissue tumor | Phase II study of caffeine combined chemotherapy in patients with high- grade bone and soft tissue tumor - Caffeine combined chemotherapy for high- grade bone and soft tissue tumor pII | JPRN-UMIN000001094 |
| Comparison of Caffeine Reduction and Anticholinergic Medications for Treatment of Overactive Bladder | Comparison of Caffeine Reduction and Anticholinergic Medications for Treatment of Overactive Bladder | NCT00780832 |
| Efficacy of ONE A DAY Weightsmart Advanced Versus Caffeine and Placebo on Energy Expenditure, Thermogenesis and Perceived Energy Levels in Women. | A Randomized, Single Center, Double-blind, Three-way Crossover Trial to Evaluate the Efficacy of ONE A DAY Weightsmart Advanced Versus Caffeine and Placebo on Energy Expenditure, Thermogenesis and Perceived Energy Levels in Women. | NCT00781586 |
| A study to determine safety of Caffeine tablets | An Open Label Balanced Randomized Two Treatment Two Period Two Sequence Crossover Comparative Bioavailability study of Caffeine Immediate Release Tablets 400 Mg Comparing with Caffeine Modified Release Tablets 400 Mg Of Bioplus Lifesciences Pvt Ltd India In Normal Healthy Adult Human Male Subjects Under Fasting Conditions | CTRI/2023/02/049999 |
| Caffeine and Hypoxia During Exercise in Males and Females | Sex Differences in the Acute Effects of Caffeine Supplementation on Exercise in Normobaric Hypoxia | NCT05764018 |
| Determine the Effect of Multiple Doses of AZD7325, CYP Study | A Phase I Open-Labeled, Fixed Sequence Study to Determine the Effect of Multiple Doses of AZD7325 on the Pharmacokinetics of Midazolam (CYP3A4) and Caffeine (CYP1A2) | NCT00790114 |
| MRI and Neurodevelopment in Preterm Infants Following Administration of High-Dose Caffeine | Magnetic Resonance Imaging and Neurodevelopmental Outcomes in Preterm Infants Following Administration of High-Dose Caffeine - A Pilot Study | NCT00809055 |
| Caffeine Versus Placebo for Spinal Headaches | A Prospective Trial of IV Caffeine vs Placebo for Post-Dural-Puncture Headache in the Emergency Department | NCT00809627 |
| The Effect of Caffeine Reduction on Snoring and Quality of Life | The Effect of Caffeine Reduction on Snoring and Quality of Life | NCT00641810 |
| Effect of Multiple Doses of AZD6280 on the Pharmacokinetics of Midazolam (CYP3A4) and Caffeine (CYP1A2) | A Phase I Open-labeled, Fixed Sequence Study to Determine the Effect of Multiple Doses of AZD6280 on the Pharmacokinetics of Midazolam (CYP3A4) and Caffeine (CYP1A2) | NCT00824057 |
| Anti-inflammatory Effects of Caffeine in Chronic Obstructive Pulmonary Disease (COPD) Subjects | Pilot Study to Investigate the Anti-inflammatory Effects of Caffeine in Subjects With Chronic Obstructive Pulmonary Disease (COPD) | NCT00826566 |
| Caffeine's Effect on Regadenoson Administration With Single Photon Emission Computed Tomography (SPECT) Myocardial Perfusion Imaging (MPI) | A Phase 3b, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Effect of Caffeine Intake on Single Photon Emission Computed Tomography (SPECT) Myocardial Perfusion Imaging (MPI) in Subjects Administered Regadenoson | NCT00826280 |
| The effect of caffeine on cognitive performance and brain activity following a ‘real life’ workday - an fMRI title. | The effect of caffeine on cognitive performance and brain activity following a ‘real life’ workday - an fMRI title. | NL-OMON20613 |
| The effect of two dosages of theobromine and caffeine on mood and cognition in healthy subjects | The effect of two dosages of theobromine and caffeine on mood and cognition in healthy subjects - 08063V theobromine and caffeine | NL-OMON33090 |
| Comparing Effect of Gabapentin and Caffeine on Treatment of Headache Following Spinal Anesthesia | Comparing Effect of Gabapentin and Caffeine on Treatment of Headache Following Spinal Anesthesia in Women Candidate for Cesarean Section | IRCT20210314050703N2 |
| Efficacy of Caffeine Injection as an Adjuvant to Opioid Therapy in Cancer Pain | Efficacy of Caffeine as an Adjuvant to Opioid Therapy in Cancer Pain: a Randomized, Double-blind, Placebo-controlled Trial | NCT00879775 |
| AZD2066 Cocktail Study | A Phase I, Open Label, Multi Centre Study in Healthy Volunteers to Estimate the Effect of Multiple Doses of AZD2066 on the Activity of CYP1A2, CYP2B6, CYP2C9, CYP2C19, CYP2D6 and CYP3A4 by Administering a Cocktail of Caffeine, Bupropion, Tolbutamide, Omeprazole, Metoprolol and Midazolam | NCT00930306 |
| Evaluation of safety and the effectiveness of Caffeine Plus Irox anti-hair loss serum and shampoo | Evaluation of safety and the effectiveness of Caffeine Plus Irox anti-hair loss line (serum and shampoo) produced by Iran Avandfar company In the prevention and treatment of androgenic hair loss | IRCT20190210042676N13 |
| A observational study to assess the effectiveness of sphenopalatine ganglion block and tb caffiene in treatment of Post dural pucture headache FOLLOWING lower segment ceaserean section | """A COMPARATIVE CLINICAL STUDY TO ASSESS THE EFFECTIVENESS OF SPHENOPALATINE GANGLION BLOCK AND ORAL CAFFEINE IN MANAGEMENT OF POSTDURAL PUNCTURE HEADACHE FOLLOWING LOWER SEGMENT CESAREAN SECTION""." | CTRI/2022/10/046747 |
| Correlation between clinical effect of caffeine citrate on apnea in preterm infants and adenosine receptor gene polymorphism | Correlation between clinical effect of caffeine citrate on apnea in preterm infants and adenosine receptor gene polymorphism | ChiCTR2100050212 |
| The Caffeine, Postoperative Delirium, and Change in Outcomes After Surgery (CAPACHINOS-2) Study | The Caffeine, Postoperative Delirium, and Change in Outcomes After Surgery (CAPACHINOS-2) Study | NCT05574400 |
| Effect of Caffeine Versus Probiotic on Preterm Neonates With Bronchopulmonary Dysplasia | Caffeine Versus Probiotic as Adjuvant Therapy for Preterm Neonates With Bronchopulmonary Dysplasia | NCT05682807 |
| The effect of caffeine on Chronic Fatigue Syndrome caused by COVID-19 | The effect of caffeine on Chronic Fatigue Syndrome caused by COVID-19 | RBR-9bxptps |
| The Effect of Leptin A-200, Caffeine/Ephedrine and Their Combination Upon Weight Loss and Body Composition in Man | The Effect of Leptin A-200, Caffeine/Ephedrine and Their Combination Upon Weight Loss and Body Composition in Man | NCT01710722 |
| Comparison of the effect of caffeine and doxapram on respiratory parameters of patients after spinal surgery | Comparative study of the effect of caffeine and doxapram on respiratory parameters of patients admitted to intensive care units after spinal surgery | IRCT20200825048515N51 |
| Caffeine Optimization Versus Standard Caffeine Dosage (2B-2) | A Head-to-Head Comparison of the 2B-Alert Caffeine Optimization Algorithm Versus Standard Caffeine Dosing on Performance During Sleep Deprivation (2B-2) | NCT05588934 |
| Effects of caffeine dose on bowel function recovery following gynecologic cancer surgery: A randomized double-blind controlled trial | Effects of caffeine dose on bowel function recovery following gynecologic cancer surgery: A randomized double-blind controlled trial | TCTR20221001002 |
| Effect of acute caffeine intake on rating of perceived exertion, muscle pain and fatigue during exercise in women with fibromyalgia | Effect of acute caffeine intake on perceptive responses, muscle oxygenation and neuromuscular fatigue development during exercise in women with fibromyalgia | RBR-9n9yq4p |
| Effects of Caffeine on Anxiety, Emotional Processing, Approach-avoidance Behavior, and Interoception in Panic Disorder | Effects of Caffeine on Anxiety, Emotional Processing, Approach-avoidance Behavior, and Interoception in Panic Disorder - a Double Blind Randomized Controlled Study | NCT05261594 |
| Investigating the effect of caffeine to improve neurodevelopmental outcomes in babies born late preterm: a randomised controlled trial | Investigating the effect of caffeine to improve neurodevelopmental outcomes in babies born late preterm: a randomised controlled trial | ACTRN12622001344785 |
| Caffeine Supplementation, Resistance Training and Blood Antioxidant Status | Acute Effects of Caffeine Supplementation on Resistance Training Volume and Blood Antioxidant Status in Resitance Trained Men | NCT05230303 |
| CaffeinICU Study - A Study on Oral Caffeine in ICU Patients With Coma | CaffeinICU Study - A Multi-centre Pilot Study to Examine the Safety and Feasibility of Oral Caffeine in Critically Ill Adult Patients With Low Glasgow Coma Scale Score. | NCT05232734 |
| Does paraxanthine provide greater improvement in cognitive function than caffeine or in combination with caffeine prior to and following running? | Effects of ParaXanthine supplementation with and without CAffeine on executive Function (PXCAF) | ISRCTN14506218 |
| Study of the effect of caffeine consumption on the efficiency of surgical closure | Study of the effect of caffeine consumption on the efficiency of surgical closure - coffee | JPRN-jRCT1040210117 |
| Pilot Study Characterizing the Pharmacokinetic Profile of a Novel Encapsulated Caffeine Beverage in the Fed and Fasted States | Pilot Study Characterizing the Pharmacokinetic Profile of a Novel Encapsulated Caffeine Beverage in the Fed and Fasted States | NCT05266248 |
| Evaluation of the effect of caffeine on separation from ventilators of patients admitted to the intensive care unit | Evaluation of the effect of oral caffeine in helping to liberate (Liberation) from the ventilator in intubated and mechanically ventilated patients admitted to the intensive care unit | IRCT20210110049990N2 |
| PK and Safety of Caffeine in Neonates With Hypoxic Ischemic Encephalopathy Receiving Therapeutic Hypothermia | Pharmacokinetics (PK) and Safety of Caffeine in Neonates With Hypoxic Ischemic Encephalopathy Receiving Therapeutic Hypothermia | NCT05295784 |
| Does Caffeine Facilitate Human Reward Learning Behaviors? | Caffeine and Reward Learning: Characterizing Behavioral Expression of Adenosine-Dopamine Interaction | NCT05325502 |
| Influence of Caffeine Consumption on the Human Circadian System | Influence of Caffeine Consumption on the Human Circadian System: Neurobehavioral, Hormonal and Cerebral Mechanisms | NCT05409339 |
| Individualization of caffeine supplementation in sports based on the analysis of heart rate variability (HRV) | Individualization of caffeine supplementation in adult athletes aged 18 to 30 based on the analysis of HRV | ACTRN12622000823774 |
| Evaluation of the penetration of caffeine from caffeine-containing shampoos into the skin and hair follicles | Evaluation of the penetration of caffeine from caffeine-containing shampoos into the skin and hair follicles - Caffeine_HF | DRKS00029226 |
| Impact of Intravenous Caffeine on Atrial Electrical Properties and Potential Arrythmia Induction | Impact of Intravenous Caffeine on Atrial Electrical Properties and Potential Arrythmia Induction in Patients With Paroxysmal Atrial Fibrillation: The COFFEE-AF Trial | NCT05464940 |
| Effect of prophylactic caffeine on the sleep/wake cycles (SWC) in preterm neonates. | Effect of prophylactic caffeine on the sleep/wake cycles (SWC) in preterm neonates with RDS treated with nasal CPAP with a gestational age of 28-35 weeks. | IRCT20170627034782N3 |
| The Caffeine Therapy in the Fetal to Neonatal Transition | The Caffeine Therapy in the Fetal to Neonatal Transition in Preterms | NCT05454332 |
| A multicenter randomized controlled study on the protective effect of early preventive use of caffeine citrate on the brain of premature infants | A multicenter randomized controlled study on the protective effect of early preventive use of caffeine citrate on the brain of premature infants | ChiCTR2200057419 |
| Caffeine Citrate Use and Electronic Activity of the Diaphragm (EDI) Changes | Changes in Diaphragmatic Activity Before and After Caffeine Citrate Administration and Discontinuation | NCT05393817 |
| A study of the nocebo effect of caffeine: differences in expression with and without explanation and interindividual variability factors. | A study of the nocebo effect of caffeine: differences in expression with and without explanation and interindividual variability factors. - A study of the nocebo effect of caffeine | JPRN-UMIN000047526 |
| Caffeine Intake Inrelation to Perioperative Analgesic Consumption | Effect Of Daily Caffeine Intake On Perioperative Analgesic Consumption And Recovery Time In Patients Undergoing Laparoscopic Surgeries. | NCT05330754 |
| Effect of standard vs high dose of caffeine on organ flows in neonates | Hemodynamic effects of high versus standard loading dose of caffeine: A Randomized Controlled trial | CTRI/2022/03/041479 |
| A Study to Learn How Well a Single Dose of the Study Treatment Naproxen Sodium and Caffeine Combined in One Tablet (Fixed-dose Combination) Works to Relieve Pain After Dental Surgeries Compared to the Single Ingredients and to Placebo | A Randomized, Double-Blind, Single-Dose, Parallel, Placebo-Controlled Pivotal Trial to Confirm the Efficacy of a Fixed Dose Combination Tablet of Naproxen Sodium and Caffeine to Effectively Alleviate Postsurgical Dental Pain | NCT05485805 |
| """Pecos"" B-adrenergic and PPAR-G Stimulation Upregulates Lipid Metabolism in Human Subcutaneous Fat" | Synergistic Induction of UCP-1 by Ephedrine/Caffeine and Pioglitazone: A Rationale for Combination Therapy of Obesity | NCT00377975 |
| The effect of caffeine on post-appendectomy pain | The effect of caffeine versus placebo on post-appendectomy pain | IRCT20220507054763N2 |
| The Pharmacodynamics of Cannabinoid-Caffeine Combinations | A Double-Blind, Randomized, Placebo-Controlled, Within-Subject Crossover Study of the Effects of Combinations of Cannabinoids and Caffeine | NCT05478863 |
| A Phase 1, Open-Label, Fixed Sequence Drug-Drug Interaction Study to Assess the Effect of Multiple Doses of Oral THB001 on the Pharmacokinetics of Oral Caffeine, Omeprazole, and Midazolam (CYP1A2, CYP2C19 and CYP3A4 probe substrates) in Healthy Volunteers | A Phase 1, Open-Label, Fixed Sequence Drug-Drug Interaction Study to Assess the Effect of Multiple Doses of Oral THB001 on the Pharmacokinetics of Oral Caffeine, Omeprazole, and Midazolam (CYP1A2, CYP2C19 and CYP3A4 probe substrates) in Healthy Volunteers - CS0376-210320 | NL-OMON51382 |
| The Acute Effects of Exercise and Caffeine on Working Memory During Acute Caffeine Deprivation | Comparing the Acute Effects of Exercise and Caffeine on Working Memory During a Short Period of Caffeine Deprivation in Moderate to Heavy Caffeine Consumers | NCT05170464 |
| The Effects of Caffeine on Physical Performance of Ice Hockey Players | The Effects of Caffeine on Physical Performance of Ice Hockey Players: A Cross-over Randomized Controlled Trial | NCT05170139 |
| A Study to Estimate the Effect of Multiple Dose Abrocitinib on Caffeine, Efavirenz, and Omeprazole in Healthy Participants | A PHASE 1, OPEN-LABEL, FIXED-SEQUENCE, 2-PERIOD STUDY TO ESTIMATE THE EFFECT OF MULTIPLE DOSE ABROCITINIB ON THE PHARMACOKINETICS OF SINGLE DOSES OF CAFFEINE, EFAVIRENZ, AND OMEPRAZOLE IN HEALTHY PARTICIPANTS | NCT05067439 |
| How long is caffeine duration enough for preterm infants? | Effect of short course caffeine on recurrence of apnea of prematurity in preterm infants =32 weeks- A randomized controlled trial | CTRI/2021/09/036141 |
| Piperine effect on caffeine salivary concentration | The role of piperine on the salivary concentration of caffeine as a main CYP1A2 probe | IRCT201209239271N3 |
| Theanine and Caffeine on Neurophysiology of Attention | Neurophysiological Correlates of L-theanine, Caffeine and Their Combination on Improving Selective Attention in a Visual Reaction Time Task: A Functional Magnetic Resonance Imaging (fMRI) Study | NCT02770105 |
| The efficacy of caffeine in restoring cognitive declines across 24 hours of sustained wakefulness | The efficacy of caffeine in restoring cognitive declines across 24 hours of sustained wakefulness in healthy adults | ACTRN12622001503718 |
| A feasibility study to suppress myocardial [18F]-FDG uptake by pre-administration of pure caffeine | A feasibility study to suppress myocardial [18F]-FDG uptake by pre-administration of pure caffeine - PET Caffeine study | NL-OMON51725 |
| Evaluation of low versus high maintenance dose caffeine on respiratory function in preterm infant. | Evaluation of low versus high maintenance dose caffeine on respiratory function in preterm infants with gestational age <34 weeks. | IRCT20160523028008N17 |
| Does Caffeine Affect the Sensitivity of Adenosine Perfusion Scans? | Does Caffeine Affect the Sensitivity of Adenosine Perfusion Scans? | NCT00205166 |
| The Effect of Caffeine on Postextubation Adverse Respiratory Events in Children With Obstructive Sleep Apnea (OSA). | A Pilot Study to Evaluate if Caffeine Helps Children With Obstructive Sleep Apnea Recover Faster From Anesthesia, and With Less Complications After General Anesthesia for Tonsillectomy and Adenoidectomy. | NCT00273754 |
| Effects of caffeine on people suffering from intermittens claudication. Three double blinded, placebo-controlled cross-over studies and a follow-up study. - Caffeine and intermittens claudicatio | Effects of caffeine on people suffering from intermittens claudication. Three double blinded, placebo-controlled cross-over studies and a follow-up study. - Caffeine and intermittens claudicatio | EUCTR2006-001902-10-DK |
| Assessment and Treatment of Caffeine Dependence | | NCT00338195 |
| Effect on Energy Metabolism at Cellular Level of Diet Plus Treatment With Ephedrine and Caffeine in Obesity | Evaluation of Diet and Treatment With a Combination of Ephedrine and Caffeine on Thermogenesis, Cardiac Function and on Uncoupling Proteins Expression in Adipose and Muscle Tissue of Morbid Obese Patients Undergoing Bariatric Surgery. | NCT02048215 |
| Experimental Studies of the Effects of Caffeine on Glucose Regulation | Caffeine and Glucose Regulation | NCT00432887 |
| The effect of caffeine on attention | The effect of caffeine on attention - Caffeine*s effect on attention | NL-OMON41150 |
| The Effect of Caffeine on Ischemic Preconditioning | Caffeine Reduces Acute Ischemic Preconditioning | NCT00184912 |
| An investigation into the effects of glucose and caffeine on multitasking, mood and fMRI | An investigation into the effects of glucose and caffeine on multitasking, mood and fMRI regional activation in healthy adults. | ACTRN12612000202864 |
| Effect of the timing of low-dose caffeine on 3-point shooting accuracy in college basketball players. | Effect of the timing of low-dose caffeine (3mg/kg body mass) on 3-point shooting accuracy in college basketball players. | ACTRN12621001308886 |
| The effect of caffeine restriction on enuresis | The effect of caffeine restriction on enuresis in children 6 to 15 years old | IRCT20180401039167N3 |
| Drug-Drug Interaction Study Between EDP-235, Midazolam, Caffeine and Rosuvastatin in Healthy Subjects | A NON-RANDOMIZED, MULTIPLE-DOSE, OPEN-LABEL, SINGLE SEQUENCE STUDY TO EVALUATE THE EFFECT OF CONCOMITANT ADMINISTRATION OF EDP-235 ON THE PHARMACOKINETICS AND SAFETY OF MIDAZOLAM, CAFFEINE, AND ROSUVASTATIN IN HEALTHY PARTICIPANTS | NCT05594615 |
| The effect of caffeine on estimates of persistent inward currents in human motor units | The effect of caffeine on estimates of persistent inward currents in healthy human motor units | ACTRN12621001665820 |
| The Dose and Timing Relationship Between Caffeine and Subsequent Sleep Quantity and Quality | The Dose and Timing Relationship Between Caffeine and Subsequent Sleep Quantity and Quality in Healthy Adults | ACTRN12621001625864 |
| Evaluation of tolerability and analgesic activity of paracetamol 1000 mg+caffeine 130 mg in the treatment of tension-type headache. Randomized, double blind, double-dummy, cross-over study vs. naproxene 550 mg and placebo. | Evaluation of tolerability and analgesic activity of paracetamol 1000 mg+caffeine 130 mg in the treatment of tension-type headache. Randomized, double blind, double-dummy, cross-over study vs. naproxene 550 mg and placebo. | EUCTR2004-000850-22-IT |
| Caffeine Dose and Autonomic Recovery | Effect of caffeine dose on heart rate variability, rate pressure product and some fatigue indexes after endurance exercise in trained men | IRCT20190720044283N4 |
| Clinical study to evaluate the Efficacy & Safety of test drug, Caffeine Citrate Injection USP 20 mg/ml of in the treatment of Apnea of preterm infants | A Prospective, Interventional, Randomised, Double blind, Parallel Group, Comparative Clinical study to evaluate the Efficacy & Safety of test drug, Caffeine Citrate Injection USP 20 mg/ml of Swiss Parenterals Ltd., in the comparison to reference drug, Peyona 20mg/ml of Chiesi Pharmaceuticals GmbH, Austria in the treatment of Apnea of preterm infants | CTRI/2021/10/037536 |
| Effect of concurrent of curcumin and caffeine on non-alcoholic fatty liver disease | Evaluation the Effect of concurrent of curcumin and caffeine on biochemical markers,oxidative stress, and inflammatory cytokines in individuals with non-alcoholic fatty liver disease (Random Clinical trial Study) | IRCT20240715062438N1 |
| Short term effects of low caffeine energy drinks on blood vessel and heart functions in healthy volunteers | Acute effects of low caffeine energy drinks on endothelial and myocardial functions in healthy volunteers | ISRCTN40313372 |
| DeCaf-Me: Can delirium be prevented with caffeine and melatonin? A randomised, placebo-controlled trial | DeCaf-Me: Can delirium be prevented with caffeine and melatonin? A randomised, placebo-controlled trial | ACTRN12621001633875 |
| The Effect of Caffeine in Elderly Citizens | The Effect of Caffeine as Endurance Enhancing Drug in the Elderly | NCT00117520 |
| Caffeine in the Prevention of Post-operative Nausea and Vomiting | A Prospective, Randomized, Double-blind, Placebo-controlled Study of Caffeine in the Prevention of Post-operative Nausea and Vomiting in Patients Undergoing Ambulatory Surgery Under General Anesthesia | NCT00130026 |
| Does caffeine enhance the circadian light sensitivity in the human retina? | Does caffeine enhance the circadian light sensitivity in the human retina? | DRKS00027398 |
| Coronary Care Caffeine: Influence of Coffee on Heart Rate Post Myocardial Infarction | Influence of Coffee on Heart Rate Variability Post Myocardial Infarction | NCT00137098 |
| Individual and additive effects of blackcurrant juice and caffeine intake on high-intensity intermittent exercise performance in physically active healthy male volunteers | Individual and additive effects of blackcurrant juice and caffeine intake on high-intensity intermittent exercise performance in physically active healthy male volunteers | ACTRN12621001394831 |
| Evaluation of the Potential CYP1A2-mediated Drug Drug Interaction Safety, and Tolerability of ABX464 | A Two Part, Fixed-sequence, Open-label Crossover Study to Evaluate Potential CYP1A2-mediated Drug-drug Interactions of ABX464 in Healthy Subjects Using Caffeine and Fluvoxamine as Probe Drugs | NCT05121714 |
| Can Caffeine prevent the cessation of breathing in preterm newborn babies? | Comparing the prophylactic effects of Caffeine versus placebo on the apnea of prematurity in neonates of Kabul City: A randomized clinical trial | ACTRN12621001000897 |
| The effects of caffeine supplementation on clinical parameters and disease severity in patients with hepatic cirrhosis | The effects of caffeine supplementation on clinical parameters and disease severity in patients with hepatic cirrhosis | IRCT20100524004010N34 |
| Randomized controlled trial of anti-stress effect of low-caffeine green tea on students during pharmacy practice | Randomized controlled trial of anti-stress effect of low-caffeine green tea on students during pharmacy practice - Anti-stress effect of low-caffeine green tea | JPRN-UMIN000014942 |
| Caffeine, DNA and Cognition | Acute Caffeine Intake, Cognition and DNA Study | NCT05806476 |
| The effect of additional pre-extubational loading dose of caffeine-citrate | The effect of additional pre-extubational loading dose of caffeine-citrate - NEOKOFF22 | CTIS2024-519041-29-02 |
| Investigating the Acute and Chronic Effects of a Supplement Containing Caffeine, Vitamins, Minerals and Botanical Extracts on Cognition, Sleep and Wellbeing, in Healthy Volunteers | Investigating the Acute and Chronic Effects of a Supplement Containing Caffeine, Vitamins, Minerals and Botanical Extracts on Cognition, Sleep and Wellbeing, in Healthy Volunteers. | NCT06780774 |
| Comparison of the effectiveness of high-dose regimens and standard regimens of Caffeine in premature infants | Comparison of therapeutic effects and possible side effects of high dose regimens and standard regimens of Caffeine Citrate in premature neonates | IRCT20240929063207N1 |
| To compare the effectiveness of high doses versus low dose of caffeine given before removing breathing tubes in newborns on ventilators to see which helps them breathe on their better own. | Efficacy of Pre-extubation High Dose vs Low Dose Caffeine Administration For Success of Weaning in Mechanically Ventilated Newborns - A Randomized Controlled Trial - NIL | CTRI/2025/01/079530 |
| Caffeine for Hypoxic Ischemic Encephalopathy | Caffeine for Hypoxic Ischemic Encephalopathy (CHIME Trial) | NCT06855108 |
| Determining the effect of caffeine on the duration of seizures and the severity of psychotic symptoms in patients with schizophrenia undergoing electroshock treatment in Baharan Psychiatric Hospital in 2024: a randomized clinical trial study with placebo | Determining the effect of caffeine on the duration of seizures and the severity of psychotic symptoms in patients with schizophrenia undergoing electroshock treatment: a randomized clinical trial study with placebo | IRCT20250109064331N1 |
| Effect of Caffeine on respiratory muscle in premature newborns | Effect of Caffeine Citrate on diaphragmatic electrical activity in pre-term newborns | RBR-4x9j9hq |
| Effects of Caffeine on Reinforcement Learning in Healthy Adults Using PET/MRI | Measure Striatal Adenosine-dopamine Receptors Interactions: from Molecule to Behaviors | NCT06763172 |
| The bioequivalence of two commerical blackcurrant extracts and the effect of caffeine on the appearance of blackcurrant polyphenolics in blood plasma in healthy participants. | Investigating the polyphenol bioequivalence of a spray-dried blackcurrant powder with a commercial blackcurrant extract and determining the acute effect of caffeine on the polyphenol bioavailability when co-consumed with blackcurrant powder in healthy participants. | ACTRN12620001248954 |
| The effectiveness of L-theanine-caffeine combination given as a supplement compared to methylphenidate and placebo on improvement of selective attention in adolescents (age 10-19 years old) with attention-deficit hyperactive disorder: a double-blind, 3-way crossover trial | Acute effects of L-theanine and caffeine combination on selective attention in adolescents with attention deficit hyperactivity disorder | SLCTR/2023/004 |
| To Determine the Effect of KP-001 on Rosuvastatin, Caffeine PK and the Effect of Fluvoxamine on KP-001 PK in Volunteers | An Open-label Study to Determine the Effect of Oral Doses of KP-001 on Rosuvastatin and Caffeine PK After a Single Oral Administration and to Determine the Effect of Fluvoxamine on KP-001 PK After a Single Oral Administration in Volunteers | NCT06821698 |
| """Early Caffeine Discontinuation at 32 Weeks in Preterm Babies: Evaluating Apnea Recurrence at 32 vs. 34 Weeks The SAFE-CAFE Study""" | Safety Assessment for Early Caffeine Weaning: SAFE-CAFE PILOT Randomised Controlled Trial - SAFE - CAFE | CTRI/2025/02/080833 |
| Caffeine Vs. Carbohydrate Mouth Rinsing in Soccer | Caffeine Vs. Carbohydrate Mouth Rinsing in Soccer: Effects on Passing Performance and Psychophysiological Responses in Youth Players | NCT06881316 |
| Effects of Low-Dose Caffeine on Brainwave Activity and Cognitive Responses Following Fatigue in Taekwondo Athletes: A Randomized Controlled Study | Effects of Low-Dose Caffeine on Brainwave Activity and Cognitive Responses Following Fatigue in Taekwondo Athletes: A Randomized Controlled Study | TCTR20250319009 |
| The influence of prior information on the effect of caffeine on reaction time of university students | The influence of caffeine on the reaction time of university students | RBR-108r7p2n |
| EFFECTIVENESS OF CAFFEINE EYE CREAM ON PERIORBITAL WRINKLES | EFFECTIVENESS OF CAFFEINE EYE CREAM ON PERIORBITAL WRINKLES : Randomized double-blind placebo-controlled split-face trial | TCTR20250325001 |
| Setting of appropriate dosage and comparing the effectiveness of Caffeine and Aminophylline in premature babies with pause of breathing for 15 to 20 seconds | Population Pharmacokinetic and Pharmacodynamic study of Aminophylline and Caffeine in premature newborns with Apnea | CTRI/2015/06/005904 |
| A Study to Evaluate the Drug-Drug Interaction of EDP-323 With Midazolam, Caffeine, and Rosuvastatin in Healthy Participants | A Non-Randomized, Multiple-Dose, Open-Label, Single Sequence Study to Evaluate the Effect of Concomitant Administration of EDP-323 on the Pharmacokinetics and Safety of Midazolam, Caffeine, and Rosuvastatin in Healthy Participants | NCT06917508 |
| Acute Effects of Beetroot Juice and Caffeine Co-ingestion on Lower-limb Strength and Muscular Endurance in Females | Effect of Beetroot Juice Supplements with Caffeine Co-ingestion on Lower-limb Strength in Females | NCT06758323 |
| Effect of Oral Caffeine on Fatigue in Multiple Sclerosis Patients | The Effects of Oral Caffeine on Fatigue in Multiple Sclerosis Patients: A Randomized Double Blind Clinical Trial | IRCT20241129063892N1 |
| Caffeine and Resistance Training in Young Adults | Effects of Acute and Prolonged Caffeine Intake on Neuromuscular Adaptations to Resistance Training in Young Adults | NCT06610136 |
| Caffeine, CYPA12 and Resistance Exercise | Influence of CYP1A2 on the Acute Effect of Caffeine Intake on Resistance Exercise | NCT06610110 |
| Caffeine, Resistance Exercise and EMG | Effect of Acute Caffeine Intake on Muscle Electrical Activity and Muscular Strength, Power, and Endurance Performance | NCT06606652 |
| The Effects of Nitrate, Caffeine, and Cold Exposure on Cardiovascular Function. | Does Dietary Nitrate Supplementation Attenuate the Cardiovascular Strain Elicited by Caffeine and Cold Exposure in Healthy Individuals? | NCT06602921 |
| Caffeine Supplementation on Movement Patterns and Reactive Agility in Rugby Sevens Matches | Effect of Caffeine Supplementation on Movement Patterns and Reactive Agility in Rugby Sevens Matches | NCT06612463 |
| Caffeine can decrease the oxygen therapy in preterm: a randomised control trial | Caffeine to decrease the oxygen support duration in moderate and late preterm a randomised control trial - NIL | CTRI/2024/09/074203 |
| A Clinical Study to Evaluate The Efficacy of MA2/24 in Comparison with Caffeine on Mood, Energy, Focus,Attention and Fatigue in Healthy Working-Class Subjects. | A Prospective, Randomized, Double-Blind, 4-Arm, Parallel Group, Active-Controlled Study to Evaluate The Efficacy of MA2/24 in Comparison with Caffeine on Mood, Energy, Focus,Attention and Fatigue in Healthy Working-Class Subjects. - Nil | CTRI/2024/09/074472 |
| Evaluating the safety and effectiveness of minoxidil (5%) with procapil, redensyl, caffeine & transcutol vs plain minoxidil (5%) in androgenetic alopecia | An open-label prospective multicentric real-world evidence study to evaluate the safety and effectiveness of minoxidil (5%) with a combination of procapil, redensyl, caffeine, and transcutol vs plain minoxidil (5%) topical solution in study subjects with androgenetic alopecia | ISRCTN65325698 |
| Study to compare higher dose of a drug called caffeine citrate for managing a condition occuring in newborn babies called apnea of prematurity which invloves improving breathing control. | A randomized control study comparing two doses of caffeine for apnea of prematurity in tertiary care center. - NIL | CTRI/2024/10/074667 |
| Two maintenance doses of 5 and 10 mg caffeine citrate on the patent ductus arteriosus (PDA) in very low birth weight infants | The comparison of two maintenance doses of 5 and 10 mg caffeine citrate on the frequency of patent ductus arteriosus (PDA) in very low birth weight infants | IRCT20240929063204N1 |
| Investigation of the Effects of Oral Caffeine and Medroxyprogesterone on Improving Respiratory Function | Comparing the Effects of Oral Caffeine and Medroxyprogesterone on Improving Respiratory Function in Traumatic Brain Injury Patients Under Mechanical Ventilation | IRCT20181028041484N2 |
| Clinical study of ITCs caffeine powder | A Randomized, Double-Blind, Parallel, Placebo-Controlled Study of ITCs oral solid dose caffeine granules for the clinical evaluation of its efficacy as an instantaneous stimulant & overall energy and mood booster. - NIL | CTRI/2024/11/076424 |
| Caffeine Ingestion to Counter the Exercise-mediated Fall in Glycaemia in Type 1 Diabetes | Does Combined Caffeine and Carbohydrate Ingestion Counter the Exercise-mediated Fall in Glycaemia in Individuals With Type 1 Diabetes on Insulin Degludec? The DE-CAF Study | NCT04671043 |
| Caffeine Mouth Rinse on Salivary Immunoglobulin A, Lactoferrin and A-Amylase Levels | The Effect of Incremental Exercise After Caffeine Mouth Rinse on Salivary Immunoglobulin A, Lactoferrin and A-Amylase Levels | NCT06704711 |
| The Effect of Coffee on People with High Intensity Exercise and the Characteristics of Caffeine Metabolism | The Effect of Coffee on People with High Intensity Exercise and the Characteristics of Caffeine Metabolism | NCT06712667 |
| The Effect of Coffee on Energy Expenditure and Caffeine Metabolism | The Effect of Coffee on Energy Expenditure and Caffeine Metabolism | NCT06712511 |
| Influence of Caffeine on Psychomotor Vigilance and Carbon Dioxide Tolerance During Graded Hypercapnia | Influence of Caffeine on Psychomotor Vigilance and Carbon Dioxide Tolerance During Graded Hypercapnia | NCT06636825 |
| The Effect of BI 187004 on the Pharmacokinetics of Cytochrome P450 Substrates (Caffeine, Warfarin, Omeprazole, Metoprolol and Midazolam) and a P Glycoprotein Substrate (Digoxin) | The Effect of Multiple Doses of BI 187004 on the Single Dose Pharmacokinetics of Cytochrome P450 Substrates (Caffeine, Warfarin, Omeprazole, Metoprolol and Midazolam) and a P-glycoprotein Substrate (Digoxin) Administered Orally in an Open-label, One-sequence Trial in Healthy Subjects | NCT02254148 |
| Efficacy and Safety of Caffeine Citrate in the Treatment of GNAO1 Gene-Related Neurological Disorders in Children: A Prospective Cohort Study | Efficacy and Safety of Caffeine Citrate in the Treatment of GNAO1 Gene-Related Neurological Disorders in Children: A Prospective Cohort Study | ChiCTR2500100726 |
| Impact of caffeine intake on mental, cognitive and affective health during a strength training session | Evaluation of the effect of acute caffeine Supplementation on affective parameters, cognition, anxiety and mood during a strength training session in an adult population | RBR-7v86hk9 |
| Influence of a Bitter Compound and Bittermasking Compound on Gastric pH | Effect of Caffeine With and Without a Bitter Masking Compound on Gastric pH, Taking Into Account the Effect on Satiety Hormones in Blood Plasma and on Food Intake | NCT02372188 |
| Study to Evaluate the Effect of Multiple Doses of BIRT 2584 XX Tablets on the Pharmacokinetic Parameters of Warfarin, Omeprazole, Caffeine, and Dextromethorphan in Healthy Male Volunteers | A Study to Evaluate the Effect of Multiple Doses of 500 mg of BIRT 2584 XX Tablets on the Pharmacokinetic Parameters of Warfarin, Omeprazole, Caffeine, and Dextromethorphan Dosed Orally and Midazolam Dosed IV, in Healthy Male Volunteers | NCT02256813 |
| Acute effects of a single dose of L-theanine and caffeine combination compared to a placebo on reaction time, and brain activity underlying selective attention in acutely sleep-deprived healthy adults. | Acute effects of a single dose of L-theanine and caffeine combination on selective attention in acutely sleep-deprived healthy adults | SLCTR/2023/006 |
| Effects of an Acute Dose of Caffeine on the Performance of CrossFit Athletes | Effects of an Acute High Dose of Caffeine on Physiological Responses and Performance During a Strength-Focused CrossFit® Workout: a Randomized, Double - Blinded, Crossover Study | NCT06891469 |
| Caffeine-mediated modulation of human experimental pain models | Caffeine-mediated modulation of human experimental pain models | EUCTR2005-000408-16-SE |
| Caffeine in Children With Obstructive Sleep Apnea, Dose Response Study | Caffeine in Children With Obstructive Sleep Apnea, Dose Response Study | NCT01349205 |
| Caffeine in the Second Stage of Labor in Low-risk Nulliparous Mothers at Term | Caffeine in the Second Stage: A Randomized Control Trial in Low-risk Nulliparous Mothers at Term | NCT05906303 |
| Comparison of analgesic effect of Acetaminophen and Acetaminophen Codeine with caffeine in control of control preapical periodontitis pain | Comparison of analgesic effect of Acetaminophen and Acetaminophen Codeine with caffeine in control of control preapical periodontitis pain | IRCT201304121760N22 |
| Effects of L-theanine and Caffeine on Attention and Attention-related Brain Activity of Children With Attention Deficit Hyperactivity Disorder | Effects of L-theanine and Caffeine on Attention and Attention-related Brain Activity of Male Children and Adolescents With Attention Deficit Hyperactivity Disorder: a proof-of- Concept fMRI Study. | NCT03533556 |
| Clinical Trial on the Effects of Caffeine and Taurine From Energy Drinks (EDs) to Parameters of the Cardiovascular System in Humans | | NCT01421979 |
| Effect of Different Dosages of Paraxanthine, the Major Caffeine Metabolite, on Energy and Focus | Effect of Different Dosages of Paraxanthine, the Major Caffeine Metabolite, on Energy and Focus: A Randomized, Double-Blind, Placebo-Controlled, Crossover Trial | NCT06117280 |
| Effects of Concomitant Administration of BMS-986195 on Methotrexate, Caffeine, Montelukast, Flurbiprofen, Omeprazole, Midazolam, Digoxin, and Pravastatin | Effects of Concomitant Administration of BMS-986195 on the Single-dose Pharmacokinetics of Methotrexate and Probe Substrates for Cytochrome P450 1A2, 2C8, 2C9, 2C19, 3A4, Organic Anion Transporter Polypeptide 1B1 and P-glycoprotein in Healthy Participants | NCT03131973 |
| Clinical trial on paraxanthine (PX) in comparison to that of caffeine (CF) in otherwise healthy volunteers | A prospective, double-blind, randomized, cross-over, four arm, four treatments, two period, placebo-controlled study to evaluate the taste, memory/cognition and anxiety effects of 2 different doses of paraxanthine (PX) in comparison to that of caffeine (CF) in otherwise healthy volunteers | CTRI/2022/03/041219 |
| Effects of Caffeine, L-Theanine, and Diaphragmatic Breathing on Esports Players' Performance | Can L-Theanine Supplementation or Diaphragmatic Breathing Exercises in Addition to Caffeine Supplementation Be Used as Ergogenic Aids to Influence Game Performance in Esports Players? | NCT06621797 |
| Does caffeine consumption influence visual performance? | Effect of caffeine on a visual contrast perception task in young healthy adults | ACTRN12616000423415 |
| Evaluation of the pharmacokinetics of caffeine, baicalin, baicalein, and sulfasalazine after oral administration | Evaluation of the pharmacokinetics of caffeine, baicalin, baicalein, and sulfasalazine after oral administration | DRKS00031821 |
| How caffeine affects the visual brain | Effect of caffeine on visual neuroplasticity in young healthy adults | ACTRN12620000352909 |
| The Effect of Tablet Size on Cognitive Performance Caffeine | The Effect of Tablet Size on Cognitive Performance: A Randomized Control Trial Using Caffeine | NCT03694886 |
| Evaluation of Pharmacokinetic Interaction Between GSK3640254 and Caffeine, Metoprolol, Montelukast, Flurbiprofen, Omeprazole, Midazolam, Digoxin, and Pravastatin in Healthy Adults | Effects of GSK3640254 on the Single-Dose Pharmacokinetics of Probe Substrates (Caffeine, Metoprolol, Montelukast, Flurbiprofen, Omeprazole, Midazolam, Digoxin, and Pravastatin) in Healthy Subjects | NCT04425902 |
| To study the effects of caffeine and a glucose-caffeine combination on psychomotor performance | To study the effects of caffeine and a glucose-caffeine combination on psychomotor performance among students and staffs of Government Medical College and Research Institute in Bangalore. - nil | CTRI/2025/04/084768 |
| CAffeine Use in Prolonged Oxygen Use in meConium aspIration Syndrome in Neonatal Outcomes (CAPUCINO) | Caffeine for Oxygen Dependent Meconium Aspiration Syndrome | NCT06972108 |
| Caffeine Citrate to Improve Neonatal Outcomes. | BabyCCINO: Caffeine Citrate to Improve Neonatal Outcomes. A Neonatal Domain Within PLATIPUS. | NCT06972849 |
| Evaluation of Caffeine and Sodium Bicarbonate in Athletes | Evaluation of the Effects of Caffeine and Sodium Bicarbonate in Athletes | RBR-7qbb4bf |
| Effect of Caffeine on Cold-stimulated Brown Adipose Tissue Activity | Effect of Caffeine on Cold-stimulated Brown Adipose Tissue Activity | NCT06978777 |
| A Study to Investigate How Multiple Oral Doses of AZD2389 Affect the Pharmacokinetics of Midazolam, Caffeine, and Bupropion in Healthy Participants | An Open-label, Fixed Sequence Study in Healthy Participants to Assess the Effect of Multiple Doses of AZD2389 on the Pharmacokinetics of Midazolam, Caffeine, and Bupropion | NCT06973005 |
| Evaluation of the Efficacy of Caffeine in Reducing the Duration of Respiratory Support in Preterm Neonates | Efficacy of Oral Caffeine on Duration of Respiratory Support in PretermNeonates Weighing 1250 to 2000 gram: A Randomized Controlled Trial - CURE-N | CTRI/2025/05/087145 |
| study for optimizing appropriate dosage of Caffeine and Aminophylline in premature new born babies with pause of breathing lasting atleast for 20 seconds | Population Pharmacokinetic and Pharmacodynamic study of Caffeine and Aminophylline in Apnea of prematurity - AOP, PKPD, AGA, SGA | CTRI/2017/10/010132 |
| Hand Reaction Speed and Manual Dexterity & Caffeine Dependence | Investigation of Hand Reaction Speed and Manual Dexterity in Young Adults With Caffeine Dependence | NCT07032454 |
| Effect of Caffeine Supplementation Compared to Placebo on Liver Fat Content and Scarring in Adults with Fatty Liver Disease: A Randomized Controlled Trial. | Randomized ,Quadruple-blind, Placebo-controlled, Clinical Trial to determine the effects of Coffee (caffeine) supplementation on Hepatic Steatosis and Fibrosis in Metabolic dysfunction-associated Steatotic Liver Disease(MASLD). | SLCTR/2025/023 |
| An Open Label, Single Dose, Three Part Study to Assess the Effects of Rolapitant (2 mg/mL IV Solution) on the Pharmacokinetics of Digoxin; Sulfasalazine; and the Cooperstown Cocktail (Midazolam, Omeprazole, Warfarin, Caffeine, and Dextromethorphan in Healthy Subjects | An Open Label, Single Dose, Three Part Study to Assess the Effects of Rolapitant (1.8 mg/mL Rolapitant IV Solution) on the Pharmacokinetics of Digoxin (P-gp); Sulfasalazine (BCRP); and the Cooperstown Cocktail (Midazolam [CYP3A4], Omeprazole [CYP2C19], Warfarin [CYP2C9], Caffeine [CYP1A2], and Dextromethorphan [CYP2D6]) in Healthy Subjects | NCT02434861 |
| A study to determine bioavailability and safety of ND 10 (7 Methylxanthine a caffeine derivative)Extended Release Tablets 500 mg | An open label balanced randomized two-treatment two-period two-sequence multiple-dose steady state crossover comparative bioavailability study of ND 10 (7-Methylxanthine, a caffeine derivative) Extended-Release Tablets 500 mg of Theialife Sciences comparing with ND 10 (7-Methylxanthine a caffeine derivative) Immediate Release Tablets 400 mg of Theialife Sciences in healthy adult human subjects under fed conditions - NA | CTRI/2024/02/062928 |
| A study to determine the absorption and safety of ND 10 (7 Methylxanthine a caffeine derivative) Extended Release Tablets 500 mg | An open label single treatment single period single strength twice daily dosing bioavailability study of ND 10 (7 Methylxanthine a caffeine derivative) Extended Release Tablets 500 mg of Theialife Sciences in healthy adult human subjects under fed conditions - NA | CTRI/2024/02/062927 |
| Celecoxib vs. Acetaminophen/Codeine/Caffeine for Post-operative Analgesia in Rhinoplasty. | Celecoxib vs. Acetaminophen-codeine-caffeine for Postoperative Pain in Primary Elective Open Septorhinoplasty With Osteotomies: a Randomized Controlled Trial. | NCT04259333 |
| Preoperative Acetaminophen- Caffeine- Codeine Combination and Anaesthetic Success in Patients With Acute Pulpitis | Effect of Preoperative Acetaminophen-Codeine-Caffeine Combination on Inferior Alveolar Nerve Block Success in Patients With Symptomatic Irreversible Pulpitis: Randomized Double-blind Controlled Trial | NCT04202406 |
| A study to determine bioavailability and safety of ND 10 (7 Methylxanthine a caffeine derivative)Extended Release Tablets 500 mg | An open label, balanced, randomized, two-treatment, two-period, two-sequence, single-dose,crossover, comparative bioavailability study of ND 10 (7-Methylxanthine, a caffeine derivative)Extended-Release Tablets 500 mg of Theialife Holdings Limited comparing with ND 10 (7-Methylxanthine, a caffeine derivative) Immediate Release Tablets 400 mg of Theialife HoldingsLimited in healthy, adult, human subjects under fasting condition. - NIL | CTRI/2025/04/084974 |
| Pharmacokinetic and Safety Study of Cenicriviroc and HMG-CoA Reductase Inhibitors, Caffeine and Digoxin | A Phase 1 Open-Label Study in Healthy Adult Subjects to Assess the Effect of Cenicriviroc Mesylate (CVC) on the Pharmacokinetics (PK) of HMG-CoA Reductase Inhibitors (Rosuvastatin, Atorvastatin and Simvastatin), Caffeine and Digoxin | NCT02685462 |
| Pharmacokinetic Drug-Drug Interaction Study of Rucaparib | A Phase 1, Open-label, Multiple-probe Drug-drug Interaction Study to Determine the Effect of Rucaparib on Pharmacokinetics of Caffeine, S-Warfarin, Omeprazole, Midazolam, and Digoxin in Patients With Advanced Solid Tumors | NCT02740712 |
| Caffeine and Resistance Training in Older Adults | Effects of Acute and Prolonged Caffeine Intake on Neuromuscular Adaptations to Resistance Training in Older Adults | NCT06618261 |
| Carbohydrate Rinsing and Caffeine Gum on Performance of Romanian Deadlifts Performance | Carbohydrate Mouth Rinses and Caffeine Gum Increase the Romanian Deadlift Performance on the Flywheel Training Device: A Randomised, Cross-Over Study | NCT05900349 |
| Caffeine, CYPA12 and Resistance Training | Influence of CYP1A2 on the Prolonged Effect of Caffeine Intake on Resistance Training | NCT06610123 |
| Effect of Acute Caffeine and Beetroot Juice Intake on Strength, Power, and Muscular Endurance | Effect of Acute Caffeine and Beetroot Juice Intake on Strength, Power, and Muscular Endurance Based on Circadian Rhythms. | NCT06596395 |
| Comparison of a triple therapy versus monotherapy in patients with acute mechanical low back and/or cervical pain | Combined nonsteroidal anti-inflammatory drug, muscle relaxant, and caffeine versus nonsteroidal anti-inflammatory drug or mucle relaxant monotherapy for acute mechanical low back and/or cervical pain. A double blind, randomized, multicenter, phase III study. | IRCT138807012498N1 |
| Effects of Caffeine Ingestion on the Biomechanics of Healthy Young Subjects | Influence of 6mg/kg of Caffeine Supplementation on the Technical Execution of General Movement Patterns Performed by Healthy Subjects, With and Without Neuromuscular Fatigue: a Randomized, Double-blind, Placebo-controlled, Crossover Trial | NCT06039358 |
| The effect of caffeine on anaerobic performance and fatigue caused by it | The effect of different doses of caffeine consumption on EMG activity variables and muscle fatigue index in response to maximal anaerobic test in healthy women | IRCT20230622058558N1 |
| A clinical trial to evaluate duration of caffeine therapy for apnea of prematurity in preterm newborn. | Proportion of recurrence of Clinically Significant Apnea among neonates of gestational age 28 to 32 weeks on stopping Caffeine after an apnea free periods of 7 days :A Prospective Observational Study. - nil | CTRI/2023/09/057347 |
| The Turkish Version Of The Brief-Caffeine Expectancy Questionnaire | Evaluation of The Psychometric Properties of The Turkish Version of The Brief-Caffeine Expectancy Questionnaire (B-CaffeQ): An Adaptation Study in Recreationally Active Individuals | NCT06038903 |
| Comparison of two caffeine therapy protocols in premature babies | “Symptom based ? compared to “current consensus based ? duration of caffeine therapy in neonates (26-31 weeks of gestation) for apnoea of prematurity: A non-inferiority randomized controlled trial - NIL | CTRI/2023/09/057692 |
| Effect of increasing caffeine intake compared to usual maintenance dose in preterm neonates: A Randomised Controlled Trial | Effect of escalating versus standard maintenance dose of caffeine in preterm neonates: A Randomized Controlled Trial - nil | CTRI/2023/09/057903 |
| Caffeine as an Adjuvant Therapy for Late Preterm Infants With Respiratory Distress | Caffeine for Late Preterm Infants: A Double Blind Randomized Controlled Trial | NCT06026163 |
| Effect of Strength Versus Endurance Training on Muscle Damage in Gym Athletes on Caffeine Supplementation. | Effect of Strength Versus Endurance Training on Muscle Damage in Gym Athletes on Caffeine Supplementation. | NCT06086691 |
| Investigating the effect of onion extract and rosemary essential oil and caffeine on reducing hair loss in patients with androgenetic alopecia | Investigating the effect of a product containing onion extract, rosemary essential oil and caffeine on reducing hair loss in patients with mild to moderate androgenetic alopecia | IRCT20150221021159N9 |
| Comparison of different doses of caffeine (respiratory stimulant) to prevent intermittent episodes of cessation of breathing and low saturation/heart rate in preterm babies | High (10mg/kg/day) vs. Standard maintenance dose (5mg/kg/day) of caffeine on the incidence of caffeine therapy failure in preterm infants of less than 32 weeks gestational age: An open label, parallel group, superiority randomized controlled trial - NIL | CTRI/2023/10/058930 |
| Comparing the efficacy of 0.025% Fluocinolone acetonide with and without 5% caffeine in topical treatment of chronic plaque psoriasis | Efficacy of 5% caffeine plus 0.025% Fluocinolone acetonide versus 0.025% Fluocinolone acetonide alone for topical treatment of chronic plaque psoriasis | IRCT20091012002581N10 |
| The effect of exercise and caffeine on health and performance indicators | The effect of eight weeks of spinning training and caffeine supplementation on lipid profile, body composition and functional fitness of overweight women | IRCT20220906055902N1 |
| Effect of HIT and caffeine supplementation on exercise performance and adaptations | The effect of high-intensity interval training and caffeine supplementation on exercise adaptations and ergogenicity of acute caffeine intake in young men | IRCT20231004059615N1 |
| The preoperative oral caffeine for the prophylaxis against spinal anesthesia induced hypotension in patients undergoing orthopedic lower limb surgery: A randomized controlled study | The preoperative oral caffeine for the prophylaxis against spinal anesthesia induced hypotension in patients undergoing orthopedic lower limb surgery: A randomized controlled study | PACTR202311786558285 |
| Neurobehavioral Correlates of Caffeine on Anxiety, Avoidance and Interoception in Healthy Individuals and Panic Disorder. | Adenosine Receptors from Genes to Behavior: Neurobehavioral Correlates of Caffeine on Anxiety, Avoidance, Decision-Making and Interoception in Healthy Individuals and Panic Disorder. | NCT06145490 |
| the Incidence of Necrotizing Enterocolitis in Preterm With Respiratory Distress Syndrome Undergoing Caffeine Therapy | Evaluation of the Incidence of Necrotizing Enterocolitis in Preterm Infants With Respiratory Distress Syndrome Undergoing Caffeine Therapy | NCT06097767 |
| Are Aminophylline and Caffeine equally effective in preventing long term lung problems in premature babies? | Early Aminophylline versus Caffeine in Very Preterm Neonates and Neonatal Chronic Lung Disease - a randomized controlled, non-inferiority trial - AminoCaP-BPD | CTRI/2023/11/060258 |
| In vivo evaluation of press-coated tablets with caffeine for the determination of gastric water emptying in fasted and fed state and the influence of MEDCOAT® | In vivo evaluation of press-coated tablets with caffeine for the determination of gastric water emptying in fasted and fed state and the influence of MEDCOAT® - kinetic press-coated tablets | DRKS00032457 |
| Effects Of Caffeine On Cognitive Performance | Effects Of Different Doses Of Caffeine On Cognitive Performance In Healthy Physically Active Individuals | NCT05995314 |
| Effects of Caffeine on Cerebral Blood Flow | Effects of Caffeine on Cerebral Blood Flow in Clinically Healthy Young People | NCT05866848 |
| Comparison of the effectiveness of maintenance doses of caffeine citrate on tracheal tube removal and apnea after it in premature infants | Comparison of the effectiveness of maintenance doses of caffeine citrate on tracheal tube removal and apnea after it in premature infants | IRCT20230408057850N1 |
| Fasciculations in Healthy Adults After Consumption of Caffeine: an Ultrasound Study | Fasciculations in Healthy Adults After Consumption of Caffeine: an Ultrasound Study | NCT05977920 |
| Effects of Caffeine on Upper Extremity Performance | The Effect of Caffeine Supplementation on Blood Lactate Level, Performance and Post-Training Fatigue in Elite Basketball Players | NCT05916352 |
| Caffeine versus Dexmedetomidine for the prevention of emergence delirium in children undergoing lower abdominal surgery with sevoflurane anesthesia: a randomized, double-blind, controlled study | Caffeine or Dexmedetomidine for the prevention of emergence delirium in children undergoing lower abdominal surgery with sevoflurane anesthesia: a randomized, double-blind, controlled study | PACTR202306816155472 |
| Effects of Acute Intake of Caffeinated Beverages in Type 1 Diabetes | Effects of Acute Intake of Caffeine Enhanced Energy Drinks on Blood Glucose, Some Physiological Parameters and Cognitive Performance in Patients With Type 1 Diabetes | NCT01805700 |
| Study of Caffeine in the Attention and Memory of Women with Premenstrual Tension | Study of Caffeine Abstinence on Cognitive Parameters in women of childbearing age with Premenstrual Syndrome | RBR-9w9pw9q |
| A Randomized Study to Examine the Ability of a Caffeine-Based Energy Drink to Impact Energy Expenditure, Fat Oxidation, Reaction Time, and Other Perceptual Indicators | A Randomized Study to Examine the Ability of a Caffeine-Based Energy Drink to Impact Energy Expenditure, Fat Oxidation, Reaction Time, and Other Perceptual Indicators | NCT05998096 |
| A Study to Assess the Effect of BMS-986419 on the Single Dose Drug Levels of Probe Substrates in Healthy Participants | A Phase 1 Open-label Study to Assess the Effect of BMS-986419 on the Single Dose Pharmacokinetics of Probe Substrates (Caffeine, Bupropion, Flurbiprofen, Omeprazole, Midazolam, and Fexofenadine) in Healthy Participants | NCT05932277 |
| Ergogenic effects of the combination of caffeine and New Zealand blackcurrant supplements: A double-blind singe-case experimental study | Ergogenic effects of the combination of caffeine and New Zealand blackcurrant supplements: A double-blind singe-case experimental study - CAF + NZBC | DRKS00032109 |
| Clinical analysis of caffeine citrate at different time to prevent bronchopulmonary dysplasia in very low birth weight infants | Clinical analysis of caffeine citrate at different time to prevent bronchopulmonary dysplasia in very low birth weight infants | ChiCTR2300073516 |
| To determine if apnea episodes(cessation of breathing in premature newborns) occur less frequently in infants whose caffeine(drug used for treatment of apnea) doses are increased for weight gain | WEIGHT-BASED DOSE ADJUSTMENT OF CAFFEINE CITRATE VERSUS FIXED DOSE CAFFEINE CITRATE FOR THE TREATMENT OF NEONATES WITH APNEA OF PREMATURITY: A RANDOMISED CONTROL TRIAL | CTRI/2023/07/055443 |
| Genetics in the Effect of Caffeine on Fat Oxidation | Influence of the Genetic Polymorphisms in the Effect of Caffeine on Fat Oxidation During Exercise | NCT05975489 |
| Investigating the effect of caffeine on cognitive and motor responses | Effects of brushing with caffeinated toothpaste on cognitive and motor responses of the central nervous system: A pilot study | IRCT20230318057752N2 |
| Comparison of postoperative analgesic effect of intravenous acetaminophen versus intravenous caffeine in distal radius surgery | Comparison of postoperative analgesic effect of intravenous acetaminophen versus intravenous caffeine in distal radius surgery | IRCT20230716058807N1 |
| Effect of Caffeine for fast-track surgery and cognitive functions in children undergoing open heart surgery: a randomized, double-blind, controlled study. | Caffeine for fast-track pediatric cardiac anesthesia in children undergoing open heart surgeries: a randomized, double-blind, controlled study. | PACTR202308786657562 |
| Caffeine/Glucose and Multi-tasking | An investigation into the effects of two doses of glucose alone and a single dose of caffeine-glucose in combination on cognitive performance, fatigue and mood associated with extended multi-tasking in healthy adults aged 18-55 years | ACTRN12613000247774 |
| Caffeine vs. ALA in BMS Treatment. (BMS: Burning Mouth Syndrome. ALA: Alpha-Lipoic Acid.) | Efficacy of Caffeine vs. Alpha-Lipoic Acid in Burning Mouth Syndrome Treatment | NCT06195137 |
| Exercise-Induced Rates of Fat Oxidation with and Without Ingestion of a Caffeine-Based Energy Drink | A Crossover Study to Examine Exercise-Induced Rates of Fat Oxidation with and Without Ingestion of a Caffeine-Based Energy Drink | NCT06308731 |
| Baby-CINO: CaffeINe Treatment Optimisation in Premature Infants | Baby-CINO: CaffeINe Treatment Optimisation in Premature Infants | NCT06416956 |
| Dose Optimization of Caffeine for HIE | Dose Optimization of Caffeine in Neonates With Hypoxic-Ischemic Encephalopathy | NCT06448780 |
| Evaluation of gastric water emptying in fasted and fed state inyoung and advanced age populations with the use of a press-coated tablet containing caffeine | Evaluation of gastric water emptying in fasted and fed state inyoung and advanced age populations with the use of a press-coated tablet containing caffeine - Saliva_AgePop_fasted&fed | DRKS00033548 |
| The short-term effect of caffeine supplement on changes in myocardial oxygen consumption, heart rate variability, Delayed-Onset Muscle Soreness (DOMS) and rating of perceived exertion in trained young men | The short-term effect of caffeine supplement on changes in myocardial oxygen consumption, heart rate variability, Delayed-Onset Muscle Soreness (DOMS) and rating of perceived exertion in trained young men | IRCT20240521061865N1 |
| A study to test whether BI 456906 (survodutide) influences the amount of bupropion, caffeine and midazolam in the blood in people with overweight or obesity | - 1404-0008 | CTIS2024-512332-29-00 |
| Comparison of the salivary kinetics of caffeine, theacrine and methylliberin after oral application in the fasted state | Comparison of the salivary kinetics of caffeine, theacrine and methylliberin after oral application in the fasted state - Saliva_Uricacid_fasted | DRKS00033549 |
| Caffeine Citrate in Preterm Infants at Risk of Apnea in Zambia | Randomized Controlled Trial of Caffeine Citrate in Preterm Infants at Risk of Apnea in Zambia | NCT06518603 |
| Effect of caffeine in premature infants | The rate of osteopenia of prematurity in premature infants who received caffeine prophylaxis in the neonatal intensive care unit: a clinical trial | IRCT20230914059430N2 |
| Acute Effects of PLT Health Solutions zu¨mXR Extended-Release Caffeine | The Acute Effects of PLT Health Solutions zu¨mXR Extended-Release Caffeine on Side Effects, Mood and Alertness Following a Night of Suboptimal Sleep | NCT06441695 |
| Caffeine pills in the prevention of postoperative delirium | Comparison of the effect of oral caffeine pills compared to placebo in the prevention of postoprative delirium in surgical patients admitted to intensive care unit. | IRCT20210523051374N1 |
| CYP1A2 and ADORA2A Genotypes and Endurance Performance. | Effects of Caffeine, CYP1A2 and ADORA2A Genotypes on Cycling Endurance Performance. | NCT06547307 |
| Comparaing effects of different doses of caffeine mouth rinsing doses on physical and cognitive performance of athletes | Comparative analysis of caffeine mouth rinsing doses on physical performance variables and cognitive function of athletes - NIL | CTRI/2024/08/071847 |
| In vivo evaluation of hard gelatin and hypromellose capsule disintegration in fasted state after intake with different fluids by salivary caffeine method | In vivo evaluation of hard gelatin and hypromellose capsule disintegration in fasted state after intake with different fluids by salivary caffeine method | DRKS00033547 |
| A Study to Evaluate the Effect of EnXtra® and EnXtra® + Caffeine on Mental Alertness and Fatigue in Healthy Individuals | A Randomized, Double-blind, Placebo-controlled Study to Evaluate the Effect of EnXtra® and EnXtra® + Caffeine on Mental Alertness and Fatigue in Healthy Individuals | NCT06560008 |
| Investigating the effect of rosemary essential oil and caffeine on reducing hair loss in patients with androgenetic alopecia | Investigating the effect of a product containing caffeine and rosemary essential oil (Rosmarinus officinalis) on reducing hair loss in patients with mild to moderate androgenetic alopecia | IRCT20150221021159N10 |
| Caffeine for protection from kidney failure in babies who do not breathe or cry at birth | Caffeine for the Prevention of Acute Kidney Injury in Neonates with Perinatal Asphyxia: A Randomized Controlled Trial - Nil | CTRI/2024/08/073008 |
| A Study to Evaluate the Effect of EnXtra® and EnXtra® + Caffeine on Mental Alertness and Fatigue in Healthy Individuals | A Randomized, Double-blind, Placebo-controlled Study to Evaluate the Effect of EnXtra® and EnXtra® plus Caffeine on Mental Alertness and Fatigue in Healthy Individuals - NIL | CTRI/2024/09/073338 |
| Dex +/- Caffeine Sedation in a Post-MRI Recovery in a Pediatric Population | Caffeine Facilitates the Recovery of Dexmedetomidine Sedation for MRI in Pediatric Patients: a Randomized, Double-blinded and Placebo-controlled Pilot Study | NCT06538584 |
| Effects of Caffeine-based Supplement on Physical Performance | Acute Effects of Multi-ingredient Pre-workout Dietary Supplement on Physical Performance in Untrained Men | NCT06363669 |
| Caffeine & Bodybuilding Dehydration Ability | Effect of Caffeinated Chewing Gum on Dehydration Ability in Bodybuilding Athletes: a Crossover Trial | NCT06431035 |
| Changes in body functions before and after intravenous caffeine in neonates with birth related brain injury | Physiological responses to intravenous caffeine in neonates with Hypoxic Ischaemic Encephalopathy. - NIL | CTRI/2024/04/065198 |
| Research on the causes and treatment of burning mouth syndrome | Study on the relieving effect of caffeine on clinical symptoms of burning mouth syndrome | ChiCTR2300078771 |
| Caffeine gel-cream in the treatment of Gynoid Lipodystrophy | Development and evaluation of a pharmaceutical system containing Caffeine for the treatment of Gynoid Lipodystrophy | RBR-10qpynpd |
| Caffeine and Training Intensity Quantification | The Effects of Caffeine Supplementation on Training Intensity Quantification | NCT06210984 |
| Motivational, Affective and Performance Effects of Caffeine Supplementation | The Effects of Caffeine Supplementation on Motivation, Affect and Performance in Physical Exercise Tests: An Intervention Study | NCT06321861 |
| Effect of Caffeine or Transcranial Direct Current Stimulation on attack decision-making in trained beach volleyball players after prolonged cognitive effort by use of social media: a study crossover randomized | Caffeine and Transcranial Direct Current Stimulation: effect on the performance of mentally fatigued young athletes | RBR-2yyd8jb |
| Effects of Caffeine Ingestion on Endurance Performance, Psychological state, and Oxidative Stress Status in Young Recreational Runners | Low-dose Caffeine Ingestion Improves Exhaustive Endurance Performance and does not Affect Oxidative Stress Markers in Young Recreational Runners | PACTR202402674777836 |
| Comparing Different Caffeine Amounts to Prevent Breathing Problems in Premature Babies: A Study (HI-CAF Trial) | Higher versus Standard Caffeine dosing in Prevention of Apnoea of Prematurity: A Randomized Controlled Trial(HI-CAF trial) - HI-CAF trial | CTRI/2024/03/063926 |
| Caffeine Use in the Management of Preterm Infants | Caffeine Use in the Management of Preterm Infants | NCT06327152 |
| Investigating the effect of caffeine and warming up in sprinters | Effects of adding total motion release technique to caffeine ingestion on neuromuscular, cognitive and anaerobic performance in male sprinters | IRCT20230708058720N1 |
| The Effect of an Additional Pre-extubational Loading Dose of Caffeine-citrate | The Effect of an Additional Pre-extubational Loading Dose of Caffeine-citrate | NCT06401083 |
| The effects of the combination of glucosyl-hesperidin and caffeine on serum triglyceride and visceral fat in human dose-finding study:Double-blind, placebo-controlled trial | The effects of the combination of glucosyl-hesperidin and caffeine on serum triglyceride and visceral fat in human dose-finding study:Double-blind, placebo-controlled trial - The effects of the combination of glucosyl-hesperidin and caffeine on serum triglyceride and visceral fat in human | JPRN-UMIN000019241 |
| Effects of caffeine and music on anaerobic exercise performance | Effects of caffeine intake combined with listening to self-selected music during warm-up on Wingate performance: a double-blind, randomized crossover study | ISRCTN10555501 |
| Early versus Conventional discontinuation of Caffeine therapy for premature babies with apnea | Early versus Conventional discontinuation of Caffeine therapy for Apnea of Prematurity- A Randomized Controlled Trial - NIL | CTRI/2024/03/064781 |
| Trial of the effects of caffeine intake timing on endurance performance: based on genotype | Impact of the Timing of Caffeine Ingestion on Endurance Exercise Performance Based on the CYP1A2 Genotype - Caffeine intake timing on endurance performance trial | JPRN-UMIN000054033 |
| Effect of Caffeine Consumption on Protein Biomarkers and Cardiovascular Disease | Feasibility Study for Investigating the Effect of Caffeine Consumption on Protein Biomarkers Related to Cardiovascular Disease | NCT06359197 |
| Effects of caffeine intake on body composition changes in obese people with intermittent fasting | Effects of caffeine intake on body composition changes in obese people with intermittent fasting | TCTR20240403003 |
| Investigating the effect of caffeine in increasing the level of consciousness of patients with benzodiazepine poisoning | Investigating the effect of caffeine in increasing the level of consciousness of patients with benzodiazepine poisoning who referred to Loghman Hakim Hospital in from March to June 2024 | IRCT20091116002717N2 |
| Reproducibility of Acute Caffeine Effect | Reproducibility of the Acute Effect of Caffeine on Energy Metabolism and Muscular Strength, Power and Endurance Performance | NCT06606639 |
| Caffeine for Apnea of Prematurity-Sleep (CAP-S) Study | Long-Term Effects On Sleep Of Methylxanthine Therapy For Apnea Of Prematurity | NCT01020357 |
| Caffeine for Excessive Daytime Somnolence in Parkinson's Disease | Caffeine for Excessive Daytime Somnolence in Parkinson's Disease | NCT00459420 |
| Quitting Caffeine for Better Glucose Metabolism | Quitting Caffeine for Better Glucose Metabolism | NCT01030796 |
| The Effects of Caffeine Withdrawal on Migraine | The Effects of Caffeine Withdrawal on Migraine - a Randomized, Double-blind, Crossover Study | NCT03022838 |
| Caffeine supplementation can make runners run further and improve pace strategy | Effects of creatine and caffeine supplementation association in street runners performance | RBR-5x8ttb |
| A clinical trial to evaluate the duration of caffeine therapy for apnea of prematurity | Comparison of two durations of caffeine therapy on clinically significant apnea - A randomized controlled trial. | CTRI/2016/12/007559 |
| To Evaluate the Superiority of Fixed Combination (Orfenadrine 35mg, Acetaminophen 325mg, Caffeine 65mg and Diclofenac Sodium 50mg) Compared to Voltaren® (Diclofenac Sodium 50mg) in the Treatment of Acute Postural Low Back Pain. | National Clinical Study, Phase III, Multicenter, Randomized, Double-blind, Controlled, Parallel, to Evaluate the Superiority of the Fixed Association (Orfenadrine 35mg, Acetaminophen 325mg, Caffeine 65mg and Diclofenac Sodium 50mg) Compared to the Drug Comparator Voltaren® (Diclofenac Sodium 50mg), in the Treatment of Acute Episode of Mechanical Postural Low Back Pain. | NCT02985671 |
| A Study of Caffeine on Cardiac Arrhythmias | A Prospective Placebo Controlled Randomized Study of Caffeine in Patients With Supraventricular Tachycardia Undergoing Electrophysiologic Testing. | NCT02095405 |
| Comparing The Prophylactic Effects of Caffeine versus Aminophylline on the Apnea of Prematurity in Neonates of Kabul City: A randomized clinical trial | Comparing The Prophylactic Effects of Caffeine versus Aminophylline on the Apnea of Prematurity in Neonates of Kabul City: A randomized clinical trial | DRKS00020404 |
| An evaluation of the drug interaction potential of extended-release felodipine in healthy volunteers, using a cocktail approach | An investigation of the proportional change in area under the concentration-time curves for five orally administered CYP P450 probes (caffeine, losartan, omeprazole, dextromethorphan, midazolam) and one Pgp probe (digoxin) when administered with and without steady-state oral felodipine, in twelve healthy adult volunteers. | ACTRN12611000811909 |
| How Does Altering the Timing of Pre-exercise Low-dose Caffeine Ingestion Affect Endurance Exercise Performance | How Does Altering the Timing of Pre-exercise Low-dose Caffeine Ingestion Affect Endurance Exercise Performance | NCT02985606 |
| Ibuprofen/Caffeine Lower Back or Neck Pain Study | A Randomized, Placebo- and Active-controlled Multi-country, Multi-centre Parallel Group Study to Evaluate the Efficacy and Safety of a Fixed Dose Combination of 400 mg Ibuprofen and 100 mg Caffeine Compared to Ibuprofen 400 mg and Placebo in Patients With Acute Lower Back or Neck Pain. | NCT03003000 |
| Effects of Caffeine on EEG Theta/Beta Ratio and Cognitive Control | The Effects of a Single Administration of a Moderate Dose of Caffeine on Cognitive Control and Spontaneous EEG Theta/Beta Ratio | NCT02940808 |
| Effects of Caffeine on Sleep-wake Regulation in Teenagers | Caffeine-induced Effects on Sleep, Cognitive Performance, and Underlying Cerebral Correlates During Adolescence - a Randomised, Placebo-controlled, Double-blind Clinical Study | NCT04321785 |
| Early caffeine administration prevents bronchopulmonary dysplasia of early preterm infants | Early caffeine administration prevents bronchopulmonary dysplasia of early preterm infants: a multiple RCT | ChiCTR-INR-16009243 |
| Effect of caffeine supplementation on physical performance and oxidative stress during high-intensity exercises | Effect of caffeine supplementation at physical performance and balance redox during a high-intensity interval training (HIIT) protocol | RBR-52twgg |
| Inhibition of VAP-1 by Caffeine in Healthy Human Volunteers Study | Phase I Clinical Trial Investigating the Effects of Caffeine Citrate on Serum Vascular Adhesion Protein -1 (VAP-1) Levels in Healthy Volunteers. | NCT02098785 |
| Caffeine, Catecholamines and Tremor | | ISRCTN54747943 |
| Early Caffeine in Preterm Neonates | A Randomized, Placebo-controlled Trial of Early Caffeine in Preterm Neonates | NCT03086473 |
| The Effect of a Caffeine Blend on Reaction Time, Mental Performance and Focus in Athletic Males | Effects Of A Proprietary Supplement On The Acute Responses In Reaction Time, Mental Performance, And Indicators Of Focus In Athletic Populations | NCT03019523 |
| The effect of aerobic training and caffeine consumption on quality of life and life expectancy in overweight men | The effect of aerobic training and caffeine consumption on quality of life and life expectancy in overweight men in Gachsaran | IRCT20200215046506N2 |
| Treatment for Caffeine Dependence | Treatment for Caffeine Dependence | NCT01951872 |
| Real-Time Caffeine Optimization During Total Sleep Deprivation | Real-Time Caffeine Optimization During Total Sleep Deprivation | NCT04399083 |
| Caffeine Study for Pain Control Following Total Joint Replacement | A Prospective Double Blinded Randomized Placebo Controlled Study of the Efficacy of Caffeine as an Analgesic Adjuvant for Acute Perioperative Pain Management Following Total Joint Arthroplasty | NCT04280263 |
| Investigation of the Effects of Diet on the Measurement of Plasma Chromogranin in NET Patients | Investigation of the Effects of Breakfast or Caffeine Containing Beverages on the Measurement of Plasma Chromogranin A in Patients With Gastro-entero-pancreatic Neuroendocrine Tumours (GEP-NET) | NCT03288402 |
| The Effects of Coffee Main Constituents (Caffeine and Chlorogenic Acid) Supplementation on Inflammatory, Metabolic Factors, Hepatic Steatosis and Fibrosis in None- Alcoholic Fatty Liver Patients With Type 2 Diabetes | | NCT02929901 |
| Comparative Study between Hydrocortisone and Caffeine in Treatment of Postdural Puncture Headache: A Randomized Double-Blind Study | Comparative Study between Hydrocortisone and Caffeine in Treatment of Postdural Puncture Headache: A Randomized Double-Blind Study | PACTR201708002484171 |
| Drug-drug Interaction Study Between EDP-305, Midazolam, Caffeine and Rosuvastatin in Healthy Volunteers. | A Non-Randomized, Multiple-Dose, Open-Label, Single Sequence Study to Evaluate the Effect of Concomitant Administration of EDP-305 on the Pharmacokinetics and Safety of Midazolam, Caffeine, and Rosuvastatin in Healthy Human Volunteers | NCT03187496 |
| Caffeine intake on post-caesaraean bowel movements | A Randomized controlled trial to evaluate the effect of postoperative caffeine intake on the return of bowel movements post caesarean section - NIL | CTRI/2024/07/071275 |
| Bioequivalence study of two oral fixed-dose combination tablets of 250 mg acetylsalicylic acid, 250 mg paracetamol and 65 mg caffeine in healthy volunteers after controlled fasting | Bioequivalence study of two oral fixed-dose combination tablets of 250 mg acetylsalicylic acid, 250 mg paracetamol and 65 mg caffeine in healthy volunteers after controlled fasting - P360 | DRKS00020899 |
| The effect of caffeine on neurorehabilitation after stroke | Evaluation of the effects of caffeine with or without transcranial magnetic stimulation on neurorehabilitation of motor impairments after stroke | IRCT2017021832625N1 |
| The effects of caffeine on walking and balance in patients with multiple sclerosis | Determine the effect of caffeine on the ability to walk and balance in patients with multiple sclerosis | IRCT2017012332142N1 |
| The effect of acetaminophen and caffeine on headache in cesarean section | Effect of acetaminophen and caffeine on post-Dural puncture headache in cesarean section | IRCT20141009019470N98 |
| Does Caffeine Enhance Bowel Recovery After Colorectal Surgery? | Does Caffeine Enhance Bowel Recovery After Colorectal Surgery? | NCT03097900 |
| Efficacy and Safety of Ibuprofen and Caffeine in Dental Pain | A Single-centre, Double-blind, Randomised, Two-stage, Parallel-group Study to Assess the Efficacy and Safety of the Fixed Dose Combination of Ibuprofen 400 mg and Caffeine 100 mg Versus Ibuprofen 400 mg, Caffeine 100 mg and Placebo in Patients With Postoperative Dental Pain | NCT01929031 |
| Drug-drug Interaction Study of Tivantinib (ARQ 197) With Omeprazole, S-warfarin, Caffeine, Midazolam, and Digoxin in Cancer Subjects | A Phase 1, Open-Label, Single-Sequence Crossover Study Assessing the Effect of Tivantinib (ARQ 197) on the Pharmacokinetics of Omeprazole/S-Warfarin/Caffeine/Midazolam and Digoxin in Cancer Subjects | NCT01517399 |
| Comparison oral caffeine and oral Melatonin on prevention of headache caused by spinal anesthesia in lower limb surgery | Comparison between oral caffeine and oral Melatonin on prevention of headache caused by spinal anesthesia in lower limb surgery | IRCT20141209020258N94 |
| Acute Caffeine Effects on Cardiac Autonomic and Cardiorespiratory Parameters Responses After Aerobic Exercise | Acute Caffeine Effects on Cardiac Autonomic and Cardiorespiratory Parameters Responses After Aerobic Exercise | NCT02917889 |
| Effect of four weeks Concurrent Training and caffeine supplementation on body composition, lipid profile and some hormones in serum of girls with overweight | Effect of four weeks Concurrent Training and caffeine supplementation on body composition, lipid profile and some hormones in serum of girls with overweight | IRCT2015062922973N1 |
| Effect of caffeine on neuropsychological performance and driving ability in healthy volunteers: a double-blind placebo-controlled study. | Effect of caffeine on neuropsychological performance and driving ability in healthy volunteers: a double-blind placebo-controlled study. - Effect of caffeine on neuropsychological performance and driving ability in healthy volunteers: a double-blind placebo-controlled study. | JPRN-UMIN000023576 |
| Evaluation of safety and the effectiveness of Caffeine Plus Siseh anti-hair loss tonic and shampoo | Evaluation of safety and the effectiveness of Caffeine Plus Siseh anti-hair loss line (tonic and shampoo) produced by Sina Trading Company In the prevention and treatment of androgenic hair loss | IRCT20161207031288N8 |
| Caffeine for Hypoxic-Ischemic Encephalopathy | Pharmacokinetics and Safety of Caffeine in Neonates With Hypoxic-Ischemic Encephalopathy | NCT03913221 |
| The survey of changes in catecholamines, perception of pressure and lactate to caffeine-beet water supplement in runners | The effect of high-dose caffeine-beet juice supplementation with high, low dose and placebo on changes in catecholamines, lactate and pressure perception index before intense anaerobic activity in elite runners | IRCT20200707048041N2 |
| Clinical Study to Evaluate Efficacy of New Paracetamol Formulation Compared to Ibuprofen in Headache | A Study to Assess Efficacy Over Placebo and Speed of Onset of Pain Relief of New Paracetamol and Caffeine Tablets as Compared to Ibuprofen in Episodic Tension Type Headache | NCT01842633 |
| Effects of modafinil, caffeine and methylphenidate on functional brain activity and cognitive performance in healthy subjects: a randomized, placebo-controlled, double-blind fMRI study. | Effects of modafinil, caffeine and methylphenidate on functional brain activity and cognitive performance in healthy subjects: a randomized, placebo-controlled, double-blind fMRI study. - MKM | EUCTR2012-003882-17-DE |
| Effect of Caffeine Intake in Vestibular Function | Effect of Caffeine Intake in Vestibular Function: A Randomized Triple-Blind Controlled Trial | NCT02825199 |
| Pre-workout Supplement Versus Caffeine on Energy Expenditure. | Effects of a Multi-ingredient Pre-workout Supplement Versus Caffeine on Energy Expenditure and Feelings of Fatigue During Low-intensity Treadmill Exercise in College-aged Males. | NCT04539054 |
| Oral Testofen, L-citrulline, Resveratrol, and Caffeine supplementation study for sexual function: randomized, double blind, placebo-controlled crossover pilot study. | Oral Testofen, L-citrulline, Resveratrol, and Caffeine supplementation study for sexual function: randomized, double blind, placebo-controlled crossover pilot study. - Testofen, L-citrulline, Resveratrol, and Caffeine supplementation study for sexual function. | JPRN-UMIN000028816 |
| Comparing the efficacy of intravenous Caffeine versus intravenous Aminophylline in reduction of post-spinal anesthesia headache in cesarean sections | Comparing the efficacy of intravenous Caffeine versus intravenous Aminophylline in reduction of post-spinal anesthesia headache in cesarean sections in Amiralmomenin Hospital in 2013 and 2014 | IRCT2016030126865N1 |
| Remote Guided Caffeine Reduction | Remote Guided Caffeine Reduction | NCT04560595 |
| This Study Tests the Effect of Risankizumab on the Metabolism in the Liver of Five Additional Drugs to Study Possible Drug Interactions in Patients With Psoriasis With or Without Psoriatic Arthritis | The Effect of Multiple Subcutaneous Doses of Risankizumab on the Single Dose Pharmacokinetics of Cytochrome P450 Substrates (Caffeine, Warfarin, Omeprazole, Metoprolol and Midazolam) Administered Orally in an Open-label, One-sequence Trial in Patients With Plaque Psoriasis With or Without Concomitant Psoriatic Arthritis | NCT02772601 |
| Research on Parkinson's disease pathogenesis based on analysis of caffeine absorption in patients with Parkinson's disease | Research on Parkinson's disease pathogenesis based on analysis of caffeine absorption in patients with Parkinson's disease - Analysis of caffeine absorption in patients with Parkinson's disease | JPRN-UMIN000022187 |
| Effect of Caffeine on Myocardial Oxygenation | Effect of Caffeine on Myocardial Oxygenation | NCT04585854 |
| Influence of polymorphisms of adenosine A2 receptor and dopamine D2 receptor on mental calculations, blood pressure and pulse rate after intake of caffeine: a double-blind randomized placebo-controlled clinical trial. | Influence of polymorphisms of adenosine A2 receptor and dopamine D2 receptor on mental calculations, blood pressure and pulse rate after intake of caffeine: a double-blind randomized placebo-controlled clinical trial. - Influence of polymorphisms of adenosine A2 receptor and dopamine D2 receptor on the effect of caffeine | JPRN-UMIN000010360 |
| Effects of Caffeine and Coffee on Resting Metabolic Rate, Comparing Normal Weight Men to Obese Men | Effects of Caffeine and Coffee on Resting Metabolic Rate, Comparing Normal Weight Men to Obese Men | NCT02751840 |
| Evaluation of vasodilatory changes and exercise performance to caffeine-beet juice supplementation in runners | The effect of short-term supplementation of caffeine and beet juice with high, low dose and placebo on vasodilator indices and athletic performance in elite runners | IRCT20200707048041N1 |
| Effect of Caffeine on Gestational Diabetes Screening | Effect of Caffeine on Gestational Diabetes Screening | ISRCTN90645333 |
| Associations Between Genetic Markers of Caffeine Metabolism, Appetite Hormones and Body Weight | Associations Between Genetic Markers of Caffeine Metabolism, Appetite Hormones and Body Weight | NCT04514588 |
| Caffeine, Genetic Variation and Athletic Performance | Genetic Modifiers of Caffeine Intake and Athletic Performance | NCT02109783 |
| Comparison of the Effects of celecoxib, celecoxib – caffeine and Ibuprofen on pain control after Surgery | Comparison of the Effects of celecoxib, celecoxib – caffeine and Ibuprofen on pain control after crown lengthening. | IRCT201305253813N2 |
| Efficacy and Safety of the Combination of Ketoprofen and Cyclobenzaprine and Caffeine in Osteomuscular Treatment | Phase III, National, Multicenter, Randomized, Double-blind, Double-masked, Compare the Efficacy of Ketoprofen, Cyclobenzaprine and Caffeine Association Versus Cyclobenzaprine and Caffeine (Miosan Caf®) in the Treatment of Osteomuscular Pain in Adults | NCT02862977 |
| A Dental Pain Study Comparing The Analgesic Efficacy Of Ibuprofen/Caffeine | A PHASE 3, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY COMPARING THE ANALGESIC EFFICACY AND SAFETY OF A SINGLE ORAL DOSE OF A NOVEL FIXED-DOSE COMBINATION OF IBUPROFEN 400 MG WITH CAFFEINE 100 MG TO IBUPROFEN 400 MG AND TO PLACEBO IN THE TREATMENT OF POST-SURGICAL DENTAL PAIN IN OTHERWISE HEALTHY SUBJECTS | NCT02863575 |
| Effects of caffeine and aerobic training on type 2 diabetes | The effects of supplementation with caffeine alone and in combination with aerobic training on some insulin resistance indices in patients with type 2 diabetes: a double-blind and placebo-controlled clinical trial | IRCT20170116031982N2 |
| Anti-fatigue effect of Caffeine-Q10 supplementation | Effect of two-week high-impact Aerobics training and Caffeine plus Coenzyme Q10 supplementation on exercise-induced response of capillary lactate and some serum enzymes in female athletes | IRCT201305124663N13 |
| Effect of CAFfeine on Cognition in Alzheimer's Disease | Multicentre, Randomized, Double-blind, Placebo-controlled Trial Evaluating the Effect of a 30-week Caffeine Treatment on Cognition in Alzheimer's Disease at Beginning to Moderate Stages | NCT04570085 |
| Intravenous Caffeine Citrate versus Magnesium Sulphate for Pain control of Acute Migraine Headache | Comparative assessment of Intravenous Magnesium Sulphate vs. Intravenous Caffeine in Acute Migraine Headache Presenting to the Emergency Department | IRCT2016061315640N2 |
| Caffeine Efficacy in ADCY5-related Dyskinesia | Study of Caffeine Efficacy in ADCY5-related Dyskinesia - a Retrospective Study | NCT04469283 |
| High Versus Low Dose of Caffeine for Apnea of Prematurity | High Versus Low Dose of Caffeine for Apnea of Prematurity: A Double Blind Randomized Control Trial | NCT02103777 |
| Relative Bioavailability of Ibuprofen From a Single Fixed Dose Combination Tablet of Ibuprofen and Caffeine Compared to Single Tablets of Ibuprofen and Ibuprofen Lysinate | Relative Bioavailability of Ibuprofen From a Fixed Dose Combination (FDC) Tablet of Ibuprofen 400 mg and Caffeine 100 mg Compared to a Tablet of Ibuprofen 400 mg and a Tablet of Ibuprofen Lysinate 400 mg Following Oral Administration in Healthy Male and Female Subjects (an Open-label, Randomised, Single-dose, Three-period Crossover Study) | NCT01879371 |
| Direct Effect of Caffeine on Diaphragmatic Muscles | Direct Effect of Caffeine on Diaphragmatic Muscles | NCT04483492 |
| Effects of Oral Nicotine and Caffeine Pouches on Anaerobic Performance, Autonomic Function, Cognition, and Behavior | Effects of Oral Nicotine and Caffeine Pouches on Anaerobic Performance, Autonomic Function, Cognition, and Behavior | NCT06529055 |
| The Impact of Caffeine on Cognition in Schizophrenia | The Impact of Caffeine on Cognition in Schizophrenia | NCT02832401 |
| The Effect of CPC on Aborting Tilt Induced Syncope in Patients With a History of Vasovagal Syncope or Near Syncope | The Effect of Capsaicin-Phenylephrine-Caffeine Formulation on Aborting Tilt Induced Syncope in Patients With a History of Vasovagal Syncope or Near Syncope | NCT04972123 |
| Anti-oxidant effect of Caffeine-Q10 supplementation | Effect of two-week High-impact Aerobic training and caffeine plus Ubiquinone supplementation on serum total anti-oxidant capacity and malondialdehyde in female athletes following once-session exhaustive training | IRCT201206204663N10 |
| Effects of Caffeine on Intermittent Hypoxia in Infants Born Preterm | Pilot Study of Effects of Caffeine on Intermittent Hypoxia in Infants Born Preterm | NCT01875159 |
| The effects of a single administration of a moderate dose of caffeine on cognitive control and spontaneous EEG theta/beta ratio | The effects of a single administration of a moderate dose of caffeine on cognitive control and spontaneous EEG theta/beta ratio - Caffeine and theta/beta ratio | NL-OMON42339 |
| Assessement of the effects of coffee main constituents in none- alcoholic fatty liver patients with type 2 diabetes | Assessement of the effects of coffee main constituents (caffeine and chlorogenic acid) supplementation on inflammatory, metabolic factors, hepatic steatosis and fibrosis in none- alcoholic fatty liver patients with type 2 diabetes | IRCT201707024010N21 |
| Assessment of intravenous caffeine in control of headache in comparison with intravenous Ketorolac | Comparative assessment of Caffeine vs. Ketorolac intravenous administration efficacy in acute Migraine headaches without aura | IRCT2013120315640N1 |
| Effect of ibuprofen + caffeine administration on the reduction of dental sensitivity from in-office bleaching | Effect of anti-inflammatory administration on the reduction of dental sensitivity from in-office bleaching | RBR-48c9xt |
| Acetaminophen plus caffeine in electroconvulsive therapy induced headache | comparison of the effectiveness of acetaminophen and acetaminophen plus caffeine in treatment of electroconvulsive therapy induced headache in psychiatric patients. | IRCT20170207032435N3 |
| Influence of MCT and caffeine on ketogenesis (ßHB) | Influence of MCT and caffeine on ketogenesis (ßHB) - MCTCoffKeto | DRKS00015098 |
| Effectiveness of phenytoin-caffeine combination in general seizure | Effectiveness of phenytoin-caffeine combination in general seizure - The study of phenytoin-caffeine combination in general seizure | JPRN-UMIN000012255 |
| The effect of caffeine on people's perception of tinnitus | Effect of caffeine intake in tinnitus | RBR-4crf4d |
| Caffeine and Neurologic Recovery Following Surgery and General Anesthesia | Caffeine and Neurologic Recovery Following Surgery and General Anesthesia | NCT03577730 |
| Caffeine Consumption in Glaucoma Patients and Healthy Subjects | Acute Changes in Optic Nerve Head (ONH) and Macular Blood Flow After Caffeine Consumption in Glaucoma Patients and Healthy Subjects: A Quantitative Optic Coherence Tomography Angiography (OCTA) Study | NCT03675412 |
| STUDY TO COMPARE CAFFEINE AND AMINOPHYLLINE IN THE MANAGEMENT OF APNEA OF PREMATURITY | COMPARATIVE STUDY TO EVALUATE EFFICACY AND ADVERSE EFFECTS OF CAFFEINE AND AMINOPHYLLINE IN THE MANAGEMENT OF APNEA OF PREMATURITY | CTRI/2018/05/014329 |
| Effect of preemptive novafen on pain relief after impacted tooth surgery | Survey of effect of preemptive combination of acetaminophen, ibuprofen and caffeine (novafen) on pain relief and analgesic use after surgery of impacted mandible third molars | IRCT201201078639N1 |
| Prevention of UV- Induced Apoptosis by Caffeine | Prevention of Experimental Ultraviolet Induced Apoptosis in Explanted Human Lens Epithelial Cells Enriched With Caffeine: a Pilot Study | NCT03534973 |
| Synthetic and Natural Caffeine on Hemodynamic Parameters in Young, Healthy Volunteers | Comparison of Synthetic and Natural Caffeine on Hemodynamic Parameters in Young, Healthy Volunteers: A Randomized, Double Blind, Crossover Study | NCT03495063 |
| Arrhythmic Effects of Hight Dose Caffeine | Effect of High-dose Caffeine on Cardiac Arrhythmias in Patients With Heart Failure - a Randomized Clinical Trial | NCT02045992 |
| A Drug Interaction Study of KW-6356 With Midazolam, Caffeine, or Rosuvastatin | A Drug Interaction Study of KW-6356 With Midazolam, Caffeine, or Rosuvastatin | NCT03970798 |
| Effect of caffeine on QTc | Compare the effects of caffeine on QTc interval and blood pressure during isometric and isotonic Contractions in Male athletes and non-athletes | IRCT20171216037906N1 |
| Influence of Flavonoids and Caffeine Supplementation on Resting Metabolism | A Randomized, Cross-Over Clinical Trial to Evaluate the Acute Effects of Mixed Flavonoid and Caffeine Ingestion on Energy Expenditure and Fat Oxidation in Healthy Adult Women | NCT03752125 |
| Comparison of analgesic effect - the combination of acetaminophen and ibuprofen in the presence and absence of caffeine on pain after root canal treatment | Comparison of analgesic effect - the combination of acetaminophen and ibuprofen in the presence and absence of caffeine on pain after root canal treatment | IRCT201306121760N24 |
| Neuroplastic Alterations of the Motor Cortex by Caffeine | Neuroplastic Alterations of the Motor Cortex by Caffeine: Differences Between Caffeine and Non-caffeine Users and Influence of Vigilance During Stimulation | NCT04011670 |
| Caffeine to improve oxygen levels in mildly preterm babies (Latte Dosage Trial) | Caffeine prophylaxis to improve intermittent hypoxaemia in infants born late preterm: a randomised controlled dosage trial (Latte Dosage Trial) | ACTRN12618001745235 |
| Study of the use of caffeine in performance in cyclists. | Effect of chronic and / or acute Caffeine in performance on the test time-trial on cyclists | RBR-5745nv |
| Effect of caffeine on Growth Hormone and Testosterone | The Effect of Caffeine Supplementation on Growth Hormone and Testosterone after Resistance Exercise According to the Polymorphism of Cytochrome P450 | IRCT20170405033231N2 |
| Caffeine and central fat reduction | The Effect of 6 Weeks Caffeine Supplementation with Aerobic Exercise on Central Body Fat in Overweight Women. | IRCT20111025007903N11 |
| Caffeine and decaffeine coffee effects on serum uric acid and urate clearance, an open-label, randomized controlled prospective study. | Caffeine and decaffeine coffee effects on serum uric acid and urate clearance, an open-label, randomized controlled prospective study. | TCTR20190304003 |
| Comparison of intravenous mannitol and acetaminophen caffeine in postural headache after cesarean section | Comparison of intravenous mannitol and oral acetaminophen caffeine in treatment of post dural puncture headache after cesarean section by spinal anesthesia | IRCT20121006011020N12 |
| The Effects of a Combination of TeaCrine®, Dynamine, and Caffeine in Law Enforcement | The Effects of a Combination of TeaCrine®, Dynamine, and Caffeine on Marksmanship Accuracy and Reaction Time in ROTC Members, Military, and Law Enforcement Following a Mentally Fatiguing Protocol | NCT03937687 |
| Caffeine phonophoresis versus shock wave therapy for adult females with cellulite | Caffeine phonophoresis versus shock wave therapy for adult females with cellulite: A randomized controlled trial | PACTR201902473450574 |
| Effect of on premature ejaculation | The effect of caffeine in comparison to conventional squeeze technique on controlling men with premature ejaculation, a Randomized Controlled Trial | IRCT2013091614677N1 |
| The Influence of Caffeine Supplementation on Specific Performance and Training Activities | The Influence of Caffeine Supplementation on Discipline-Specific Performance and Training Activities in Combat Sports and Speed-Strength Disciplines | NCT03822663 |
| Experiencing of double blind study of caffeine intake for medical students | Experiencing of double blind study of caffeine intake for medical students - Experiencing of double blind study for medical students | JPRN-UMIN000032060 |
| Comparison of the Effect of Caffeine Citrate with Placebo on the Wake-Up Rate of Children 12-36 months After Outpatient Surgery under General Anesthesia with Inhaled Anesthetics | Comparison of the Effect of Caffeine Citrate with Placebo on the Wake-Up Rate of Children 12-36 months After Outpatient Surgery under General Anesthesia with Inhaled Anesthetics | IRCT20190511043550N1 |
| 13C-caffeine breath test for the identification of single nucleotide polymorphisms associated with caffeine metabolism | 13C-caffeine breath test for the identification of single nucleotide polymorphisms associated with caffeine metabolism - 13C-caffeine breath test for the identification of single nucleotide polymorphisms associated with caffeine metabolism | JPRN-UMIN000036735 |
| Does caffeine improve bodybuilding performance? | Caffeine supplementation: ergogenic resource or placebo effect? | RBR-3h5hffm |
| Study of the Safety and Efficacy of a Caffeine-based Antifibrosis Cream in Patients With Breast Cancer Undergoing Radiation Therapy | A Phase 1, Randomized, Double Blinded, Placebo Controlled Study of the Safety and Efficacy of a Caffeine-based Antifibrosis Cream in Patients With Breast Cancer Undergoing Radiation Therapy | NCT03768492 |
| A prospective randomized controlled trial for different maintaining doses of caffeine therapy for apnea of very low birthweight infants | A prospective randomized controlled trial for different maintaining doses of caffeine therapy for apnea of very low birthweight infants | ChiCTR1800019204 |
| Short term evaluation of caffeine based eye-drops in healthy volunteers. | Short term evaluation of the ocular response to caffeine eye-drops and caffeine plus atropine eye-drops in healthy volunteers.. | ACTRN12618000196246 |
| Interaction between herbal remedies (danshen and baizhi) and caffeine | Caffeine/Angelica dahurica and caffeine/Salvia miltiorrhiza metabolic inhibition in humans: In vitro and in vivo studies. | ISRCTN83028296 |
| Analysis of the Effects of Caffeine on cognitive abilities and anxiety | Analysis of the Effects of Caffeine on cognitive abilities and anxiety | RBR-3tnjtq |
| Caffeine and anaerobic exercise performance: an exploration of caffeine’s effects on performance in young men and the influence of genotype on the variation in responses | The effect of CYP1A2 genotype on the ergogenic effects of caffeine during anaerobic exercise | ACTRN12619000885190 |
| The Effect Of Combination of Drugs Acetaminophen, Aspirin, Caffeine (AAC) on Migraine Headaches | Comparison the Effects of Combined Drugs Acetaminophen,Aspirin,Caffeine With Ibo Profen On Acute Attacks of Migraine Headaches | IRCT2017052930680N4 |
| Caffeine's Effects on improving Physical Performance | The biology of Ergogenic Caffeine Effects | RBR-39jnp4 |
| Effects of intravenous caffeine on Fractional Flow Reserve measurements in coronary artery disease | To compare fractional flow reserve (FFR) before and after intravenous caffeine administration in coronary artery disease patients to evaluate effect of caffeine on FFR levels | ACTRN12614000142639 |
| Paracetamol Vs Caffeine Vs Codeine in the Management of Post Traumatic Pain in Emergencies | Paracetamol Vs Paracetamol-Caffeine Association Vs Paracetamol-Codeine Association in the Management of Post Traumatic Pain in Emergencies | NCT05229965 |
| Study to Find Out the Optimal Dose of Caffeine in the Combination Tablet of Naproxen Sodium and Caffeine in Patients Experiencing Moderate to Severe Pain After Having Wisdom Teeth Removed | A Randomized, Double-Blind, Single-Dose, Parallel, Placebo-Controlled Trial to Determine the Dose of Caffeine in a Fixed Dose Combination Tablet of Naproxen Sodium and Caffeine to Effectively Alleviate Postsurgical Dental Pain | NCT04132336 |
| Caffeine as Respiratory Stimulant in Preterm Infants | High Versus Low Dose Caffeine as Respiratory Stimulant in Preterm Infants | NCT04144712 |
| Caffeine for Preterm Infants With Apnea of Prematurity(AOP) | Caffeine for Preterm Infants With Apnea of Prematurity(AOP): a Randomized Controlled Trial | NCT03298347 |
| """Effect of caffeine, aminophylline and adrenocorticotropin on headache after spinal anesthesia""" | Comparison of the effectiveness of adernocorticotropin and aminophylline and caffeine;On the treatment of headache after tearing in patients with spinal aneshesia. | IRCT20180325039148N4 |
| To check the difference of two products that is product A (Xtenergy caffeine 60%, 200 mg caffeine/ Capsule) and product B (Natural caffeine extract 99%,200 mg caffeine/Capsule) in the healthy adult human beings. | A double blind, balanced, randomized, single-dose, two-treatment, two-sequence, two-period, crossover oral bioequivalence study of Product A (Xtenergy caffeine60%, 200 mg caffeine/ Capsule)of OmniActive Health Technologies Ltd., Indiaand Product B(Natural caffeine extract 99%,200 mg caffeine/Capsule)of OmniActive Health Technologies Ltd., Indiain healthy adult human subjects under fasting condition. | CTRI/2019/11/022135 |
| Prevention of Atrial Fibrillation Following Valvular Replacement With Cardiopulmonary Bypass: a Prospective, Randomized Clinical Study Comparing Oral Caffeine With Placebo | Prevention of Atrial Fibrillation Following Valvular Replacement With Cardiopulmonary Bypass: a Prospective, Randomized Clinical Study Comparing Oral Caffeine With Placebo | NCT01999829 |
| Randomized controlled trial (RCT) comparing between High versus Standard dose caffeine citrate for apnoea in prematurity | Randomized controlled trial (RCT) comparing between High versus Standard dose caffeine citrate for apnoea in prematurity for premature baby with gestational age 28 to 32 weeks. | ACTRN12619001708145 |
| Effect of prophylactic Caffeine on duration of respiratory support in preterm neonates with RDS | Effect of prophylactic Caffeine on the need for oxygen duration and respiratory support in preterm neonates with weight 1250-2000 gr with RDS requiring nasal CPAP | IRCT20170627034782N2 |
| Effect of Creatine and Caffeine on Muscle Performance | Effects of Creatine and Caffeine Co-Supplementation on Muscle Mass and Muscle Performance in Trained Young Adults | NCT04290819 |
| The effect of stretching exercises and caffeine tablets on headache after spinal anesthesia | Comparison the effect of stretching exercises and caffeine tablets on reducing headache after spinal anesthesia | IRCT20190131042569N1 |
| Prophylactic caffeine for prevention of apnea in preterm neonate with weight less than 1200 gr. | Prophylactic caffeine for prevention of apnea in preterm neonate with weight less than 1200 gr. | IRCT2013110610026N3 |
| Timing of Meal and Caffeine Intake on Substrate Use and Exercise Efficiency | Timing of Meal and Caffeine Intake on Substrate Use and Exercise Efficiency in Healthy Individuals | NCT04106752 |
| Influence of Caffeine on HRV and Exercise Performance in Spinal Cord Injury | Influence of Caffeine on Heart Rate Variability and Exercise Performance in in Tetraplegic and Paraplegic Subjects Compared to Able-bodied Subjects | NCT02083328 |
| Oral Caffeine Use for Pain Management in AIS Patients After Spinal Fusion | Oral Caffeine Decreases the Frequency of Opioid Demand in AIS Patients After Spinal Fusion | NCT04950660 |
| Malignant Hyperthermia - A new simple diagnostic test | Assessing Calcium flux in single muscle fibres in response to halothane and caffeine to diagnose Malignant Hyperthermia. | ACTRN12619001260112 |
| The effects of Caffeine on Attentional Networks | The effects of Caffeine on Attentional Networks in Healthy Volunteers | ACTRN12618000115235 |
| Effects of Modafinil and Caffeine on vigilance in low, medium and high caffeine consumers during the circadian trough in healthy RNLAF aircrew: a randomized controlled trial | Effects of Modafinil and Caffeine on vigilance in low, medium and high caffeine consumers during the circadian trough in healthy RNLAF aircrew: a randomized controlled trial - MOCAFFE | NL-OMON44344 |
| Effect of Caffeine Administration on Responses to Physical Exercise | Effect of Mouthwash with Nutritional Products containing Caffeine on the Immunometabolic Profile and Physical Performance | RBR-9jk5xn |
| Effect of Early Use of Caffeine Citrate in Preterm Neonates | Effect of Early Use of Caffeine Citrate in Preterm Neonates Needing Respiratory Support. | NCT04001712 |
| The Acute Effects of Caffeine on Exercise and Cognition | The Acute Effects of Moderate Intensity Exercise and Caffeine Ingestion on Cognition in Non-Caffeine Consumers and Caffeine Consumers | NCT03400423 |
| """Potential Effect of Acute and Chronic Caffeine Administration on Platelet Reactivity in Patient With Coronary Artery Disease on Dual Antiplatelet Therapy""" | """Potential Effect of Acute and Chronic Caffeine Administration on Platelet Reactivity in Patient With Coronary Artery Disease on Dual Antiplatelet Therapy""" | NCT02054988 |
| Effects of Modafinil and Caffeine on vigilance in low, medium and high caffeine consumers during the circadian trough in healthy RNLAF aircrew | Effects of Modafinil and Caffeine on vigilance in low, medium and high caffeine consumers during the circadian trough in healthy RNLAF aircrew: a randomized controlled trial | NL-OMON22963 |
| Drugs that lead to early awakening from general anaesthesia with propofol | Comparison of effect of caffeine and aminophylline on recovery from totalintravenous anaesthesia with propofol and fentanyl in laparoscopicHysterectomy: A randomized double blinded controlled trial. | CTRI/2019/06/019882 |
| A Study to Determine if Caffeine Accelerates Emergence From Propofol Anesthesia | A Randomized, Double-Blinded, Placebo-Controlled Study to Determine if Caffeine Citrate Accelerates Emergence From Anesthesia | NCT03360903 |
| The effect of taking caffeine by the mother before performing biophysical profile on fetal biophysical profile | Comparison of the effect of caffeine consumption and voice stimulation before biophysical profiling on the biophysical profile of fetal profile in pregnant women with single pregnancy | IRCT20190304042912N2 |
| Effect of parenteral caffeine citrate for prevention of apnea in very preterm neonates in NICU ward | The survey of the effect of parenteral caffeine citrate for prevention of apnea in very preterm neonates in NICU part of Shahid-Motahary hospital for one year | IRCT2017102637023N1 |
| Moderately Preterm Infants With Caffeine at Home for Apnea (MoCHA) Trial | Randomized Controlled Trial of Home Therapy With Caffeine Citrate in Moderately Preterm Infants With Apnea of Prematurity | NCT03340727 |
| Intermittent Hypoxia and Caffeine in Infants Born Preterm | Intermittent Hypoxia and Caffeine in Infants Born Preterm (ICAF) | NCT03321734 |
| Caffeine Treatment in in the Delivery Room | Treatment With Caffeine of Very Preterm Infant in the Delivery Room: the CAFROOM Feasibility Study | NCT04044976 |
| Can consuming caffeine after a nap improve productivity, alertness and safety? | Combining nap and caffeine countermeasures to improve productivity, alertness and safety in healthy adults undergoing a simulated nightshift | ACTRN12617001486314 |
| A retrospective study of demographic and lifestyle factors associated with caffeine and dietary supplement use | A retrospective study of demographic and lifestyle factors associated with caffeine and dietary supplement use | ISRCTN15296828 |
| Body Composition Changes With Albuterol and Caffeine Versus Placebo in Adolescents | Effect on Body Composition With Albuterol and Caffeine Versus Placebo in Adolescents: A Pilot Study | NCT02740660 |
| The Role of Tea Catechins and Caffeine in Relation to Energy Metabolism | The Role of Tea Catechins and Caffeine in Relation to Energy Metabolism in Man | NCT00611416 |
| Caffein Consumption and Response Inhibition | Does Caffeine Consumption Improve Response Inhibition to Food Cues? | NCT01815203 |
| Caffeine Disposition After Inhalation | Pharmacokinetics and Pharmacodynamics of a 100 mg Caffeine Dose After Oral Consumption of an Energy Drink or Inhalation Using the Aeroshot Administration Device | NCT02184104 |
| Drug Drug Interaction Study Between BI 201335 and BI 207127 in Chronic Hepatitis C Infected Patients | A Multi-centre, Open Label, Parallel Group Trial to Evaluate the Pharmacokinetic Interactions Between BI 207127 (600 mg t.i.d. or 600 mg b.i.d.) and BI 201335 (120 mg q.d.) Given in Combination With Ribavirin for 24 Weeks, and Their Combined Effect on the Pharmacokinetics of Tenofovir, Raltegravir, Caffeine (the Probe Drug Substrate for CYP1A2), Tolbutamide (the Probe Drug Substrate for CYP2C9) and Midazolam (the Probe Drug Substrate for CYP3A4) in Treatment naïve Patients and Prior Treatment Relapse or Partial Responder Patients With Genotype 1 Chronic Hepatitis C Infection | NCT01525628 |
| """The Effects of Caffeine on Overactive Bladder Symptoms and Mental Health in Postmenopausal Women""" | """The Effects of Caffeine on Overactive Bladder Symptoms and Mental Health in Postmenopausal Women""" | NCT02180048 |
| Reducing breathing spells in preterm infants: air flow versus caffeine | Reducing Apneas in Preterm Infants:Low-Flow versus Caffeine | NL-OMON20329 |
| Assessing the effect of caffeine on attention in patients with and without dementia | Assessing the effect of caffeine on attention in patients with and without dementia: A double blind, randomised, cross over trial | ISRCTN78129879 |
| Reducing Apneas in Preterm Infants: Low-Flow versus Caffeine | Reducing Apneas in Preterm Infants: Low-Flow versus Caffeine - RALFC | NL-OMON40827 |
| Effects of caffeine and carnitine in athletes | The effects of carnitine and caffeine supplementation on body fat percentage, oxidative stress, lipid profile, inflammatory and atherosclerotic factors in semi-professional athletes | IRCT2014100619411N1 |
| Study to examine whether caffeine can relieve breathlessness caused by ticagrelor (TROCADERO) | TRIAL OF CAFFEINE TO ALLEVIATE DYSPNEA RELATED TO TICAGRELOR(TROCADERO) A double-blinded, placebo-controlled, randomized, multicenter, development phase II study - TROCADERO | EUCTR2013-004412-22-SE |
| Comparing the effectiveness of the combination of caffeine, L-theanine and piperin compared to placebo and pure caffeine in increasing attention | Investigating the effectiveness of capsules containing the combination of caffeine, L-theanine and piperin compared to pure caffeine and placebo in improving attention in healthy people | IRCT20160306026938N19 |
| Caffeine for breathing at birth | Caffeine treatment for stimulation of spontaneous breathing in preterm infants at birth | NL-OMON24252 |
| Testing Potential Synergistic Effects of Albuterol and Caffeine on Metabolic Rate | Testing Potential Synergistic Effects of Albuterol and Caffeine on Metabolic Rate. | NCT02135965 |
| Effect of Caffeine on Ocular Circulation in High Myopes | Effect of Caffeine on Ocular Circulation in High Myopes | NCT03294967 |
| Acute Caffeine Ingestion on Futsal Performance | Effects of Acute Caffeine Ingestion on Futsal Performance in Sub-elite Players | NCT04852315 |
| Target Weaning Oxygen to Determine Cafffeine Duration for AOP | Target Weaning Oxygen to Determine Duration of Caffeine for Apnea of Prematurity: a Multicenter, Prospective, Randomized Controlled Trial | NCT04868565 |
| Pharmacokinetic Drug-drug Interaction Study of Dovitinib (TKI258) in Patients With Advanced Solid Tumors | A Phase I, Multi-center, Open-label, Drug-drug Interaction Study to Assess the Effect of TKI258 on the Pharmacokinetics of Caffeine, Diclofenac, Omeprazole and Midazolam Administered as a Four-drug Cocktail in Patients With Advanced Solid Tumors, Excluding Breast Cancer | NCT01596647 |
| Effect of the use of L-Arginine, Caffeine or Creatine supplements associated with physical activity in women with Polycystic Ovary Syndrome with Metabolic Syndrome | Thermogenic Adaptation in Patients with Polycystic Ovarian Syndrome with Metabolic Syndrome Supplemented by Chronology with L-Arginine, Caffeine or Creatine and Training Resisted Exercise - Randomized Study | RBR-9832jt |
| study of of the effect of caffeine consumption on the efficiency of surgical closures | Prospective randomized crossover study of the effect of caffeine consumption on the efficiency of surgical closures - coffee | JPRN-UMIN000043695 |
| Effect of Caffeine on Heart Rate Variability in Newborns | Effect of Caffeine for Apnoea Treatment on Heart Rate Variability in Newborns | NCT04869176 |
| Effect of Feedings on Caffeine in Premature Infants | Effect of Feedings on Caffeine Pharmacokinetics and Metabolism in Premature Infants | NCT02293824 |
| Effects of Caffeine and Intermittent Hypoxia on Leg Function in Human Spinal Cord Injury | The Effects of Intermittent Hypoxia on Leg Function in Human Spinal Cord Injury (Caffeine Substudy) | NCT02323698 |
| An evaluation of the drug interaction potential of modafinil in healthy volunteers, using a cocktail approach | An investigation of the proportional change in area under the concentration-time curves for five orally administered CYP P450 probes (caffeine, losartan, omeprazole, dextromethorphan, midazolam) when administered with and without single-dose and steady-state oral modafinil, in twelve healthy adult volunteers. | ACTRN12614000451606 |
| Perceptual Effects of Caffeine and Nabilone (PECAN) | Nabilone and caffeine effects on the perceptions of visually, auditory, tactile and multimodal illusions in healthy volunteers | ACTRN12618001292268 |
| Effect of low-caffeine green tea against sleep and stress in the elderly | Effect of low-caffeine green tea against sleep and stress in the elderly - Sleep and stress in the elderly | JPRN-UMIN000016533 |
| Evaluating the Role of Expectations in Response to Caffeine Consumption: An RCT | Evaluating the Role of Expectations in Response to Caffeine Consumption: A Randomized Control Trial | NCT02461693 |
| Does a Caffeine Gum Improve 5 km Run Performance in a Competition/Field Setting? | Does a Commercial Caffeine Supplement Improve 5 km Run Performance in a Field Setting? | NCT02473575 |
| Assessment of caffeine efficacy on relapse prevention on methamphetamine dependent client who refer for treatment | Comparison of caffeine and placebo in relapse reduction for patients who refer for treatment. | IRCT2013120215628N1 |
| An open-label, 4-arms study to assess the drug-drug interaction of PXL770 with repaglinide, tolbutamide, midazolam, and caffeine in healthy subjects | An open-label, 4-arms study to assess the drug-drug interaction of PXL770 with repaglinide, tolbutamide, midazolam, and caffeine in healthy subjects - DDI study PXL770 with repaglinide, tolbutamide, midazolam, and caffeine | NL-OMON50829 |
| Different doses effect of caffeine on muscle soreness | Effect of a single resistance training session and acute different dosages of caffeine intake on some DOMS indices in male volleyball players | IRCT201112244663N7 |
| Caffeine and Sodium Citrate Ingestion | Effects of Caffeine and Sodium Citrate Ingestion in 1500m Wheelchair Racing Athletes | NCT01591226 |
| Effects of Caffeine in Hydration and Energy Metabolism | Effects of Caffeine Ingestion in Total-body Water, Extra and Intracellular Water Distribution, and Energy Metabolism | NCT01477294 |
| Caffeine and the Autonomic Nervous System | Impact of Caffeine Consumption on Markers of the Autonomic Nervous System | NCT04886869 |
| CNS Drug Effect Profiling in Children: an Educational Class Experiment using Caffeine as a Model. | CNS Drug Effect Profiling in Children: an Educational Class Experiment using Caffeine as a Model. - Caffeine challenge in adolescents. | NL-OMON32655 |
| Study on the effect of caffeine intake on tear production and its correlation with genetic variation | Study on the effect of caffeine intake on tear production and its correlation with genetic variation - Study on the effect of caffeine intake on tear production | JPRN-UMIN000002903 |
| A Phase III Randomized Controlled Study Of Efficacy & Tolerability Of Fixed Dose Combination Of Paracetamol 500 Mg + Phenylephrine Hydrochloride 5mg + Diphenhydramine 25 Mg + Caffeine 30 Mg (Nasivion Tablets) Versus Paracetamol 500 Mg And A Fixed Dose Combination Containing Paracetamol 500 Mg + Chloropheneraminemaleate 2 Mg + Phenylephrine 10 Mg (Control) In Patients With Common Cold (Coryza) | A Phase III Randomized Controlled Study Of Efficacy & Tolerability Of Fixed Dose Combination Of Paracetamol 500 Mg + Phenylephrine Hydrochloride 5mg + Diphenhydramine 25 Mg + Caffeine 30 Mg (Nasivion Tablets) Versus Paracetamol 500 Mg And A Fixed Dose Combination Containing Paracetamol 500 Mg + Chloropheneraminemaleate 2 Mg + Phenylephrine 10 Mg (Control) In Patients With Common Cold (Coryza) | CTRI/2009/091/000879 |
| The Effect of Caffeine in Elderly Citizen Following Eight Hour Abstinence From Caffeine Containing Drinks & Foods | The Effect of Caffeine as Endurance Enhancing Drug in the Elderly Following Eight Hour Abstinence From Caffeine Containing Drinks and Foods | NCT01048515 |
| Effects of Caffeine on Methacholine Challenge and Exhaled Nitric Oxide Levels. | The Effects of Caffeine on Exhaled Nitric Oxide Levels and Methacholine PC20 | NCT01057875 |
| A Study to Evaluate How Daily Dosing With Enzalutamide Affects the Metabolism of Caffeine and Dextromethorphan in Men With Prostate Cancer | A Phase 1 Open-label Study to Evaluate the Effect of Multiple Doses of Enzalutamide on the Pharmacokinetics of Substrates for CYP1A2 and CYP2D6 in Male Subjects With Prostate Cancer | NCT02225093 |
| Investigation of CYP1A2 drug metabolism activity in Europeans and South Asians | Ethnic differences in Drug Metabolism: Investigation of CYP1A2 drug metabolism activity by testing caffeine in Europeans and South Asians | ACTRN12610000169044 |
| Effect of Oral Caffeine and L-Citrulline Supplementation on Arterial Function in Healthy Males | Effect of Oral Caffeine and L-Citrulline Supplementation on Arterial Function in Healthy Males | NCT02214290 |
| Caffeine/Propranolol Intervention for Acute Migraine | Randomized Double-Blind Study to Evaluate the Dose-Related Efficacy and Safety of Caffeine/Propranolol in the Treatment of Acute Migraine | NCT01080677 |
| Neurophysiological Reserve With Caffeine Manipulation | Neurophysiological Reserve: Peripheral and Central Effects of Caffeine Manipulation | NCT01167478 |
| Efficacy and Safety Study to Compare Ibuprofen + Caffeine With Ibuprofen Alone in the Treatment of Headache | A Clinical Multicenter, Phase III, Randomized, Double-blind, Prospective and Comparative Trial to Evaluate the Efficacy and Safety of the Combination of Ibuprofen + Caffeine in the Treatment of Headache Attacks, Compared to Ibuprofen Alone. | NCT01172405 |
| Pharmacokinetic Study to Investigate Low-dose Combinations of a Cocktail of Seven Drugs for Simultaneous Phenotyping of Cytochromes | "Single-center, Randomized, Five-way Crossover Study to Investigate Low-dose Combinations of Caffeine, Efavirenz, Losartan, Omeprazole, Metoprolol, Chlorzoxazone and Midazolam (""Basel Cocktail"") for Simultaneous Phenotyping of CYP1A2, CYP2B6, CYP2C9, CYP2C19, CYP2D6, CYP2E1 and CYP3A4 in Healthy Male Subjects" | NCT01187862 |
| Caffeine for Motor Manifestations of Parkinson's Disease | Caffeine for Motor Manifestations of Parkinson's Disease: An Open-Label Dose-Response Study. | NCT01190735 |
| The effect of caffeine supplementation on anaerobic power, some oxidative stress indices, and appetite in female athletes after a single bout of wingate test. | The effect of caffeine supplementation on anaerobic power, some oxidative stress indices, and appetite in female athletes after a single bout of wingate test. | IRCT138806301197N3 |
| Interaction of Caffeine and Hydration on Voice | Effects of the Interaction of Caffeine and Hydration on Voice Performance | NCT01435837 |
| Effect of a mouthwash with caffeine on oral bacterial species in healthy subjects | Effect of a mouthwash with caffeine on oral bacterial species in healthy subjects - Effect of caffeine on oral bacterial species | JPRN-UMIN000004379 |
| Effects of Caffeine on Women's Sexual Arousal | The Effects of Caffeine on Female Genital Arousal | NCT01242046 |
| Efficacy and Safety of Acetaminophen, Aspirin and Caffeine With Sumatriptan in the Acute Treatment of Migraine | A Multi-center, Randomized, Double-blind, Parallel-group Single-dose, Placebo-controlled Study Comparing the Efficacy and Safety of Acetaminophen, Aspirin and Caffeine With Sumatriptan in the Acute Treatment of Migraine. | NCT01248468 |
| Effects of Caffeine and Mental Fatigue on Selective Attention | Effects of Caffeine and Mental Fatigue on Selective Attention - Caffeine, mental fatigue and attention | NL-OMON34588 |
| Effects of Theobromine and Caffeine on Mood, Cognition and Blood Pressure | Temporal Change of Mood and Cognition in Healthy Subjects After Consumption of Theobromine and/ or Caffeine | NCT01288547 |
| Combined Effects of Alcohol and Caffeine | Combined Effects of Alcohol and Caffeine | NCT01289561 |
| Cognitive Hyper-performance - Effects of Stimulating Substances in Chess-players | Phase I Study About Effects of Caffeine, Methylphenidate, Modafinil and Placebo on Cognitive Performance of Chess Players. | NCT01834547 |
| Cognitive and Cerebral Blood Flow Effects of 2-week Caffeine Abstinence or Maintenance | Behavioural and Cerebral Haemodynamic Effects of Caffeine Withdrawal and Caffeine Administration Following 2-week Maintenance or Abstinence | NCT01376882 |
| Paracetamol With Caffeine to Treat Episodic Tension Type Headache | A Study to Assess the Efficacy of Paracetamol Taken in Combination With Caffeine for the Treatment of Episodic Tension Type Headache | NCT01755702 |
| Acetylsalicylic Acid (ASA) + Paracetamol + Caffeine Combination Compared With ASA + Paracetamol as Well as ASA, Paracetamol, and Caffeine in Headache Patients | A Double-blind, Randomized, Placebo-controlled Clinical Trial to Confirm the Rationale of the ASA + Paracetamol + Caffeine Combination Compared With ASA + Paracetamol as Well as ASA, Paracetamol, and Caffeine in Headache Patients | NCT02183688 |
| Ibuprofen Versus Ibuprofen Plus Caffeine in the Treatment of Migraine. | National, Controlled, Randomized, Double-blind, Parallel Study to Investigate the Efficacy of 2 Capsules of Ibuprofen 400mg in Association With Caffeine 100mg in Fixed Dose Combination Compared to Two Capsules of Ibuprofen 400mg in the Treatment of Migraine | NCT01426971 |
| A clinical trial study to determine the oral bio-availability of Caffxtend capsules. | An open-label, balanced, randomized, single dose, two treatment, two sequence, two period, two way crossover oral bio-availability study comparing caffxtend capsules 200 mg (caffeine long acting beadlets 50N 400mg, equivalent to natural caffeine 200 mg, filled in to capsules) manufactured by Inventia healthcare limited with caffeine capsules 200 mg manufactured by Unicorn natural products ltd in healthy adult human subjects under fasting conditions. - CAFF | CTRI/2021/06/034185 |
| Caffeine Citrate for the Treatment of Apnea Associated With Bronchiolitis in Young Infants | Caffeine Citrate for the Treatment of Apnea Associated With Bronchiolitis in Young Infants: A Randomized, Double Blind, Controlled Trial (RCT) | NCT01435486 |
| Does Caffeine Reduce Postoperative Bowel Paralysis After Elective Colectomy? | Does Caffeine Reduce Postoperative Bowel Paralysis After Elective Colectomy? - A Randomized, Placebo-controlled Trial | NCT02510911 |
| Impact of Caffeine Intake on Autonomic Parameters in the Exercise of Strength | Impact of Caffeine Intake Before Exercise on the Neural Regulation of the Cardiovascular System in Physically Active Adults | NCT03899675 |
| Effect of low-caffeine green tea against sleep and stress in the middle-aged people | Effect of low-caffeine green tea against sleep and stress in the middle-aged people - Sleep and stress in the middle age | JPRN-UMIN000019411 |
| CAFFEINE TREATMENT IN DELIVERY ROOM FOR VERY PRETERM INFANTS : A FEASIBILITY STUDY | CAFFEINE TREATMENT IN DELIVERY ROOM FOR VERY PRETERM INFANTS : A FEASIBILITY STUDY - CAFFEINE IN DELIVERY ROOM | EUCTR2018-003626-91-IT |
| Caffeine effect on exercise-induced damages in non-athletes | Effect of downhill running and short-term caffeine supplementation on some of delayed onset muscle soreness indices in male non-athletes | IRCT201203104663N8 |
| Efficacy of Energy Shots and Caffeine for Energy and Wakefulness Levels | "Efficacy of ""5-hour Energy""®, ""5-Hour Energy Decaf""®, and Caffeine for Perceived Energy and Wakefulness" | NCT01755299 |
| Early Versus Late Caffeine for ELBW Newborns | A Randomized Double Blind Controlled Trial of Early Versus Late Caffeine for Extremely Low Birth Weight Newborns | NCT02524249 |
| Does caffeine reduce dipyridamole-induced protection against ischemia-reperfusion injury? | Does caffeine reduce dipyridamole-induced protection against ischemia-reperfusion injury? - dipy001 | NL-OMON30237 |
| Randomized controlled trial to detect effectiveness of caffeine for college students -part of the public health lectures and training in 2015- | Randomized controlled trial to detect effectiveness of caffeine for college students -part of the public health lectures and training in 2015- - Coffee trial in public health class 2015 | JPRN-UMIN000019645 |
| Caffeine to Reduce Mechanical Ventilation in Preterm Infants | Use of Caffeine to Reduce Length of Mechanical Ventilation in Preterm Infants | NCT01751724 |
| Prophylactic Versus Therapeutic Caffeine for Apnea of Prematurity | Prophylactic Versus Therapeutic Caffeine for Apnea of Prematurity | NCT02677584 |
| Non Invasive Measurement of the Haemodynamic Parameters and of the Advanced Glycation End Products (AGEs) Levels | Non Invasive Measurement of the Haemodynamic Parameters and of the Advanced Glycation End Products (AGEs) Levels in Students Smokers and in Students Who Intake Caffeine (NONINVASHAEMOAGES) | NCT02544165 |
| The Effect of Caffeine on Acupuncture Analgesia With the Human Pain Model | A Single Center, Double Blind, Randomized, Parallel-group Study to Assess the Effect of 200mg Caffeine,400mg Caffeine and Decaffeinated on Acupuncture Analgesia With the Human Pain Model | NCT02577770 |
| Caffeine as a Therapy for Parkinson's Disease | Caffeine as a Therapeutic Agent in Parkinson's Disease | NCT01738178 |
| Effect of caffeine administration in prevention of bronchopulmonary dysplasia (BPD) | Comparison of the preventive effect of early caffeine administration with late caffeine administration in occurrence rate of bronchopulmonary dysplasia (BPD) in preterm neonates | IRCT20160827029535N8 |
| A Study in Healthy People to Test Whether BI 730357 Influences the Amount of Caffeine, Warfarin, Omeprazole, and Midazolam in the Blood | The Effect of Multiple Doses of BI 730357 on the Single Dose Pharmacokinetics of Caffeine, Warfarin, Omeprazole and Midazolam Administered Orally as a Cocktail in Healthy Subjects (an Open-label, Two-period Fixed Sequence Design Trial) | NCT04679948 |
| The Effects of Caffeine on Vestibular Evoked Myogenic Potentials in Healthy Subjects | The Effects of Caffeine on Vestibular Evoked Myogenic Potentials in Healthy | NCT01693809 |
| Effects of Neo40(TM) With Caffeine on Cycling Time Trial Performance | Effects of Neo40(TM) With Caffeine on Cycling Time Trial Performance | NCT01710761 |
| Caffeine in Amblyopia Study | | NCT02594358 |
| Estimation of the Effect of Multiple Dose Ritlecitinib (PF-06651600) on the Pharmacokinetics of a Single Dose of Caffeine in Healthy Participants | A PHASE 1, 2-PERIOD, FIXED-SEQUENCE, MULTIPLE-DOSE, OPEN-LABEL STUDY TO ESTIMATE THE EFFECTS OF RITLECITINIB (PF-06651600) ON THE PHARMACOKINETICS OF A SINGLE DOSE OF CAFFEINE IN HEALTHY PARTICIPANTS | NCT04655040 |
| A Study to Evaluate the Effect of Multiple Doses of Isavuconazole on the Pharmacokinetics of Repaglinide and Caffeine | A Phase 1 Open Label Study to Evaluate the Effect of Multiple Doses of Isavuconazole on the Pharmacokinetics of Repaglinide and Caffeine | NCT02128321 |
| A Study to Determine if Caffeine Accelerates Emergence From Anesthesia | A Randomized, Double-Blinded, Placebo-Controlled Study to Determine if Caffeine Citrate Accelerates Emergence From Anesthesia | NCT02567968 |
| Gender Difference in Response to Caffeine in Children and Adolescents | Sex and Pubertal Stage Differences in Cardiovascular Responses to Caffeine in Children | NCT02119416 |
| Caffeine and spinal anestheis related hypotension | Impact of Oral Caffeine Premedication on Maternal and Fetal OUtcomes in Elective Cesarean Delivery Under Spinal Anesthesia: A Randomized Clinical Trial | PACTR202101657899436 |
| The Effects of Caffeine on Pain-Based Pacing During a Cycling Time-Trial | The Effects of Caffeine on Pain-Based Pacing During a Cycling Time-Trial | NCT02115763 |
| To Determine Blood Concentrations of Ibuprofen and Caffeine in a Tablet Against Ibuprofen Alone From Another Tablet | A Single Center, Single Dose, Open Label, Randomized, Two Period, Two Sequence Crossover Study to Evaluate the Relative Bioavailibility of Ibuprofen From a Fixed-dose Combination Tablet Containing Ibuprofen 400 mg and Caffeine 100 mg and a Tablet of Ibuprofen 400 mg in at Least 30 Healthy Males and Females Under Fed Conditions | NCT02629354 |
| The effect of two maintenance doses of caffeine citrate 5 and 10 on premature retinopathy in very low birth weight infants | The effect of two maintenance doses of caffeine citrate 5 and 10 on premature retinopathy in very low birth weight infants | IRCT20210110049985N1 |
| Effect of Caffeine Supplementation and Personalized Insoles on Females | The Effect of Fatigue, Caffeine Supplementation and Personalized Insoles on Biomechanics and Athletic Performance in Female Adult Soccer Players. | NCT04642131 |
| Caffeine Intake and Additive Effects on Cognition | Can Caffeine Intake Combined With Aerobic Exercise Leads to Cognitive Improvement and Psychomotor Performance in Trained Individuals? | NCT02647567 |
| A clinical trial to study the effect of two drugs,caffeine & aminophylline in preterm babies with cessation of breathing due to prematurity | Comparing the efficacy ,safety and cost effectiveness of Caffeine Versus Aminophylline for Apnea of Prematurity in Indian Neonates - Prospective RCT - CAAP Trial | CTRI/2012/08/002904 |
| Ketone Production With Acute Caffeine Intake | Stimulate the Ketogenesis by Using a Caffeine Supplement | NCT02694601 |
| Study to Evaluate Effect of Belatacept on Pharmacokinetics of Inje Cocktail in Healthy Volunteers | "An Open-label, Single-sequence Study of the Effect of Belatacept on the Pharmacokinetics of Caffeine, Losartan, Omeprazole, Dextromethorphan, and Midazolam Administered as ""Inje Cocktail"" in Healthy Subjects" | NCT01766050 |
| caffeine speeds recovery from anesthesia | IMPACT OF CAFFIENE ON EMERGENCE FROM ANESTHESIA AND DISCHARGE CRITERIA IN DAY CASE SURGERIES: A PROSPECTIVE RANDOMIZED DOUBLE-BLIND PLACEBO CONTROLLED TRIAL | PACTR202101897491424 |
| Effect of Caffeine on Ileus After Laparotomy | Effect of Caffeine on Ileus After Laparotomy | IRCT20140203016473N11 |
| Cosmetic product for treating cellulite with caffeine associated with ionic liquid | Cosmetic Product for Treatment of Ginoid Hydrolipodystrophy with Caffeine Associated with Ionic Liquid | RBR-3n5ckxn |
| The Influences of Caffeine on Heart Rate Variability of Preterm Infants | The Influences of Caffeine on HRV of Preterm Infants | NCT01769118 |
| Population Pharmacokinetics of Intravenous Caffeine Citrate for Prevention of Apnoea in Preterm Infants | Population Pharmacokinetics of Intravenous Caffeine Citrate for Prevention of Apnoea in Preterm Infants | ChiCTR-OOC-16007977 |
| Early Versus Routine Caffeine Administration in Extremely Preterm Neonates | Early Versus Routine Caffeine Administration in Extremely Preterm Neonates | NCT01783561 |
| Prochlorperazine Versus Acetaminophen, Aspirin, and Caffeine for the Treatment of Acute Migraine | A Randomized, Double-blind Comparison of Single Dose Prochlorperazine Versus Acetaminophen, Aspirin and Caffeine for the Treatment of Acute Migraine in the Emergency Department. | NCT01629329 |
| To observe safety of Vasograin (a combination of Ergotamine, Paracetamol, Prochlorperazine, and Caffeine) for treating migraines in adults: an open study where all participants receive the same treatment. | To Evaluate efficacy and tolerability of Vasograin ( Ergotamine 1 mg plus Paracetamol 250 mg plus Prochlorperazine 2.5 mg plus Caffeine 100 mg) in adult patients in the treatment of acute migraine: An Open label, Non-randomized, Single arm Clinical Trial - NIL | CTRI/2024/06/068686 |
| Delayed-release Bedtime Caffeine and Sleep Inertia Symptoms Immediately Upon Awakening | Effects of a Time-delayed, Pulsatile Caffeine Formula on Sleep Inertia, Morning Cognition, Affect and Sleepiness in Healthy Volunteers | NCT04975360 |
| Pharmacokinetics in Plasma and Saliva of a Single Dose Caffeine in Healthy Volunteers | Pharmacokinetics in Plasma and Saliva of a Single Dose Caffeine in Healthy Volunteers - Caffeine PK | NL-OMON37682 |
| A DDI Study to Assess the Effect of INC280 on the PK of Midazolam and Caffeine in Patients With cMET-dysregulated Advanced Solid Tumors | A Phase I, Multicenter, Open-label, Single-sequence Drug-drug Interaction Study to Assess the Effect of INC280 on the Pharmacokinetics of Midazolam and Caffeine in Patients With cMET-dysregulated Advanced Solid Tumors | NCT02520752 |
| """WakeUp"" for Vigilance Following Lunch" | "Double Blind Placebo and Active (Caffeine) Controlled Study to Examine the Effects of 3 Doses of ""WakeUp"" Herbal Beverage Containing Green Tea (Instead of Ginkgo Biloba) on Vigilance and Function of Healthy Volunteers Following Lunch" | NCT04685005 |
| A double blind clinical trial of intravenous caffeine in accelerating awakening from total intravenous anesthesia | Effect of intravenous caffeine on accelerating awakening from total intravenous anesthesia in patients undergoing elective laparoscopic cholecystectomy | IRCT2016021725600N2 |
| Effect of Caffeine on Blood Pressure During Resistance exercise in non-athletes male | Effect of Caffeine on Blood Pressure During Resistance exercise in non-athletes male | IRCT2013012312253N1 |
| Does Caffeine Reduce Dipyridamole-Induced Protection Against Ischemia-Reperfusion Injury? | Does Caffeine Reduce Dipyridamole-Induced Protection Against Ischemia-Reperfusion Injury? | NCT00430170 |
