IMPPAT Phytochemical information: 
Dipyridamole

Dipyridamole
Clinical trials
Public title (as per ICTRP)Scientific title (as per ICTRP)Trial identifier
Efficacy and safety of Dipyridamole in Vogt-Koyanagi-Harada DiseaseEfficacy and safety of Dipyridamole in Vogt-Koyanagi-Harada DiseaseChiCTR2000030239
Post-Treatment Effects of Dipyridamole On Nucleoside Transport InhibitionPost-Treatment Effects of Dipyridamole On Nucleoside Transport Inhibition - Post-treatment dipyridamoleNL-OMON34866
"""Normal Coronary Artery"" With Slow Flow Improved by Adenosine Injection, Dipyridamole Treatment and Clinical Follow-up""""Normal Coronary Artery"" With Slow Flow Improved by Adenosine Injection, Dipyridamole Treatment and Clinical Follow-up"NCT00960817
Dipyridamole for Immune Activation in HIVA Phase I/II Pilot Study of Dipyridamole as a Modulator of Immune Activation and Systemic Inflammation in HIV-1-Infected Subjects on Antiretroviral Therapy- DAIDS-ES ID 11987NCT02121756
Dipyridamole Assessment for Flare Reduction in Systemic Lupus Erythematosus (SLE)Dipyridamole Assessment for Flare Reduction in SLENCT01781611
Pharmacokinetics of Dipyridamole Administered as Aggrenox® (Dipyridamole Extended Release Plus Aspirin) Capsule Versus Dipyridamole Immediate Release Plus Aspirin Following Alteration of Stomach pHComparison of Pharmacokinetics of Dipyridamole Administered as Aggrenox® (Dipyridamole Extended Release Plus Aspirin) Capsule Versus Dipyridamole Immediate Release Plus Aspirin Following Alteration of Stomach pH by the Prior Administration of a Proton-pump Inhibitor: An Open-label 2-way Randomized Cross-over Study in Healthy Male and Female Subjects Age 40-65.NCT02251184
A combination of prednisolone and mizoribine and a combination of prednisolone, mizoribine, warfarin and dipyridamole for IgA nephropathy with diffuse mesangial prolideration in children:A randomized controlled trial of efficacy and safetyA combination of prednisolone and mizoribine and a combination of prednisolone, mizoribine, warfarin and dipyridamole for IgA nephropathy with diffuse mesangial prolideration in children:A randomized controlled trial of efficacy and safety - A combination of prednisolone and mizoribine and a combination of prednisolone, mizoribine, warfarin and dipyridamole: A randomized controlled trial(JPIGANTS01)JPRN-C000000363
Assessment of the Efficacy of Ocular Dipyridamole in the Treatment of Dry Eye Symptomology in Subjects With PterygiumNCT02782260
Aspirin and dipyridamole effect on primary patency of arteriovenous graftsEffect of low dose aspirin and dipyridamole on primary patency of arteriovenous grafts in hemodialysis patientsTCTR20160920003
EARLY 3-months Aggrenox Treatment Started Within 24 Hrs of Ischemic Stroke Onset vs. After One Week 100 mg ASAEARLY: Prospective, Randomised, National, Multi-centre, Open-label, Blinded Endpoint Study to Compare Aggrenox b.i.d. (200 mg Dipyridamole MR + 25 mg Acetylsalicylic Acid) When Started Within 24 Hours of Stroke Onset on an Acute Stroke Unit, and Aggrenox b.i.d. When Started After a 7-day Therapy With ASA 100 mg Once Daily Outside Off an Acute Stroke Unit, in Symptomatic Ischaemic Stroke Patients Over a Three Months Treatment Period an Exploratory StudyNCT00562588
Efficacy of Allopurinol and Dypiridamole in Acute ManiaA Double-blind, Randomized, Placebo-controlled 4-week Study on the Efficacy and Safety of the Purinergic Agents Allopurinol and Dipyridamole in Acute Bipolar Mania.NCT00560079
Guided Imagery for headacheThe effect of Guided Imagery on Severity of Dipyridamole induced headache and Physiologic parameters in patients under cardiac scanIRCT2017052818550N2
A clinical trial to study the effects of dipyridamole eye drops in the patients with symptomatic ocular surface conjunctival degenerative lesions i.e. pinguecula and pterygium.A prospective randomized, double blind, placebo controlled pilot study to evaluate the safety and efficacy of topical dipyridamole in the treatment of symptomatic ocular surface conjunctival degenerative lesions i.e. pinguecula and pterygium.CTRI/2018/08/015480
Comparative assessment of the absorption of a generic formulation of aspirin/dipyridamole extended release capsule against the innovator aspirin/dipyridamole extended release capsule conducted under fasting conditions in healthy male and female volunteersA single dose, randomized, blinded, bioequivalence study of a test formulation of aspirin/dipyridamole extended release capsule in a 2 way crossover comparison against the innovator aspirin/dipyridamole extended release capsule conducted under fasting conditions in healthy male and female volunteersACTRN12614000276651
Study to Compare the Effect of a Combination of Dipyridamole With Sustained Release and Acetyl Salicylic Acid (Aggrenox®) on the Performance Relevant to Safety and on the General Condition of Healthy VolunteersPlacebo-controlled, Randomized, Double-blind Study Comparing the Effect of a Combination of 200 mg Dipyridamole With Sustained Release and 25 mg Acetyl Salicylic Acid (Aggrenox®) on the Performance Relevant to Safety and on the General Condition of Volunteers and 10 Days of Treatment Alone and in Combination With Alcohol (Study no. 591002)NCT02278302
Lexiscan(TM) Rb-82 Myocardial Perfusion PET: A Comparison With Dipyridamole StressLexiscan(TM) Rb-82 Myocardial Perfusion Positron Emission Computed Tomography: A Comparison With DipyridamoleNCT00808314
The Vascular Biology of Dipyridamole in Peripheral Arterial Disease (PAD)The Vascular Biology of Dipyridamole in Peripheral Arterial Disease (PAD)NCT00906035
The effect of dipyridamole on the pharmacokinetics of metformin.The effect of dipyridamole on the pharmacokinetics of metformin. - Met-Dipy interaction trial.EUCTR2012-000363-24-NL
Can dipyridamole induce protection against ischemia and reperfusion injury in patients undergoing elective CABG?Can dipyridamole induce protection against ischemia and reperfusion injury in patients undergoing elective CABG?EUCTR2009-014299-22-NL
Multicenter study for the treatment of Dipyridamole with novel coronavirus pneumonia (COVID-19)Multicenter study for the treatment of Dipyridamole with novel coronavirus pneumonia (COVID-19)ChiCTR2000030055
Clinical Study of Dipyridamole Tablets in the Treatment of Acute Respiratory Distress SyndromeClinical Study of Dipyridamole Tablets in the Treatment of Acute Respiratory Distress SyndromeChiCTR2300078059
Brequinar Combined With Dipyridamole in Patients With Mild to Moderate COVID-19A Phase II, Randomized, Assessor-blind, Multicenter, Multi-dose, Placebo-controlled Study Assessing the Safety and Anti-coronavirus Response of Brequinar Combined With Dipyridamole in Patients With Mild to Moderate SARS-CoV-2 Infection.NCT05166876
Study assessing the safety and anti-coronavirus response of brequinar combined with dipyridamole in patients with mild to moderate SARS-CoV-2 infectionA phase II, randomized, assessor-blind, multicenter, multi-dose, placebo-controlled study assessing the safety and anti-coronavirus response of brequinar combined with dipyridamole in patients with mild to moderate SARS-CoV-2 infection.CTRI/2021/12/038651
Clinical trial of the efficacy and safety of dipyridamole adjuvant therapy in children with IBDClinical trial of the efficacy and safety of dipyridamole adjuvant therapy in children with IBDChiCTR2100048717
Trial of Open Label Dipyridamole- In Hospitalized Patients With COVID-19A Randomized, Open-label Study of the Vascular and Microbiologic Efficacy of Dipyridamole Plus Standard Care vs. Standard Care in Hospitalized COVID19 PatientsNCT04424901
Dipyridamole to Prevent Coronavirus Exacerbation of Respiratory Status (DICER) in COVID-19Dipyridamole to Prevent Coronavirus Exacerbation of Respiratory Status (DICER) in COVID-19NCT04391179
Metformin-Dipyridamole Interaction TrialThe Effect of Dipyridamole on the Pharmacokinetics of MetforminNCT01613755
Evaluation of Dipyridamole in Preventing Post-Transplant Hypophosphatemia in Kidney Transplant RecipientsEvaluation of Dipyridamole in Preventing Post-Transplant Hypophosphatemia in Kidney Transplant RecipientsNCT06824454
A DOUBLE-BLIND? PLACEBO-CONTROLLED PARALLEL ARM TRIAL TO STUDY THE EFFICACY OF A SINGLE ORAL DOSE OF THE NUCLEOSIDE TRANSPORT INHIBITOR DIPYRIDAMOLE FOR PAIN RELIEF IN PATIENTS AFTER THIRD MOLAR SURGERY - ENT1A DOUBLE-BLIND? PLACEBO-CONTROLLED PARALLEL ARM TRIAL TO STUDY THE EFFICACY OF A SINGLE ORAL DOSE OF THE NUCLEOSIDE TRANSPORT INHIBITOR DIPYRIDAMOLE FOR PAIN RELIEF IN PATIENTS AFTER THIRD MOLAR SURGERY - ENT1EUCTR2007-000901-31-BE
Does short dipyridamole administration induce protection against ischemia-reperfusion injury?Does short dipyridamole administration induce protection against ischemia-reperfusion injury? - dipy003NL-OMON31190
Combined aspirin, clopidogrel and dipyridamole versus aspirin alone in stroke secondary prevention: a safety, tolerability and feasibility studyISRCTN83673558
The role of Dipyridamole in Improving the False Negative Rate in Pre-Operative Parathyroid Adenoma Localisation Using 99mTc SestamibiThe role of Dipyridamole in Improving the False Negative Rate in Pre-Operative Parathyroid Adenoma Localisation Using 99mTc SestamibiACTRN12605000153617
Modified-release Dipyridamole/Aspirin (200mg/25mg bd) Versus Aspirin (75mg) in Aspirin-resistant PatientsA Randomised, Crossover Study Comparing the Biochemical and Platelet Effects of Modified-release Dipyridamole/Aspirin (200mg/25 mg bd; Asasantin Retard®) With Aspirin (75 mg qd) in Coronary Artery Disease Patients With Aspirin Resistance Manifesting as Persistent Thromboxane Formation.NCT00129038
Methotrexate Plus Dipyridamole in Treating Patients With Advanced Ovarian CancerINTRAPERITONEAL METHOTREXATE AND DIPYRIDAMOLE AS SALVAGE TREATMENT FOR ADVANCED OVARIAN CARCINOMANCT00002487
S9700 Combination Chemotherapy in Treating Patients With Stage II or Stage III Pancreatic CancerA Phase II Trial of Infusional 5-Fluorouracil (5-FU), Calcium Leucovorin (LV), Mitomycin-C (Mito-C), and Dipyridamole (D) in Patients With Locally Advanced Unresected Pancreatic AdenocarcinomaNCT00003018
Comparison of Pharmacokinetics of Dipyridamole in Asasantin Extended Release (ER) and in a Combination of Persantin Immediate Release Tablets and ASA Tablets in Healthy SubjectsComparison of Pharmacokinetics of Dipyridamole in Asasantin Extended Release (ER) 200/25 mg Capsules Bid and in a Combination of Persantin Immediate Release Tablets (100 mg Qid) and ASA Tablets (25 mg Bid) in an Open, Randomized, 2-way Crossover Study in Healthy SubjectsNCT02273505
The Effects of Oral Dipyridamole Treatment on the Innate Immune Response During Human EndotoxemiaThe Effects of Oral Dipyridamole Treatment on the Innate Immune Response During Human Endotoxemia.NCT01091571
Comparison between Dipyridamole and Adenosine infusion in the evaluation of intermediate coronary restrictions (stenoses) in the cardiac catheterization laboratorY.Dipyridamole versus Adenosine infusion in the physiologic assessment of Intermediate coronary Stenoses in the cardiac catheterization laboratorY - DAISYEUCTR2010-024485-21-IT
Effect of Ticagrelor vs. Dipyridamole on Adenosine UptakeTicagrelor and Adenosine Uptake. Phase II Study Comparing the Effects of Ticagrelor vs Dipyridamole on Adenosine UptakeNCT01690884
Prospective, randomized, national, multi-centre, open-label, blinded endpoint study to compare Aggrenox® b.i.d. (200 mg dipyridamole MR + 25 mg acetylsalicylic acid) when started within 24 hours of stroke onset on an acute stroke unit, and Aggrenox® b.i.d. when started after a 7-day therapy with ASA 100 mg once daily outside off an acute stroke unit, in symptomatic ischaemic stroke patients over a three months treatment period (EARLY) – An exploratory studyGerman title:Prospektive, randomisierte, nationale, offene Multicenterstudie mit verblindeter Endpunktanalyse zum Vergleich von Aggrenox® Retardkapseln (200 mg Dipyridamol + 25 mg Acetylsalicylsäure) 2x täglich, Behandlungsbeginn innerhalb von 24 Stunden nach einem ischämischem Schlaganfall auf einer Stroke unit, versus Aggrenox® Retardkapseln b.i.d., Behandlungsbeginn außerhalb einer Stroke unit nach einer 7-tägigen Therapie mit 100 mg Acetylsalicylsäure pro Tag bei symptomatischen Patienten für einen Behandlungszeitraum von drei Monaten (EARLY) – Phase IV Studie - EARLYProspective, randomized, national, multi-centre, open-label, blinded endpoint study to compare Aggrenox® b.i.d. (200 mg dipyridamole MR + 25 mg acetylsalicylic acid) when started within 24 hours of stroke onset on an acute stroke unit, and Aggrenox® b.i.d. when started after a 7-day therapy with ASA 100 mg once daily outside off an acute stroke unit, in symptomatic ischaemic stroke patients over a three months treatment period (EARLY) – An exploratory studyGerman title:Prospektive, randomisierte, nationale, offene Multicenterstudie mit verblindeter Endpunktanalyse zum Vergleich von Aggrenox® Retardkapseln (200 mg Dipyridamol + 25 mg Acetylsalicylsäure) 2x täglich, Behandlungsbeginn innerhalb von 24 Stunden nach einem ischämischem Schlaganfall auf einer Stroke unit, versus Aggrenox® Retardkapseln b.i.d., Behandlungsbeginn außerhalb einer Stroke unit nach einer 7-tägigen Therapie mit 100 mg Acetylsalicylsäure pro Tag bei symptomatischen Patienten für einen Behandlungszeitraum von drei Monaten (EARLY) – Phase IV Studie - EARLYEUCTR2006-004870-28-DE
Phase II Study for the Diagnosis and Functional Assessment of CAD Using Transthoracic-EchodopplerPhase 2, Monocentric, Single Blind Study, Comparing the Efficacy and Tolerance of a Dipyridamole/Adenosine Combination Given Intravenously, as a Slow Bolus and at Low Doses to Adenosine Alone for Coronary Flow Reserve Assessment (in Patients With Stable Ischemic Heart Disease) Using Transthoracic EchodopplerNCT01593644
The effects of oral dipyridamole treatment on the innate immune response during human endotoxemia.The effects of oral dipyridamole treatment on the innate immune response during human endotoxemia. - Effects of dipyridamole on innate immune response during human endotoxemia.NL-OMON34679
Etude clinique de phase II, monocentrique, en simple aveugle comparant l'efficacité et la tolérance de l'administration intraveineuse de dipyridamole et d'adénosine donnés séquentiellement ou de façon concomitante à faible doses, à l'adénosine seule donnée à la dose standard usuelle, dans l'évaluation de l'ischémie myocardique par scintigraphie au technetium sestamibi. - non applicableEtude clinique de phase II, monocentrique, en simple aveugle comparant l'efficacité et la tolérance de l'administration intraveineuse de dipyridamole et d'adénosine donnés séquentiellement ou de façon concomitante à faible doses, à l'adénosine seule donnée à la dose standard usuelle, dans l'évaluation de l'ischémie myocardique par scintigraphie au technetium sestamibi. - non applicableEUCTR2006-005750-68-FR
Comparative assessment of the absorption of a generic formulation of aspirin/dipyridamole extended release capsule against the innovator aspirin/dipyridamole extended release capsule conducted under fed conditions in healthy male and female volunteersA single dose, randomized, blinded, bioequivalence study of a test formulation of aspirin/dipyridamole extended release capsule in a 2 way crossover comparison against the innovator aspirin/dipyridamole extended release capsule conducted under fed conditions in healthy male and female volunteersACTRN12614000275662
Is intensive blood thinning with three antiplatelet drugs better than the current guideline treatment in reducing recurrence after acute stroke?Safety and efficacy of clopidogrel when added to aspirin and dipyridamole in high risk patients with recent ischaemic stroke or TIA: a randomised controlled trial - TARDISEUCTR2007-006749-42-GB
Dipyridamole/Magnesium To Improve Sickle Cell HydrationDipyridamole/Magnesium To Improve Sickle Cell HydrationNCT00276146
Enhancement of Postocclusive Reactive Hyperaemia by DipyridamoleEnhancement of Postocclusive Reactive HyperaemiaNCT00268554
Dipyridamol opbouw in secundaire preventie van beroerte.A prospective randomised open label study to determine the best dose escalation schema of dipyridamole added to acetylsalicylic acid, based on the side-effect headache, in patients starting secondary preventive therapy for stroke.NL-OMON24084
Does a Seven Day Treatment With Dipyridamole Induce Protection Against Ischemia-Reperfusion Injury?Does a Seven Day Treatment With Dipyridamole Induce Protection Against Ischemia-Reperfusion Injury?NCT00457405
Does Caffeine Reduce Dipyridamole-Induced Protection Against Ischemia-Reperfusion Injury?Does Caffeine Reduce Dipyridamole-Induced Protection Against Ischemia-Reperfusion Injury?NCT00430170
A combination of prednisolone, warfarin and dipyridamole for IgA nephropathy with diffuse mesangial proliferation in children.A combination of prednisolone, warfarin and dipyridamole for IgA nephropathy with diffuse mesangial proliferation in children. - A combination of prednisolone, warfarin and dipyridamole for IgA nephropathy with diffuse mesangial proliferation in children.JPRN-C000000374
Placebo controlled,randomised,crossover study of the efficacy of dipyridamole in the management of angina in patients with Coronary Slow Flow PhenomenonPlacebo controlled, randomised, crossover study of the efficacy of dipyridamole in reducing the number of angina episodes in patients with Coronary Slow Flow Phenomenon (CSFP)ACTRN12606000236594
Clinical Trial of Dipyridamole in SchizophreniaClinical Trial of Dipyridamole in SchizophreniaNCT00349973
A combination of prednisolone, mizoribine, warfarin and dipyridamole for IgA nephropathy with nephrotic syndrome and diffuse mesangial proliferation in children.A combination of prednisolone, mizoribine, warfarin and dipyridamole for IgA nephropathy with nephrotic syndrome and diffuse mesangial proliferation in children. - A combination of prednisolone, mizoribine, warfarin and dipyridamole for IgA nephropathy with nephrotic syndrome and diffuse mesangial proliferation in children.JPRN-C000000375
Does caffeine reduce dipyridamole-induced protection against ischemia-reperfusion injury?Does caffeine reduce dipyridamole-induced protection against ischemia-reperfusion injury? - dipy001NL-OMON30237