IMPPAT Phytochemical information: 
Epigallocatechin gallate

Epigallocatechin gallate
Clinical trials
Public title (as per ICTRP)Scientific title (as per ICTRP)Trial identifier
The Effect of?GTT-EGCG?on Acne WomenThe Effect of?GTT-EGCG?on Acne WomenNCT01846338
Effects of epigallocatechin gallate (EGCG) and Cissus Quadrangularis extract on adiposity, metabolic profiles, serum leptin, and resting metabolic rateEffects of epigallocatechin gallate (EGCG) and Cissus Quadrangularis extract on adiposity, metabolic profiles, serum leptin, and resting metabolic rateTCTR20200422001
Effects of glutamine and epigallocatechin-3-gallate on glucose tolerance, markers of inflammation, oxidative stress and procoagulant status in Type 2 diabetes mellitusEffects of glutamine and epigallocatechin-3-gallate on glucose tolerance, markers of inflammation, oxidative stress and procoagulant status in Type 2 diabetes mellitus - Glutamine and EGCG in type 2 diabetes mellitusNL-OMON38189
Improvement of Endothelial Function by EGCGThe Role of EGCG in Different Application Forms on Flow-mediated Dilation in Healthy VolunteersNCT01662232
Epigallocatechingallate (EGCG) in Cardiac AL AmyloidosisA Phase II Open-label Randomized Study of Dietary Supplement With Epigallocatechin Gallate (EGCG) to Improve Cardiac Dysfunction in Patients With AL Amyloidosis Who do Not Require Chemotherapy (EpiCardiAL)NCT01511263
EGCG Improves Acne by Modulating Molecular TargetsEpigallocatechin-3-Gallate Improves Acne in Humans by Modulating Intracellular Molecular Targets and Inhibiting P. AcnesNCT01687556
Collagen-targeted Positron Emission Tomography (PET) Imaging for Assessment of EGCG EffectCollagen-targeted PET Imaging for Assessment of EGCG EffectNCT06265532
SUNIMUD - Sunphenon EGCg (Epigallocatechin-Gallate) in Duchenne Muscular DystrophySUNIMUD - Sunphenon EGCg (Epigallocatechin-Gallate) in Duchenne Muscular Dystrophy - SUNIMUDEUCTR2009-016482-28-DE
Effects of Epigallocatechin Gallate (EGCG) in Healthy, Young AdultsCerebral Blood Flow, Cerebro-electrical Activity and Behavioural Effects of Epigallocatechin Gallate (EGCG) Administration in Healthy, Young AdultsNCT00981292
Study of Oral Epigallocatechin-3-gallate (EGCG) in IPF PatientsDose Ranging Study of Oral Epigallocatechin-3-gallate (EGCG) Given Daily for 12 Weeks to Patients With Idiopathic Pulmonary Fibrosis (IPF) Evaluating Safety, PK Interactions With Standard of Care Drugs, and Biomarkers of Drug EffectNCT05195918
Sunphenon EGCg (Epigallocatechin-Gallat) in the early stage of Alzheimer´s Disease - SUN-AKSunphenon EGCg (Epigallocatechin-Gallat) in the early stage of Alzheimer´s Disease - SUN-AKEUCTR2009-009656-20-DE
Sunphenon in Progressive Forms of Multiple SclerosisMonocentric, Prospective, Doubleblind, Randomised/Stratified, Placebocontrolled Two-arm Study to Evaluate the Effect of Sunphenon EGCg (Main Component Epigallocatechin-Gallat) on the Increase of Brain Atrophy in the Cerebral Magnetic Resonance Tomography in a 36-months Treatment Time in Patients With Primary or Secondary Chronic-progressive Multiple SclerosisNCT00799890
Reducing Frailty for Older Cancer Survivors Using SupplementsReducing Frailty for Older Cancer Survivors Using Supplements (ReFOCUS): A Phase 2 Randomized Controlled Trial of Epigallocatechin-3-Gallate (EGCG) on Frailty and Inflammation in Older Survivors of CancerNCT04553666
Effect of EGCG on the Body's Response to InsulinAn Exploratory Study to Evaluate the Ability of Epigallocatechin Gallate to Simultaneously Improve Metabolic and Cardiovascular Actions of Insulin in Healthy and Obese SubjectsNCT00434499
The Effect of the Association EGCG, Folic Acid and Vitamin B12 in Preventing the Persistence of HPV Infection.A Pilot Study to Test the Effect of the Association of Epigallocatechin Gallate (EGCG), Folic Acid and Vitamin B12 in Preventing the Persistence of Human Papilloma Virus (HPV) Infection.NCT06285357
Pharmacokinetics and Hepatic Safety of EGCGPharmacokinetics and Hepatic Safety of EGCGNCT04177693
Skin Evaluation of Turmeric/EGCG Emulgel for Skin Irritation and Sensitization Effects in Healthy ParticipantsSkin Evaluation of Turmeric/EGCG Emulgel for Skin Irritation and Sensitization Effects in Healthy ParticipantsTCTR20250317007
A phase III randomized controlled clinical trial of EGCG, a green tea extract, in the prevention of acute radiation-induced intestinal injuryA phase III randomized controlled clinical trial of EGCG, a green tea extract, in the prevention of acute radiation-induced intestinal injuryChiCTR2500101198
Green Tea, High in Epigallocatechin Gallate (EGCG) and Postprandial Fat OxidationEffects of the Green Tea Extract TEAVIGO High in EGCG, on Postprandial Fat Oxidation in Overweight VolunteersNCT00867555
"""Using Epigallocatechin Gallate (EGCG) and Cognitive Training to Modulate Cognitive Performance in Patients With Fragile X Syndrome"" (TESFX)"Estrogen Receptors Beta (ER-B) as Therapeutic Targets for the Improvement of Cognitive Performance in Fragile-X (TESXF)NCT01855971
Double blind, randomised, prospective placebo controlled parallel group phase III study to investigate the Effect of EGCG supplementation on disease progression of patients with Multiple System Atrophy (MSA)Double blind, randomised, prospective placebo controlled parallel group phase III study to investigate the Effect of EGCG supplementation on disease progression of patients with Multiple System Atrophy (MSA) - Progression Rate of MSA under EGCG Supplementation as anti-Aggregation-ApproachEUCTR2012-000928-18-DE
Effect of Green Tea on Methadone Maintenance PatientsThe effect of green tea enriched with EGCG on some inflammatory, antioxidant and cognitive factors in methadone maintenance patients; Triple-blind clinical trialIRCT20180902040927N5
A prospective phase II trial of EGCG for treatment of acute radiation-induced intestinal injuryA prospective phase II trial of EGCG for treatment of acute radiation-induced intestinal injuryChiCTR2100053703
Phase II clinical study of EGCG in preventing radiation oral mucositisPhase II clinical study of EGCG in preventing radiation oral mucositisChiCTR2100052871
Epigallocatechin as an immunomodulatory and antineoplastic treatment in elderly patients with acute leukemia or mielodysplasiaEpigallocatechin (EGCG) as an immunomodulatory and antineoplastic treatment in elderly patients with AML or high-risk MDS inelegible for high-dose conventional chemotherapyRBR-3nvjx2k
Effect of Green Tea on StrokeThe effect of powdered green tea enriched with epigallocatechin gallate (EGCG) on some clinical, biochemical, inflammatory, antioxidant and cognitive parameters in stroke patients; a double-blind, placebo-controlled clinical trialIRCT20180902040927N1
Randomized Clinical Trial: IS Zinc and Zinc Ionophere EGCG as Supplement Improve Outcome of Active Pulmonary TuberculosisRandomized Clinical Trial: IS Zinc and Zinc Ionophere EGCG as Supplement Improve Outcome of Active Pulmonary TuberculosisNCT05116098
Epigallocatechin-3-gallate (EGCG) in supportive and symptomatic treatment of patients with esophageal cancerEpigallocatechin-3-gallate (EGCG) in supportive and symptomatic treatment of patients with esophageal cancerChiCTR2100050444
The acute effects of a green tea extract, -Epigallocatechin Gallate (EGCG) on cognition, stress, brain function and cardiovascular function.An investigation into the acute effects of -Epigallocatechin Gallate (EGCG) on cognition, stress, brain function and cardiovascular function in healthy adults.ACTRN12609000646246
Study of Epigallocatechin-3-gallate (EGCG) for Supportive and Symptomatic Management in Patients With Esophageal CancerStudy of Epigallocatechin-3-gallate (EGCG) for Supportive and Symptomatic Management in Patients With Esophageal CancerNCT05039983
Oxygen Atomizing Inhalation of EGCG in the Treatment Interstitial Pneumonia in Cancer PatientsOxygen Atomizing Inhalation of EGCG in the Treatment Interstitial Pneumonia in Cancer Patients: Phase I-II Clinical TrialNCT05758571
The adjunctive use of (-)-epigallocatechin gallate (EGCG) subgingival irrigating solution with scaling and root planing in the management of chronic periodontitisThe adjunctive use of (-)-epigallocatechin gallate (EGCG) subgingival irrigating solution with scaling and root planing in the management of chronic periodontitisChiCTR2000029831
Comparison of the tear level between (-)-epigallocatechin gallate (EGCG) and (-)-epigallocatechin 3-O-(3-O-methyl) gallate (EGCG3"Me) after oral administration in healthy volunteers.Comparison of the tear level between (-)-epigallocatechin gallate (EGCG) and (-)-epigallocatechin 3-O-(3-O-methyl) gallate (EGCG3"Me) after oral administration in healthy volunteers. - Comparison of the tear level in green tea catechins after oral administration in healthy volunteers.JPRN-UMIN000034291
The effect of powdered green tea in patients with coronary artery diseaseThe effect of powdered green tea enriched with epigallocatchin gallate (EGCG) on some clinical, electrophysiological, biochemical, inflammatory and antioxidant parameters in patients with coronary artery disease, a randomized, triple blind clinical trialIRCT20181203041835N1
Chemopreventive Effects of Epigallocatechin Gallate (EGCG) in Colorectal Cancer (CRC) PatientsA Pilot Study to Evaluate the Chemopreventive Effects of Epigallocatechin Gallate (EGCG) in Colorectal Cancer (CRC) Patients with Curative Resections.NCT02891538
A randomized, blank controlled, open clinical study of EGCG in patients with non-alcoholic fatty liver diseaseEGCG inhibits the interaction between DPP4 and PRDM10 to improve the occurrence and development of non-alcoholic fatty liver disease and its mechanismChiCTR2300076741
Effect of the use of a catechin from green tea on the clinical performance of adhesives for dental restorationsEffect of epigallocatechin-3-gallate (EGCG) in the clinical performance of an universal adhesive system: a randomized clinical study.RBR-2hr94r
Study of Epigallocatechin-3-gallate (EGCG) for Esophagus Protection in Patients With Lung Cancer Receiving Radial RadiotherapyNCT02577393
Effect of a Green Tea's Catechin on Appetite in healthy womenEffects of Acute Supplementation with Epigalocatequine 3 Galate (EGCG) on Appetite's Modulation in healthy womenRBR-9svwrv
Study of Epigallocatechin-3-gallate (EGCG) for Skin Prevention in Patients With Breast Cancer Receiving Adjuvant RadiotherapyPhase II Study of Topical Epigallocatechin-3-gallate (EGCG) in Patients With Breast Cancer Receiving Adjuvant RadiotherapyNCT02580279
Prevention of Cognitive Decline in ApoE4 Carriers With Subjective Cognitive Decline After EGCG and a Multimodal InterventionPrevention of Cognitive Decline in ApoE4 Carriers With Subjective Cognitive Decline After EGCG and a Multimodal InterventionNCT03978052
Pediatric Exploratory Research Study of EGCG Use and Safety (PERSEUS)Pediatric Exploratory Research Study of EGCG Use and Safety (PERSEUS)NCT03624556
Study of of Oxygen Nebulized Inhalation EGCG in Cancer Patients With New Coronary PneumoniaStudy of of Oxygen Nebulized Inhalation EGCG in Cancer Patients With New Coronary:Phase II Clinical TrialNCT06924749
Curcumin and EGCG Supplementation to Improve Serum BDNF and Mood DisturbanceA Randomized Controlled Trial to Determine the Effects of Curcumin and Epigallocatechin Gallate Supplementation on Serum Brain Derived Neurotrophic Factor and Mood Disturbance in AdultsNCT06531863
Reducing Frailty for Older Cancer Survivors Using Supplements IIA Phase 2 Randomized Controlled Trial of Epigallocatechin-3-Gallate (EGCG) on Frailty and Inflammation in Older Survivors of CancerNCT06068543
Epigallocatechin Gallate (EGCG) to Improve Cognitive Performance in Foetal Alcohol Syndrome (FAS) ChildrenEpigallocatechin Gallate (EGCG) as Therapeutic Tool to Improve Cognitive Performance in Foetal Alcohol Syndrome (FAS) ChildrenNCT02558933
Green Tea Extract in Treating Patients With Nonmetastatic Bladder CancerA Phase II Randomized, Placebo-Controlled Trial of Polyphenon E to Evaluate Bladder Tissue Levels of EGCGNCT00666562
Epstein-Barr Virus Reactivation and the Effect of EGCG on Virus Reactivation in Remission PatientsStudy of Epstein-Barr Virus Reactivation and the Effect of Dietary Supplement Epigallocatechin Gallate (EGCG) on Virus Reactivation in Remission Patients With Nasopharyngeal Carcinoma - A Randomized TrialNCT01744587
Egcg, a dyrk1a Inhibitor as Therapeutic Tool for Reversing Cognitive Deficits in Down Syndrome Individuals.Egcg, a dyrk1a Inhibitor as Therapeutic Tool for Reversing Cognitive Deficits in Down Syndrome Individuals.NCT01394796
Effects of EGCG (Epigallocatechin Gallate) in Chorea HuntingtonEffects of EGCG (Epigallocatechin Gallate) in Chorea Huntington - ETONEUCTR2010-023941-31-DE
Sunphenon Epigallocatechin-Gallate (EGCg) in Duchenne Muscular DystrophySunphenon Epigallocatechin-Gallate (EGCg) in Duchenne Muscular DystrophyNCT01183767
Sunphenon EGCg (Epigallocatechin-Gallate) in the Early Stage of Alzheimer´s DiseaseSunphenon EGCg (Epigallocatechin-Gallate) in the Early Stage of Alzheimer´s DiseaseNCT00951834
Efficacy and Safety Study of EGCG/Tocotrienol in 18 Patients With Splicing-mutation-mediated Cystic Fibrosis (CF)Single-site, Open-label, Dose-ranging, Efficacy, and Safety Study of EGCG/Tocotrienol in 18 Patients With Splicing-mutation-mediated CFNCT00889434
Evaluation of Oral EGCG Treatment for L-SIL Associated With HPV InfectionEvaluation of Oral Epigallocatechin Gallate Treatment for Low-grade Cervical Lesions (L-SIL) Associated With Human Papilloma Virus (HPV) InfectionNCT06314113
Epigallocatechin Gallate (EGCG) as a Flushing Agent During Full Pulpotomy in Mature Permanent Molars With Irreversible PulpitisThe Influence of Epigallocatechin Gallate (EGCG) as a Flushing Agent During Full Pulpotomy Using Two Different Calcium Silicate-based Materials on Postoperative Pain and Success Rate in Mature Permanent Molars With Irreversible Pulpitis: A Randomized Clinical TrialNCT05811403
EGCG for the Prevention and Treatment of TIPNClinical Study of EGCG for the Prevention and Treatment of Peripheral Neuropathy Induced by Taxane (TIPN)NCT06524609
Comparative Evaluation of Nanohydroxyapatite & EGCG mix versus Biodentine for Indirect Pulp Therapy in Young Permanent TeethComparative Evaluation Of Indirect Pulp Therapy In Young Permanent Teeth Using Nanohydroxyapatite And Epigallocatechin-3-Gallate (EGCG) Mix Versus Biodentine: A Randomized Controlled Trial - NILCTRI/2025/03/082145
EGCG for Hepatocellular Carcinoma ChemopreventionPhase II Randomized Controlled Trial of Epigallocatechin Gallate for Hepatocellular Carcinoma ChemopreventionNCT06015022
Efficacy of a maintenance therapy with supplements containing indole-3-carbinol (I3C) and epigallocatechin-3-gallate (EGCG) in ovarian cancer patientsAn open randomized controlled clinical trial to evaluate the efficacy of a maintenance therapy with supplements containing I3C and EGCG in ovarian cancer patientsACTRN12616000394448
Green Tea Extract in Treating Patients With Monoclonal Gammopathy of Undetermined Significance and/or Smoldering Multiple MyelomaThe Clinical and Biologic Evaluation of Polyphenon E, an Extract of Green Tea Containing EGCG, in Plasma Cell Dyscrasias - Pilot StudyNCT00942422