| In Vivo Assessment of Histamine Pharmacodynamics | In Vivo Functional Assessment of Histamine Pharmacodynamics in Children | NCT00809692 |
| Apitox, Honeybee Toxin for Pain and Inflammation of Osteoarthritis | A Multicenter, Randomized, Double Blind, Active Controlled, Parallel Group, Clinical Study, to Evaluate the Safety and Efficacy of Apitox vs Histamine in Subjects With Refractory Osteoarthritis Pain and Inflammation of the Knee | NCT01112722 |
| A clinical trial to determine the effects of an oral anti-histamine drug on nocturnal scratching behavior in atopic dermatitis patients | A clinical trial to determine the effects of an oral anti-histamine drug on nocturnal scratching behavior in atopic dermatitis patients - Nocturnal scratching behavior in atopic dermatitis patients | JPRN-UMIN000003424 |
| Efficacy of N-Alpha Methyl Histamine versus Propranolol in prevention of miigraine. | Efficacy of N alpha Methyl histamine versus propranolol in migraine prophylaxis | ACTRN12610000126011 |
| A Study to Assess the Effects of Remission Maintenance Therapy with Ceplene®, Given with Low-Dose Interleukin-2 (IL-2, Proleukin®), on Immune Response and Minimal Residual Disease (MRD) in Adult Patients with Acute Myeloid Leukemia (AML) in First Complete Remission (CR1) | An Open-Label, Multicenter Study of the Effects of Remission Maintenance Therapy with Ceplene® (Histamine Dihydrochloride), Given in Conjunction with Low-Dose Interleukin-2 (IL-2, Proleukin®), on Immune Response and Minimal Residual Disease (MRD) in Adult Patients with Acute Myeloid Leukemia (AML) in First Complete Remission (CR1) | EUCTR2009-012083-14-GB |
| A Study to Assess the Effects of Remission Maintenance Therapy with Ceplene®, Given with Low-Dose Interleukin-2 (IL-2, Proleukin®), on Immune Response and Minimal Residual Disease (MRD) in Adult Patients with Acute Myeloid Leukemia (AML) in First Complete Remission (CR1) | An Open-Label, Multicenter Study of the Effects of Remission Maintenance Therapy with Ceplene® (Histamine Dihydrochloride), Given in Conjunction with Low-Dose Interleukin-2 (IL-2, Proleukin®), on Immune Response and Minimal Residual Disease (MRD) in Adult Patients with Acute Myeloid Leukemia (AML) in First Complete Remission (CR1) | EUCTR2009-012083-14-SE |
| Interleukin-2 With or Without Histamine Dihydrochloride in Treating Patients With Metastatic Kidney Cancer | A Randomized Phase II Study to Evaluate the Efficacy of Combined Immunotherapy With Subcutaneous Interleukin-2 and Maxamine in Patients With Metastatic Renal Cell Carcinoma | NCT00005038 |
| A randomised controlled placebo based trial to determine the efficacy of a prophylactic dose of hydrocortisone and anti histamine in preventing reactions to anti snake venom (ASV) | | ISRCTN29425449 |
| Assessment of changes in ventilation following induced bronchoconstriction with inhaled histamine in normal subjects using Krypton-81m ventilation scintigraphy | Assessment of changes in ventilation following induced bronchoconstriction with inhaled histamine in normal subjects using Krypton-81m ventilation scintigraphy | ISRCTN70267623 |
| Interleukin-2 With or Without Histamine Dihydrochloride in Treating Patients With Stage IV Melanoma Metastatic to the Liver | A Phase III, Multi-Center Controlled Trial With Stratified Randomization Comparing The Efficacy Of Interleukin-2 (IL-2) Plus Histamine Dihydrochloride (HDC) Versus IL-2 Alone To Increase The Duration Of Survival In Patients With AJCC Stage IV Malignant Melanoma With Hepatic Metastasis | NCT00039234 |
| BIOLOGICAL STANDARDISATION OF ALLERGENIC EXTRACTS OF MITES TO DETERMINE BIOLOGICAL ACTIVITY (IN HEP UNITS) IN SENSITIVISED PATIENTS. | BIOLOGICAL STANDARDISATION OF ALLERGENIC EXTRACTS OF MITES (Dermatophagoides pteronyssinus, Dermatophagoides farinae, Blomia tropicalis and Lepidoglyphus destructor) TO DETERMINE BIOLOGICAL ACTIVITY IN HISTAMINE EQUIVALENT UNITS (HEP) IN SENSITIVISED PATIENTS. - DIA-STA04080912-0124 | CTIS2024-513834-40-01 |
| Interleukin-2 Plus Histamine Dihydrochloride in Treating Patients With Acute Myeloid Leukemia | Multi-Center, Randomized Open-Label Study to Evaluate the Safety and Efficacy of Immunotherapy With Subcutaneous Maxamine (Histamine Dihydrochloride) Plus Proleukin (Interleukin-2) Versus No Treatment (Standard of Care) in Patients With Acute Myeloid Leukemia in First or Subsequent Complete Remission (CR) | NCT00003991 |
| Evaluation of Histamine, CGRP and VIP as Markers for Activation of Trigeminal and Parasympathetic Nerve Fibers | "Evaluation of Histamine, CGRP and VIP as Biological Markers for Activation of Trigeminal and Parasympathetic Nerve Fibers in Response to ""Sinus"" Symptoms" | NCT00208065 |
| Study to Evaluate the Effect of the Coadministration of SCH 497079 (a Histamine 3 [H3] Receptor Antagonist) Plus Desloratadine on Nasal Congestion in Subjects With Seasonal Allergic Rhinitis Who Have Been Exposed to Pollen in the Vienna Challenge Chamber (VCC) - H3 POC | Study to Evaluate the Effect of the Coadministration of SCH 497079 (a Histamine 3 [H3] Receptor Antagonist) Plus Desloratadine on Nasal Congestion in Subjects With Seasonal Allergic Rhinitis Who Have Been Exposed to Pollen in the Vienna Challenge Chamber (VCC) - H3 POC | EUCTR2004-001883-39-AT |
| A Trial of Camrelizumab Plus Nab-paclitaxel and Levocetirizine in Metastatic or Recurrent TNBC | Camrelizumab Plus Nab-paclitaxel and Anti-histamine Drug Levocetirizine in Metastatic or Recurrent Triple-negative Breast Cancer: a Randomized, Double-arm, Phase 2 Randomized Controlled Trial | NCT06632405 |
| Relationship between sensory qualities and emotions (itch induction by means of histamine-iontophoresis) | Relationship between sensory qualities and emotions (itch induction by means of histamine-iontophoresis) - JRS-H | DRKS00005381 |
| Effects of High-concentration Topical Capsaicin on Histaminergic and Non-histaminergic Itch | The Role of Pre-established Skin Inflammation on the Susceptibility to Histamine and Cowhage-induced Itch in Healthy Humans | NCT02769910 |
| ALAP-1 for the attenuation of nasal provocation with histamine in seasonal allergic rhinitis: a randomised, double-blind, placebo-controlled, three-day dosing, cross-over study and dose finding one month cross-over study | | ISRCTN83077547 |
| The Impact of Dietary Histamine in Chronic Pain – Pilot Study | Assessing the impact of an exogenous histamine-reducing dietary intervention on pain as measured by the Brief Pain Inventory (BPI) in adults. | ACTRN12624000643572 |
| Effects of mometazone furoate hydrate on up-regulation of histamine H1 receptor mRNA in the nasal mucosa induced by artificial exposure of Japanese cedar pollen in patients with allergic rhinitis to cedar pollen. | Effects of mometazone furoate hydrate on up-regulation of histamine H1 receptor mRNA in the nasal mucosa induced by artificial exposure of Japanese cedar pollen in patients with allergic rhinitis to cedar pollen. - Effects of mometazone furoate hydrate on up-regulation of histamine H1 receptor mRNA in the nasal mucosa induced by artificial exposure of Japanese cedar pollen in patients with allergic rhinitis to cedar pollen. | JPRN-UMIN000008952 |
| Assessment of the effects of topical sodium cromoglicate on itch and flare in human skin | To assess the effects of topical sodium cromoglicate on itch and flare in human skin induced by intradermal histamine: a randomised double-blind vehicle controlled intra-subject design trial | ISRCTN35671014 |
| Dietary Treatment for Chronic Urticaria | Can Low Histamine Diet Reduce Symptoms of Patients With Idiopathic Urticaria? | NCT02047136 |
| To determine the minimum amount of Alternaria alternata allergenextract producing a positive skin reaction. | Biological standardization of Alternaria alternata allergen extract todetermine the biological activity in histamine equivalent units (HEP). | EUCTR2013-001308-13-ES |
| Proton Pump Inhibitor Versus Histamine-2 Receptor Antagonist for the Prevention of Recurrent Peptic Ulcers | Pantoprazole Versus Famotidine for the Prevention of Recurrent Peptic Ulcers in Thienopyridine Users - a Double-blind Randomized Controlled Trial | NCT02551744 |
| Proton Pump Inhibitors vs. Histamine-2 REceptor Blockers for Ulcer Prophylaxis Therapy in the Intensive Care Unit | A multi-centre, cluster randomised, crossover, registry trial comparing the safety and efficacy of proton pump inhibitors with histamine-2 receptor blockers for ulcer prophylaxis in intensive care patients requiring invasive mechanical intervention. | ACTRN12616000481471 |
| A study to evaluate safety and efficiency of treatment with histamine andinterleukin-2 in chronic myelomonocytic leukemia (CMML) | Safety, Efficacy and Immune Response of Histamine Dihydrochloride andLow-dose Interleukin-2 in Chronic Myelomonocytic Leukemia (CMML) | EUCTR2014-004874-41-SE |
| The examination of the effect of intranasal anti-histamine on intranasal corticosteroid in Japanese cedar pollinosis | The examination of the effect of intranasal anti-histamine on intranasal corticosteroid in Japanese cedar pollinosis - The examination of the effect of intranasal anti-histamine on intranasal corticosteroid in Japanese cedar pollinosis | JPRN-UMIN000025508 |
| The effect of histamine on acethylcholine-mediated sweating | The effect of histamine on acethylcholine-mediated sweating - The effect of histamine on sweating | JPRN-UMIN000010077 |
| Effect of anti-histamine and oral corticosteroid for symptoms in oral food challenge | Effect of anti-histamine and oral corticosteroid for symptoms in oral food challenge - Anti-histamine and oral corticosteroid for symptoms in OFC | JPRN-UMIN000033584 |
| Dermal Blood Flow Response to Escalating Doses of Histamine, Administered by a Skin Prick | Dermal Blood Flow Response to Escalating Doses of Histamine, Administered by a Skin Prick | NCT04399213 |
| A Multicenter, Randomized, Double-blind, Placebo-Controlled Parallel Study:Clinical Study of Efficacy and Safety of Histamine Human Immunoglobulin (ShuYangMinNing) in the Treatment of Chronic Spontaneous Urticaria (CSU) | A Multicenter, Randomized, Double-blind, Placebo-Controlled Parallel Study:Clinical Study of Efficacy and Safety of Histamine Human Immunoglobulin (ShuYangMinNing) in the Treatment of Chronic Spontaneous Urticaria (CSU) | ChiCTR2400081126 |
| Role of the Central Nervous System in Allergic Rhinitis | Role of the Central Nervous System in Allergic Rhinitis: Activation of Different Brain Regions After a Nasal Histamine Provocation in Healthy and Allergic Patients | NCT01777464 |
| A randomized, single-blind, saline-controlled, dose-finding, study to characterize the pruritus and inflammatory response to intradermal histamine in healthy volunteers and patients with atopic dermatitis | A randomized, single-blind, saline-controlled, dose-finding, study to characterize the pruritus and inflammatory response to intradermal histamine in healthy volunteers and patients with atopic dermatitis - Characterization of a pruritus challenge model | NL-OMON54996 |
| SCS in Itch | The effect of spinal cord stimulation and dorsal root ganglion stimulation on histamine induced itch: an experimental pilot study. | NL-OMON23833 |
| The effect of spinal cord stimulation and dorsal root ganglion stimulation on histamine induced itch: an experimental pilot study | The effect of spinal cord stimulation and dorsal root ganglion stimulation on histamine induced itch: an experimental pilot study - SCS in itch | NL-OMON49164 |
| Inter-arm and Inter-period Reproducability of the Dermal Blood Flow Response After a Histamine Skin Prick. | Inter-arm and Inter-period Reproducability of the Dermal Blood Flow Response After a Histamine Skin Prick. | NCT04396977 |
| To determine the minimum amount of Dermatophagoides pteronyssinus allergen extract producing a positive skin reaction. | Biological standardization of Dermatophagoides pteronyssinus allergen extract to determine the biological activity in histamine equivalent units (HEP). | EUCTR2012-001939-31-ES |
| The effect of histamine on sudomotor function | The effect of histamine on sudomotor function - The effect of histamine on sudomotor function | JPRN-UMIN000009247 |
| A clinical trial to study the effectiveness of Dermacyte® A clinical trial to study the effectiveness of Dermacyte® Cosmetic Cream in reducing itching, redness and swelling due to Histamine. | A Prospective, Randomized, Double-blind, Placebo-controlled Study to Determine the Efficacy of Dermacyte® Cosmetic Cream in Relieving Histamine-induced Pruritus and Wheal & Flare Reaction - Nil | CTRI/2012/01/002360 |
| A comparative study on action of Homoeopathic Medicines Dysenteric co and Histamine on blood values and stool culture of allergic rhinitis patients | A comparative study on action of Bowel Nosode Dysenteric co and Homoeopathic Medicine Histamine in intestinal flora of patients with allergic rhinitis | CTRI/2022/08/044753 |
| Study on the effectiveness of a low histamine diet and diamino oxidase enzyme supplementation in patients with histamine intolerance | Low histamine diet and diamino oxidase enzyme supplementation | ISRCTN64888465 |
| Biological standarization of pollen of Phleum pratense, Lolium perenne, Poa pratensis y Dactylis glomerata and its mixture to obtain extracts of these pollens with a potency provokes the same skin reaction in sensitive patients that the reaction the histamine produces in the subjects. | Biological standarization of allergic extracts of will grasses: Phleum pratense, Lolium perenne, Poa pratensis y Dactylis glomerata and its mixture to determinate their biological activity, the In House Reference Preparation, measures in histamine unit equivalents (HEP) in sensitized patients | EUCTR2019-002644-24-ES |
| Histamine Dihydrochloride and Interleukin-2 in Primary Resectable Pancreatic Cancer | A Phase I/II Trial of Peri- and Postoperative Treatment With Histamine Dihydrochloride and Low-dose Interleukin-2 in Patients With Primary Resectable Pancreatic Cancer | NCT05810792 |
| To determine the minimum amount of Artemisia vulgaris allergen extract producing a positive skin reaction. | Biological standardization of Artemisia vulgaris allergen extract to determine the biological activity in histamine equivalent units (HEP). | EUCTR2013-001310-15-ES |
| Effects of mometazone furoate hydrate on expression of histamine H1 receptor and allergy-related cytokines of nasal mucosa in healthy volunteers. | Effects of mometazone furoate hydrate on expression of histamine H1 receptor and allergy-related cytokines of nasal mucosa in healthy volunteers. - Effects of mometazone furoate hydrate on expression of histamine H1 receptor and allergy-related cytokines of nasal mucosa in healthy volunteers. | JPRN-UMIN000006094 |
| Bronchial Hyperreactivity During Histamine Passive Exposure | Are Technicians Showing Bronchial Hyperreactivity Able to Safely Perform Bronchial Provocation Tests? | NCT01937494 |
| Dietary Intervention for Eczema | Efficacy of Food Intervention Targeting Salicylates, Histamine and Allergens (FISHA) for Symptom Control in Adults with Moderate-to-Severe Atopic Dermatitis: A Randomised Controlled Trial | ACTRN12624001394538 |
| Histamine H1/H2 Receptors and Training Adaptations | Role of Histamine H1/H2 Receptors in the Health- and Performance-promoting Adaptations to High-intensity Interval Training | NCT04450134 |