| L-tetrahydropalmatine (l-THP) Treatment for Cocaine Use Disorder | L-tetrahydropalmatine (l-THP) Treatment for Cocaine Use Disorder | NCT02139761 |
| Homeopathic medicines as complementary treatment of cocaine dependence. | Fifty-millesimal potencies of Opium and Erythroxylum coca as complementary treatment of cocaine dependence: pilot, randomized, placebo controlled, double-blind study - COCACRACK-Study | RBR-67zvt5 |
| Homeopathy in the cocaine-crack dependence. | Homeopathic potencies of Opium and Erythroxylum coca in the integrative treatment of cocaine dependence: randomized, parallel group, placebo controlled, double-blind trial - COCACRACK Study-2 | RBR-2xzcwz |
| Homeopathy on primary care of cocaine-related disorders | Homeopathy on primary care of cocaine-related disorders - ---: --- | RBR-8mj2qf |
| Homeopathy on the integrative care of cocaine-related disorders | Homeopathy on the integrative care of cocaine-related disorders: confirmatory, randomized, placebo-controlled, double-blind, crossover clinical trial (Cocacrack-3 Study) - Cocacrack-3 Study | JPRN-UMIN000040161 |
| Use of intranasal oxytocin during detoxification of crack/cocaine | Protection targets to women crack users | RBR-7djc66 |
| Pharmacokinetic and Safety Evaluation of L-tetrahydropalmatine (l-THP) With Cocaine Exposure in People With a History of Cocaine Use | Pharmacokinetic and Safety Evaluation of L-tetrahydropalmatine (l-THP) With Cocaine Exposure in People With a History of Cocaine Use | NCT01631383 |
| Rivastigmine and Huperzine A as Treatments for Cocaine Dependence | Rivastigmine and Huperzine A as Treatments for Cocaine Dependence | NCT01030692 |
| Effect of cannabidiol in the treatment of crack dependence | Study of the feasibility, safety and short-term results of the therapeutic use of cannabidiol (CBD) in the treatment of cocaine dependence in the form of crack | RBR-4stgs8 |
| Progesterone and Atomoxetine for Cocaine Cessation | Progesterone and Atomoxetine for Cocaine Cessation | NCT01741376 |
| Progesterone for Postpartum Cocaine Relapse | Progesterone for Postpartum Cocaine Relapse | NCT01249274 |
| Progesterone Treatment for Cocaine-dependent Women: A Pilot Study | Progesterone Treatment for Cocaine-dependent Women: A Pilot Study | NCT00632099 |
| Progesterone for the Treatment of Cocaine Dependence - 1 | Interactions Between Progesterone and Cocaine in Women | NCT00218257 |
| Caffeine and Cocaine | Experiment 1: Adenosine Receptor A2A Antagonists and Cocaine Dependence | NCT00733993 |
| The Effect of Yohimbine on Cocaine Cue Reactivity | SCOR on Sex and Gender Factors Affecting Women's Health | NCT00535002 |
| Efficacy of Caffeine, With and Without Biperiden, in the Detoxification of Cocaine Dependent Patients | Efficacy of Caffeine, With and Without Biperiden, in the Detoxification of Cocaine Dependent Patients | NCT00495092 |
| Efficacy of Caffeine, With and Without Biperiden, as a Maintenance Treatment for Cocaine Dependence | Efficacy of Caffeine, With and Without Biperiden, as a Maintenance Treatment for Cocaine Dependence | NCT00495183 |
| Reserpine for the Treatment of Cocaine Dependence - 1 | Phase 2, Double-Blind, Placebo-Controlled Trial of Reserpine for the Treatment of Cocaine Dependence | NCT00033033 |
| Cocaine Withdrawal and Pharmacotherapy Response | Cocaine Withdrawal and Pharmacotherapy Response | NCT00566969 |
| Topical Application of Cocaine HCl 4% and 10% on Safety and Efficacy in Local (Topical) Anesthesia | A Phase III Investigation of Topical Application of Cocaine HCl 4% and 10% on Safety and Efficacy in Local (Topical) Anesthesia for Diagnostic Procedures and Surgeries on or Through Accessible Mucous Membranes of the Nasal Cavities. | NCT01746940 |
| Efficacy of Varenicline in Methadone-Stabilized Cocaine Users | Efficacy of Varenicline in Methadone-Stabilized Cocaine Users | NCT00567320 |
| Study of Safety and Potential Efficacy of SYN117 in Cocaine Dependent Volunteers | A Human Laboratory Assessment of the Safety and Potential Efficacy of SYN117 (Nepicastat) in Cocaine-dependent Volunteers Receiving Cocaine | NCT00656357 |
| Comparison of anesthetic efficacy between 10% lidocaine hydrochloride with adrenaline (1:100000) and 4% cocaine hydrochloride in nasal endoscopic examination | Comparison of anesthetic efficacy between 10% lidocaine hydrochloride with adrenaline (1:100000) and 4% cocaine hydrochloride in nasal endoscopic examination | TCTR20210807003 |
| Retraining of automatic action tendencies and working memory training in individuals with cocaine dependency | Retraining of automatic action tendencies and working memory training in individuals with cocaine dependency - AT and WM training in cocaine dependent patients | NL-OMON32258 |
| Perioperative decongestion and hemostasis, and postoperative analgesia for FESS after intranasal application of cocaine, tetracaine-oxymetazoline or ropivacaine-oxymetazoline | Perioperative decongestion and hemostasis, and postoperative analgesia for FESS after intranasal application of cocaine, tetracaine-oxymetazoline or ropivacaine-oxymetazoline - Decongestion for FESS after application of intranasal medication | NL-OMON32081 |
| Carbidopa/Levodopa Combined With Behavioral Therapy for the Treatment of Cocaine Dependence | Contingency Management Plus Levodopa/Carbidopa for Treatment of Cocaine Dependence | NCT00713583 |
| Why methylphenidate is not successful in cocaine-dependent ADHD patients: a SPECT study comparing DAT before and after methylphenidate treatment in ADHD patients with and without cocaine dependence | Why methylphenidate is not successful in cocaine-dependent ADHD patients: a SPECT study comparing DAT before and after methylphenidate treatment in ADHD patients with and without cocaine dependence | EUCTR2009-012261-61-NL |
| Comparison of xylometazoline vs. cocaine for prevention of nose bleeds upon intubation | Comparison of the effect of xylometazoline and cocaine on epistaxis when administered as local vasoconstrictors prior to nasal intubation | EUCTR2021-000691-11-DK |
| Modeling Impaired Judgement in Cocaine Abusers - 6 | Modeling Impaired Judgement in Cocaine Abusers | NCT00015236 |
| Prepulse Inhibition of Startle in Cocaine Dependence - 7 | Prepulse Inhibition of Startle in Cocaine Dependence (Human) | NCT00015249 |
| Rapid Evaluation of Amantadine for Treatment of Cocaine Abuse/Dependence - 4 | Rapid Evaluation of Cocaine Pharmacotherapies (Amantadine) | NCT00000301 |
| Neurobehavioral Mechanisms of Cocaine Choice | Neurobehavioral Mechanisms of Cocaine Choice | NCT04296006 |
| Sociodemographic profile and natural history of crack use among users of different Brazilian states | Twenty-five years of crack cocaine use in Brazil: changes on user’s profile who are seeking help This study, involving multiple Brazilian regions, aimed to compare the profile of crack cocaine users seeking treatment sixteen years apart. | ISRCTN33967634 |
| Stress and social cognition in cocaine users | The effect of psychosocial and craving-induced stress on social cognition and decision-making in cocaine users: a longitudinal approach | ISRCTN10690316 |
| Behavioral Effects of Drugs (Inpatient): 38 | Influence of Craving Manipulation on Cocaine Self-Administration | NCT03954938 |
| Suvorexant and Cocaine | Influence of Orexin Antagonism on Motivation for Cocaine | NCT03937986 |
| Behavioral Effects of Drugs: Inpatient (35) | Influence of Methylphenidate and Duloxetine Maintenance on Pharmacodynamic Effects of Cocaine | NCT03519022 |
| Therapeutic Cocaine Vaccine: Human Laboratory Study | Tests of a Therapeutic Cocaine Vaccine | NCT00965263 |
| Cognitive Enhancement as a Target for Cocaine Pharmacotherapy | Cognitive Enhancement as a Target for Cocaine Pharmacotherapy | NCT01531153 |
| Investigation of Cocaine Addiction Using mGluR5 PET and fMRI | Investigation of Cocaine Addiction Using mGluR5 PET and fMRI | NCT03471182 |
| The influence of cocaine and cannabis on impulsivity. | Cognitive and motor impulsivity in regular cannabis and cocaine users as a function of COMT and DBH genotype. | NL-OMON25495 |
| Human Dopamine Transported Imaging in Cocaine Abuse: 2 - 2 | Human Dopamine Transported Imaging in Cocaine Abuse: 2 | NCT00000316 |
| Study of the cardiac safety of Ibogaine accompanied by psychotherapy in the treatment of addiction to cocaine and crack. | Cocaine and crack Addiction Treatment with Ibogaine - CATI: Cocaine Addiction Treatment Ibogaine | RBR-9zpc27 |
| Treatment With Lorcaserin for Cocaine Use: The TLC Study | Treatment With Lorcaserin for Cocaine Use: The TLC Study | NCT03192995 |
| The Role of Neuroactive Steroids in Stress, Drug Craving and Drug Use in Cocaine Use Disorders | The Role of Neuroactive Steroids in Stress, Drug Craving and Drug Use in Cocaine Use Disorders | NCT03953612 |
| Exploration of implicit biases in adults who are current cocaine users | Web-based cognitive bias modification in South African cocaine users | NL-OMON22059 |
| Cocaine and Zolmitriptan | Behavioral Effects of Drugs (Inpatient): 42 (Cocaine and Zolmitriptan) | NCT05019430 |
| Biperiden effect to reduce the desire to use cocaine/crack | Effects of biperiden (muscarinic antagonist) on cocaine/crack dependence | RBR-8dzrvjg |
| Imaging the Neurobiology of Behavioral and Medication Treatment for Cocaine Dependence | Imaging the Neurobiology of Behavioral and Medication Treatment for Cocaine Dependence | NCT01468012 |
| Acute Withdrawal From Smoked Cocaine - 9 | Acute Withdrawal From Smoked Cocaine | NCT00000292 |
| Stress Hormones and Human Cocaine Use - 7 | Stress Hormones and Human Cocaine Use | NCT00000290 |
| Cognitive Remediation for Cocaine Dependence | Cognitive-enhancing DA Medications for Cocaine Dependence | NCT01393457 |
| Brain Imaging: Cocaine Effects & Medication Development - 5 | Brain Imaging: Cocaine Effects & Medication Development | NCT00000270 |
| Pathophysiological Subtyping of Abnormalities in Cocaine Dependence - 9 | Pathophysiological Subtyping of Abnormalities in Cocaine Dependence | NCT00015275 |
| Pharmacogenetics of Disulfiram for Cocaine | Effectiveness of Disulfiram for Treating Cocaine Dependence in Individuals With Different Dopamine Beta Hydroxylase (DBH) Genes | NCT00149630 |
| Development of Human Laboratory Study Model of Cocaine Relapse Prevention. - 1 | Development of Human Laboratory Study Model of Cocaine Relapse Prevention | NCT00040066 |
| Assessment of Potential Interactions Between Cocaine and RPR 102681 - 1 | Potential Interactions Between IV Cocaine and RPR 102681 | NCT00067535 |
| Striatal Effective Connectivity to Predict Treatment Response in Cocaine Misuse | Striatal Effective Connectivity to Predict Treatment Response in Cocaine Misuse | NCT02080819 |
| Alternative medications for the treatment of dually dependent on opiates and cocaine: a single-center placebo-controlled trial | Alternative medications for the treatment of dually dependent on opiates and cocaine: a single-center placebo-controlled trial | TCTR20170201001 |
| Development of Human Laboratory Study Model of Cocaine Relapse Prevention II - 1 | Cocaine Relapse Prevention II | NCT00094315 |
| Study to Improve Scientific Understanding of the Cardiovascular Actions of Cocaine | Cocaine and Sympathetic Nerve Activity in Humans | NCT00338546 |
| Effects of Aripiprazole on Cocaine Craving and Self-Administration | Effects of Aripiprazole on Cocaine Craving and Self-Administration | NCT00373880 |
| Effects of Vigabatrin on Cocaine Self-Administration | Effects of Vigabatrin on Cocaine Self-Administration | NCT00373581 |
| Metabolic Effects of Cocaine | Elucidating the Role of the Hypothalamic-Pituitary-Adrenal (HPA) Axis in the Mechanisms Underlying Cocaine Dependence | NCT00451230 |
| A two-phase study investigating the quality of life benefit of additional 0.5% cocaine mouthwash to institutional standard of care mucositis management in head and neck cancer patients undergoing radiotherapy or chemoradiotherapy. | A two-phase study investigating the quality of life benefit of additional 0.5% cocaine mouthwash to institutional standard of care mucositis management in head and neck cancer patients undergoing radiotherapy or chemoradiotherapy. | ACTRN12625000158460 |
| Flourishing program for crack/cocaine addicts | Implementation of an intervention based on positive psychology: program flourishing as a complementary therapy in the treatment of inpatients addicted to chemical dependency | RBR-7437tk4 |
| Innovative Cognitive and Behavioral Psychotherapy for Cocaine Use Disorder | Virtual Reality Cue Exposure Therapy for Cocaine Craving: an Innovative Cognitive and Behavioral Psychotherapy for Cocaine Use Disorder (Psychothérapie Innovante COmportementale et Cognitive Pour le Trouble d'Usage de Cocaïne; PICOC) | NCT05833529 |
| Nasal decongestant study: a prospective double-blind randomised comparative study of nasal decongestant and vasoconstrictive efficacy of two commonly used preparations, namely cocaine and adrenaline, with normal saline and adrenaline with normal saline | | ISRCTN24006995 |
| Intranasal Cocaine and Temperature Regulation During Exercise | Intranasal Cocaine and Temperature Regulation During Exercise | NCT05809453 |
| Virtual Reality Exposure and Respiratory Relaxation-Based Coping With Cocaine Craving in Cocaine Users | Development and Evaluation of a Virtual Reality Application for Eliciting Craving and Its Physiological Arousal in Cocaine Users | NCT05557149 |
| Drug test detection 24 hours after giving cocaine through the nose to contract the blod vessels in it | Drug test detection 24 hours after nasal administration of cocaine as a local vasoconstrictor prior to nasal intubation | EUCTR2021-000709-26-DK |
| Effectiveness of Amantadine and Propranolol for Treating Cocaine Dependence - 2 | A Double-Blind, Placebo Controlled Trial of Propranolol and Amantadine for the Treatment of Cocaine Dependent Subjects With Severe Cocaine Withdrawal Symptoms | NCT00158132 |
| Does cocaine routinely used in sinus surgery get absorbed into the body and have an effect on your sleep during anaesthetic? | The systemic absorption of cocaine and the effect on depth of anaesthesia using intranasal atomised modified Moffat’s solution prior to endoscopic sinus surgery (ESS) | ACTRN12617000303347 |
| Efficacy of N-acetylcysteine on the Craving Symptoms of Abstinent Hospitalized Patients with Cocaine Addiction | Efficacy of N-acetylcysteine on the Craving Symptoms of Abstinent Hospitalized Patients with Cocaine Addiction | NCT03423667 |
| Effect of N-acetylcysteine on Alcohol and Cocaine Use Disorders: A Double-Blind Randomized Controlled Trial. | The Effect of N-acetylcysteine (NAC) on Treatment of Alcohol and Cocaine Use Disorders: A Double-Blind Randomized Controlled Trial. | NCT03018236 |
| Topiramate-Phentermine Combinations for Cocaine Dependence | Topiramate-Phentermine Combinations for Cocaine Dependence | NCT02239913 |
| Phendimetrazine and Cocaine | Safety and Tolerability of Cocaine During Phendimetrazine Maintenance | NCT02233647 |
| Galantamine Effects on Cognitive Function in Abstinent Cocaine Users | Galantamine Effects on Cognitive Function in Abstinent Cocaine Users | NCT00606801 |
| n-Acetylcysteine and Cocaine | Motivation for Cocaine and Non-Drug Reinforcers: Targeting Glutamate Homeostasis | NCT02141620 |
| Validation of a Remote Wireless Sensor Network (WSN) Approach to the Individualized Detection of Cocaine Use in Humans | | NCT02018263 |
| Establishing and Eliminating Cue-drug Associations in Human Cocaine Addiction | Establishing and Eliminating Cue-drug Associations in Human Cocaine Addiction | NCT01978457 |
| Dexmedetomidine for Reversal of Cocaine's Effects on the Heart | Study of Dexmedetomidine for the Reversal of Cocaine's Effects on Myocardial Perfusion | NCT01927640 |
| A Novel Therapy for cocaine dependence during abstinence: A randomized clinical trial | A Novel Therapy for cocaine dependence during abstinence: A randomized clinical trial | TCTR20170112001 |
| More creative on cocaine? | More creative on cocaine? | EUCTR2013-000179-34-NL |
| Cocaine en creativiteit | ‘More creative on cocaine?’ | NL-OMON21211 |
| Effect of Zonisamide on Cocaine Reinforcement, Craving, and Relapse | Effect of Zonisamide on Cocaine Reinforcement, Craving, and Relapse | NCT01137890 |
| Interactions Between Intravenous Cocaine and Acetazolamide or Quinine | Pharmacodynamic and Pharmacokinetic Interactions Between Intravenous Cocaine and Acetazolamide or Quinine | NCT01851473 |
| Snow Control | Snow Control: a web-based self-help tool to reduce dependence in problematic cocaine users ? a randomized controlled trial | ISRCTN93702927 |
| A Randomized, 4-sequence, 2-period, Double-blind, Placebo Controlled Study With a DSM-IV-TR Diagnosis of Cocaine Abuse | A Randomized, Double-blind, Placebo-controlled, Dose of RBP-8000 Following IV Cocaine to Evaluate the Pharmacokinetics Parameters of RBP-8000 and Cocaine and to Assess the Effects of Drug on Cocaine-induced Physiologic and Behavioral Effects in Cocaine Abusing Subjects | NCT01846481 |
| Modafinil, DRD4 Genotype and Cocaine Relapse | Modafinil and DRD4 Genotype in a Human Laboratory Model of Cocaine Relapse | NCT01778010 |
| Vitamin D and Cocaine Administration | Testing Restoring Effects of Vitamin D on the Dopamine System: A Human Laboratory Study Among Cocaine Users. | NCT04826133 |
| Comparison of Topical Vasoconstriction in Endoscopic Sinus Surgery | Comparison of Topical Vasoconstriction in Endoscopic Sinus Surgery: Cocaine Versus Adrenaline | NCT01706952 |
| Improving Learning-based Treatment of Cocaine Dependence With Medication | Improving Learning-based Treatment of Cocaine Dependence With Medication | NCT01526538 |
| Pharmacotherapy & CM for Opioid and Cocaine Dependence | Pharmacotherapy & CM for Opioid and Cocaine Dependence | NCT00838981 |
| GLP-1 Agonism for Blocking Cocaine Euphoria and Self-Administration | GLP-1 Agonism for Blocking Cocaine Euphoria and Self-Administration | NCT02302976 |
| Snow Control 2.0 - web-based interventions for the reduction of cocaine use | Snow Control 2.0 - the effects of chat-counseling and web-based self-help, web-based self-help alone and a waiting list control program on cocaine use in problematic cocaine users: a randomized controlled trial | ISRCTN12205466 |
| Impact of a Non-Drug Choice on Cocaine Reinforcement | Impact of a Non-Drug Choice on Cocaine Reinforcement | NCT01906346 |
| Human Dopamine Transported Imaging in Cocaine Abuse: 1 - 1 | Human Dopamine Transported Imaging in Cocaine Abuse: 1 | NCT00000315 |
| Impact of Sustained Release d-Amphetamine on Choice Between Cocaine and a Non-Drug Reinforcer | Impact of Sustained Release d-Amphetamine on Choice Between Cocaine and a Non-Drug Reinforcer | NCT02383043 |
| Pilot Feasibility Study of Cognitive Control in Cocaine Dependence | Pilot Feasibility Study of Cognitive control in cocaine dependence: A multi-centre randomized controlled trial to pilot targeting craving for cocaine using memory reconsolidation techniques | ISRCTN16462783 |
| Cocaine Use and Outcomes of General Anesthesia | Cocaine Use and General Anesthesia: A Prospective Study of Cardiovascular and Anesthetic Effects | NCT02692534 |
| Drug Interaction and Self Administration Studies of Compounds for Cocaine Use Disorder | Phase I Drug Interaction and Self Administration Studies of Compounds for Cocaine Use Disorder | NCT02537873 |
| Complementary Combination Therapy for Cocaine Dependence | Complementary Combination Therapy for Cocaine Dependence | NCT02538744 |
| Reinforcing Effects of Cocaine During Phendimetrazine Maintenance | Behavioral Effects of Drugs (Inpatient): 31 (Cocaine and Phendimetrazine) | NCT02522325 |
| Medications for Stopping Cocaine Dependence and Preventing Relapse | Screening Medications for Cocaine Cessation and Relapse Prevention | NCT00218023 |
| Behavioral Therapy Combined With Carbidopa/Levodopa for the Treatment of Cocaine Dependence | Behavioral Strategies to Maximize the Efficacy of Pharmacotherapy for Cocaine Dependence: Relapse Prevention With Contingency Management Procedures | NCT00218075 |
| Clavulanic Acid (CLAV) and Cocaine Interaction Safety Study | Phase 1, Double-Blind, Placebo-Controlled Assessment of Potential Interactions Between Intravenous Cocaine and Clavulanic Acid | NCT02563769 |
| A Study of Metyrapone and Oxazepam Combination Product (EMB-001) and Cocaine | A Phase 1b, Randomized, Double-Blinded, Multiple-Dose, Placebo Controlled, Crossover Study To Evaluate The Safety, Tolerability And Pharmacokinetic Effects Of A Metyrapone And Oxazepam Combination (EMB-001) When Co-Administered With Cocaine | NCT02856854 |
| Topical Application of Cocaine HCl 4%, or 10%, or Placebo Solution in Local (Topical) Anesthesia | Phase III Topical Application of Cocaine HCl 4% Solution on Safety/Efficacy & Cocaine HCl 4% & 10% Solution on Safety in Local Anesthesia for Diagnostic Procedures & Surgeries on or Through Accessible Mucous Membranes of the Nasal Cavities | NCT02500836 |
| Cannabidiol and Cocaine Craving/Dependence | Cannabidiol as a New Treatment for Cocaine Addiction | NCT02559167 |
| Effectiveness of GABA Agonists in Reducing the Reinforcing Effects of Cocaine | GABA Agonists as Pharmacotherapies for Cocaine Abuse | NCT00218166 |
| Use of Intranasal Oxytocin during Detoxification of Crack/Cocaine | Protection targets to women crack users | RBR-383vcp |
| Galantamine to Enhance Cognitive Behavioral Therapy for Cocaine Abuse | Galantamine to Enhance Cognitive Behavioral Therapy for Cocaine Abuse With Methadone Maintained Individuals | NCT00809835 |
| Study to Assess Potential Interactions Between Intravenous Cocaine and Oral Lorcaserin | Phase 1, Double-Blind, Placebo-Controlled, Parallel-Group Study to Assess Potential Interactions Between Intravenous Cocaine and Oral Lorcaserin | NCT02393599 |
