IMPPAT Phytochemical information: 
Amantadine

Amantadine
Clinical trials
Public title (as per ICTRP)Scientific title (as per ICTRP)Trial identifier
Randomized crossover trial comparing memantine or amantadine for Parkinson's disease with motor fluctuations in JuntendoRandomized crossover trial comparing memantine or amantadine for Parkinson's disease with motor fluctuations in Juntendo - MAP-JJPRN-UMIN000010596
The effect of amantadine and Q10 in fatigue of the Multiple Sclerosis patientsComparison of the effect of amantadine and coenzymeQ10 on the fatigue of the Multiple Sclerosis patientsIRCT2013092814792N1
Amantadine + rTMS as a Neurotherapeutic for Disordered ConsciousnessAmantadine + rTMS as a Neurotherapeutic for Disordered ConsciousnessNCT02025439
ADS-5102 for the Treatment of Levodopa Induced Dyskinesia (EASE LID Study)Efficacy and Safety of ADS-5102 (Amantadine HCl) Extended Release Capsules for the Treatment of Levodopa Induced Dyskinesia in Parkinson's Disease Patients (EASE LID Study)NCT02136914
Efficacy and Safety of Amantadine Hydrogen Chloride (HCl) ER Tablets in Parkinson's Disease Subjects With LIDA Multicenter, Randomized, Placebo-controlled, Double-blind, 26 Week Study to Evaluate the Efficacy and Safety of Amantadine HCl Extended Release Tablets in Parkinson's Disease Subjects With Levodopa-Induced DyskinesiasNCT02153632
Amantadine to Speed Awakening After Cardiac ArrestAmantadine to Speed Awakening After Cardiac ArrestNCT02486211
Amantadine for Improving Neurologic Symptoms in Ataxia-TelangiectasiaThe Effect of Amantadine on Movement Disorder in Ataxia-TelangiectasiaNCT00950196
Open-Label Safety Study of ADS-5102 in PD Patients With LIDOpen-Label Safety Study of ADS-5102 (Amantadine HCl) Extended Release Capsules for the Treatment of Levodopa Induced Dyskinesia (LID)NCT02202551
A 26 Week Clinical Study to Evaluate the Use of Long-Acting Amantadine to Treat Parkinson's Disease Patients with Abnormal Involuntary Movements caused by LevodopaA Multicenter, Randomized, Placebo-controlled, Double-blind, 26 Week Study to Evaluate the Efficacy and Safety of Amantadine HCl Extended Release Tablets in Parkinson's Disease Subjects with Levodopa-Induced DyskinesiasEUCTR2014-001132-10-ES
A 16 Week Clinical Study to Evaluate the Use of Long-Acting Amantadine to Treat Parkinson's Disease Patients with Abnormal Involuntary Movements caused by LevodopaA Multicenter, Randomized, Placebo-controlled, Double-blind, 16 Week Study to Evaluate the Efficacy and Safety of Amantadine HCl Extended Release Tablets in Parkinson's Disease Subjects with Levodopa-Induced DyskinesiasEUCTR2014-001131-36-ES
Efficacy of amantadine in acquired brain injury.Efficacy of amantadine on behavioural and emotional problems and impairment of executive functioning due to acquired brain injury to the frontal lobes: a series of single case experimental design studies.EUCTR2012-005723-33-NL
Comparing the efficacy of bupropion and amantadine on sexual dysfunction induced by a selective serotonin reuptake inhibitorComparing the efficacy of bupropion and amantadine on sexual dysfunction induced by a selective serotonin reuptake inhibitorIRCT201409275280N17
Effect of Amantadine Administration on Spatial Functioning Following Traumatic Brain InjuryEffect of Amantadine Administration on Spatial Functioning Following Traumatic Brain InjuryNCT02321761
A Randomized Open Label Study Comparing the Safety, Tolerability and Pharmacokinetics (PK) of Amantadine Hydrochloride and Ribavirin with Oseltamivir Phosphate (TCAD) Administered Orally Versus Oseltamivir alone Administered Orally to Influenza A Virus Infected Hospitalized Immunocompromised PatientsA Randomized Open Label Study Comparing the Safety, Tolerability and Pharmacokinetics (PK) of Amantadine Hydrochloride and Ribavirin with Oseltamivir Phosphate (TCAD) Administered Orally Versus Oseltamivir alone Administered Orally to Influenza A Virus Infected Hospitalized Immunocompromised Patients - TOMI trial: Triple Or Monotherapy in InfluenzaNL-OMON32938
An investigation of the clinical efficacy of amantadine on depressive syptoms and cognitive deficits in Borna Disease Virus (BDV) infected patients with an affective psychosis; a prospective, randomized, double-blind, placebo controlled, monocentric study.An investigation of the clinical efficacy of amantadine on depressive syptoms and cognitive deficits in Borna Disease Virus (BDV) infected patients with an affective psychosis; a prospective, randomized, double-blind, placebo controlled, monocentric study.DRKS00007649
Efficacy and Safety of Amantadine Hydrochloride (HCl) ER Tablets to Treat Parkinson's Disease Patients With LID.A Multicenter, Randomized, Placebo-controlled, Double-blind, 16 Week Study to Evaluate the Efficacy and Safety of Amantadine HCl Extended Release Tablets in Parkinson's Disease Subjects With Levodopa-Induced DyskinesiasNCT02153645
post operative pain controlPreoperative single dose of oral Amantadine for acute and chronic post operative pain control in Mandibular fractureIRCT201406201772N13
The effects of a combination therapy of clonidine with dextromethorphan and/or amantadine on opium withdrawal syndrome compared with the single therapy of clonidineStudy of the effects of a combination therapy of clonidine with dextromethorphan and/or amantadine on opium withdrawal syndrome compared with the single therapy of clonidineIRCT201207196972N2
Clinical trial of Amantadine HCl for hypoxic encephalopathyClinical trial of Amantadine HCl for hypoxic encephalopathy - Amantadine HCl for hypoxic encephalopathyJPRN-UMIN000003160
Amantadine as Adjunctive Therapy to Antipsychotics in SchizophreniaA Double-blind, Randomized, Placebo-controlled Trial With Amantadine as Adjunctive Therapy to Antipsychotics in SchizophreniaNCT00999505
Amantadine Versus Ritalin in the Treatment of Attention Deficit Hyperactivity Disorder (ADHD)Amantadine VS Ritalin in the Treatment of ADHD: a Double Blind Randomized TrialNCT01099059
A Randomized Open Label Study Comparing the Efficacy, Safety, and Tolerability of Oral Administration of Amantadine and Ribavirin with Oseltamivir Versus Oseltamivir to Influenza A Virus Infected Immunocompromised Subjects - TCAD Therapy for treatment of influenza A in immunocompromised subjectsA Randomized Open Label Study Comparing the Efficacy, Safety, and Tolerability of Oral Administration of Amantadine and Ribavirin with Oseltamivir Versus Oseltamivir to Influenza A Virus Infected Immunocompromised Subjects - TCAD Therapy for treatment of influenza A in immunocompromised subjectsEUCTR2009-015850-39-NL
Study of Amantadine for Risperidone Consta or Paliperidone Treated Patients to Decrease Prolactin ElevationAmantadine Addition to Paliperidone ER or Risperidone Consta Therapy for Prolactin ElevationNCT00975611
Pilot Study of Maintenance Therapy With Intravenous AMANTADINEMaintenance Therapy of Intravenous Amantadine in Patients With Idiopathic Parkinson Disease Who Are Not Optimally Treated With Anti Parkinson MedicationsNCT01190553
Comparing the Efficacy, Safety, and Tolerability of Combination Antivirals (Amantadine, Ribavirin, Oseltamivir) Versus Oseltamivir for the Treatment of Influenza in Adults at Risk for ComplicationsA Randomized Double-Blind Phase 2 Study Comparing the Efficacy, Safety, and Tolerability of Combination Antivirals (Amantadine, Ribavirin, Oseltamivir) Versus Oseltamivir for the Treatment of Influenza in Adults at Risk for ComplicationsNCT01227967
The Effect of IV Amantadine on Freezing of Gait (FOG) Resistant to Dopaminergic TherapyA Double Blind, Placebo-controlled Study for the Effect of IV Amantadine on Freezing of Gait (FOG) Resistant to Dopaminergic TherapyNCT01313819
Effect of Intravenous Amantadine on Gait Freezing in Parkinson's DiseaseRandomized Double-blind Placebo-controlled Trial of Intravenous Amantadine on Gait Freezing in Patients With Parkinson's DiseaseNCT01313845
Influence of high dose intraoperative remifentanil with or without amantadine on postoperative pain intensity and morphine consumption in major abdominal surgery patientsInfluence of high dose intraoperative remifentanil with or without amantadine on postoperative pain intensity and morphine consumption in major abdominal surgery patientsDRKS00004626
Amantadine in the treatment of autismA double - blind placebo controlled traial of Amantadine added to risperidone in patint with autistic disorderIRCT201106101556N25
Oral Triple Combination Antiviral Drug Therapy for Treatment of Influenza A in Immunocompromised SubjectsA Randomized Open Label Study Comparing the Efficacy, Safety and Tolerability of Oral Administration of Amantadine and Ribavirin and Oseltamivir Versus Oseltamivir to Influenza A Virus Infected Immunocompromised Subjects.ACTRN12609000708257
A Phase IIa, Double-Blind, Placebo-Controlled, Randomised, Fourfold Cross-Over Study to Investigate the Glucose Lowering Effects of Dextromethorphan and Amantadine in Subjects with Type 2 Diabetes Mellitus (T2DM) after an Oral Glucose Tolerance TestA Phase IIa, Double-Blind, Placebo-Controlled, Randomised, Fourfold Cross-Over Study to Investigate the Glucose Lowering Effects of Dextromethorphan and Amantadine in Subjects with Type 2 Diabetes Mellitus (T2DM) after an Oral Glucose Tolerance TestEUCTR2011-002986-39-DE
Efficacy Study of Amantadine to Treat Gait Dysfunction and Freezing in Parkinson's DiseaseEfficacy of Amantadine for Gait Dysfunction and Gait Freezing in Patients With Parkinson's DiseaseNCT01652534
Effectiveness of Amantadine Hydrochloride for Treatment of Severe Traumatic Brain Injury (TBI)A Multicenter Prospective Randomized Controlled Trial of the Effectiveness of Amantadine Hydrochloride in Promoting Recovery of Function Following Severe Traumatic Brain InjuryNCT00970944
Dextromethorphan, Amantadine and Glucose Homeostasis in Diabetes SubjectsA Phase IIa, Double-blind, Placebo-controlled, Randomised, Fourfold Crossover Study to Investigate the Glucose Lowering Effects of Dextromethorphan and Amantadine in Subjects With Type 2 Diabetes Mellitus (T2DM) After an Oral Glucose Tolerance TestNCT01441986
Effect of co-administration of Amantadine and Aspirin on fatigue in patients with multiple sclerosisTherapeutic effect of co-administration of Amantadine and Aspirin on fatigue in patients with multiple sclerosis: a randomized placebo-controlled double-blind studyIRCT201112208430N3
Amantadine and L-DOPA-induced Dyskinesia in Early Parkinson's DiseaseImpact of Amantadine on L-DOPA-induced Dyskinesia in Early Parkinson's Disease: a Placebo-controlled Randomized Study (the PREMANDYSK Study)NCT01538329
STUDY OF EFFECTIVENESS, TOLERABILITY AND SAFETY OF THERAPY WITH AMANTADINE IN DEGENERATIVE ATAXIASRANDOMIZED, DOUBLE-BLIND, PLACEBO CONTROLLED, STUDY OF EFFECTIVENESS, TOLERABILITY AND SAFETY OF THERAPY WITH AMANTADINE IN DEGENERATIVE ATAXIASEUCTR2012-003315-63-ES
Extended Release Amantadine Safety and Efficacy Study in Levodopa-Induced Dyskinesia (EASED Study)Extended Release Amantadine Safety and Efficacy Study in Levodopa-Induced Dyskinesia (EASED Study)NCT01397422
Efficacy and Safety of Combination Therapies With Oseltamivir & Zanamivir or Oseltamivir & Amantadine Versus Oseltamivir Monotherapy in the Treatment of Seasonal Influenza A InfectionEfficacy and Safety of Combination Therapies With Oseltamivir & Zanamivir or Oseltamivir & Amantadine Versus Oseltamivir Monotherapy in the Treatment of Seasonal Influenza A InfectionNCT00830323
Topiramate as an Adjunct to Amantadine in the Treatment of Dyskinesia in Parkinson's DiseaseTopiramate as an Adjunct to Amantadine in the Treatment of Dyskinesia in Parkinson's DiseaseNCT01789047
Effect of amantadine on methamphetamine-withdrawal induced fatigueEffect of amantadine on controlling methamphetamine-withdrawal induced fatigue (double-blind, controlled clinical trial)IRCT2015111524853N2
Amantadine and Functional Improvement Following ABI Measured by MRI Tractography; A Pilot StudyMechanism of Amantadine and Functional Improvement Following Acquired Brain Injury as Measured by MRI Tractography; A Pilot StudyNCT02566720
The Effect of Amantadine As Add-on Therapy for Motor Fluctuations in Advanced Parkinson's Disease: a Randomized Double-blinded Placebo-controlled TrialThe Effect of Amantadine As Add-on Therapy for Motor Fluctuations in Advanced Parkinson's Disease: a Randomized Double-blinded Placebo-controlled TrialNCT06817200
The Clinical Efficacy of Amantadine on Vegetative State Post-Traumatic Brain InjuryThe Clinical Efficacy of Amantadine on Vegetative State Post-Traumatic Brain InjuryChiCTR2400091956
AMANTADINE AND TRANSCRANIAL MAGNETIC TRANSCRANIAL MAGNETIC STIMULATION FOR FATIGUE IN MULTIPLE SCLEROSIS: A PHASE III, CONTROLLED, RANDOMISED, DOUBLE-BLIND, CROSSOVER TRIALAMANTADINE AND TRANSCRANIAL MAGNETIC TRANSCRANIAL MAGNETIC STIMULATION FOR FATIGUE IN MULTIPLE SCLEROSIS: A PHASE III, CONTROLLED, RANDOMISED, DOUBLE-BLIND, CROSSOVER TRIAL - FETEMCTIS2024-516732-97-00
Effect of Intravenous Amantadine Sulphate on Disorders of ConsciousnessEffects of Intravenous Amantadine Sulphate on Brain Dynamics and Neurobehavioral Status in Patients With Disorders of ConsciousnessNCT06443827
Study to Assess the Safety of Amantadine Hydrochloride (HCl) Intravenous (IV) Solution (MR-301) in Patients With Severe Traumatic Brain Injury (TBI).Multicenter, Double-blind, Randomized, Placebo Controlled, Study to Assess the Safety of Amantadine Hydrochloride (HCl) Intravenous (IV) Solution (MR-301), in Patients With Severe Traumatic Brain Injury (TBI).NCT06253923
A Study of Amantadine for Cognitive Dysfunction in Patients With Long-CovidFeasibility Study of Amantadine for Cognitive Dysfunction in Patients With Long-Covid: A Pilot Randomized Control TrialNCT06234462
Amantadine in cancer fatigueEvaluation of Amantadine efficacy compared to placebo in the treatment of cancer-related fatigue: a randomized, double-blind clinical trial.IRCT20181208041882N10
Amantadine Therapy for Cognitive Impairment in Long COVIDAmantadine Therapy for Cognitive Impairment Related to Post-COVID ConditionNCT06055244
Combined Cerebrolysin and Amantadine Sulfate Administration for Patients With Traumatic Brain Injury in the ICUThe Impact and Outcomes of Combined Cerebrolysin and Amantadine Sulfate Administration on Management of Patients With Traumatic Brain Injury in the ICUNCT06052787
The effect of amantadine on the recovery of patients with traumatic brain injuryThe effect of amantadine on the recovery of patients with severe brain injury: a randomized controlled clinical trialIRCT20190618043934N18
Palliative pharmacotherapy for cancer-related fatigueEfficacy of palliative pharmacotherapy with Methylphenidate, Bupropion, Ginseng, and Amantadine to improve fatigue in people with advanced cancer (5-EPIFAT)IRCT20150302021307N6
Safety and Efficacy of Amantadine Tablets for the Treatment of Parkinsons Disease (A disorder of the central nervous system that affects movement, often including tremors) and Drug-induced Extrapyramidal Reactions (involuntary or uncontrollable movements, tremors, muscle contractions) in PatientsA Prospective, Multi-centre, Single-arm, Phase IV Study to Assess the Safety and Efficacy of Amantadine Extended Release Tablets for the Treatment of Parkinsons Disease and Drug-induced Extrapyramidal Reactions in Adult PatientsCTRI/2023/04/051973
Amantadine and Transcranial Magnetic Stimulation for Treating Fatigue in Multiple SclerosisAmantadine and Transcranial Magnetic Stimulation for Treating Fatigue in Multiple Sclerosis: Phase III Study, Controlled, Randomized, Crossed Over and Double Blind.NCT05809414
Brazilian trial of Amantadine for disorders of consciousness after intracranial bleeding due to aneurysm ruptureAmantadine for disorders of consciousness after Aneurysmal Subarachnoid HemorrhageRBR-6789t4v
The Effect of Amantadine on Post-COVD-19 FatigueThe Effect of Amantadine on Post-COVD-19 Fatigue: a Clinical TrialNCT05667077
Antihistamines, Amantadine and Evolution of the SARS-CoV-2 InfectionEvaluation of Treatments With Antihistamines and Amantadine in the Evolution of the SARS-CoV-2 InfectionNCT05504057
AmaNtadine for NeuroenhancEment in acutE patients Study - A prospective pilot proof of concept phase IIb study in intensive and intermediate care unit patients (ANNES)AmaNtadine for NeuroenhancEment in acutE patients Study - A prospective pilot proof of concept phase IIb study in intensive and intermediate care unit patients (ANNES)EUCTR2022-002418-18-DE
Amantadine for Neuroenhancement in Acute Patients StudyAmantadine for Neuroenhancement in Acute Patients Study - A Prospective Pilot Proof of Concept Phase IIb Study in Intensive and Intermediate Care Unit PatientsNCT05479032
Effect of acupuncture in relieving fatigue of multiple sclerosisComparison study between the effect of amantadine and acupuncture in relieving fatigue in multiple sclerosis patients (randomized controlled trial)IRCT20210718051931N1
Quantification of the Antidyskinetic Effect of Amantadine and Topiramate in Parkinson's DiseaseQuantification of the Antidyskinetic Effect of Amantadine and Topiramate in Parkinson's DiseaseNCT00794313
Add on amantadine for sub acute sclerosing panencephalitis in children and adolescentsEvaluation of efficacy of add on oral amantadine in children and adolescents with subacute sclerosing panencephalitis aged less than 18years: A randomized controlled trial - nilCTRI/2025/04/085165
Amantadine in bipolar depressionEvaluating effect of Amantadine adjuvant therapy on depression index of bipolar patientsIRCT20100127003210N32
Bioequivalence study of Amantadine 100 mg capsuleIn vivo bioequivalence study of Amantadine 100 mg capsule manufactured by Aani Darman Co. compared with innovator productIRCT20210519051345N82
A Study Comparing Propranolol and Amantadine for Reducing Tremors in People With Parkinson's DiseaseComparative Efficacy and Safety of Propranolol Versus Amantadine in Controlling Tremors in Parkinson's Disease: A Randomized Controlled TrialNCT07113015
Perioperative Treatment of Parkinsonian Patients With Parenteral AmantadinePerioperative Treatment of Parkinsonian Patients With Parenteral AmantadineNCT00600093
Utility of Amantadine Hydrochloride in the Treatment of Post-traumatic IrritabilityUtility of Amantadine Hydrochloride in the Treatment of Post-traumatic Irritability: A Randomized, Double-Blind, Placebo-Controlled TrialNCT00627250
Amantadine for Treatment of Symptoms of the Post-traumatic Confusional StateAmantadine Hydrochloride for Treatment of Symptoms of the Post-traumatic Confusional State Among Neurorehabilitation Admissions With TBI: A Randomized, Double-Blind, Placebo-Controlled TrialNCT00693121
A randomized, double-blind, placebo-controlled, cross-over, multi-center study concerning the efficacy and safety of amantadine hydrochloride in treatment of dyskinesias in Parkinson's diseaseA randomized, double-blind, placebo-controlled, cross-over, multi-center study concerning the efficacy and safety of amantadine hydrochloride in treatment of dyskinesias in Parkinson's disease - The usefulness of amantadine hydrochloride in treatment of dyskinesias in Parkinson's diseaseJPRN-UMIN000000780
Safety and Pharmacokinetic Effects of Oseltamivir Alone or in Combination With AmantadineAn Open-Label, Multiple Dose, Randomized, Three-Period Crossover Study in Healthy Volunteers to Evaluate the Effect of co-Administration of Amantadine 100 mg BID and Oseltamivir 75 mg BID on the Pharmacokinetic Properties of Amantadine and Oseltamivir.NCT00416962
Assessment of Safety and Efficacy of Therapy for the Prevention of Weight Gain Associated With OlanzapineThe Assessment of the Safety, Efficacy, and Practicality of an Algorithm Including Amantadine, Metformin and Zonisamide for the Prevention of Olanzapine-Associated Weight Gain in Outpatients With SchizophreniaNCT00401973
Retreatment of chronic hepatitis C patients with pegylated interferon (IFN), ribavirin and amantadine; a pilot study to establish if initial drop in viral load is predictive for sustained virological responseRetreatment of chronic hepatitis C patients with pegylated interferon (IFN), ribavirin and amantadine; a pilot study to establish if initial drop in viral load is predictive for sustained virological responseISRCTN81536220
Study of Amantadine for Weight Stabilization During Olanzapine TreatmentDouble Blind Placebo Controlled Investigation of Amantadine for Retarding Weight Gain in First Episode Adlt Psychotic Subjects Beginning Therapy With Olanzapine.NCT00287352
Retreatment of chronic hepatitis C patients with pegylated interferon, ribavirin and amantadine; A pilot study to establishif initial drop in viral load is predictive for sustained virological response.Retreatment of chronic hepatitis C patients with pegylated interferon, ribavirin and amantadine; A pilot study to establishif initial drop in viral load is predictive for sustained virological response.NL-OMON27702
Peginterferon Alfa-2a Plus Ribavirin Plus Amantadine for the Treatment of Hepatitis C Infected PatientsRandomized Placebo-Controlled Trial of a Triple Therapy Combining Peginterferon Alfa-2a Plus Ribavirin Plus Amantadine Versus Peginterferon Alfa-2a Plus Ribavirin Plus Placebo in Hepatitis C-Infected Patients Non Responders to a First-Line Therapy of Interferon and RibavirinNCT00221624
Amantadine and Temporal Discrimination in Patients With Traumatic Brain Injury (TBI)Amantadine and Temporal Discrimination in Patients With Traumatic Brain InjuryNCT00800514
Effectiveness of Amantadine and Propranolol for Treating Cocaine Dependence - 2A Double-Blind, Placebo Controlled Trial of Propranolol and Amantadine for the Treatment of Cocaine Dependent Subjects With Severe Cocaine Withdrawal SymptomsNCT00158132
Study on chronic hepatitis Ctreatment with interferon alpha, ribavirin and amantadine in naive patients.Study on chronic hepatitis Ctreatment with interferon alpha, ribavirin and amantadine in naive patients.NL-OMON20761
Peginterferon Alfa-2a, Ribavirin, Amantadine/Placebo in Hepatitis C Virus (HCV)-Genotype-1-Infection (PRAMA)Randomized, Multi-Center, Partially Placebo-Controlled Phase IV-Study to Compare Efficacy and Tolerability of 48-Week Combined Therapy With Peginterferon Alfa-2a, Ribavirin and Amantadine Sulphate Versus Placebo in Untreated Patients With Chronic Hepatitis C Virus-Genotype-1-InfectionNCT00127777
Amantadine for the Treatment of Behavioral Disturbance in Frontotemporal Dementia (FTD)Amantadine for the Treatment of Behavioral Disturbance in Frontotemporal Dementia (FTD)NCT00127114
Triple Therapy With Peg-Interferon Alfa-2b/Ribavirin Plus Amantadine Compared to Standard Peg-Interferon Alfa-2b/Ribavirin for Previous Hepatitis C Virus (HCV) Non RespondersTriple Therapy With Peg-Interferon Alfa-2b/Ribavirin Plus Amantadine Compared to Standard Peg-Interferon Alfa-2b/Ribavirin for Previous HCV Non Responders ANRSHC03 BITRINCT00122629
Treatment of Huntington's Chorea With AmantadineNMDA-Receptor Blockade in Huntington's ChoreaNCT00001930
Rapid Evaluation of Amantadine for Treatment of Cocaine Abuse/Dependence - 4Rapid Evaluation of Cocaine Pharmacotherapies (Amantadine)NCT00000301
COMBINA. Efficacité et tolérance des bithérapies oseltamivir + zanamivir ou oseltamivir + amantadine en comparaison avec la monothérapie oseltamivir dans le traitement de la grippe saisonnière A - COMBINACOMBINA. Efficacité et tolérance des bithérapies oseltamivir + zanamivir ou oseltamivir + amantadine en comparaison avec la monothérapie oseltamivir dans le traitement de la grippe saisonnière A - COMBINAEUCTR2008-004543-11-FR
Adding Amantadine or Duloxetine to Pregabalin on Occurrence of Post Mastectomy Pain SyndromeThe Effect of Adding Amantadine or Duloxetine to Pregabalin on Occurrence of Post Mastectomy Pain Syndrome; Randomized Controlled StudyNCT07421427
The effect of amantadine on cognitive dysfunction and quality of life in adults with traumatic brain injury.Investigating the effectiveness of amantadine in improving cognitive dysfunction and improving quality of life in adults with moderate traumatic brain injurIRCT20151123025202N50
Intervention of early use of amantadine on the outcome of patients with diquat poisoningIntervention of early use of amantadine on the outcome of patients with diquat poisoningChiCTR2500109316
Study on Chronic Hepatitis C Treatment With Interferon Alpha, Ribavirin and Amantadine in Naive PatientsStudy on Chronic Hepatitis C Treatment With Interferon Alpha, Ribavirin and Amantadine in Naive PatientsNCT00146016
Amantadine in methamphetamine-dependent patientsThe assessment of amantadine add-on therapy effects on craving and relapse reduction among patients with methamphetamine dependence.IRCT20090801002266N16
Adding Amantadine to Pregabalin on Occurrence of Post-thoracotomy Pain SyndromeEffectiveness of Adding Amantadine to Pregabalin on Occurrence of Post-thoracotomy Pain Syndrome; Randomized Controlled StudyNCT06833203
Comparison of Antidepressant Augmentation With Amantadine vs Pramipexole vs Quetiapine in Treatment Resistant DepressionComparative Efficacy of Antidepressant Augmentation With Amantadine vs Pramipexole vs Quetiapine in Treatment-resistant Unipolar Depression: A Randomized Controlled Trial.NCT04936126
The Use of Amantadine in the Prevention of Progression and Treatment of COVID-19 SymptomsThe Use of Amantadine in the Prevention of Progression and Treatment of COVID-19 Symptoms in Patients Infected With the SARS-CoV-2 VirusNCT04854759
The use of amantadine in the prevention of progression and treatment of COVID-19 symptoms in patients infected with the SARS-CoV-2 virusThe use of amantadine in the prevention of progression and treatment of COVID-19 symptoms in patients infected with the SARS-CoV-2 virus - COV-PREVENTEUCTR2021-001144-98-PL
Efficacy of Add-on Amantadine to clonidine on severity of opioid withdrawal symptoms.Evaluation the efficacy of Add-on Amantadine to clonidine on severity of opioid withdrawal symptoms.IRCT20090801002266N15
An effectiveness and safety comparison study of N-acetylcysteine and amantadine on fatigue and Disability and quality of life of multiple sclerotic patientsClinical trial comparing the efficacy and safety of N-acetylcysteine and amantadine on fatigue and disability and quality of life of patients with MSIRCT20201216049736N1
efficacy of amantadine vs Ropinirole in Restless legs syndromeComparison of Amantadine vs. Ropinirole in Restless legs syndrome: A single blind Randomized Controlled exploratory trialCTRI/2020/11/029296
Promoting Recovery After STroke with AmantadinePromoting Recovery After STroke with AmantadineNCT05140148
Amantadine Sulphate versus magnesium sulfate on Traumatic Brain Injury.Comparative Study between the Efficacy of Amantadine Sulphate versus magnesium sulfate on Traumatic Brain Injury. A prospective randomized trialPACTR202009761063655
Impact of Amantadine on Traumatic Brain InjuryPotential Impact of Amantadine on Traumatic Brain Injury OutcomesNCT04527289
Evaluation of the Effect of Preoperative Intravenous Amantadine Sulfate on the Postoperative Early Cognitive Functions in a Elderly Patient With Laparoscopic Radical ProstatectomyEvaluation of the Effect of Preoperative Intravenous Amantadine Sulfate on the Postoperative Early Cognitive Functions in a Elderly Patient With Laparoscopic Radical ProstatectomyNCT03988010
AMANTADINE AND TRANSCRANIAL MAGNETIC STIMULATION FOR TREATING FATIGUE IN MULTIPLE SCLEROSISAMANTADINE AND TRANSCRANIAL MAGNETIC STIMULATION FOR TREATING FATIGUE IN MULTIPLE SCLEROSIS: PHASE III STUDY, CONTROLLED, RANDOMIZED, CROSSED OVER AND DOUBLE BLIND - FETEMEUCTR2021-004868-95-ES
Acetyl-Amantadine as a Biomarker in Patients With GlioblastomaAcetyl-Amantadine as a Biomarker in Patients With GlioblastomaNCT04530006
Amantadine and dalfampiridine effects on multiple sclerosisComparison of amantadine and dalfampridine efficacy in multiple sclerosis patients with fatigueIRCT20190804044429N2
Effectiveness of Yoga Comparing to Amantadine and Commitment Group Therapy in Patients with Multiple SclerosisEffectiveness of Yoga Comparing to Amantadine and Commitment Group Therapy on Fatigue and Pain and Life Quality in Patients with Multiple SclerosisIRCT20200423047176N1
Amantadine in Treating Cognitive & Motor Impairments in Adolescents and Adults With Cerebral PalsyUse of Amantadine in Treating Cognitive and Motor Impairments in Adolescents and Adults With Cerebral PalsyNCT04273737
Treatment of mild COVID-19: a randomized, double blinded, placebo controlled studyAmantadine for COVID-19: A randomized, placebo controlled, double-blinded, clinical trialEUCTR2021-001177-22-DK
effectivness of amantadine hydrocholoride on functional recovery in sever traumatic brain injeryeffectivness of amantadine hydrocholoride on functional recovery in sever traumatic brain injeryIRCT20120527009878N7
Oral Amantadine, IV Amantadine and Hemodynamic Response to LaryngoscopyOral Amantadine Versus IV Amantadine to Attenuate the Hemodynamic Response to Laryngoscopy, Tracheal Intubation and Surgical Incision and Their Effect on ß-endorphin: A Randomized Clinical TrialNCT03612921
Oral Amantadine Versus Gabapentin to Attenuate the Response to Laryngoscopy and Tracheal IntubationOral Amantadine Versus Gabapentin to Attenuate the Hemodynamic Response to Laryngoscopy and Tracheal Intubation and Their Effect on ß-endorphinNCT03172234
Amantadine Sulphate Usage in Spine Deformities Corrective Surgeries PatientsThe Implications of Amantadine Sulphate Usage in Spine Deformities Corrective Surgeries Patients as Regard Its Effect on the Duration of Wake up Test and Postoperative Opioid ConsumptionNCT03178708
Bupropion and amantadine in sexual function in patients with methadoneComparison the effect of Bupropion and Amantadine in reducing sexual dysfunction in patients taking methadoneIRCT20170606034348N5
Effects of Ondansetron versus Amantadine on fatigability in patients with multiple sclerosisEffects of Ondansetron versus Amantadine on fatigability in patients with multiple sclerosis: a randomized clinical trialIRCT20120215009014N250
The effect of zolpidem and amantadine on the level of consciousness in patients diffuse axonal injuryThe effect of zolpidem and amantadine on the level of consciousness in patients diffuse axonal injuryIRCT20191026045243N1
Clinical Study on Treatment of L-DOPA-Induced Dyskinesia With Tianqi Pingchan Granule Combined With AmantadineA Randomized, Double-blind, Placebo-controlled, Multi-center Clinical Study of Treatment of L-DOPA-Induced Dyskinesia With Tianqi Pingchan Granule Combined With AmantadineNCT04173832
Concomitant Administration of the Methylphenidate and AmantadineEvaluating the Effect of the Concomitant Administration of Methylphenidate and Amantadine on the TBI-related Outcomes: A Randomized, Double-blind, Placebo-controlled, Parallel trialIRCT20130310012776N7
Treatment of Fatigue With Methylphenidate, Modafinil and Amantadine in Multiple SclerosisTreatment of Fatigue With Methylphenidate, Modafinil and Amantadine in Multiple SclerosisNCT03185065
Citicholine-Amantadine Trial in Traumatic Brain InjuryCiticholine-Amantadine Trial in Traumatic Brain InjuryNCT03430817
Benefits of Amantadine in Patients With Coma StateNCT03443037
Effects of Amantadine on Postoperative Cognitive DysfunctionEffects of Amantadine on Postoperative Cognitive Dysfunction in Elderly Patients With Elective Abdominal SurgeryNCT03527134
Is Long-term Use of Amantadine Effective in PD?Is Long-term Use of Amantadine Effective in Parkinson Disease?NCT04260581