Medicinal Fungi Secondary Metabolite And Therapeutics (MeFSAT) is a curated database which has been constructed via literature mining followed by manual curation of information gathered from more than 900 published research articles, 6 specialized books on medicinal fungi and other existing resources.
MeFSAT database captures two different types of associations:
(a) medicinal fungi and their secondary metabolites
(b) medicinal fungi and their therapeutic uses
MeFSAT database captures 184 medicinal fungi, 1830 secondary metabolites, and 149 therapeutic uses. For the 1830 secondary metabolites in this database, we provide the two-dimensional (2D) and three-dimensional (3D) chemical structures, and have employed cheminformatics tools to compute their physicochemical properties, drug-likeliness based on multiple scoring schemes, predicted Absorption, Distribution, Metabolism, Excretion and Toxicity (ADMET) properties and molecular descriptors. In sum, MeFSAT is a dedicated database on secondary metabolites of medicinal fungi, and this resource is expected to aid natural product based drug discovery.


Secondary metabolite association



Therapeutic use association


If you use our resource, please cite the following research article:
R. P. Vivek-Ananth#, Ajaya Kumar Sahoo#, Kavyaa Kumaravel#, Karthikeyan Mohanraj, Areejit Samal*, MeFSAT: A curated natural product database specific to secondary metabolites of medicinal fungi, RSC Advances, 11:2596-2607 (2021).
# Joint-First authors; * Corresponding author.


In case you face problems, please contact Areejit Samal.


Research in the group of Areejit Samal at The Institute of Mathematical Sciences (IMSc), Chennai is financially supported by the Department of Atomic Energy (DAE) India, a Ramanujan fellowship (SB/S2/RJN-006/2014) from the Science and Engineering Research Board (SERB), Department of Science and Technology (DST) India, and a Max Planck Partner Group funded by the Max Planck Society Germany. The funders have no role in study design, prediction, analysis or decision to publish this work.


MeFSAT is primarily a curated resource on secondary metabolites of medicinal fungi. The resource also compiles reported therapeutic uses of several medicinal fungi. We are not responsible for errors or omission in published literature used to compile the information in this resource. The complied information in this resource should be strictly used for research purposes and should not be used for any self diagnosis or medical treatment. Our employers and funders have no role in design, data collection, data analysis, or decision to publish this resource.

Designed by R.P. Vivek-Ananth, M Karthikeyan and Ajaya Kumar Sahoo