Letrozole


Curated chemical-disease associations from CTD
Disease IDDisease nameReference
MESH:D000858 Anovulation PMID:28619389; PMID:37030623
MESH:D001416 Back Pain PMID:25524798
MESH:D001847 Bone Diseases PMID:34081940
MESH:D003967 Diarrhea PMID:25524798
MESH:D004195 Disease Models, Animal PMID:32298659; PMID:33359182; PMID:34081940
MESH:D005221 Fatigue PMID:25524798
MESH:D006943 Hyperglycemia PMID:33359182; PMID:33491863; PMID:37030623
MESH:D006946 Hyperinsulinism PMID:32298659
MESH:D007333 Insulin Resistance PMID:31295448; PMID:32298659; PMID:33359182; PMID:33491863
MESH:D007970 Leukopenia PMID:25524798
MESH:D008569 Memory Disorders PMID:24902786
MESH:D009503 Neutropenia PMID:25524798
MESH:D010048 Ovarian Cysts PMID:28619389
MESH:D011085 Polycystic Ovary Syndrome PMID:31295448; PMID:32298659; PMID:33359182; PMID:33491863; PMID:37030623; PMID:39032681
MESH:D011655 Pulmonary Embolism PMID:25524798
MESH:D013262 Stevens-Johnson Syndrome PMID:25811541
MESH:D015430 Weight Gain PMID:28619389; PMID:31295448; PMID:33359182; PMID:37030623; PMID:37328115; PMID:39032681
MESH:D017588 Hyperandrogenism PMID:32298659
MESH:D018149 Glucose Intolerance PMID:31295448; PMID:33359182
MESH:D019964 Mood Disorders PMID:17042891
MESH:D050171 Dyslipidemias PMID:31295448
MESH:D056128 Obesity, Abdominal PMID:31295448
MESH:D056486 Chemical and Drug Induced Liver Injury PMID:33814510
MESH:D059226 Nociceptive Pain PMID:34081940
MESH:D059350 Chronic Pain PMID:34081940

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We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.