Trichloroethylene


Curated chemical-disease associations from CTD
Disease IDDisease nameReference
MESH:D000014 Abnormalities, Drug-Induced PMID:19910388
MESH:D000419 Albuminuria PMID:32763311
MESH:D000707 Anaphylaxis PMID:22467029
MESH:D001254 Astrocytoma PMID:26505805
MESH:D001327 Autoimmune Diseases PMID:17123686; PMID:17966069; PMID:18234256; PMID:23993974; PMID:25055964; PMID:33007382
MESH:D001724 Birth Weight PMID:25413571
MESH:D001768 Blister PMID:19367038
MESH:D001943 Breast Neoplasms PMID:15986119
MESH:D002277 Carcinoma PMID:20663906
MESH:D002292 Carcinoma, Renal Cell PMID:10340905; PMID:10361587; PMID:10714214; PMID:15177666; PMID:16097165; PMID:17479278; PMID:19473641; PMID:9137812; PMID:9285043
MESH:D002761 Cholangitis PMID:25055964
MESH:D003872 Dermatitis PMID:15526526; PMID:16836882; PMID:18007983; PMID:19996547; PMID:23994554
MESH:D003873 Dermatitis, Exfoliative PMID:15256158; PMID:19647757
MESH:D003875 Drug Eruptions PMID:19351467; PMID:21055120; PMID:22728725; PMID:24960064; PMID:24974766; PMID:31150805
MESH:D003877 Dermatitis, Contact PMID:18348411
MESH:D004195 Disease Models, Animal PMID:25026505; PMID:30685357; PMID:31618666
MESH:D004244 Dizziness PMID:19367038
MESH:D004342 Drug Hypersensitivity PMID:18007983
MESH:D004487 Edema PMID:20450792; PMID:26095957; PMID:31068537; PMID:33132242
MESH:D004831 Epilepsies, Myoclonic PMID:19088417
MESH:D004890 Erythema PMID:15256158; PMID:19367038; PMID:20450792; PMID:26095957; PMID:31068537; PMID:33132242
MESH:D005234 Fatty Liver PMID:20709644; PMID:4800729
MESH:D005317 Fetal Growth Retardation PMID:25413571
MESH:D005334 Fever PMID:19367038
MESH:D005355 Fibrosis PMID:4800729
MESH:D006261 Headache PMID:19367038
MESH:D006330 Heart Defects, Congenital PMID:19910388; PMID:20186580; PMID:2229779; PMID:25847060
MESH:D006331 Heart Diseases PMID:33524428
MESH:D006505 Hepatitis PMID:18234256; PMID:18403861; PMID:18540116; PMID:18565563; PMID:21258588
MESH:D006528 Carcinoma, Hepatocellular PMID:27618143
MESH:D006529 Hepatomegaly PMID:19249323; PMID:21549800; PMID:23575800
MESH:D006935 Hypercapnia PMID:4696443
MESH:D006967 Hypersensitivity PMID:18540116; PMID:20450792; PMID:21741468; PMID:31618666; PMID:32763311
MESH:D007022 Hypotension PMID:4696443
MESH:D007154 Immune System Diseases PMID:22467029
MESH:D007249 Inflammation PMID:18234256; PMID:20709644; PMID:23575800; PMID:25026505; PMID:32763311
MESH:D007674 Kidney Diseases PMID:17285313; PMID:22728725; PMID:23037997; PMID:31068537; PMID:31618666; PMID:33132242
MESH:D007680 Kidney Neoplasms PMID:20663906; PMID:24923549
MESH:D008107 Liver Diseases PMID:19367038
MESH:D008113 Liver Neoplasms PMID:10774822; PMID:12127263; PMID:19249323; PMID:21549800
MESH:D008114 Liver Neoplasms, Experimental PMID:7955063
MESH:D008173 Lung Diseases, Obstructive PMID:15526526
MESH:D008228 Lymphoma, Non-Hodgkin PMID:21370516
MESH:D009336 Necrosis PMID:23037997; PMID:24974766
MESH:D009369 Neoplasms PMID:11911487; PMID:19549554
MESH:D009410 Nerve Degeneration PMID:33636387
MESH:D009436 Neural Tube Defects PMID:24304547
MESH:D009783 Dermatitis, Occupational PMID:16737583; PMID:16758956; PMID:19367038; PMID:19834256; PMID:22728725; PMID:24960064; PMID:24974766; PMID:29477354; PMID:30685357; PMID:33132242
MESH:D009784 Occupational Diseases PMID:23994554; PMID:8506855
MESH:D010300 Parkinson Disease PMID:18157908
MESH:D010302 Parkinson Disease, Secondary PMID:10457397
MESH:D011297 Prenatal Exposure Delayed Effects PMID:25847060
MESH:D011537 Pruritus PMID:19367038
MESH:D012595 Scleroderma, Systemic PMID:9627022
MESH:D012871 Skin Diseases PMID:18540116
MESH:D012877 Skin Manifestations PMID:31618666
MESH:D013262 Stevens-Johnson Syndrome PMID:9358112
MESH:D013959 Thyroid Diseases PMID:9891105
MESH:D014606 Uveitis, Anterior PMID:2235804
MESH:D017119 Porphyria Cutanea Tarda PMID:12719865
MESH:D017449 Dermatitis, Allergic Contact PMID:12244752; PMID:15849067; PMID:15862011; PMID:16105458; PMID:18403861
MESH:D018242 Neuroectodermal Tumors, Primitive PMID:26505805
MESH:D019693 Hepatitis, Autoimmune PMID:11006364; PMID:19254012; PMID:21084432; PMID:25026505; PMID:28369519
MESH:D020258 Neurotoxicity Syndromes PMID:8506855
MESH:D020567 Fetal Weight PMID:30468822; PMID:33599830
MESH:D034381 Hearing Loss PMID:9268609
MESH:D045743 Scleroderma, Diffuse PMID:12719865; PMID:19801256
MESH:D049188 Prenatal Injuries PMID:33599830
MESH:D051437 Renal Insufficiency PMID:32763311
MESH:D056486 Chemical and Drug Induced Liver Injury PMID:1802361; PMID:18234256; PMID:19254012; PMID:19367038; PMID:21741468; PMID:2235804; PMID:23575800; PMID:2361581; PMID:24974766; PMID:30685357; PMID:4800729; PMID:7120509

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We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.