Methimazole


Curated chemical-disease associations from CTD
Disease IDDisease nameReference
MESH:C538458 Rapidly progressive glomerulonephritis with pulmonary hemorrhage PMID:16207324
MESH:C572845 Thyroid cancer, follicular PMID:4758968
MESH:D000014 Abnormalities, Drug-Induced PMID:16440566
MESH:D000068079 Motor Disorders PMID:27413119
MESH:D000230 Adenocarcinoma PMID:4758968
MESH:D000236 Adenoma PMID:16942904; PMID:4758968
MESH:D000370 Ageusia PMID:7076071
MESH:D000380 Agranulocytosis PMID:12232461; PMID:15072706; PMID:16553037; PMID:18816182; PMID:20144635; PMID:2523194; PMID:4172680
MESH:D000741 Anemia, Aplastic PMID:10085704; PMID:10544668; PMID:15072706; PMID:15493589; PMID:1642096; PMID:16553037; PMID:171299; PMID:18816182; PMID:20144635; PMID:3437520; PMID:6188311; PMID:9086574; PMID:9245107; PMID:9777751
MESH:D000857 Olfaction Disorders PMID:639655; PMID:8838641
MESH:D001168 Arthritis PMID:15785249
MESH:D001724 Birth Weight PMID:29990518; PMID:34757178
MESH:D002277 Carcinoma PMID:16942904
MESH:D002754 Choanal Atresia PMID:11745832; PMID:16440566
MESH:D002779 Cholestasis PMID:12467281; PMID:17724899; PMID:20960257; PMID:2271514; PMID:34788025
MESH:D002780 Cholestasis, Intrahepatic PMID:19534646; PMID:20707932; PMID:3804181; PMID:4641547; PMID:8817448
MESH:D003875 Drug Eruptions PMID:20168071
MESH:D004195 Disease Models, Animal PMID:27421576
MESH:D004342 Drug Hypersensitivity PMID:3405562; PMID:6188311
MESH:D004476 Ectodermal Dysplasia PMID:11038449
MESH:D004844 Epistaxis PMID:15493589
MESH:D004933 Esophageal Atresia PMID:11745832
MESH:D005076 Exanthema PMID:15785249; PMID:20168071; PMID:2523194; PMID:9773944
MESH:D005221 Fatigue PMID:15493589
MESH:D005334 Fever PMID:15785249
MESH:D005767 Gastrointestinal Diseases PMID:2523194
MESH:D005921 Glomerulonephritis PMID:8956314
MESH:D006042 Goiter PMID:20036711
MESH:D006406 Hematoma PMID:15493589
MESH:D006470 Hemorrhage PMID:11802538; PMID:16553037
MESH:D006505 Hepatitis PMID:1937386
MESH:D006529 Hepatomegaly PMID:28108177
MESH:D006932 Hyperbilirubinemia PMID:14982270
MESH:D006965 Hyperplasia PMID:4758968
MESH:D006980 Hyperthyroidism PMID:27413119
MESH:D006984 Hypertrophy PMID:4758968
MESH:D006996 Hypocalcemia PMID:1657745
MESH:D007003 Hypoglycemia PMID:29990518
MESH:D007035 Hypothermia PMID:26177832
MESH:D007037 Hypothyroidism PMID:11521740; PMID:12587721; PMID:1387618; PMID:18031379; PMID:20808432; PMID:21314467; PMID:25539664; PMID:8921835
MESH:D007565 Jaundice PMID:12467281
MESH:D007805 Language Development Disorders PMID:16440566
MESH:D007859 Learning Disabilities PMID:27413119
MESH:D007970 Leukopenia PMID:20144635; PMID:8548997
MESH:D008107 Liver Diseases PMID:18383979
MESH:D008181 Lupus Nephritis PMID:14723259
MESH:D009069 Movement Disorders PMID:3754623
MESH:D009120 Muscle Cramp PMID:1657745
MESH:D009157 Myasthenia Gravis PMID:1798220; PMID:20635587
MESH:D009336 Necrosis PMID:27421576
MESH:D009404 Nephrotic Syndrome PMID:434980
MESH:D010198 Pancytopenia PMID:15493589; PMID:6188311
MESH:D011297 Prenatal Exposure Delayed Effects PMID:11745832; PMID:16440566; PMID:27413119; PMID:29990518; PMID:3754623
MESH:D011507 Proteinuria PMID:434980
MESH:D011537 Pruritus PMID:12467281; PMID:14982270; PMID:20960257
MESH:D012640 Seizures PMID:11712661
MESH:D012872 Skin Diseases, Vesiculobullous PMID:12353714
MESH:D013064 Speech Disorders PMID:16440566
MESH:D013651 Taste Disorders PMID:1245162; PMID:639655
MESH:D013921 Thrombocytopenia PMID:15493589; PMID:20144635
MESH:D013959 Thyroid Diseases PMID:21800831; PMID:34757178
MESH:D013964 Thyroid Neoplasms PMID:16942904
MESH:D013971 Thyrotoxicosis PMID:1657745
MESH:D014581 Urticaria PMID:15785249
MESH:D014657 Vasculitis PMID:16207347; PMID:8548997
MESH:D015209 Cholangitis, Sclerosing PMID:8817448
MESH:D015431 Weight Loss PMID:29990518; PMID:34757178
MESH:D016171 Torsades de Pointes PMID:11707056
MESH:D017093 Liver Failure PMID:20707932
MESH:D017114 Liver Failure, Acute PMID:2271514
MESH:D017563 Lung Diseases, Interstitial PMID:8956314
MESH:D018366 Vasculitis, Leukocytoclastic, Cutaneous PMID:16207347
MESH:D018476 Hypokinesia PMID:25962731
MESH:D018771 Arthralgia PMID:15785249; PMID:16207347; PMID:2523194; PMID:505096
MESH:D018908 Muscle Weakness PMID:505096
MESH:D019465 Craniofacial Abnormalities PMID:16440566; PMID:25962731
MESH:D020293 Vasculitis, Central Nervous System PMID:18788922
MESH:D041781 Jaundice, Obstructive PMID:14982270; PMID:1687933; PMID:17493435; PMID:20960257
MESH:D047508 Massive Hepatic Necrosis PMID:2484903
MESH:D048550 Hepatic Insufficiency PMID:20960098
MESH:D055953 Microscopic Polyangiitis PMID:16207324
MESH:D056486 Chemical and Drug Induced Liver Injury PMID:1245162; PMID:12467281; PMID:17493435; PMID:17724899; PMID:20960098; PMID:22407903; PMID:2271514; PMID:24085192; PMID:2523194; PMID:26177832; PMID:27421576; PMID:28437613; PMID:29990518; PMID:33814510; PMID:34788025
MESH:D056648 Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis PMID:11802538; PMID:12353714; PMID:15175822; PMID:20061292
MESH:D064420 Drug-Related Side Effects and Adverse Reactions PMID:434980

DISCLAIMER

We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.