Epoxiconazole

Target genes for Epoxiconazole is obtained based on ToxCast assay component endpoints.
Chemical nameGene identifierToxCast assay component endpoint name
EpoxiconazoleNACEETOX_H295R_PROG_dn
EpoxiconazoleESR1CEETOX_H295R_ESTRONE_dn
EpoxiconazoleESR1CEETOX_H295R_TESTO_dn
EpoxiconazoleESR1CEETOX_H295R_ESTRADIOL_dn
EpoxiconazoleNACEETOX_H295R_TESTO_dn
EpoxiconazoleNACEETOX_H295R_ANDR_dn
EpoxiconazoleCYP1A2NVS_ADME_hCYP1A2
EpoxiconazoleCYP2C19NVS_ADME_hCYP2C19
EpoxiconazoleCYP2C9NVS_ADME_hCYP2C9
EpoxiconazoleCYP3A4NVS_ADME_hCYP3A4
EpoxiconazoleCYP19A1NVS_ADME_hCYP19A1
EpoxiconazoleCYP19A1TOX21_Aromatase_Inhibition
EpoxiconazoleAHRATG_Ahr_CIS_up
EpoxiconazoleESR1TOX21_ERa_BLA_Antagonist_ratio
EpoxiconazoleESR1OT_ER_ERaERb_1440
EpoxiconazoleESR1TOX21_ERa_LUC_VM7_Antagonist_0.5nM_E2
EpoxiconazoleESR1CEETOX_H295R_ESTRADIOL_dn
EpoxiconazoleESR1OT_ER_ERaERa_1440
EpoxiconazoleESR1OT_ER_ERaERa_0480
EpoxiconazoleESR1OT_ER_ERaERb_0480
EpoxiconazoleESR1TOX21_ERa_LUC_VM7_Antagonist_0.1nM_E2
EpoxiconazoleESR1CEETOX_H295R_ESTRONE_dn
EpoxiconazoleESR2CEETOX_H295R_ESTRADIOL_dn
EpoxiconazoleESR2OT_ER_ERbERb_0480
EpoxiconazoleESR2OT_ER_ERbERb_1440
EpoxiconazoleESR2TOX21_ERb_BLA_Antagonist_ratio
EpoxiconazoleESR2OT_ER_ERaERb_1440
EpoxiconazoleESR2CEETOX_H295R_ESTRONE_dn
EpoxiconazoleESR2OT_ER_ERaERb_0480
EpoxiconazoleESRRATOX21_ERR_Antagonist
EpoxiconazoleESRRATOX21_PGC_ERR_Antagonist
EpoxiconazoleNR3C1CEETOX_H295R_DOC_up
EpoxiconazoleNR3C1CEETOX_H295R_11DCORT_dn
EpoxiconazoleNR3C1CEETOX_H295R_CORTISOL_dn
EpoxiconazoleARCEETOX_H295R_ANDR_dn
EpoxiconazoleARCEETOX_H295R_TESTO_dn
EpoxiconazoleAROT_AR_ARSRC1_0960
EpoxiconazoleARTOX21_AR_BLA_Antagonist_ratio
EpoxiconazoleARTOX21_AR_LUC_MDAKB2_Antagonist_0.5nM_R1881
EpoxiconazoleARTOX21_AR_LUC_MDAKB2_Antagonist_10nM_R1881
EpoxiconazoleESR1CEETOX_H295R_TESTO_dn
EpoxiconazoleESR1CEETOX_H295R_ESTRONE_dn
EpoxiconazoleESR1CEETOX_H295R_ESTRADIOL_dn
EpoxiconazoleNACEETOX_H295R_ESTRADIOL_dn
EpoxiconazoleNACEETOX_H295R_TESTO_dn
EpoxiconazoleNACEETOX_H295R_ESTRONE_dn
EpoxiconazoleSMAD1ATG_BRE_CIS_up
EpoxiconazoleARCEETOX_H295R_TESTO_dn
EpoxiconazoleARCEETOX_H295R_ANDR_dn
EpoxiconazoleNR3C2CEETOX_H295R_DOC_up
EpoxiconazoleNR3C2CEETOX_H295R_CORTISOL_dn
EpoxiconazoleNR3C2CEETOX_H295R_11DCORT_dn
EpoxiconazoleMTF1ATG_MRE_CIS_up
EpoxiconazoleNFE2L2ATG_NRF2_ARE_CIS_up
EpoxiconazoleLEF1ATG_TCF_b_cat_CIS_dn
EpoxiconazolePGRCEETOX_H295R_OHPREG_dn
EpoxiconazolePGRTOX21_PR_BLA_Antagonist_ratio
EpoxiconazolePGRCEETOX_H295R_OHPROG_dn
EpoxiconazolePGRCEETOX_H295R_PROG_dn
EpoxiconazoleRORAATG_RORE_CIS_up
EpoxiconazoleRORBATG_RORE_CIS_up
EpoxiconazoleRORCATG_RORE_CIS_up
EpoxiconazoleSREBF1ATG_SREBP_CIS_up
EpoxiconazoleTCF7ATG_TCF_b_cat_CIS_dn
EpoxiconazoleTCF7L2ATG_TCF_b_cat_CIS_dn
EpoxiconazoleVDRATG_VDRE_CIS_up
EpoxiconazoleNACEETOX_H295R_TESTO_dn
EpoxiconazoleNACEETOX_H295R_ANDR_dn
EpoxiconazoleTCF7L1ATG_TCF_b_cat_CIS_dn
EpoxiconazoleNR1I2ATG_PXR_TRANS_up
EpoxiconazoleNR1I2ATG_PXRE_CIS_up
EpoxiconazoleNR1H4OT_FXR_FXRSRC1_1440
EpoxiconazoleNR1H4OT_FXR_FXRSRC1_0480

DISCLAIMER

We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.