Finasteride

Target genes for Finasteride is obtained based on ToxCast assay component endpoints.
Chemical nameGene identifierToxCast assay component endpoint name
FinasterideNR1H3ATG_LXRa_TRANS_up
FinasterideNACEETOX_H295R_PROG_dn
FinasterideESR1CEETOX_H295R_ESTRONE_dn
FinasterideESR1CEETOX_H295R_ESTRADIOL_dn
FinasterideESR1CEETOX_H295R_ESTRADIOL_dn
FinasterideESR1CEETOX_H295R_ESTRONE_dn
FinasterideESR1OT_ER_ERaERa_1440
FinasterideESR2CEETOX_H295R_ESTRONE_dn
FinasterideESR2CEETOX_H295R_ESTRADIOL_dn
FinasterideESRRATOX21_PGC_ERR_Antagonist
FinasterideESRRATOX21_ERR_Antagonist
FinasterideNR3C1CEETOX_H295R_CORTISOL_dn
FinasterideNR3C1CEETOX_H295R_DOC_dn
FinasterideNR3C1CEETOX_H295R_11DCORT_dn
FinasterideIRF1ATG_ISRE_CIS_dn
FinasterideARTOX21_AR_LUC_MDAKB2_Antagonist_0.5nM_R1881
FinasterideARTOX21_AR_BLA_Antagonist_ratio
FinasterideARACEA_AR_antagonist_80hr
FinasterideESR1CEETOX_H295R_ESTRADIOL_dn
FinasterideESR1CEETOX_H295R_ESTRONE_dn
FinasterideNACEETOX_H295R_ESTRONE_dn
FinasterideNACEETOX_H295R_ESTRADIOL_dn
FinasterideNR3C2CEETOX_H295R_CORTISOL_dn
FinasterideNR3C2CEETOX_H295R_11DCORT_dn
FinasterideNR3C2CEETOX_H295R_DOC_dn
FinasterideMTF1ATG_MRE_CIS_up
FinasterideNFE2L2TOX21_ARE_BLA_agonist_ratio
FinasterideNFE2L2ATG_NRF2_ARE_CIS_up
FinasterideLEF1ATG_TCF_b_cat_CIS_dn
FinasteridePGRCEETOX_H295R_OHPREG_up
FinasteridePGRCEETOX_H295R_PROG_dn
FinasteridePGRCEETOX_H295R_OHPROG_dn
FinasteridePGRTOX21_PR_BLA_Antagonist_ratio
FinasteridePPARDATG_PPARd_TRANS_up
FinasterideRARAATG_RARa_TRANS_dn
FinasterideTCF7ATG_TCF_b_cat_CIS_dn
FinasterideTCF7L2ATG_TCF_b_cat_CIS_dn
FinasterideTP53ATG_p53_CIS_dn
FinasterideTCF7L1ATG_TCF_b_cat_CIS_dn
FinasterideNR1I2ATG_PXR_TRANS_up
FinasterideNR1I2ATG_PXRE_CIS_up
FinasterideNR1H4OT_FXR_FXRSRC1_1440
FinasterideNR1H4TOX21_FXR_BLA_antagonist_ratio

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