Ethinylestradiol

Target genes for Ethinylestradiol is obtained based on ToxCast assay component endpoints.
Chemical nameGene identifierToxCast assay component endpoint name
EthinylestradiolNR1H3ATG_DR4_LXR_CIS_dn
EthinylestradiolNACEETOX_H295R_PROG_dn
EthinylestradiolCREB3ATG_CRE_CIS_up
EthinylestradiolADORA2ANVS_GPCR_hAdoRA2a
EthinylestradiolCSF1BSK_LPS_MCSF_down
EthinylestradiolCYP2C19NVS_ADME_hCYP2C19
EthinylestradiolCYP2C9NVS_ADME_hCYP2C9
EthinylestradiolCYP2C18NVS_ADME_hCYP2C18
EthinylestradiolCYP2J2NVS_ADME_hCYP2J2
EthinylestradiolCYP3A4NVS_ADME_hCYP3A4
EthinylestradiolCYP3A5NVS_ADME_hCYP3A5
EthinylestradiolEGR1ATG_EGR_CIS_up
EthinylestradiolESR1NVS_NR_hER
EthinylestradiolESR1OT_ERa_EREGFP_0120
EthinylestradiolESR1ACEA_ER_80hr
EthinylestradiolESR1OT_ER_ERaERb_0480
EthinylestradiolESR1TOX21_ERa_LUC_VM7_Antagonist_0.1nM_E2
EthinylestradiolESR1OT_ER_ERaERa_1440
EthinylestradiolESR1OT_ER_ERaERa_0480
EthinylestradiolESR1ATG_ERE_CIS_up
EthinylestradiolESR1TOX21_ERa_BLA_Agonist_ratio
EthinylestradiolESR1TOX21_ERa_LUC_VM7_Agonist
EthinylestradiolESR1OT_ERa_EREGFP_0480
EthinylestradiolESR1ATG_ERa_TRANS_up
EthinylestradiolESR1OT_ER_ERaERb_1440
EthinylestradiolESR2OT_ER_ERbERb_1440
EthinylestradiolESR2OT_ER_ERaERb_1440
EthinylestradiolESR2TOX21_ERb_BLA_Agonist_ratio
EthinylestradiolESR2OT_ER_ERbERb_0480
EthinylestradiolESR2TOX21_ERb_BLA_Antagonist_ratio
EthinylestradiolESR2OT_ER_ERaERb_0480
EthinylestradiolESRRATOX21_ERR_Antagonist
EthinylestradiolF3BSK_3C_TissueFactor_down
EthinylestradiolFOXO1ATG_FoxO_CIS_dn
EthinylestradiolFOXO3ATG_FoxO_CIS_dn
EthinylestradiolGLI1ATG_GLI_CIS_up
EthinylestradiolNR3C1CEETOX_H295R_11DCORT_dn
EthinylestradiolNR3C1CEETOX_H295R_CORTIC_dn
EthinylestradiolNR3C1CEETOX_H295R_DOC_dn
EthinylestradiolNR3C1TOX21_GR_BLA_Antagonist_ratio
EthinylestradiolNR3C1NVS_NR_hGR
EthinylestradiolNR3C1CEETOX_H295R_CORTISOL_dn
EthinylestradiolHIF1AATG_HIF1a_CIS_up
EthinylestradiolHLA-DRABSK_3C_HLADR_down
EthinylestradiolHSF1ATG_HSE_CIS_up
EthinylestradiolIL1ABSK_LPS_IL1a_down
EthinylestradiolIL6BSK_CASM3C_IL6_down
EthinylestradiolCXCL8BSK_3C_IL8_down
EthinylestradiolCXCL8BSK_LPS_IL8_down
EthinylestradiolIRF1ATG_ISRE_CIS_dn
EthinylestradiolARTOX21_AR_LUC_MDAKB2_Antagonist_0.5nM_R1881
EthinylestradiolARTOX21_AR_LUC_MDAKB2_Antagonist_10nM_R1881
EthinylestradiolARTOX21_AR_BLA_Antagonist_ratio
EthinylestradiolARTOX21_AR_BLA_Agonist_ratio
EthinylestradiolARACEA_AR_agonist_80hr
EthinylestradiolAROT_AR_ARSRC1_0960
EthinylestradiolAROT_AR_ARSRC1_0480
EthinylestradiolARACEA_AR_antagonist_80hr
EthinylestradiolARNVS_NR_hAR
EthinylestradiolLDLRBSK_CASM3C_LDLR_up
EthinylestradiolSMAD1ATG_BRE_CIS_up
EthinylestradiolNR3C2CEETOX_H295R_CORTIC_dn
EthinylestradiolNR3C2CEETOX_H295R_DOC_dn
EthinylestradiolNR3C2CEETOX_H295R_CORTISOL_dn
EthinylestradiolNR3C2CEETOX_H295R_11DCORT_dn
EthinylestradiolMMP1BSK_BE3C_MMP1_down
EthinylestradiolMTF1ATG_MRE_CIS_up
EthinylestradiolNFIAATG_NFI_CIS_up
EthinylestradiolNFKB1ATG_NF_kB_CIS_up
EthinylestradiolOPRM1NVS_GPCR_hOpiate_mu
EthinylestradiolPAX6ATG_Pax6_CIS_up
EthinylestradiolLEF1ATG_TCF_b_cat_CIS_dn
EthinylestradiolPGRCEETOX_H295R_PROG_dn
EthinylestradiolPGRTOX21_PR_BLA_Antagonist_ratio
EthinylestradiolPGRCEETOX_H295R_OHPROG_dn
EthinylestradiolPGRCEETOX_H295R_OHPREG_up
EthinylestradiolPGRTOX21_PR_BLA_Agonist_ratio
EthinylestradiolPGRNVS_NR_hPR
EthinylestradiolPLAURBSK_4H_uPAR_down
EthinylestradiolPLAURBSK_3C_uPAR_down
EthinylestradiolPOU2F1ATG_Oct_MLP_CIS_up
EthinylestradiolRARAATG_DR5_CIS_up
EthinylestradiolRARBATG_DR5_CIS_up
EthinylestradiolRARGATG_DR5_CIS_up
EthinylestradiolRORAATG_RORE_CIS_up
EthinylestradiolRORBATG_RORE_CIS_up
EthinylestradiolRORCATG_RORE_CIS_up
EthinylestradiolSAA1BSK_CASM3C_SAA_up
EthinylestradiolCCL2BSK_LPS_MCP1_down
EthinylestradiolCCL2BSK_3C_MCP1_down
EthinylestradiolCCL2BSK_SAg_MCP1_down
EthinylestradiolCCL2BSK_CASM3C_MCP1_up
EthinylestradiolSELEBSK_3C_Eselectin_down
EthinylestradiolSLC6A2NVS_TR_hNET
EthinylestradiolSLC6A3NVS_TR_hDAT
EthinylestradiolSLC6A4NVS_TR_hSERT
EthinylestradiolSOX1ATG_Sox_CIS_up
EthinylestradiolSP1ATG_Sp1_CIS_up
EthinylestradiolSRCNVS_ENZ_hSRC
EthinylestradiolSREBF1ATG_SREBP_CIS_up
EthinylestradiolTCF7ATG_TCF_b_cat_CIS_dn
EthinylestradiolTCF7L2ATG_TCF_b_cat_CIS_dn
EthinylestradiolTFAP2AATG_AP_2_CIS_dn
EthinylestradiolTFAP2BATG_AP_2_CIS_dn
EthinylestradiolTGFB1BSK_BE3C_TGFb1_down
EthinylestradiolTSPONVS_MP_hPBR
EthinylestradiolTNFBSK_LPS_TNFa_up
EthinylestradiolTP53APR_HepG2_p53Act_72h_up
EthinylestradiolTP53TOX21_p53_BLA_p3_ratio
EthinylestradiolTP53TOX21_p53_BLA_p2_ratio
EthinylestradiolTP53TOX21_p53_BLA_p1_ratio
EthinylestradiolTP53TOX21_p53_BLA_p5_ratio
EthinylestradiolTP53ATG_p53_CIS_dn
EthinylestradiolTP53TOX21_p53_BLA_p4_ratio
EthinylestradiolTP53APR_HepG2_p53Act_24h_up
EthinylestradiolTSHRTOX21_TSHR_Agonist_ratio
EthinylestradiolNR1H2ATG_DR4_LXR_CIS_dn
EthinylestradiolUSF1ATG_E_Box_CIS_dn
EthinylestradiolVCAM1BSK_LPS_VCAM1_down
EthinylestradiolVDRATG_VDRE_CIS_up
EthinylestradiolXBP1ATG_Xbp1_CIS_up
EthinylestradiolTCF7L1ATG_TCF_b_cat_CIS_dn
EthinylestradiolTFAP2DATG_AP_2_CIS_dn
EthinylestradiolNR1I2ATG_PXRE_CIS_up
EthinylestradiolNR1I2ATG_PXR_TRANS_up
EthinylestradiolNR1I2NVS_NR_hPXR
EthinylestradiolNR1I3NVS_NR_hCAR_Antagonist
EthinylestradiolNR1I3ATG_CAR_TRANS_dn
EthinylestradiolNR1I3TOX21_CAR_Antagonist
EthinylestradiolNR1H4ATG_IR1_CIS_dn
EthinylestradiolNR1H4OT_FXR_FXRSRC1_1440
EthinylestradiolNR1H4TOX21_FXR_BLA_antagonist_ratio
EthinylestradiolNR1H4OT_FXR_FXRSRC1_0480

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