Methyltestosterone

Target genes for Methyltestosterone is obtained based on ToxCast assay component endpoints.
Chemical nameGene identifierToxCast assay component endpoint name
MethyltestosteroneNR1H3ATG_DR4_LXR_CIS_dn
MethyltestosteroneESR1CEETOX_H295R_ESTRADIOL_dn
MethyltestosteroneESR1CEETOX_H295R_ESTRONE_dn
MethyltestosteroneCYP2C19NVS_ADME_hCYP2C19
MethyltestosteroneESR1ATG_ERa_TRANS_up
MethyltestosteroneESR1ATG_ERE_CIS_up
MethyltestosteroneESR1OT_ER_ERaERb_1440
MethyltestosteroneESR1CEETOX_H295R_ESTRADIOL_dn
MethyltestosteroneESR1TOX21_ERa_LUC_VM7_Agonist
MethyltestosteroneESR1OT_ER_ERaERb_0480
MethyltestosteroneESR1ACEA_ER_80hr
MethyltestosteroneESR1CEETOX_H295R_ESTRONE_dn
MethyltestosteroneESR1TOX21_ERa_BLA_Agonist_ratio
MethyltestosteroneESR1TOX21_ERa_LUC_VM7_Antagonist_0.1nM_E2
MethyltestosteroneESR1NVS_NR_hER
MethyltestosteroneESR2OT_ER_ERbERb_1440
MethyltestosteroneESR2OT_ER_ERaERb_0480
MethyltestosteroneESR2CEETOX_H295R_ESTRONE_dn
MethyltestosteroneESR2OT_ER_ERaERb_1440
MethyltestosteroneESR2OT_ER_ERbERb_0480
MethyltestosteroneESR2CEETOX_H295R_ESTRADIOL_dn
MethyltestosteroneESR2TOX21_ERb_BLA_Agonist_ratio
MethyltestosteroneESRRATOX21_PGC_ERR_Antagonist
MethyltestosteroneESRRATOX21_ERR_Antagonist
MethyltestosteroneNR3C1CEETOX_H295R_CORTISOL_dn
MethyltestosteroneNR3C1NVS_NR_hGR
MethyltestosteroneNR3C1CEETOX_H295R_11DCORT_dn
MethyltestosteroneNR3C1TOX21_GR_BLA_Antagonist_ratio
MethyltestosteroneAROT_AR_ARSRC1_0960
MethyltestosteroneAROT_AR_ARSRC1_0480
MethyltestosteroneARACEA_AR_agonist_80hr
MethyltestosteroneARTOX21_AR_LUC_MDAKB2_Agonist_3uM_Nilutamide
MethyltestosteroneARTOX21_AR_BLA_Agonist_ratio
MethyltestosteroneARNVS_NR_hAR
MethyltestosteroneARATG_AR_TRANS_up
MethyltestosteroneARTOX21_AR_LUC_MDAKB2_Agonist
MethyltestosteroneESR1CEETOX_H295R_ESTRONE_dn
MethyltestosteroneESR1CEETOX_H295R_ESTRADIOL_dn
MethyltestosteroneNACEETOX_H295R_ESTRADIOL_dn
MethyltestosteroneNACEETOX_H295R_ESTRONE_dn
MethyltestosteroneSMAD1ATG_BRE_CIS_up
MethyltestosteroneNR3C2CEETOX_H295R_CORTISOL_dn
MethyltestosteroneNR3C2CEETOX_H295R_11DCORT_dn
MethyltestosteroneMMP1BSK_BE3C_MMP1_up
MethyltestosteroneMTF1ATG_MRE_CIS_up
MethyltestosteroneNFE2L2ATG_NRF2_ARE_CIS_up
MethyltestosteroneNFE2L2TOX21_ARE_BLA_agonist_ratio
MethyltestosteroneLEF1ATG_TCF_b_cat_CIS_dn
MethyltestosteronePGRCEETOX_H295R_OHPROG_up
MethyltestosteronePGRCEETOX_H295R_OHPREG_up
MethyltestosteronePGRTOX21_PR_BLA_Antagonist_ratio
MethyltestosteronePGRTOX21_PR_BLA_Agonist_ratio
MethyltestosteronePGRNVS_NR_hPR
MethyltestosteronePLAURBSK_4H_uPAR_down
MethyltestosteronePLAURBSK_3C_uPAR_down
MethyltestosteronePTGER2BSK_LPS_PGE2_up
MethyltestosteroneSREBF1ATG_SREBP_CIS_up
MethyltestosteroneTCF7ATG_TCF_b_cat_CIS_dn
MethyltestosteroneTCF7L2ATG_TCF_b_cat_CIS_dn
MethyltestosteroneTP53ATG_p53_CIS_dn
MethyltestosteroneNR1H2ATG_DR4_LXR_CIS_dn
MethyltestosteroneVDRATG_VDRE_CIS_up
MethyltestosteroneTCF7L1ATG_TCF_b_cat_CIS_dn
MethyltestosteroneNR1I2ATG_PXRE_CIS_up
MethyltestosteroneNR1I2NVS_NR_hPXR
MethyltestosteroneNR1H4TOX21_FXR_BLA_antagonist_ratio
MethyltestosteroneNR1H4OT_FXR_FXRSRC1_1440
MethyltestosteroneNR1H4OT_FXR_FXRSRC1_0480

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