Tetramethrin

Target genes for Tetramethrin is obtained based on ToxCast assay component endpoints.
Chemical nameGene identifierToxCast assay component endpoint name
TetramethrinNR1H3ATG_DR4_LXR_CIS_dn
TetramethrinCREB3ATG_CRE_CIS_up
TetramethrinCEBPBATG_C_EBP_CIS_up
TetramethrinCOL3A1BSK_hDFCGF_CollagenIII_down
TetramethrinCSF1BSK_hDFCGF_MCSF_down
TetramethrinCSF1BSK_LPS_MCSF_down
TetramethrinCYP2B6CLD_CYP2B6_48hr
TetramethrinCYP2B6CLD_CYP2B6_24hr
TetramethrinCYP2B6CLD_CYP2B6_6hr
TetramethrinCYP2C19NVS_ADME_hCYP2C19
TetramethrinCYP2C9NVS_ADME_hCYP2C9
TetramethrinCYP2C18NVS_ADME_hCYP2C18
TetramethrinCYP3A4CLD_CYP3A4_24hr
TetramethrinDRD1NVS_GPCR_hDRD1
TetramethrinEGR1ATG_EGR_CIS_up
TetramethrinSLC29A1NVS_TR_hAdoT
TetramethrinESR1TOX21_ERa_BLA_Antagonist_ratio
TetramethrinESR2TOX21_ERb_BLA_Antagonist_ratio
TetramethrinESRRATOX21_PGC_ERR_Antagonist
TetramethrinESRRATOX21_ERR_Antagonist
TetramethrinF3BSK_3C_TissueFactor_down
TetramethrinFOSATG_AP_1_CIS_up
TetramethrinBACE1NVS_ENZ_hBACE
TetramethrinGLI1ATG_GLI_CIS_up
TetramethrinHIF1AATG_HIF1a_CIS_up
TetramethrinHLA-DRABSK_3C_HLADR_down
TetramethrinHLA-DRABSK_BE3C_HLADR_down
TetramethrinHSF1ATG_HSE_CIS_up
TetramethrinHSF1TOX21_HSE_BLA_agonist_ratio
TetramethrinIL6BSK_CASM3C_IL6_up
TetramethrinCXCL8BSK_SAg_IL8_down
TetramethrinCXCL8BSK_LPS_IL8_down
TetramethrinCXCL10BSK_hDFCGF_IP10_down
TetramethrinAROT_AR_ARSRC1_0960
TetramethrinARACEA_AR_antagonist_80hr
TetramethrinAROT_AR_ARSRC1_0480
TetramethrinARTOX21_AR_BLA_Antagonist_ratio
TetramethrinJUNATG_AP_1_CIS_up
TetramethrinSMAD1ATG_BRE_CIS_up
TetramethrinCXCL9BSK_hDFCGF_MIG_down
TetramethrinCXCL9BSK_SAg_MIG_down
TetramethrinMMP1BSK_BE3C_MMP1_down
TetramethrinMMP9BSK_KF3CT_MMP9_down
TetramethrinMTF1ATG_MRE_CIS_up
TetramethrinMYBATG_Myb_CIS_dn
TetramethrinNFE2L2TOX21_ARE_BLA_agonist_ratio
TetramethrinNFE2L2ATG_NRF2_ARE_CIS_up
TetramethrinNFKB1ATG_NF_kB_CIS_up
TetramethrinSERPINE1BSK_hDFCGF_PAI1_down
TetramethrinPAX6ATG_Pax6_CIS_up
TetramethrinPGRTOX21_PR_BLA_Antagonist_ratio
TetramethrinPLAURBSK_3C_uPAR_down
TetramethrinPLAURBSK_4H_uPAR_down
TetramethrinPOU2F1ATG_Oct_MLP_CIS_up
TetramethrinUGT1A1CLD_UGT1A1_48hr
TetramethrinPPARGATG_PPARg_TRANS_up
TetramethrinPPARGTOX21_PPARg_BLA_antagonist_ratio
TetramethrinPTGER2BSK_LPS_PGE2_down
TetramethrinRORAATG_RORE_CIS_up
TetramethrinRORBATG_RORE_CIS_up
TetramethrinRORCATG_RORE_CIS_up
TetramethrinCCL2BSK_3C_MCP1_down
TetramethrinCCL2BSK_SAg_MCP1_down
TetramethrinCCL2BSK_LPS_MCP1_down
TetramethrinSELEBSK_3C_Eselectin_down
TetramethrinSELEBSK_SAg_Eselectin_down
TetramethrinSELPBSK_4H_Pselectin_down
TetramethrinSLC5A5NIS_RAIU_inhibition
TetramethrinSREBF1ATG_SREBP_CIS_up
TetramethrinTSPONVS_MP_hPBR
TetramethrinTNFBSK_LPS_TNFa_down
TetramethrinTSHRTOX21_TSHR_Agonist_ratio
TetramethrinNR1H2ATG_DR4_LXR_CIS_dn
TetramethrinVCAM1BSK_CASM3C_VCAM1_down
TetramethrinVCAM1BSK_hDFCGF_VCAM1_down
TetramethrinVCAM1BSK_LPS_VCAM1_down
TetramethrinVCAM1BSK_4H_VCAM1_down
TetramethrinVCAM1BSK_3C_VCAM1_down
TetramethrinVDRATG_VDRE_CIS_up
TetramethrinXBP1ATG_Xbp1_CIS_up
TetramethrinCASP3NVS_ENZ_hCASP3
TetramethrinCASP8NVS_ENZ_hCASP8
TetramethrinNR1I2ATG_PXRE_CIS_up
TetramethrinNR1I2ATG_PXR_TRANS_up
TetramethrinCD38BSK_SAg_CD38_down
TetramethrinCD40BSK_SAg_CD40_down
TetramethrinCD40BSK_LPS_CD40_down
TetramethrinCD69BSK_SAg_CD69_down
TetramethrinNR1I3ATG_PBREM_CIS_up
TetramethrinNR1I3NVS_NR_hCAR_Antagonist
TetramethrinNR1I3TOX21_CAR_Agonist
TetramethrinNR1H4OT_FXR_FXRSRC1_0480
TetramethrinNR1H4NVS_NR_hFXR_Antagonist
TetramethrinNR1H4ATG_IR1_CIS_dn

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We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.