Tetramethrin


Literature identifierStudy typeTest dosageEffective dosageEndocrine-mediated endpointsSystems-level perturbations
PMID:16326440IVR5 mg/kg/day 5 mg/kg/dayDecreased uterine weightsReproductive endocrine-mediated perturbations
IVR5 mg/kg/day 5 mg/kg/dayAffects expression of estrogen receptor-beta (ER-beta)Reproductive endocrine-mediated perturbations
IVR5 mg/kg/day 5 mg/kg/dayAffects expression of estrogen receptor-alpha (ER-alpha)Reproductive endocrine-mediated perturbations
IVR100 mg/kg/day 100 mg/kg/dayAffects expression of estrogen receptor-beta (ER-beta)Reproductive endocrine-mediated perturbations
IVR100 mg/kg/day 100 mg/kg/dayDecreased uterine weightsReproductive endocrine-mediated perturbations
IVR100 mg/kg/day 100 mg/kg/dayAffects expression of estrogen receptor-alpha (ER-alpha)Reproductive endocrine-mediated perturbations
IVR200 mg/kg/day 200 mg/kg/dayDecreased uterine weightsReproductive endocrine-mediated perturbations
IVR200 mg/kg/day 200 mg/kg/dayAffects expression of estrogen receptor-alpha (ER-alpha)Reproductive endocrine-mediated perturbations
IVR200 mg/kg/day 200 mg/kg/dayAffects expression of estrogen receptor-beta (ER-beta)Reproductive endocrine-mediated perturbations
IVR10 mg/kg/day 10 mg/kg/dayDecreased uterine weightsReproductive endocrine-mediated perturbations
IVR10 mg/kg/day 10 mg/kg/dayAffects expression of estrogen receptor-beta (ER-beta)Reproductive endocrine-mediated perturbations
IVR10 mg/kg/day 10 mg/kg/dayAffects expression of estrogen receptor-alpha (ER-alpha)Reproductive endocrine-mediated perturbations
IVR10 mg/kg/day 10 mg/kg/dayAffects uterine contractionReproductive endocrine-mediated perturbations
IVR800 mg/kg/day 800 mg/kg/dayAffects expression of estrogen receptor-alpha (ER-alpha)Reproductive endocrine-mediated perturbations
IVR800 mg/kg/day 800 mg/kg/dayDecreased uterine weightsReproductive endocrine-mediated perturbations
IVR800 mg/kg/day 800 mg/kg/dayAffects expression of estrogen receptor-beta (ER-beta)Reproductive endocrine-mediated perturbations
IVR50 mg/kg/day 50 mg/kg/dayDecreased uterine weightsReproductive endocrine-mediated perturbations
IVR50 mg/kg/day 50 mg/kg/dayAffects expression of estrogen receptor-beta (ER-beta)Reproductive endocrine-mediated perturbations
IVR50 mg/kg/day 50 mg/kg/dayAffects expression of estrogen receptor-alpha (ER-alpha)Reproductive endocrine-mediated perturbations

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We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.