Perfluorodecanoic acid

Target genes for Perfluorodecanoic acid is obtained based on ToxCast assay component endpoints.
Chemical nameGene identifierToxCast assay component endpoint name
Perfluorodecanoic acidNR1H3ATG_DR4_LXR_CIS_dn
Perfluorodecanoic acidCCL26BSK_4H_Eotaxin3_down
Perfluorodecanoic acidCREB3ATG_CRE_CIS_up
Perfluorodecanoic acidCOL3A1BSK_hDFCGF_CollagenIII_down
Perfluorodecanoic acidADORA2ANVS_GPCR_hAdoRA2a
Perfluorodecanoic acidCSF1BSK_hDFCGF_MCSF_down
Perfluorodecanoic acidADRA2CNVS_GPCR_hAdra2C
Perfluorodecanoic acidADRB1NVS_GPCR_hAdrb1
Perfluorodecanoic acidCYP2C9NVS_ADME_hCYP2C9
Perfluorodecanoic acidDIO1NHEERL_MED_hDIO1_dn
Perfluorodecanoic acidDRD1NVS_GPCR_hDRD1
Perfluorodecanoic acidDRD4NVS_GPCR_hDRD4.4
Perfluorodecanoic acidDUSP3NVS_ENZ_hDUSP3
Perfluorodecanoic acidEGR1ATG_EGR_CIS_up
Perfluorodecanoic acidESR1ATG_ERa_TRANS_up
Perfluorodecanoic acidESR1TOX21_ERa_BLA_Antagonist_ratio
Perfluorodecanoic acidESR1ATG_ERE_CIS_up
Perfluorodecanoic acidESRRATOX21_ERR_Antagonist
Perfluorodecanoic acidFOSATG_AP_1_CIS_dn
Perfluorodecanoic acidBACE1NVS_ENZ_hBACE
Perfluorodecanoic acidHLA-DRABSK_3C_HLADR_down
Perfluorodecanoic acidHLA-DRABSK_BE3C_HLADR_down
Perfluorodecanoic acidONECUT1ATG_HNF6_CIS_dn
Perfluorodecanoic acidHSF1ATG_HSE_CIS_up
Perfluorodecanoic acidHTR5ANVS_GPCR_h5HT5A
Perfluorodecanoic acidHTR7NVS_GPCR_h5HT7
Perfluorodecanoic acidICAM1BSK_KF3CT_ICAM1_down
Perfluorodecanoic acidIL1ABSK_KF3CT_IL1a_down
Perfluorodecanoic acidIL1ABSK_BE3C_IL1a_down
Perfluorodecanoic acidCXCL8BSK_SAg_IL8_down
Perfluorodecanoic acidCXCL8BSK_hDFCGF_IL8_down
Perfluorodecanoic acidCXCL10BSK_KF3CT_IP10_down
Perfluorodecanoic acidCXCL10BSK_BE3C_IP10_down
Perfluorodecanoic acidCXCL10BSK_hDFCGF_IP10_down
Perfluorodecanoic acidIRF1ATG_ISRE_CIS_dn
Perfluorodecanoic acidARACEA_AR_antagonist_80hr
Perfluorodecanoic acidJUNATG_AP_1_CIS_dn
Perfluorodecanoic acidCXCL9BSK_SAg_MIG_down
Perfluorodecanoic acidCXCL9BSK_hDFCGF_MIG_down
Perfluorodecanoic acidCXCL9BSK_BE3C_MIG_down
Perfluorodecanoic acidMMP1BSK_hDFCGF_MMP1_down
Perfluorodecanoic acidMMP1BSK_BE3C_MMP1_down
Perfluorodecanoic acidMMP3NVS_ENZ_hMMP3
Perfluorodecanoic acidMMP9BSK_KF3CT_MMP9_down
Perfluorodecanoic acidMTF1ATG_MRE_CIS_up
Perfluorodecanoic acidMYCATG_Myc_CIS_up
Perfluorodecanoic acidNFE2L2ATG_NRF2_ARE_CIS_dn
Perfluorodecanoic acidNFE2L2TOX21_ARE_BLA_agonist_ratio
Perfluorodecanoic acidOPRD1NVS_GPCR_hOpiate_D1
Perfluorodecanoic acidOPRM1NVS_GPCR_hOpiate_mu
Perfluorodecanoic acidP2RY1NVS_GPCR_hPY2
Perfluorodecanoic acidSERPINE1BSK_BE3C_PAI1_down
Perfluorodecanoic acidSERPINE1BSK_hDFCGF_PAI1_down
Perfluorodecanoic acidPAX6ATG_Pax6_CIS_up
Perfluorodecanoic acidLEF1ATG_TCF_b_cat_CIS_dn
Perfluorodecanoic acidPGRTOX21_PR_BLA_Antagonist_ratio
Perfluorodecanoic acidPLATBSK_BE3C_tPA_down
Perfluorodecanoic acidPLAUBSK_BE3C_uPA_down
Perfluorodecanoic acidPLAUBSK_KF3CT_uPA_down
Perfluorodecanoic acidPLAURBSK_BE3C_uPAR_down
Perfluorodecanoic acidPOU2F1ATG_Oct_MLP_CIS_up
Perfluorodecanoic acidPPARAATG_PPRE_CIS_up
Perfluorodecanoic acidPPARAATG_PPARa_TRANS_up
Perfluorodecanoic acidPPARDATG_PPRE_CIS_up
Perfluorodecanoic acidPPARGNVS_NR_hPPARg
Perfluorodecanoic acidPPARGATG_PPARg_TRANS_up
Perfluorodecanoic acidPPARGATG_PPRE_CIS_up
Perfluorodecanoic acidPPP1CANVS_ENZ_hPPP1CA
Perfluorodecanoic acidPTPRCNVS_ENZ_hPTPRC
Perfluorodecanoic acidRARGATG_RARg_TRANS_up
Perfluorodecanoic acidRORAATG_RORE_CIS_up
Perfluorodecanoic acidRORBATG_RORE_CIS_up
Perfluorodecanoic acidRORCATG_RORE_CIS_up
Perfluorodecanoic acidRXRBATG_RXRb_TRANS_up
Perfluorodecanoic acidCCL2BSK_KF3CT_MCP1_down
Perfluorodecanoic acidCCL2BSK_3C_MCP1_down
Perfluorodecanoic acidCCL2BSK_SAg_MCP1_down
Perfluorodecanoic acidCCL2BSK_LPS_MCP1_down
Perfluorodecanoic acidSELEBSK_SAg_Eselectin_down
Perfluorodecanoic acidSLC6A2NVS_TR_hNET
Perfluorodecanoic acidSOX1ATG_Sox_CIS_up
Perfluorodecanoic acidTBXA2RNVS_GPCR_hTXA2
Perfluorodecanoic acidTCF7ATG_TCF_b_cat_CIS_dn
Perfluorodecanoic acidTCF7L2ATG_TCF_b_cat_CIS_dn
Perfluorodecanoic acidTFAP2AATG_AP_2_CIS_dn
Perfluorodecanoic acidTFAP2BATG_AP_2_CIS_dn
Perfluorodecanoic acidTGFB1BSK_KF3CT_TGFb1_down
Perfluorodecanoic acidTGFB1BSK_BE3C_TGFb1_down
Perfluorodecanoic acidTGFB1ATG_TGFb_CIS_up
Perfluorodecanoic acidTIMP1BSK_hDFCGF_TIMP1_down
Perfluorodecanoic acidTIMP2BSK_KF3CT_TIMP2_down
Perfluorodecanoic acidTP53APR_HepG2_p53Act_24h_up
Perfluorodecanoic acidTP53APR_HepG2_p53Act_72h_up
Perfluorodecanoic acidTP53ATG_p53_CIS_dn
Perfluorodecanoic acidNR1H2ATG_DR4_LXR_CIS_dn
Perfluorodecanoic acidVCAM1BSK_4H_VCAM1_down
Perfluorodecanoic acidVCAM1BSK_LPS_VCAM1_down
Perfluorodecanoic acidVCAM1BSK_hDFCGF_VCAM1_down
Perfluorodecanoic acidVDRATG_VDRE_CIS_up
Perfluorodecanoic acidXBP1ATG_Xbp1_CIS_up
Perfluorodecanoic acidTCF7L1ATG_TCF_b_cat_CIS_dn
Perfluorodecanoic acidTFAP2DATG_AP_2_CIS_dn
Perfluorodecanoic acidCASP5NVS_ENZ_hCASP5
Perfluorodecanoic acidNR1I2ATG_PXR_TRANS_up
Perfluorodecanoic acidNR1I2ATG_PXRE_CIS_dn
Perfluorodecanoic acidNR1I2NVS_NR_hPXR
Perfluorodecanoic acidCD38BSK_SAg_CD38_down
Perfluorodecanoic acidCD40BSK_SAg_CD40_down
Perfluorodecanoic acidCD69BSK_SAg_CD69_down
Perfluorodecanoic acidNR1I3ATG_PBREM_CIS_up
Perfluorodecanoic acidNR1H4NVS_NR_hFXR_Agonist
Perfluorodecanoic acidNR1H4ATG_FXR_TRANS_up

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We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.