Bisphenol A diglycidyl ether


Curated chemical-phenotype interactions from CTD
GO IDGO nameInteraction typeReference
GO:0000085 Mitotic g2 phase Affects phenotype PMID:36181250
GO:0001541 Ovarian follicle development Affects phenotype PMID:36464114
GO:0002523 Leukocyte migration involved in inflammatory response Increases phenotype PMID:30343038; PMID:36249784
GO:0002534 Cytokine production involved in inflammatory response Increases phenotype PMID:24612634
GO:0002540 Leukotriene production involved in inflammatory response Increases phenotype PMID:24612634
GO:0004111 Creatine kinase activity Increases phenotype PMID:32737941
GO:0006006 Glucose metabolic process Affects phenotype PMID:37659742
GO:0006304 Dna modification Increases phenotype PMID:36464114; PMID:37450014
GO:0006602 Creatinine catabolic process Decreases phenotype PMID:27363640; PMID:32742113
GO:0006641 Triglyceride metabolic process Affects phenotype PMID:37659742
GO:0006693 Prostaglandin metabolic process Affects phenotype PMID:36875279
GO:0006695 Cholesterol biosynthetic process Increases phenotype PMID:25169908; PMID:30343038
GO:0006749 Glutathione metabolic process Affects phenotype PMID:32627286; PMID:34409680; PMID:36249784; PMID:36249937
GO:0006809 Nitric oxide biosynthetic process Increases phenotype PMID:30343038
GO:0006874 Cellular calcium ion homeostasis Affects phenotype PMID:32508751
GO:0006909 Phagocytosis Decreases phenotype PMID:24612634
GO:0006915 Apoptotic process Increases phenotype PMID:11879183; PMID:11879183; PMID:21296151; PMID:12824901; PMID:15383218; PMID:16806087; PMID:32737941; PMID:36181250; PMID:37450014
GO:0007128 Meiotic prophase i Affects phenotype PMID:36464114
GO:0007286 Spermatid development Decreases phenotype PMID:29953732
GO:0007420 Brain development Affects phenotype PMID:32142877
GO:0007613 Memory Decreases phenotype PMID:32627286
GO:0007623 Circadian rhythm Affects phenotype PMID:36181250
GO:0008283 Cell population proliferation Increases phenotype PMID:25874449
GO:0008380 Rna splicing Affects phenotype PMID:36464114
GO:0010942 Positive regulation of cell death Increases phenotype PMID:29953732
GO:0016042 Lipid catabolic process Affects phenotype PMID:32627286; PMID:34409680
GO:0019627 Urea metabolic process Affects phenotype PMID:32737941; PMID:34409680
GO:0019628 Urate catabolic process Decreases phenotype PMID:32742113
GO:0019674 Nad metabolic process Affects phenotype PMID:36875279
GO:0022008 Neurogenesis Decreases phenotype PMID:32142877
GO:0030199 Collagen fibril organization Increases phenotype PMID:30343038
GO:0030282 Bone mineralization Decreases phenotype PMID:31709877
GO:0032776 Dna methylation on cytosine Affects phenotype PMID:36464114
GO:0032930 Positive regulation of superoxide anion generation Increases phenotype PMID:27363640; PMID:32742113
GO:0033993 Response to lipid Decreases phenotype PMID:29305999
GO:0034440 Lipid oxidation Increases phenotype PMID:27363640; PMID:36249937; PMID:37450014
GO:0035815 Positive regulation of renal sodium excretion Increases phenotype PMID:27363640
GO:0036343 Psychomotor behavior Decreases phenotype PMID:32627286
GO:0042310 Vasoconstriction Increases phenotype PMID:25169908
GO:0042554 Superoxide anion generation Affects phenotype PMID:34409680
GO:0042756 Drinking behavior Decreases phenotype PMID:34553211
GO:0044237 Cellular metabolic process Decreases phenotype PMID:36181250; PMID:36875279
GO:0045023 G0 to g1 transition Affects phenotype PMID:36875279
GO:0045453 Bone resorption Affects phenotype PMID:37659742
GO:0046209 Nitric oxide metabolic process Affects phenotype PMID:36249937
GO:0046323 Glucose import Affects phenotype PMID:36875279
GO:0046415 Urate metabolic process Decreases phenotype PMID:27363640
GO:0046449 Creatinine metabolic process Affects phenotype PMID:32737941; PMID:34409680; PMID:36249937
GO:0048149 Behavioral response to ethanol Decreases phenotype PMID:34553211
GO:0048477 Oogenesis Affects phenotype PMID:36464114
GO:0048487 Beta-tubulin binding Decreases phenotype PMID:36181250
GO:0050890 Cognition Affects phenotype PMID:36249784
GO:0050996 Positive regulation of lipid catabolic process Increases phenotype PMID:32742113
GO:0051309 Female meiosis chromosome separation Affects phenotype PMID:36464114
GO:0051321 Meiotic cell cycle Affects phenotype PMID:36464114
GO:0051332 Meiotic s phase Affects phenotype PMID:36464114
GO:0051881 Regulation of mitochondrial membrane potential Affects phenotype PMID:11879183
GO:0055072 Iron ion homeostasis Affects phenotype PMID:32737941
GO:0055075 Potassium ion homeostasis Decreases phenotype PMID:27363640; PMID:32737941
GO:0060612 Adipose tissue development Affects phenotype PMID:31709877; PMID:37659742
GO:0061370 Testosterone biosynthetic process Decreases phenotype PMID:28482050; PMID:37450014
GO:0070341 Fat cell proliferation Affects phenotype PMID:37659742
GO:0070343 White fat cell proliferation Increases phenotype PMID:30343038
GO:0070994 Detection of oxidative stress Increases phenotype PMID:25940660; PMID:32737941; PMID:34409680; PMID:36249784
GO:0072593 Reactive oxygen species metabolic process Affects phenotype PMID:32627286
GO:0097251 Leukotriene b4 biosynthetic process Increases phenotype PMID:24188201
GO:1900745 Positive regulation of p38mapk cascade Increases phenotype PMID:27274199
GO:1901216 Positive regulation of neuron death Increases phenotype PMID:27274199
GO:1901318 Negative regulation of flagellated sperm motility Increases phenotype PMID:29953732
GO:1901713 Negative regulation of urea catabolic process Increases phenotype PMID:32742113
GO:1903046 Meiotic cell cycle process Affects phenotype PMID:36464114
GO:1903047 Mitotic cell cycle process Affects phenotype PMID:36181250; PMID:36875279
GO:1903787 Negative regulation of glutathione biosynthetic process Increases phenotype PMID:32742113
GO:1903979 Negative regulation of microglial cell activation Increases phenotype PMID:29162556
GO:1904643 Response to curcumin Decreases phenotype PMID:29480285
GO:1905836 Response to triterpenoid Decreases phenotype PMID:27274199
GO:1990138 Neuron projection extension Increases phenotype PMID:32142877
GO:2000255 Negative regulation of male germ cell proliferation Increases phenotype PMID:29953732
GO:2001024 Negative regulation of response to drug Increases phenotype PMID:30229846
GO:2001025 Positive regulation of response to drug Decreases phenotype PMID:27363640
DISCLAIMER

We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.