Diisodecyl phthalate


Curated chemical-phenotype interactions from CTD
GO IDGO nameInteraction typeReference
GO:0001556 Oocyte maturation Decreases phenotype PMID:26545148
GO:0002523 Leukocyte migration involved in inflammatory response Increases phenotype PMID:27871981
GO:0002524 Hypersensitivity Increases phenotype PMID:27871981
GO:0006750 Glutathione biosynthetic process Decreases phenotype PMID:27871981
GO:0007283 Spermatogenesis Decreases phenotype PMID:32387388; PMID:37364641
GO:0008285 Negative regulation of cell population proliferation Increases phenotype PMID:35739755
GO:0009566 Fertilization Decreases phenotype PMID:26545148
GO:0010884 Positive regulation of lipid storage Increases phenotype PMID:29410257
GO:0010906 Regulation of glucose metabolic process Affects phenotype PMID:35739755; PMID:37364641
GO:0035176 Social behavior Decreases phenotype PMID:32518293
GO:0036269 Swimming behavior Affects phenotype PMID:32518293
GO:0042632 Cholesterol homeostasis Decreases phenotype PMID:35739755
GO:0043065 Positive regulation of apoptotic process Increases phenotype PMID:35739755; PMID:37364641
GO:0043303 Mast cell degranulation Increases phenotype PMID:27871981
GO:0046622 Positive regulation of organ growth Increases phenotype PMID:32518293
GO:0046881 Positive regulation of follicle-stimulating hormone secretion Increases phenotype PMID:37364641
GO:0061370 Testosterone biosynthetic process Affects phenotype PMID:32387388
GO:0070328 Triglyceride homeostasis Decreases phenotype PMID:35739755
GO:0072520 Seminiferous tubule development Affects phenotype PMID:37364641
GO:0090326 Positive regulation of locomotion involved in locomotory behavior Increases phenotype PMID:32518293
GO:0098743 Cell aggregation Increases phenotype PMID:32387388
GO:0140354 Lipid import into cell Increases phenotype PMID:35739755
GO:1902884 Positive regulation of response to oxidative stress Increases phenotype PMID:35739755
GO:1903409 Reactive oxygen species biosynthetic process Increases phenotype PMID:27871981
GO:1904598 Positive regulation of connective tissue replacement involved in inflammatory response wound healing Increases phenotype PMID:35739755
GO:2000845 Positive regulation of testosterone secretion Increases phenotype PMID:37364641
GO:2000866 Positive regulation of estradiol secretion Increases phenotype PMID:37364641
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We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.