| GO ID | GO name | Interaction type | Reference |
|---|---|---|---|
| GO:0000737 | Dna catabolic process, endonucleolytic | Increases phenotype | PMID:34503147; PMID:34830855 |
| GO:0001556 | Oocyte maturation | Increases phenotype | PMID:30266436 |
| GO:0002523 | Leukocyte migration involved in inflammatory response | Increases phenotype | PMID:34060014 |
| GO:0003993 | Acid phosphatase activity | Decreases phenotype | PMID:33226166 |
| GO:0004784 | Superoxide dismutase activity | Decreases phenotype | PMID:33245377 |
| GO:0006117 | Acetaldehyde metabolic process | Affects phenotype | PMID:34830855 |
| GO:0006641 | Triglyceride metabolic process | Affects phenotype | PMID:32810590 |
| GO:0006749 | Glutathione metabolic process | Affects phenotype | PMID:33245377; PMID:33586219 |
| GO:0006954 | Inflammatory response | Increases phenotype | PMID:33586219 |
| GO:0007284 | Spermatogonial cell division | Decreases phenotype | PMID:28576679 |
| GO:0007285 | Primary spermatocyte growth | Decreases phenotype | PMID:28576679 |
| GO:0007286 | Spermatid development | Decreases phenotype | PMID:28576679 |
| GO:0008283 | Cell population proliferation | Affects phenotype | PMID:33226166; PMID:34503147; PMID:34830855 |
| GO:0016042 | Lipid catabolic process | Affects phenotype | PMID:33586219 |
| GO:0030185 | Nitric oxide transport | Affects phenotype | PMID:33226166 |
| GO:0030263 | Apoptotic chromosome condensation | Increases phenotype | PMID:33586219 |
| GO:0031393 | Negative regulation of prostaglandin biosynthetic process | Increases phenotype | PMID:26359731 |
| GO:0032125 | Micronucleus organization | Increases phenotype | PMID:33245377 |
| GO:0034109 | Homotypic cell-cell adhesion | Increases phenotype | PMID:34503147 |
| GO:0036164 | Cell-abiotic substrate adhesion | Decreases phenotype | PMID:34503147 |
| GO:0044237 | Cellular metabolic process | Decreases phenotype | PMID:33245377 |
| GO:0045333 | Cellular respiration | Increases phenotype | PMID:34503147 |
| GO:0046034 | Atp metabolic process | Affects phenotype | PMID:34503147 |
| GO:0048137 | Spermatocyte division | Decreases phenotype | PMID:28576679 |
| GO:0048870 | Cell motility | Increases phenotype | PMID:34503147 |
| GO:0060011 | Sertoli cell proliferation | Increases phenotype | PMID:28576679 |
| GO:0060179 | Male mating behavior | Affects phenotype | PMID:34060014 |
| GO:0061370 | Testosterone biosynthetic process | Affects phenotype | PMID:34060014 |
| GO:0070994 | Detection of oxidative stress | Increases phenotype | PMID:34060014 |
| GO:0090398 | Cellular senescence | Increases phenotype | PMID:34830855 |
| GO:0097722 | Sperm motility | Decreases phenotype | PMID:33586219; PMID:34060014 |
| GO:2000255 | Negative regulation of male germ cell proliferation | Increases phenotype | PMID:28576679 |
We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.