| GO ID | GO name | Interaction type | Reference |
|---|---|---|---|
| GO:0000045 | Autophagosome assembly | Increases phenotype | PMID:20594614; PMID:31648047 |
| GO:0000084 | Mitotic s phase | Affects phenotype | PMID:37394047 |
| GO:0000104 | Succinate dehydrogenase activity | Decreases phenotype | PMID:31820278 |
| GO:0000165 | Mapk cascade | Increases phenotype | PMID:18242171 |
| GO:0000266 | Mitochondrial fission | Decreases phenotype | PMID:26770656 |
| GO:0000278 | Mitotic cell cycle | Decreases phenotype | PMID:17697112; PMID:21223980 |
| GO:0000422 | Autophagy of mitochondrion | Increases phenotype | PMID:24036476; PMID:26028482 |
| GO:0000423 | Mitophagy | Increases phenotype | PMID:36538285; PMID:37156403 |
| GO:0000737 | Dna catabolic process, endonucleolytic | Increases phenotype | PMID:28703385; PMID:34042043 |
| GO:0001216 | Dna-binding transcription activator activity | Decreases phenotype | PMID:35919817 |
| GO:0001755 | Neural crest cell migration | Decreases phenotype | PMID:26238599 |
| GO:0001774 | Microglial cell activation | Increases phenotype | PMID:27316720; PMID:27316720; PMID:30222980; PMID:36706892; PMID:29649621; PMID:30222980; PMID:30408497; PMID:32088201; PMID:34391968; PMID:36706892; PMID:36965781; PMID:38960072 |
| GO:0001776 | Leukocyte homeostasis | Affects phenotype | PMID:36965781 |
| GO:0001780 | Neutrophil homeostasis | Affects phenotype | PMID:28903492 |
| GO:0001836 | Release of cytochrome c from mitochondria | Increases phenotype | PMID:21216964; PMID:21778691; PMID:21778691; PMID:29183837; PMID:29183837 |
| GO:0001895 | Retina homeostasis | Decreases phenotype | PMID:31969611 |
| GO:0001932 | Regulation of protein phosphorylation | Affects phenotype | PMID:32860006 |
| GO:0001958 | Endochondral ossification | Decreases phenotype | PMID:28374803 |
| GO:0002157 | Positive regulation of thyroid hormone mediated signaling pathway | Increases phenotype | PMID:30818834 |
| GO:0002260 | Lymphocyte homeostasis | Affects phenotype | PMID:28903492; PMID:36965781 |
| GO:0002420 | Natural killer cell mediated cytotoxicity directed against tumor cell target | Decreases phenotype | PMID:17149696 |
| GO:0002693 | Positive regulation of cellular extravasation | Increases phenotype | PMID:32937126 |
| GO:0002762 | Negative regulation of myeloid leukocyte differentiation | Increases phenotype | PMID:28374803 |
| GO:0003422 | Growth plate cartilage morphogenesis | Decreases phenotype | PMID:28374803 |
| GO:0004069 | L-aspartate:2-oxoglutarate aminotransferase activity | Increases phenotype | PMID:35253580 |
| GO:0004129 | Cytochrome-c oxidase activity | Decreases phenotype | PMID:36774383 |
| GO:0004364 | Glutathione transferase activity | Decreases phenotype | PMID:28389404 |
| GO:0004392 | Heme oxygenase (decyclizing) activity | Increases phenotype | PMID:32033040 |
| GO:0004457 | Lactate dehydrogenase activity | Increases phenotype | PMID:31820278; PMID:32360863; PMID:34021431; PMID:34042043; PMID:34182063; PMID:35187747 |
| GO:0004602 | Glutathione peroxidase activity | Decreases phenotype | PMID:26446018; PMID:27016191; PMID:27016191; PMID:28238857; PMID:28389404; PMID:35187747; PMID:28238857; PMID:28389404; PMID:35187747; PMID:35253580 |
| GO:0004679 | Amp-activated protein kinase activity | Increases phenotype | PMID:27629431; PMID:33137417 |
| GO:0004784 | Superoxide dismutase activity | Increases phenotype | PMID:23357119; PMID:23963993; PMID:24755484; PMID:24755484; PMID:27053302; PMID:29886133; PMID:25446015; PMID:25725130; PMID:27053302; PMID:27316720; PMID:27316720; PMID:30001633; PMID:28238857; PMID:28238857; PMID:28389404; PMID:30222980; PMID:35187747; PMID:36706892; PMID:36965781; PMID:28389404; PMID:29520721; PMID:29886133; PMID:30001633; PMID:30222980; PMID:31714633; PMID:31820278; PMID:34042043; PMID:35187747; PMID:35253580; PMID:36706892; PMID:36774383; PMID:36965781 |
| GO:0004791 | Thioredoxin-disulfide reductase activity | Decreases phenotype | PMID:27252111 |
| GO:0005388 | P-type calcium transporter activity | Decreases phenotype | PMID:28389404 |
| GO:0005391 | P-type sodium:potassium-exchanging transporter activity | Decreases phenotype | PMID:28389404; PMID:28389404; PMID:35187747; PMID:35187747 |
| GO:0005977 | Glycogen metabolic process | Increases phenotype | PMID:28374803 |
| GO:0006072 | Glycerol-3-phosphate metabolic process | Increases phenotype | PMID:31974165 |
| GO:0006089 | Lactate metabolic process | Affects phenotype | PMID:32006662; PMID:39922521 |
| GO:0006096 | Glycolytic process | Increases phenotype | PMID:21736921; PMID:26358042; PMID:31654802; PMID:32607615; PMID:7595576 |
| GO:0006099 | Tricarboxylic acid cycle | Decreases phenotype | PMID:31974165 |
| GO:0006116 | Nadh oxidation | Decreases phenotype | PMID:29095437 |
| GO:0006119 | Oxidative phosphorylation | Decreases phenotype | PMID:31654802; PMID:35337893 |
| GO:0006120 | Mitochondrial electron transport, nadh to ubiquinone | Decreases phenotype | PMID:26207612; PMID:26358042; PMID:27535828 |
| GO:0006121 | Mitochondrial electron transport, succinate to ubiquinone | Decreases phenotype | PMID:32937126 |
| GO:0006123 | Mitochondrial electron transport, cytochrome c to oxygen | Decreases phenotype | PMID:27535828 |
| GO:0006264 | Mitochondrial dna replication | Decreases phenotype | PMID:24374061; PMID:33515431 |
| GO:0006304 | Dna modification | Increases phenotype | PMID:29438559; PMID:36400285; PMID:36446982 |
| GO:0006306 | Dna methylation | Increases phenotype | PMID:35919817 |
| GO:0006309 | Apoptotic dna fragmentation | Increases phenotype | PMID:11097871; PMID:12496265; PMID:15120578; PMID:15280438; PMID:16402917; PMID:19777565 |
| GO:0006497 | Protein lipidation | Affects phenotype | PMID:32001317; PMID:35104487 |
| GO:0006537 | Glutamate biosynthetic process | Decreases phenotype | PMID:28238857 |
| GO:0006538 | Glutamate catabolic process | Decreases phenotype | PMID:35337893 |
| GO:0006543 | Glutamine catabolic process | Increases phenotype | PMID:25800467 |
| GO:0006606 | Protein import into nucleus | Affects phenotype | PMID:32088201 |
| GO:0006626 | Protein targeting to mitochondrion | Affects phenotype | PMID:32001317; PMID:32088201 |
| GO:0006741 | Nadp biosynthetic process | Affects phenotype | PMID:31654802 |
| GO:0006749 | Glutathione metabolic process | Increases phenotype | PMID:25843018; PMID:26276080; PMID:27108097; PMID:27316720; PMID:27316720; PMID:30001633; PMID:27535828; PMID:29665408; PMID:30001633; PMID:30141137; PMID:30141137; PMID:31408661; PMID:30472438; PMID:31251943; PMID:31820278; PMID:34021431; PMID:35187747; PMID:35187747; PMID:36706892; PMID:36965781; PMID:36706892; PMID:36965781 |
| GO:0006750 | Glutathione biosynthetic process | Decreases phenotype | PMID:23357119; PMID:23963993; PMID:24755484; PMID:24755484; PMID:27053302; PMID:28245986; PMID:25446015; PMID:25481089; PMID:25725130; PMID:26446018; PMID:27053302; PMID:28238857; PMID:28238857; PMID:30222980; PMID:28245986; PMID:28389404; PMID:30222980; PMID:31714633 |
| GO:0006754 | Atp biosynthetic process | Increases phenotype | PMID:17149696; PMID:19923925; PMID:23530063; PMID:25725130; PMID:26770656; PMID:29955902; PMID:30857887; PMID:32001317 |
| GO:0006809 | Nitric oxide biosynthetic process | Increases phenotype | PMID:22928487; PMID:28389404 |
| GO:0006811 | Monoatomic ion transport | Affects phenotype | PMID:19442964 |
| GO:0006879 | Cellular iron ion homeostasis | Affects phenotype | PMID:34391968 |
| GO:0006914 | Autophagy | Increases phenotype | PMID:19628769; PMID:21216964; PMID:24374061; PMID:25725130; PMID:26847702; PMID:37979659 |
| GO:0006915 | Apoptotic process | Affects phenotype | PMID:11097871; PMID:11121805; PMID:12177198; PMID:12496265; PMID:14622122; PMID:14976342; PMID:14976342; PMID:15280438; PMID:17324951; PMID:15120578; PMID:15120578; PMID:18201823; PMID:15280438; PMID:15659109; PMID:15659109; PMID:21736921; PMID:26770656; PMID:27180985; PMID:7931358; PMID:16402917; PMID:16402917; PMID:23189969; PMID:17324951; PMID:18201823; PMID:18242171; PMID:18242171; PMID:20546814; PMID:20594614; PMID:21778691; PMID:23189969; PMID:23593279; PMID:24755484; PMID:27053302; PMID:29886133; PMID:32001317; PMID:34182063; PMID:34602532; PMID:18538940; PMID:19442964; PMID:19777565; PMID:19777565; PMID:26028482; PMID:19857556; PMID:20546814; PMID:20594614; PMID:21216964; PMID:21736921; PMID:21778691; PMID:23189969; PMID:23357119; PMID:23593279; PMID:23807224; PMID:24290359; PMID:24732427; PMID:24755484; PMID:24830863; PMID:25496994; PMID:25725130; PMID:26028482; PMID:26770656; PMID:27053302; PMID:27180985; PMID:29174113; PMID:29886133; PMID:31585160; PMID:32001317; PMID:34182063; PMID:34602532; PMID:34808100; PMID:36538285; PMID:37394047; PMID:8891335 |
| GO:0006954 | Inflammatory response | Increases phenotype | PMID:32088201; PMID:36538285 |
| GO:0006974 | Cellular response to dna damage stimulus | Increases phenotype | PMID:19591892; PMID:21778691; PMID:21778691; PMID:28245986; PMID:23816754; PMID:25136123; PMID:25481089; PMID:31820278; PMID:27252111; PMID:28245986; PMID:28286206; PMID:31820278 |
| GO:0006979 | Response to oxidative stress | Increases phenotype | PMID:11097871; PMID:12177198; PMID:12496265; PMID:15120578; PMID:15659109; PMID:15659109; PMID:18579341; PMID:15904944; PMID:16115015; PMID:16402917; PMID:16580092; PMID:18579341; PMID:19777565; PMID:21223980 |
| GO:0006997 | Nucleus organization | Affects phenotype | PMID:26446018 |
| GO:0007005 | Mitochondrion organization | Decreases phenotype | PMID:20594614; PMID:20594614; PMID:24374061; PMID:24792327; PMID:30240821; PMID:24792327; PMID:25682864; PMID:26739068; PMID:26770656; PMID:30240821; PMID:32088201; PMID:32392329 |
| GO:0007049 | Cell cycle | Decreases phenotype | PMID:21223980 |
| GO:0007204 | Positive regulation of cytosolic calcium ion concentration | Increases phenotype | PMID:26276080; PMID:28774849 |
| GO:0007224 | Smoothened signaling pathway | Decreases phenotype | PMID:31652400 |
| GO:0007565 | Female pregnancy | Decreases phenotype | PMID:32937126 |
| GO:0007601 | Visual perception | Decreases phenotype | PMID:35163535 |
| GO:0007610 | Behavior | Affects phenotype | PMID:33823232 |
| GO:0007612 | Learning | Decreases phenotype | PMID:28238857; PMID:28238857; PMID:36965781; PMID:33402167; PMID:36965781 |
| GO:0007613 | Memory | Decreases phenotype | PMID:28238857; PMID:28238857; PMID:29520721; PMID:29520721; PMID:33402167; PMID:36048341; PMID:35822592; PMID:36048341; PMID:36965781 |
| GO:0007625 | Grooming behavior | Affects phenotype | PMID:35654124; PMID:35654124; PMID:36538285; PMID:36538285 |
| GO:0007626 | Locomotory behavior | Affects phenotype | PMID:25130663 |
| GO:0007628 | Adult walking behavior | Affects phenotype | PMID:30001633; PMID:36774383 |
| GO:0008053 | Mitochondrial fusion | Decreases phenotype | PMID:26770656 |
| GO:0008137 | Nadh dehydrogenase (ubiquinone) activity | Decreases phenotype | PMID:18022205; PMID:20100866; PMID:20423107; PMID:23357119; PMID:25770932; PMID:25770932; PMID:26739068; PMID:26739068; PMID:28389404; PMID:29174113; PMID:29520721; PMID:29955902; PMID:32001317; PMID:34634269; PMID:35187747; PMID:36774383 |
| GO:0008177 | Succinate dehydrogenase (ubiquinone) activity | Decreases phenotype | PMID:34042043 |
| GO:0008219 | Cell death | Increases phenotype | PMID:10486581; PMID:11527970; PMID:10967318; PMID:11527970; PMID:15910763; PMID:16115015; PMID:16115015; PMID:19135049; PMID:27045591; PMID:16580092; PMID:17123556; PMID:19135049; PMID:19633536; PMID:19923925; PMID:21216964; PMID:21216964; PMID:27133439; PMID:21219333; PMID:21223980; PMID:21223980; PMID:23189969; PMID:21736921; PMID:30001633; PMID:21778691; PMID:22041943; PMID:22906069; PMID:23868305; PMID:24374061; PMID:24451142; PMID:28359145; PMID:21778691; PMID:24451142; PMID:22041943; PMID:22289031; PMID:22319455; PMID:22560901; PMID:22906069; PMID:23189969; PMID:23816754; PMID:23868305; PMID:23882024; PMID:24374061; PMID:24451142; PMID:25106480; PMID:25106480; PMID:25263579; PMID:27133439; PMID:25130663; PMID:29428530; PMID:25263579; PMID:25446015; PMID:26847702; PMID:27045591; PMID:27133439; PMID:28359145; PMID:28389404; PMID:28526446; PMID:28526446; PMID:30222980; PMID:28526446; PMID:35104487; PMID:30001633; PMID:30222980; PMID:32607615; PMID:35104487; PMID:35163535; PMID:36400285 |
| GO:0008283 | Cell population proliferation | Increases phenotype | PMID:17697112; PMID:18579341; PMID:18579341; PMID:24002177; PMID:24638036; PMID:26770656; PMID:27045591; PMID:28245986; PMID:20100866; PMID:21223980; PMID:21223980; PMID:26739068; PMID:22560901; PMID:22872702; PMID:23128054; PMID:23441691; PMID:23807224; PMID:23963993; PMID:34642769; PMID:24002177; PMID:24304935; PMID:24304935; PMID:24631677; PMID:24755484; PMID:28245986; PMID:24638036; PMID:24755484; PMID:25725130; PMID:26739068; PMID:26770656; PMID:26963176; PMID:27045591; PMID:28245986; PMID:30857887 |
| GO:0008285 | Negative regulation of cell population proliferation | Increases phenotype | PMID:29458170; PMID:29665408; PMID:30141137; PMID:30141137; PMID:31342299; PMID:31408661; PMID:31926197; PMID:32368861; PMID:30207190; PMID:30472438; PMID:30673822; PMID:30686998; PMID:30927257; PMID:31251943; PMID:31342299; PMID:31926197; PMID:32368861; PMID:32522578; PMID:32949729; PMID:33137417; PMID:37210002; PMID:39551124 |
| GO:0008360 | Regulation of cell shape | Affects phenotype | PMID:30673822 |
| GO:0008361 | Regulation of cell size | Affects phenotype | PMID:37394047 |
| GO:0008566 | Mitochondrial protein-transporting atpase activity | Decreases phenotype | PMID:36774383 |
| GO:0009060 | Aerobic respiration | Decreases phenotype | PMID:24295472; PMID:25827955; PMID:26108578; PMID:26141520; PMID:26187750; PMID:26358042; PMID:29991444; PMID:31251943; PMID:31926197 |
| GO:0009416 | Response to light stimulus | Decreases phenotype | PMID:31969611 |
| GO:0010243 | Response to organonitrogen compound | Decreases phenotype | PMID:29458170 |
| GO:0010424 | Dna methylation on cytosine within a cg sequence | Affects phenotype | PMID:32178731; PMID:32937126 |
| GO:0010507 | Negative regulation of autophagy | Increases phenotype | PMID:33137417; PMID:37224993 |
| GO:0010729 | Positive regulation of hydrogen peroxide biosynthetic process | Increases phenotype | PMID:27535828 |
| GO:0010800 | Positive regulation of peptidyl-threonine phosphorylation | Increases phenotype | PMID:27629431 |
| GO:0010917 | Negative regulation of mitochondrial membrane potential | Increases phenotype | PMID:23454145; PMID:25163676; PMID:29371327; PMID:29371327; PMID:31408661; PMID:30673822; PMID:31926197; PMID:35505273; PMID:35728354 |
| GO:0010918 | Positive regulation of mitochondrial membrane potential | Decreases phenotype | PMID:25428620; PMID:25693864; PMID:26086368; PMID:26276080; PMID:26276080; PMID:30141137; PMID:26358042; PMID:27108097; PMID:27510327; PMID:27554043; PMID:28348719; PMID:30141137; PMID:30472438 |
| GO:0010940 | Positive regulation of necrotic cell death | Increases phenotype | PMID:27535828; PMID:31022188; PMID:35833337 |
| GO:0010942 | Positive regulation of cell death | Increases phenotype | PMID:23593274; PMID:25693864; PMID:26031332; PMID:26086368; PMID:26124276; PMID:26409479; PMID:26276080; PMID:27510327; PMID:29665408; PMID:30472438; PMID:30686998; PMID:9282833 |
| GO:0010972 | Negative regulation of g2/m transition of mitotic cell cycle | Increases phenotype | PMID:32368861 |
| GO:0010975 | Regulation of neuron projection development | Affects phenotype | PMID:32913905 |
| GO:0010977 | Negative regulation of neuron projection development | Increases phenotype | PMID:28962525 |
| GO:0015986 | Proton motive force-driven atp synthesis | Increases phenotype | PMID:7251582 |
| GO:0016042 | Lipid catabolic process | Increases phenotype | PMID:23963993; PMID:27252111; PMID:27316720; PMID:27316720; PMID:30001633; PMID:28238857; PMID:28238857; PMID:30222980; PMID:28245986; PMID:28245986; PMID:30951809; PMID:28389404; PMID:29520721; PMID:29520721; PMID:33279658; PMID:29886133; PMID:30001633; PMID:30222980; PMID:31714633; PMID:31820278; PMID:32092105; PMID:33279658; PMID:33823232; PMID:35919817 |
| GO:0016049 | Cell growth | Increases phenotype | PMID:27345029; PMID:27345029; PMID:28359145; PMID:29183837; PMID:28359145; PMID:29134401; PMID:29174113; PMID:29183837; PMID:29331484; PMID:29428530; PMID:29955902 |
| GO:0016174 | Nad(p)h oxidase h2o2-forming activity | Increases phenotype | PMID:25446015 |
| GO:0016505 | Peptidase activator activity involved in apoptotic process | Increases phenotype | PMID:31022188 |
| GO:0016567 | Protein ubiquitination | Increases phenotype | PMID:27345029 |
| GO:0016887 | Atp hydrolysis activity | Decreases phenotype | PMID:35253580 |
| GO:0017014 | Protein nitrosylation | Affects phenotype | PMID:29649621 |
| GO:0018158 | Protein oxidation | Increases phenotype | PMID:20594614; PMID:27016191; PMID:27016191; PMID:35187747; PMID:27345029; PMID:27535828; PMID:27535828; PMID:30472438; PMID:30472438; PMID:30951809; PMID:31969611; PMID:32115830; PMID:33823232; PMID:35187747 |
| GO:0019244 | Lactate biosynthetic process from pyruvate | Increases phenotype | PMID:31974165 |
| GO:0019249 | Lactate biosynthetic process | Increases phenotype | PMID:20100866; PMID:35919817 |
| GO:0019646 | Aerobic electron transport chain | Decreases phenotype | PMID:29910772 |
| GO:0019722 | Calcium-mediated signaling | Increases phenotype | PMID:11164812 |
| GO:0022832 | Voltage-gated channel activity | Affects phenotype | PMID:33512997 |
| GO:0022900 | Electron transport chain | Decreases phenotype | PMID:2609 |
| GO:0022904 | Respiratory electron transport chain | Decreases phenotype | PMID:25237061; PMID:28013001 |
| GO:0023061 | Signal release | Increases phenotype | PMID:29458170 |
| GO:0030262 | Apoptotic nuclear changes | Increases phenotype | PMID:26124276 |
| GO:0030263 | Apoptotic chromosome condensation | Increases phenotype | PMID:27510327; PMID:36706892; PMID:38960072 |
| GO:0030308 | Negative regulation of cell growth | Increases phenotype | PMID:37210002 |
| GO:0030432 | Peristalsis | Decreases phenotype | PMID:36965781 |
| GO:0031103 | Axon regeneration | Affects phenotype | PMID:35163535 |
| GO:0031117 | Positive regulation of microtubule depolymerization | Increases phenotype | PMID:27108097 |
| GO:0031175 | Neuron projection development | Decreases phenotype | PMID:33512557; PMID:35822592 |
| GO:0031323 | Regulation of cellular metabolic process | Affects phenotype | PMID:28774849 |
| GO:0031324 | Negative regulation of cellular metabolic process | Increases phenotype | PMID:28774849; PMID:32937854 |
| GO:0031394 | Positive regulation of prostaglandin biosynthetic process | Increases phenotype | PMID:28110601 |
| GO:0031941 | Filamentous actin | Increases phenotype | PMID:30769001 |
| GO:0031987 | Locomotion involved in locomotory behavior | Decreases phenotype | PMID:22041943; PMID:23357119; PMID:27585560; PMID:28585189; PMID:28585189; PMID:29520721; PMID:30222980; PMID:33279658; PMID:34182063; PMID:35104487; PMID:36706892; PMID:36965781; PMID:29520721; PMID:30001633; PMID:30001633; PMID:32088201; PMID:36538285; PMID:30222980; PMID:32088201; PMID:33279658; PMID:34182063; PMID:35104487; PMID:35589691; PMID:35822592; PMID:36538285; PMID:36706892; PMID:36965781 |
| GO:0032125 | Micronucleus organization | Increases phenotype | PMID:32305330; PMID:37394047 |
| GO:0032226 | Positive regulation of synaptic transmission, dopaminergic | Decreases phenotype | PMID:26075822 |
| GO:0032349 | Positive regulation of aldosterone biosynthetic process | Increases phenotype | PMID:25617244 |
| GO:0032464 | Positive regulation of protein homooligomerization | Increases phenotype | PMID:27425033 |
| GO:0032922 | Circadian regulation of gene expression | Affects phenotype | PMID:28577110 |
| GO:0032930 | Positive regulation of superoxide anion generation | Increases phenotype | PMID:26187750; PMID:28283350 |
| GO:0032981 | Mitochondrial respiratory chain complex i assembly | Decreases phenotype | PMID:29371327 |
| GO:0033235 | Positive regulation of protein sumoylation | Increases phenotype | PMID:28132806 |
| GO:0033864 | Positive regulation of nad(p)h oxidase activity | Increases phenotype | PMID:29665408 |
| GO:0034101 | Erythrocyte homeostasis | Affects phenotype | PMID:36965781 |
| GO:0034440 | Lipid oxidation | Increases phenotype | PMID:25446674; PMID:25446674; PMID:36706892; PMID:36965781; PMID:25843018; PMID:26276080; PMID:27535828; PMID:27535828; PMID:30472438; PMID:28918840; PMID:30099449; PMID:30141137; PMID:30141137; PMID:31342299; PMID:30141137; PMID:31342299; PMID:31408661; PMID:30472438; PMID:31342299; PMID:31408661; PMID:32937126; PMID:36706892; PMID:36706892; PMID:36965781; PMID:36774383; PMID:36965781; PMID:37394047 |
| GO:0034641 | Cellular nitrogen compound metabolic process | Affects phenotype | PMID:25428620 |
| GO:0035640 | Exploration behavior | Decreases phenotype | PMID:35589691; PMID:35654124; PMID:35654124; PMID:36538285; PMID:35822592; PMID:36538285 |
| GO:0035641 | Locomotory exploration behavior | Decreases phenotype | PMID:32392329 |
| GO:0035752 | Lysosomal lumen ph elevation | Increases phenotype | PMID:31648047 |
| GO:0035794 | Positive regulation of mitochondrial membrane permeability | Increases phenotype | PMID:28703385 |
| GO:0035795 | Negative regulation of mitochondrial membrane permeability | Increases phenotype | PMID:35728354 |
| GO:0036269 | Swimming behavior | Affects phenotype | PMID:35104487 |
| GO:0036343 | Psychomotor behavior | Decreases phenotype | PMID:28238857; PMID:28389404 |
| GO:0036353 | Histone h2a-k119 monoubiquitination | Decreases phenotype | PMID:33157086 |
| GO:0036475 | Neuron death in response to oxidative stress | Increases phenotype | PMID:32913905 |
| GO:0036480 | Neuron intrinsic apoptotic signaling pathway in response to oxidative stress | Increases phenotype | PMID:32913905 |
| GO:0036483 | Neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress | Increases phenotype | PMID:25428620 |
| GO:0036499 | Perk-mediated unfolded protein response | Increases phenotype | PMID:33137417 |
| GO:0040013 | Negative regulation of locomotion | Increases phenotype | PMID:37105514 |
| GO:0040015 | Negative regulation of multicellular organism growth | Increases phenotype | PMID:28374803 |
| GO:0040029 | Epigenetic regulation of gene expression | Affects phenotype | PMID:32178731 |
| GO:0042053 | Regulation of dopamine metabolic process | Affects phenotype | PMID:25446674; PMID:25446674; PMID:25502462; PMID:25502462 |
| GO:0042391 | Regulation of membrane potential | Decreases phenotype | PMID:16624565; PMID:19442964; PMID:28532211 |
| GO:0042415 | Norepinephrine metabolic process | Affects phenotype | PMID:31820278; PMID:34042043; PMID:35104487 |
| GO:0042416 | Dopamine biosynthetic process | Decreases phenotype | PMID:23357119; PMID:27252111; PMID:25481089; PMID:27016191; PMID:27016191; PMID:28238857; PMID:28238857 |
| GO:0042417 | Dopamine metabolic process | Decreases phenotype | PMID:25601988; PMID:27425033; PMID:28585189; PMID:28585189; PMID:32088201; PMID:35187747; PMID:36706892; PMID:30408497; PMID:30408497; PMID:35104487; PMID:31820278; PMID:34042043; PMID:35104487; PMID:35187747; PMID:36706892 |
| GO:0042421 | Norepinephrine biosynthetic process | Decreases phenotype | PMID:25481089 |
| GO:0042427 | Serotonin biosynthetic process | Decreases phenotype | PMID:25481089 |
| GO:0042428 | Serotonin metabolic process | Affects phenotype | PMID:31820278; PMID:34042043; PMID:35104487 |
| GO:0042554 | Superoxide anion generation | Increases phenotype | PMID:20594614; PMID:21216964; PMID:22289031; PMID:32950532; PMID:35544339 |
| GO:0042593 | Glucose homeostasis | Decreases phenotype | PMID:28374803 |
| GO:0042744 | Hydrogen peroxide catabolic process | Increases phenotype | PMID:20558743 |
| GO:0042755 | Eating behavior | Affects phenotype | PMID:36538285 |
| GO:0042775 | Mitochondrial atp synthesis coupled electron transport | Decreases phenotype | PMID:25746382 |
| GO:0043005 | Neuron projection | Decreases phenotype | PMID:37210002 |
| GO:0043025 | Neuronal cell body | Decreases phenotype | PMID:27585560 |
| GO:0043065 | Positive regulation of apoptotic process | Increases phenotype | PMID:25247703; PMID:25247703; PMID:25423838; PMID:28132806; PMID:25423838; PMID:25502462; PMID:25991017; PMID:25991017; PMID:26276080; PMID:26864693; PMID:29371327; PMID:30141137; PMID:31342299; PMID:31408661; PMID:26141520; PMID:26276080; PMID:26864693; PMID:28132806; PMID:28348719; PMID:29095437; PMID:29371327; PMID:30141137; PMID:30673822; PMID:31342299; PMID:33137417; PMID:33402167 |
| GO:0043248 | Proteasome assembly | Increases phenotype | PMID:27345029 |
| GO:0043249 | Erythrocyte maturation | Increases phenotype | PMID:28374803 |
| GO:0043473 | Pigmentation | Affects phenotype | PMID:32937126 |
| GO:0043525 | Positive regulation of neuron apoptotic process | Increases phenotype | PMID:27108097; PMID:27535828; PMID:29458170; PMID:32949572 |
| GO:0043931 | Ossification involved in bone maturation | Decreases phenotype | PMID:28374803 |
| GO:0043966 | Histone h3 acetylation | Increases phenotype | PMID:35104487 |
| GO:0044237 | Cellular metabolic process | Increases phenotype | PMID:25446015; PMID:30408497; PMID:30408497; PMID:32001317; PMID:33512557; PMID:34182063; PMID:34602532; PMID:37156403; PMID:31648047; PMID:31814881; PMID:32033040; PMID:32553934; PMID:32606391; PMID:32607615; PMID:32607615; PMID:34642769; PMID:32870474; PMID:33512557; PMID:33515431; PMID:34021431; PMID:34029635; PMID:34182063; PMID:34391968; PMID:34642769; PMID:34808100; PMID:35544339; PMID:35589691; PMID:36400285; PMID:36446982; PMID:36586010; PMID:37394047; PMID:37979659 |
| GO:0044319 | Wound healing, spreading of cells | Increases phenotype | PMID:24316229; PMID:30857887 |
| GO:0044754 | Autolysosome | Increases phenotype | PMID:31648047 |
| GO:0045333 | Cellular respiration | Increases phenotype | PMID:11164812; PMID:16580092; PMID:17123556; PMID:19923925; PMID:21907265; PMID:23000518; PMID:24374061; PMID:24374061; PMID:28359145; PMID:24732427; PMID:27545309; PMID:31629068; PMID:31958483; PMID:32607615; PMID:33512557 |
| GO:0045429 | Positive regulation of nitric oxide biosynthetic process | Increases phenotype | PMID:23593274; PMID:25247703; PMID:28110601; PMID:29906494; PMID:30141137; PMID:30686998 |
| GO:0045454 | Cell redox homeostasis | Decreases phenotype | PMID:25448047; PMID:30141137; PMID:30472438; PMID:31251943; PMID:35919817; PMID:36048341; PMID:37105514; PMID:37224993 |
| GO:0045821 | Positive regulation of glycolytic process | Increases phenotype | PMID:25746382; PMID:31974165; PMID:33137417 |
| GO:0045907 | Positive regulation of vasoconstriction | Increases phenotype | PMID:11964372 |
| GO:0045919 | Positive regulation of cytolysis | Increases phenotype | PMID:30207190; PMID:31342299; PMID:31342299; PMID:31926197; PMID:32368861; PMID:31926197; PMID:32368861 |
| GO:0045930 | Negative regulation of mitotic cell cycle | Increases phenotype | PMID:18538940 |
| GO:0045931 | Positive regulation of mitotic cell cycle | Decreases phenotype | PMID:25991017 |
| GO:0045964 | Positive regulation of dopamine metabolic process | Increases phenotype | PMID:37105514 |
| GO:0046034 | Atp metabolic process | Increases phenotype | PMID:24732427; PMID:28703385; PMID:30141137; PMID:31820278; PMID:31974165; PMID:32606391; PMID:32949729; PMID:33512557; PMID:33515431; PMID:34642769; PMID:35253580; PMID:35544339; PMID:37156403 |
| GO:0046058 | Camp metabolic process | Affects phenotype | PMID:25446674; PMID:25446674; PMID:36706892; PMID:36706892 |
| GO:0046209 | Nitric oxide metabolic process | Affects phenotype | PMID:31714633 |
| GO:0046415 | Urate metabolic process | Decreases phenotype | PMID:28374803; PMID:30099449 |
| GO:0046449 | Creatinine metabolic process | Decreases phenotype | PMID:30099449 |
| GO:0046466 | Membrane lipid catabolic process | Affects phenotype | PMID:10967318; PMID:15647387; PMID:15720824; PMID:28962525; PMID:3453688; PMID:35337893 |
| GO:0046500 | S-adenosylmethionine metabolic process | Increases phenotype | PMID:30673822 |
| GO:0046621 | Negative regulation of organ growth | Increases phenotype | PMID:28374803 |
| GO:0046701 | Insecticide catabolic process | Decreases phenotype | PMID:9282833 |
| GO:0046722 | Lactic acid secretion | Increases phenotype | PMID:28374803 |
| GO:0048143 | Astrocyte activation | Increases phenotype | PMID:27316720; PMID:32088201; PMID:35654124; PMID:35654124; PMID:36538285; PMID:35822592; PMID:36538285; PMID:36965781 |
| GO:0048386 | Positive regulation of retinoic acid receptor signaling pathway | Increases phenotype | PMID:30818834 |
| GO:0048675 | Axon extension | Decreases phenotype | PMID:38960072 |
| GO:0048812 | Neuron projection morphogenesis | Decreases phenotype | PMID:29955902 |
| GO:0050665 | Hydrogen peroxide biosynthetic process | Increases phenotype | PMID:18022205; PMID:20594614; PMID:20594614; PMID:23189969; PMID:23189969; PMID:27535828 |
| GO:0050729 | Positive regulation of inflammatory response | Increases phenotype | PMID:23593274; PMID:30099449; PMID:30686998 |
| GO:0050765 | Negative regulation of phagocytosis | Increases phenotype | PMID:30686998 |
| GO:0050766 | Positive regulation of phagocytosis | Affects phenotype | PMID:23593274 |
| GO:0050881 | Musculoskeletal movement | Increases phenotype | PMID:27108097 |
| GO:0050885 | Neuromuscular process controlling balance | Affects phenotype | PMID:31814881; PMID:31814881; PMID:32088201; PMID:32088201 |
| GO:0050890 | Cognition | Decreases phenotype | PMID:35833337; PMID:36553663 |
| GO:0050905 | Neuromuscular process | Affects phenotype | PMID:35654124 |
| GO:0050957 | Equilibrioception | Decreases phenotype | PMID:28238857 |
| GO:0050994 | Regulation of lipid catabolic process | Increases phenotype | PMID:37105514 |
| GO:0050996 | Positive regulation of lipid catabolic process | Increases phenotype | PMID:33402167; PMID:37224993 |
| GO:0051156 | Glucose 6-phosphate metabolic process | Increases phenotype | PMID:31974165 |
| GO:0051480 | Regulation of cytosolic calcium ion concentration | Increases phenotype | PMID:11964372 |
| GO:0051646 | Mitochondrion localization | Decreases phenotype | PMID:21907265 |
| GO:0051881 | Regulation of mitochondrial membrane potential | Increases phenotype | PMID:11164812; PMID:16402917; PMID:16580092; PMID:17123556; PMID:19442964; PMID:19777565; PMID:20594614; PMID:20594614; PMID:29183837; PMID:30905860; PMID:32001317; PMID:33512557; PMID:37482139; PMID:21223980; PMID:21907265; PMID:22928487; PMID:23963993; PMID:24374061; PMID:24374061; PMID:27053302; PMID:25263579; PMID:26739068; PMID:27053302; PMID:27180985; PMID:29174113; PMID:29183837; PMID:29428530; PMID:32392329; PMID:32607615; PMID:32607615; PMID:34642769; PMID:33515431; PMID:33823232; PMID:34808100; PMID:35253580; PMID:36446982; PMID:37046073; PMID:37482139; PMID:37979659 |
| GO:0051882 | Mitochondrial depolarization | Increases phenotype | PMID:31342299 |
| GO:0051899 | Membrane depolarization | Increases phenotype | PMID:37979659 |
| GO:0051901 | Positive regulation of mitochondrial depolarization | Increases phenotype | PMID:26358042 |
| GO:0055005 | Ventricular cardiac myofibril assembly | Decreases phenotype | PMID:31585160 |
| GO:0055074 | Calcium ion homeostasis | Affects phenotype | PMID:35187747; PMID:36774383 |
| GO:0060291 | Long-term synaptic potentiation | Affects phenotype | PMID:26916954 |
| GO:0060292 | Long-term synaptic depression | Affects phenotype | PMID:26916954 |
| GO:0060319 | Primitive erythrocyte differentiation | Decreases phenotype | PMID:28374803 |
| GO:0061024 | Membrane organization | Decreases phenotype | PMID:28245986 |
| GO:0061518 | Microglial cell proliferation | Increases phenotype | PMID:30408497 |
| GO:0061577 | Calcium ion transmembrane transport via high voltage-gated calcium channel | Increases phenotype | PMID:30859212 |
| GO:0061726 | Mitochondrion disassembly | Increases phenotype | PMID:26141520 |
| GO:0061734 | Parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization | Affects phenotype | PMID:32392329 |
| GO:0061739 | Protein lipidation involved in autophagosome assembly | Decreases phenotype | PMID:30141137; PMID:30141137; PMID:31926197; PMID:31926197; PMID:33137417 |
| GO:0061744 | Motor behavior | Decreases phenotype | PMID:31820278; PMID:35833337; PMID:36048341 |
| GO:0061900 | Glial cell activation | Increases phenotype | PMID:30001633; PMID:37224993 |
| GO:0070265 | Necrotic cell death | Increases phenotype | PMID:35337893 |
| GO:0070318 | Positive regulation of g0 to g1 transition | Increases phenotype | PMID:32368861 |
| GO:0070328 | Triglyceride homeostasis | Decreases phenotype | PMID:28374803 |
| GO:0070994 | Detection of oxidative stress | Increases phenotype | PMID:34042043; PMID:34391968; PMID:35187747; PMID:35187747; PMID:36538285; PMID:36965781; PMID:35187747; PMID:36965781; PMID:35253580; PMID:36400285; PMID:36538285; PMID:36965781; PMID:37394047 |
| GO:0070997 | Neuron death | Increases phenotype | PMID:20038714; PMID:25461191; PMID:27316720; PMID:27316720; PMID:28585189; PMID:28585189; PMID:31714633; PMID:32033040; PMID:36538285; PMID:36774383; PMID:36774383; PMID:38960072; PMID:38960072 |
| GO:0072593 | Reactive oxygen species metabolic process | Increases phenotype | PMID:22928487; PMID:23144690; PMID:23963993; PMID:24002177; PMID:24140496; PMID:24188932; PMID:24304935; PMID:24304935; PMID:24374061; PMID:24451142; PMID:24631677; PMID:24755484; PMID:24374061; PMID:24451142; PMID:24732427; PMID:24755484; PMID:25086357; PMID:25136123; PMID:25263579; PMID:25496994; PMID:25725130; PMID:31953210; PMID:32092105; PMID:32115830; PMID:33515431; PMID:34182063; PMID:34182063; PMID:34602532; PMID:34602532; PMID:34808100; PMID:35544339; PMID:36446982; PMID:37659621 |
| GO:0072656 | Maintenance of protein location in mitochondrion | Decreases phenotype | PMID:28940366 |
| GO:0080129 | Proteasome core complex assembly | Increases phenotype | PMID:31969611 |
| GO:0090150 | Establishment of protein localization to membrane | Increases phenotype | PMID:28283350 |
| GO:0090200 | Positive regulation of release of cytochrome c from mitochondria | Increases phenotype | PMID:28703385 |
| GO:0090261 | Positive regulation of inclusion body assembly | Increases phenotype | PMID:25247703 |
| GO:0090327 | Negative regulation of locomotion involved in locomotory behavior | Increases phenotype | PMID:32860006 |
| GO:0090363 | Regulation of proteasome core complex assembly | Affects phenotype | PMID:37105514 |
| GO:0090494 | Dopamine uptake | Affects phenotype | PMID:30769001 |
| GO:0090648 | Response to environmental enrichment | Decreases phenotype | PMID:36553663 |
| GO:0090659 | Walking behavior | Affects phenotype | PMID:31714633 |
| GO:0090728 | Negative regulation of brood size | Increases phenotype | PMID:32937126 |
| GO:0097189 | Apoptotic body | Increases phenotype | PMID:36446982 |
| GO:0097449 | Astrocyte projection | Affects phenotype | PMID:38960072 |
| GO:0097621 | Monoamine oxidase activity | Increases phenotype | PMID:35187747 |
| GO:0097707 | Ferroptosis | Affects phenotype | PMID:34391968 |
| GO:0120054 | Intestinal motility | Decreases phenotype | PMID:36965781 |
| GO:0140042 | Lipid droplet formation | Increases phenotype | PMID:37046073 |
| GO:0140121 | Lewy body formation | Increases phenotype | PMID:30408497 |
| GO:0140124 | Positive regulation of lewy body formation | Increases phenotype | PMID:31022188 |
| GO:0140655 | Mitochondrial proliferation | Decreases phenotype | PMID:32860006 |
| GO:0150103 | Reactive gliosis | Increases phenotype | PMID:35654124 |
| GO:0160020 | Positive regulation of ferroptosis | Increases phenotype | PMID:35919817 |
| GO:1900015 | Regulation of cytokine production involved in inflammatory response | Affects phenotype | PMID:28903492 |
| GO:1900017 | Positive regulation of cytokine production involved in inflammatory response | Increases phenotype | PMID:28903492 |
| GO:1900114 | Positive regulation of histone h3-k9 trimethylation | Decreases phenotype | PMID:25991017 |
| GO:1900227 | Positive regulation of nlrp3 inflammasome complex assembly | Increases phenotype | PMID:26086368 |
| GO:1900745 | Positive regulation of p38mapk cascade | Increases phenotype | PMID:17395008; PMID:29906494 |
| GO:1901215 | Negative regulation of neuron death | Increases phenotype | PMID:32481507 |
| GO:1901216 | Positive regulation of neuron death | Increases phenotype | PMID:14521988; PMID:26276080; PMID:26864693; PMID:28283350; PMID:28903492; PMID:28903492; PMID:32189544; PMID:28918840; PMID:31022188; PMID:31251943; PMID:31969611; PMID:32189544; PMID:37224993 |
| GO:1901670 | Negative regulation of superoxide dismutase activity | Increases phenotype | PMID:29665408; PMID:30472438; PMID:31251943; PMID:31408661 |
| GO:1901671 | Positive regulation of superoxide dismutase activity | Decreases phenotype | PMID:25843018; PMID:26276080; PMID:27108097 |
| GO:1901687 | Glutathione derivative biosynthetic process | Decreases phenotype | PMID:23357119 |
| GO:1901696 | Cannabinoid biosynthetic process | Increases phenotype | PMID:27317300 |
| GO:1901741 | Positive regulation of myoblast fusion | Decreases phenotype | PMID:25827955 |
| GO:1901856 | Negative regulation of cellular respiration | Increases phenotype | PMID:33070465 |
| GO:1901857 | Positive regulation of cellular respiration | Decreases phenotype | PMID:26958860 |
| GO:1901990 | Regulation of mitotic cell cycle phase transition | Increases phenotype | PMID:30857887 |
| GO:1902512 | Positive regulation of apoptotic dna fragmentation | Increases phenotype | PMID:27535828 |
| GO:1902603 | Carnitine transmembrane transport | Decreases phenotype | PMID:28298333 |
| GO:1902882 | Regulation of response to oxidative stress | Decreases phenotype | PMID:28526446 |
| GO:1902941 | Regulation of voltage-gated chloride channel activity | Affects phenotype | PMID:33512997 |
| GO:1902957 | Negative regulation of mitochondrial electron transport, nadh to ubiquinone | Affects phenotype | PMID:28374803; PMID:29095437; PMID:29371327; PMID:29371327; PMID:30141137; PMID:30141137; PMID:30328585; PMID:30472438; PMID:32937126 |
| GO:1902958 | Positive regulation of mitochondrial electron transport, nadh to ubiquinone | Decreases phenotype | PMID:24295472; PMID:25446674; PMID:25693864; PMID:27510327 |
| GO:1903047 | Mitotic cell cycle process | Affects phenotype | PMID:37394047 |
| GO:1903180 | Negative regulation of dopamine biosynthetic process | Increases phenotype | PMID:37105514 |
| GO:1903181 | Positive regulation of dopamine biosynthetic process | Decreases phenotype | PMID:28526446 |
| GO:1903283 | Negative regulation of glutathione peroxidase activity | Increases phenotype | PMID:30472438; PMID:31408661 |
| GO:1903378 | Positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway | Increases phenotype | PMID:25304210 |
| GO:1903409 | Reactive oxygen species biosynthetic process | Increases phenotype | PMID:21368743; PMID:22041943; PMID:22041943; PMID:27053302; PMID:27345029; PMID:28245986; PMID:28359145; PMID:29134401; PMID:23816754; PMID:24316229; PMID:25446015; PMID:26446018; PMID:26739068; PMID:26770656; PMID:26770656; PMID:27180985; PMID:28245986; PMID:27053302; PMID:27133439; PMID:27180985; PMID:28245986; PMID:27867098; PMID:28245986; PMID:28315715; PMID:28728140; PMID:29134401; PMID:29428530; PMID:30857887; PMID:30951809 |
| GO:1903426 | Regulation of reactive oxygen species biosynthetic process | Affects phenotype | PMID:30673822 |
| GO:1903428 | Positive regulation of reactive oxygen species biosynthetic process | Increases phenotype | PMID:23593274; PMID:24295472; PMID:24307199; PMID:25163676; PMID:25247703; PMID:25247703; PMID:28774849; PMID:31251943; PMID:32937854; PMID:25423838; PMID:25428620; PMID:25693864; PMID:25827955; PMID:26086368; PMID:26276080; PMID:26276080; PMID:28774849; PMID:30141137; PMID:31342299; PMID:31408661; PMID:26968795; PMID:27108097; PMID:27510327; PMID:28283350; PMID:28348719; PMID:28703385; PMID:28724416; PMID:28774849; PMID:29095437; PMID:29665408; PMID:29906494; PMID:30141137; PMID:30472438; PMID:30927257; PMID:31022188; PMID:31251943; PMID:31342299; PMID:31926197; PMID:32392329; PMID:32522578; PMID:32913905; PMID:32937854; PMID:35728354 |
| GO:1903578 | Regulation of atp metabolic process | Affects phenotype | PMID:25446674; PMID:25446674; PMID:25502462; PMID:25502462; PMID:27510327 |
| GO:1903749 | Positive regulation of establishment of protein localization to mitochondrion | Increases phenotype | PMID:28348719 |
| GO:1903787 | Negative regulation of glutathione biosynthetic process | Increases phenotype | PMID:33402167 |
| GO:1903862 | Positive regulation of oxidative phosphorylation | Decreases phenotype | PMID:24403227; PMID:25746382 |
| GO:1903979 | Negative regulation of microglial cell activation | Increases phenotype | PMID:30686998 |
| GO:1903980 | Positive regulation of microglial cell activation | Increases phenotype | PMID:27317300; PMID:28283350; PMID:32189544; PMID:33402167 |
| GO:1904124 | Microglial cell migration | Increases phenotype | PMID:23816754 |
| GO:1904648 | Cellular response to rotenone | Increases phenotype | PMID:12496265; PMID:21907265; PMID:23593274; PMID:25502462; PMID:28110601; PMID:28132806; PMID:29665408 |
| GO:1905447 | Negative regulation of mitochondrial atp synthesis coupled electron transport | Increases phenotype | PMID:34302933 |
| GO:1905457 | Negative regulation of lymphoid progenitor cell differentiation | Increases phenotype | PMID:28374803 |
| GO:1905898 | Positive regulation of response to endoplasmic reticulum stress | Increases phenotype | PMID:26864693; PMID:26864693; PMID:30141137; PMID:30141137 |
| GO:1990138 | Neuron projection extension | Affects phenotype | PMID:29955902; PMID:30769001; PMID:32033040; PMID:32481507 |
| GO:1990182 | Exosomal secretion | Increases phenotype | PMID:25682864 |
| GO:1990787 | Negative regulation of hh target transcription factor activity | Increases phenotype | PMID:30818834 |
| GO:2000060 | Positive regulation of ubiquitin-dependent protein catabolic process | Increases phenotype | PMID:25247703 |
| GO:2000170 | Positive regulation of peptidyl-cysteine s-nitrosylation | Increases phenotype | PMID:25247703 |
| GO:2000573 | Positive regulation of dna biosynthetic process | Affects phenotype | PMID:14656924 |
| GO:2000617 | Positive regulation of histone h3-k9 acetylation | Increases phenotype | PMID:20705415; PMID:25991017 |
| GO:2000774 | Positive regulation of cellular senescence | Increases phenotype | PMID:32949572 |
| GO:2000786 | Positive regulation of autophagosome assembly | Increases phenotype | PMID:26031332 |
| GO:2001025 | Positive regulation of response to drug | Increases phenotype | PMID:28918840 |
| GO:2001170 | Negative regulation of atp biosynthetic process | Increases phenotype | PMID:29107957; PMID:30673822; PMID:30686998; PMID:31022188; PMID:35728354; PMID:37473966 |
| GO:2001171 | Positive regulation of atp biosynthetic process | Decreases phenotype | PMID:26141520 |
We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.