| GO ID | GO name | Interaction type | Reference |
|---|---|---|---|
| GO:0004364 | Glutathione transferase activity | Decreases phenotype | PMID:30359721 |
| GO:0004743 | Pyruvate kinase activity | Decreases phenotype | PMID:31647946 |
| GO:0006749 | Glutathione metabolic process | Affects phenotype | PMID:36646412 |
| GO:0006750 | Glutathione biosynthetic process | Decreases phenotype | PMID:30359721 |
| GO:0006754 | Atp biosynthetic process | Decreases phenotype | PMID:31647946 |
| GO:0006810 | Transport | Affects phenotype | PMID:23503628 |
| GO:0006915 | Apoptotic process | Increases phenotype | PMID:32179164 |
| GO:0006954 | Inflammatory response | Affects phenotype | PMID:23503628 |
| GO:0006979 | Response to oxidative stress | Affects phenotype | PMID:23503628 |
| GO:0007283 | Spermatogenesis | Affects phenotype | PMID:31647946 |
| GO:0008137 | Nadh dehydrogenase (ubiquinone) activity | Decreases phenotype | PMID:31647946 |
| GO:0008177 | Succinate dehydrogenase (ubiquinone) activity | Decreases phenotype | PMID:31647946 |
| GO:0008542 | Visual learning | Decreases phenotype | PMID:30836164 |
| GO:0008584 | Male gonad development | Affects phenotype | PMID:31647946 |
| GO:0010942 | Positive regulation of cell death | Increases phenotype | PMID:22941203; PMID:25410796 |
| GO:0016042 | Lipid catabolic process | Increases phenotype | PMID:17503410 |
| GO:0018394 | Peptidyl-lysine acetylation | Decreases phenotype | PMID:31647946 |
| GO:0030642 | Cellular sulfate ion homeostasis | Decreases phenotype | PMID:22941203 |
| GO:0035176 | Social behavior | Decreases phenotype | PMID:30836164 |
| GO:0036050 | Peptidyl-lysine succinylation | Decreases phenotype | PMID:31647946 |
| GO:0043065 | Positive regulation of apoptotic process | Increases phenotype | PMID:24419708 |
| GO:0045429 | Positive regulation of nitric oxide biosynthetic process | Decreases phenotype | PMID:25410796 |
| GO:0046330 | Positive regulation of jnk cascade | Increases phenotype | PMID:24419708 |
| GO:0070994 | Detection of oxidative stress | Increases phenotype | PMID:36646412 |
| GO:0071284 | Cellular response to lead ion | Affects phenotype | PMID:23503628 |
| GO:0090559 | Regulation of membrane permeability | Decreases phenotype | PMID:22941203 |
| GO:0097623 | Potassium ion export across plasma membrane | Increases phenotype | PMID:22941203 |
| GO:0098727 | Maintenance of cell number | Affects phenotype | PMID:30836164 |
| GO:1901856 | Negative regulation of cellular respiration | Increases phenotype | PMID:33320250 |
| GO:1903409 | Reactive oxygen species biosynthetic process | Affects phenotype | PMID:30359721; PMID:31647946 |
| GO:1903428 | Positive regulation of reactive oxygen species biosynthetic process | Increases phenotype | PMID:25410796 |
We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.