| GO ID | GO name | Interaction type | Reference |
|---|---|---|---|
| GO:0000080 | Mitotic g1 phase | Affects phenotype | PMID:36828243 |
| GO:0000084 | Mitotic s phase | Affects phenotype | PMID:36828243 |
| GO:0000086 | G2/m transition of mitotic cell cycle | Affects phenotype | PMID:28415704 |
| GO:0001541 | Ovarian follicle development | Decreases phenotype | PMID:29969652; PMID:34597818; PMID:35762964; PMID:37277016; PMID:37439711 |
| GO:0001547 | Antral ovarian follicle growth | Decreases phenotype | PMID:28013214; PMID:28486587 |
| GO:0001552 | Ovarian follicle atresia | Increases phenotype | PMID:37505531 |
| GO:0001568 | Blood vessel development | Increases phenotype | PMID:37021957 |
| GO:0001780 | Neutrophil homeostasis | Decreases phenotype | PMID:38285958; PMID:39631539 |
| GO:0001812 | Positive regulation of type i hypersensitivity | Increases phenotype | PMID:38157815 |
| GO:0001822 | Kidney development | Affects phenotype | PMID:28415704 |
| GO:0001836 | Release of cytochrome c from mitochondria | Increases phenotype | PMID:30910607 |
| GO:0001837 | Epithelial to mesenchymal transition | Increases phenotype | PMID:32860865 |
| GO:0001892 | Embryonic placenta development | Decreases phenotype | PMID:40221850 |
| GO:0001974 | Blood vessel remodeling | Increases phenotype | PMID:38944327 |
| GO:0002176 | Male germ cell proliferation | Increases phenotype | PMID:34280466 |
| GO:0002260 | Lymphocyte homeostasis | Affects phenotype | PMID:39631539 |
| GO:0002277 | Myeloid dendritic cell activation involved in immune response | Increases phenotype | PMID:30503584 |
| GO:0002523 | Leukocyte migration involved in inflammatory response | Increases phenotype | PMID:30551395; PMID:35378083 |
| GO:0002606 | Positive regulation of dendritic cell antigen processing and presentation | Increases phenotype | PMID:30503584 |
| GO:0003006 | Developmental process involved in reproduction | Affects phenotype | PMID:37788136 |
| GO:0003014 | Renal system process | Decreases phenotype | PMID:30660848 |
| GO:0003093 | Regulation of glomerular filtration | Affects phenotype | PMID:32645486 |
| GO:0004022 | Alcohol dehydrogenase (nad+) activity | Decreases phenotype | PMID:34534558 |
| GO:0004096 | Catalase activity | Increases phenotype | PMID:39631539 |
| GO:0004303 | Estradiol 17-beta-dehydrogenase activity | Decreases phenotype | PMID:22489061 |
| GO:0004364 | Glutathione transferase activity | Increases phenotype | PMID:39631539 |
| GO:0004457 | Lactate dehydrogenase activity | Increases phenotype | PMID:27581038; PMID:33254669 |
| GO:0004602 | Glutathione peroxidase activity | Decreases phenotype | PMID:33508418 |
| GO:0004691 | Camp-dependent protein kinase activity | Increases phenotype | PMID:33711355 |
| GO:0004784 | Superoxide dismutase activity | Affects phenotype | PMID:28295950; PMID:33508418; PMID:34097988; PMID:34793900; PMID:34864091; PMID:37277016; PMID:39631539 |
| GO:0005739 | Mitochondrion | Decreases phenotype | PMID:31712109 |
| GO:0005776 | Autophagosome | Increases phenotype | PMID:37277016 |
| GO:0005977 | Glycogen metabolic process | Affects phenotype | PMID:39631539 |
| GO:0006006 | Glucose metabolic process | Affects phenotype | PMID:39631539 |
| GO:0006085 | Acetyl-coa biosynthetic process | Increases phenotype | PMID:33167028 |
| GO:0006171 | Camp biosynthetic process | Increases phenotype | PMID:32126385; PMID:37552060 |
| GO:0006264 | Mitochondrial dna replication | Decreases phenotype | PMID:30910607 |
| GO:0006304 | Dna modification | Increases phenotype | PMID:30952838 |
| GO:0006306 | Dna methylation | Decreases phenotype | PMID:30952838 |
| GO:0006497 | Protein lipidation | Increases phenotype | PMID:37277016 |
| GO:0006590 | Thyroid hormone generation | Decreases phenotype | PMID:31979393 |
| GO:0006641 | Triglyceride metabolic process | Affects phenotype | PMID:33508418 |
| GO:0006694 | Steroid biosynthetic process | Decreases phenotype | PMID:35762964 |
| GO:0006695 | Cholesterol biosynthetic process | Decreases phenotype | PMID:31979393 |
| GO:0006749 | Glutathione metabolic process | Affects phenotype | PMID:33508418; PMID:39631539 |
| GO:0006750 | Glutathione biosynthetic process | Decreases phenotype | PMID:28295950; PMID:30776390; PMID:31712109 |
| GO:0006754 | Atp biosynthetic process | Decreases phenotype | PMID:30910607 |
| GO:0006869 | Lipid transport | Decreases phenotype | PMID:40221850 |
| GO:0006884 | Cell volume homeostasis | Affects phenotype | PMID:39631539 |
| GO:0006909 | Phagocytosis | Decreases phenotype | PMID:26133781; PMID:30350139 |
| GO:0006915 | Apoptotic process | Affects phenotype | PMID:24285609; PMID:28067064; PMID:28295950; PMID:28295950; PMID:30952838; PMID:28415704; PMID:28486587; PMID:30173778; PMID:30776390; PMID:30910607; PMID:30910607; PMID:30952838; PMID:30952838; PMID:33729022; PMID:35605887; PMID:35690178; PMID:36828243 |
| GO:0006919 | Activation of cysteine-type endopeptidase activity involved in apoptotic process | Increases phenotype | PMID:33336902 |
| GO:0006954 | Inflammatory response | Increases phenotype | PMID:33508418 |
| GO:0006974 | Cellular response to dna damage stimulus | Increases phenotype | PMID:28893613 |
| GO:0007005 | Mitochondrion organization | Decreases phenotype | PMID:30910607; PMID:31712109 |
| GO:0007029 | Endoplasmic reticulum organization | Decreases phenotype | PMID:26706031 |
| GO:0007204 | Positive regulation of cytosolic calcium ion concentration | Increases phenotype | PMID:26804720 |
| GO:0007281 | Germ cell development | Decreases phenotype | PMID:21868749; PMID:30802670; PMID:32525071; PMID:37788136 |
| GO:0007283 | Spermatogenesis | Decreases phenotype | PMID:17003688; PMID:25172463; PMID:30934153; PMID:28067064; PMID:29029336; PMID:30802670; PMID:30952838; PMID:33086118; PMID:33331133; PMID:35605887; PMID:36215882; PMID:36602389; PMID:37364641; PMID:37505531 |
| GO:0007286 | Spermatid development | Decreases phenotype | PMID:30802670; PMID:34280466 |
| GO:0007611 | Learning or memory | Decreases phenotype | PMID:33336902 |
| GO:0007613 | Memory | Affects phenotype | PMID:30776390 |
| GO:0007631 | Feeding behavior | Affects phenotype | PMID:31979393 |
| GO:0008203 | Cholesterol metabolic process | Affects phenotype | PMID:32417575; PMID:33508418 |
| GO:0008209 | Androgen metabolic process | Affects phenotype | PMID:27148549 |
| GO:0008210 | Estrogen metabolic process | Affects phenotype | PMID:28611354; PMID:34597818 |
| GO:0008219 | Cell death | Affects phenotype | PMID:20650509; PMID:33711355 |
| GO:0008283 | Cell population proliferation | Affects phenotype | PMID:19591892; PMID:28295950; PMID:30952838; PMID:34428494; PMID:36708983; PMID:36828243 |
| GO:0008284 | Positive regulation of cell population proliferation | Affects phenotype | PMID:25369342; PMID:29074358; PMID:35028925 |
| GO:0008285 | Negative regulation of cell population proliferation | Increases phenotype | PMID:33091774; PMID:35739755; PMID:39151608 |
| GO:0008361 | Regulation of cell size | Affects phenotype | PMID:32525071 |
| GO:0008584 | Male gonad development | Increases phenotype | PMID:20002220; PMID:28067064; PMID:35690178; PMID:28611354; PMID:30802670; PMID:30952838; PMID:34280466 |
| GO:0009008 | Dna-methyltransferase activity | Affects phenotype | PMID:31956671 |
| GO:0009410 | Response to xenobiotic stimulus | Increases phenotype | PMID:30503584 |
| GO:0009566 | Fertilization | Decreases phenotype | PMID:33711355 |
| GO:0009790 | Embryo development | Decreases phenotype | PMID:33711355 |
| GO:0009838 | Abscission | Affects phenotype | PMID:34280466 |
| GO:0010468 | Regulation of gene expression | Affects phenotype | PMID:38995844 |
| GO:0010508 | Positive regulation of autophagy | Increases phenotype | PMID:26804720; PMID:30453174 |
| GO:0010718 | Positive regulation of epithelial to mesenchymal transition | Increases phenotype | PMID:30453174; PMID:37356649 |
| GO:0010719 | Negative regulation of epithelial to mesenchymal transition | Increases phenotype | PMID:32028152 |
| GO:0010867 | Positive regulation of triglyceride biosynthetic process | Increases phenotype | PMID:33167028 |
| GO:0010906 | Regulation of glucose metabolic process | Affects phenotype | PMID:35739755; PMID:37364641 |
| GO:0010907 | Positive regulation of glucose metabolic process | Increases phenotype | PMID:32810643 |
| GO:0010940 | Positive regulation of necrotic cell death | Increases phenotype | PMID:25172463; PMID:38285958 |
| GO:0010942 | Positive regulation of cell death | Increases phenotype | PMID:25172463 |
| GO:0010983 | Positive regulation of high-density lipoprotein particle clearance | Increases phenotype | PMID:33167028 |
| GO:0010989 | Negative regulation of low-density lipoprotein particle clearance | Increases phenotype | PMID:33167028 |
| GO:0014067 | Negative regulation of phosphatidylinositol 3-kinase signaling | Increases phenotype | PMID:29526571 |
| GO:0016042 | Lipid catabolic process | Increases phenotype | PMID:28295950; PMID:30776390; PMID:32525071; PMID:33508418; PMID:34097988 |
| GO:0016525 | Negative regulation of angiogenesis | Increases phenotype | PMID:38184977 |
| GO:0018108 | Peptidyl-tyrosine phosphorylation | Increases phenotype | PMID:33711355 |
| GO:0018158 | Protein oxidation | Decreases phenotype | PMID:34793900 |
| GO:0019432 | Triglyceride biosynthetic process | Increases phenotype | PMID:31979393 |
| GO:0019627 | Urea metabolic process | Affects phenotype | PMID:33729022 |
| GO:0019752 | Carboxylic acid metabolic process | Affects phenotype | PMID:36529159 |
| GO:0019911 | Structural constituent of myelin sheath | Affects phenotype | PMID:35690178 |
| GO:0022602 | Ovulation cycle process | Affects phenotype | PMID:29969652 |
| GO:0030199 | Collagen fibril organization | Increases phenotype | PMID:35690178 |
| GO:0030225 | Macrophage differentiation | Increases phenotype | PMID:30218697 |
| GO:0030263 | Apoptotic chromosome condensation | Increases phenotype | PMID:28611354; PMID:29029336 |
| GO:0030335 | Positive regulation of cell migration | Increases phenotype | PMID:37356649 |
| GO:0030336 | Negative regulation of cell migration | Increases phenotype | PMID:32028152; PMID:38184977 |
| GO:0030728 | Ovulation | Increases phenotype | PMID:33316053 |
| GO:0030850 | Prostate gland development | Decreases phenotype | PMID:30802670 |
| GO:0031589 | Cell-substrate adhesion | Affects phenotype | PMID:34902519; PMID:38944327 |
| GO:0032148 | Activation of protein kinase b activity | Decreases phenotype | PMID:29526571 |
| GO:0032308 | Positive regulation of prostaglandin secretion | Increases phenotype | PMID:33316053 |
| GO:0032930 | Positive regulation of superoxide anion generation | Increases phenotype | PMID:33348264 |
| GO:0033148 | Positive regulation of intracellular estrogen receptor signaling pathway | Increases phenotype | PMID:25449125 |
| GO:0033344 | Cholesterol efflux | Increases phenotype | PMID:32417575 |
| GO:0034199 | Activation of protein kinase a activity | Increases phenotype | PMID:37552060 |
| GO:0034440 | Lipid oxidation | Increases phenotype | PMID:25172463; PMID:36215882 |
| GO:0034976 | Response to endoplasmic reticulum stress | Affects phenotype | PMID:26804720 |
| GO:0035116 | Embryonic hindlimb morphogenesis | Decreases phenotype | PMID:24503621 |
| GO:0035148 | Tube formation | Affects phenotype | PMID:38944327 |
| GO:0035176 | Social behavior | Decreases phenotype | PMID:32518293 |
| GO:0035936 | Testosterone secretion | Decreases phenotype | PMID:28013214; PMID:28528174; PMID:30802670; PMID:31199487; PMID:38769170 |
| GO:0035937 | Estrogen secretion | Affects phenotype | PMID:30310660 |
| GO:0035938 | Estradiol secretion | Decreases phenotype | PMID:28013214 |
| GO:0035941 | Androstenedione secretion | Decreases phenotype | PMID:28013214 |
| GO:0035943 | Estrone secretion | Decreases phenotype | PMID:28013214 |
| GO:0036126 | Sperm flagellum | Affects phenotype | PMID:36215882 |
| GO:0036269 | Swimming behavior | Decreases phenotype | PMID:32518293; PMID:33336902 |
| GO:0036336 | Dendritic cell migration | Increases phenotype | PMID:29198882; PMID:30503584 |
| GO:0036343 | Psychomotor behavior | Decreases phenotype | PMID:26108271; PMID:31351385 |
| GO:0042221 | Response to chemical | Increases phenotype | PMID:34428494 |
| GO:0042448 | Progesterone metabolic process | Affects phenotype | PMID:34597818 |
| GO:0042554 | Superoxide anion generation | Affects phenotype | PMID:34793900 |
| GO:0042593 | Glucose homeostasis | Decreases phenotype | PMID:29526571; PMID:38285958 |
| GO:0042632 | Cholesterol homeostasis | Decreases phenotype | PMID:35739755; PMID:38285958 |
| GO:0042701 | Progesterone secretion | Affects phenotype | PMID:30310660; PMID:33316053 |
| GO:0042756 | Drinking behavior | Affects phenotype | PMID:31979393 |
| GO:0042866 | Pyruvate biosynthetic process | Decreases phenotype | PMID:38285958 |
| GO:0043030 | Regulation of macrophage activation | Affects phenotype | PMID:35378083 |
| GO:0043065 | Positive regulation of apoptotic process | Affects phenotype | PMID:26804720; PMID:32810643; PMID:33091774; PMID:33254669; PMID:33511402; PMID:35739755; PMID:37364641; PMID:39151608 |
| GO:0043197 | Dendritic spine | Increases phenotype | PMID:35278568 |
| GO:0043525 | Positive regulation of neuron apoptotic process | Increases phenotype | PMID:33336902 |
| GO:0044029 | Hypomethylation of cpg island | Increases phenotype | PMID:30952838 |
| GO:0044237 | Cellular metabolic process | Increases phenotype | PMID:27581038; PMID:28415704; PMID:30952838; PMID:36375677; PMID:36708983; PMID:36828243 |
| GO:0044319 | Wound healing, spreading of cells | Affects phenotype | PMID:34902519; PMID:38944327 |
| GO:0044849 | Estrous cycle | Affects phenotype | PMID:36929940 |
| GO:0045429 | Positive regulation of nitric oxide biosynthetic process | Increases phenotype | PMID:36089060 |
| GO:0045444 | Fat cell differentiation | Increases phenotype | PMID:24155963; PMID:29991372 |
| GO:0045542 | Positive regulation of cholesterol biosynthetic process | Increases phenotype | PMID:33167028 |
| GO:0045723 | Positive regulation of fatty acid biosynthetic process | Increases phenotype | PMID:33167028 |
| GO:0046034 | Atp metabolic process | Affects phenotype | PMID:28486587; PMID:33711355 |
| GO:0046209 | Nitric oxide metabolic process | Affects phenotype | PMID:34902519; PMID:34902519; PMID:38944327; PMID:38944327 |
| GO:0046326 | Positive regulation of glucose import | Decreases phenotype | PMID:29526571 |
| GO:0046449 | Creatinine metabolic process | Affects phenotype | PMID:32860865; PMID:33729022 |
| GO:0046621 | Negative regulation of organ growth | Increases phenotype | PMID:33086118 |
| GO:0046622 | Positive regulation of organ growth | Increases phenotype | PMID:32518293 |
| GO:0046627 | Negative regulation of insulin receptor signaling pathway | Increases phenotype | PMID:29526571 |
| GO:0046676 | Negative regulation of insulin secretion | Increases phenotype | PMID:29526571; PMID:32810643 |
| GO:0046881 | Positive regulation of follicle-stimulating hormone secretion | Increases phenotype | PMID:37364641 |
| GO:0048168 | Regulation of neuronal synaptic plasticity | Decreases phenotype | PMID:31841868 |
| GO:0048240 | Sperm capacitation | Increases phenotype | PMID:33711355 |
| GO:0048246 | Macrophage chemotaxis | Increases phenotype | PMID:40323316 |
| GO:0048599 | Oocyte development | Decreases phenotype | PMID:28013214 |
| GO:0048745 | Smooth muscle tissue development | Affects phenotype | PMID:35690178 |
| GO:0048808 | Male genitalia morphogenesis | Decreases phenotype | PMID:20002220; PMID:35642937 |
| GO:0050671 | Positive regulation of lymphocyte proliferation | Increases phenotype | PMID:38285958 |
| GO:0050679 | Positive regulation of epithelial cell proliferation | Increases phenotype | PMID:40323316 |
| GO:0050729 | Positive regulation of inflammatory response | Increases phenotype | PMID:31199487; PMID:33254669; PMID:36592837; PMID:38157815 |
| GO:0050996 | Positive regulation of lipid catabolic process | Increases phenotype | PMID:32446102; PMID:33254669; PMID:37505531; PMID:38285958 |
| GO:0055072 | Iron ion homeostasis | Affects phenotype | PMID:39631539 |
| GO:0055074 | Calcium ion homeostasis | Affects phenotype | PMID:30056177 |
| GO:0055075 | Potassium ion homeostasis | Affects phenotype | PMID:39631539 |
| GO:0060011 | Sertoli cell proliferation | Increases phenotype | PMID:32738922 |
| GO:0060135 | Maternal process involved in female pregnancy | Affects phenotype | PMID:32860865 |
| GO:0060305 | Regulation of cell diameter | Affects phenotype | PMID:37021957 |
| GO:0060326 | Cell chemotaxis | Increases phenotype | PMID:35397443 |
| GO:0060376 | Positive regulation of mast cell differentiation | Increases phenotype | PMID:37021957 |
| GO:0060512 | Prostate gland morphogenesis | Decreases phenotype | PMID:20002220; PMID:28341571; PMID:31199487 |
| GO:0060618 | Nipple development | Affects phenotype | PMID:37788136 |
| GO:0060948 | Cardiac vascular smooth muscle cell development | Affects phenotype | PMID:35926758 |
| GO:0061000 | Negative regulation of dendritic spine development | Increases phenotype | PMID:35278568 |
| GO:0061045 | Negative regulation of wound healing | Increases phenotype | PMID:38184977 |
| GO:0061069 | Male urethra development | Affects phenotype | PMID:35690178 |
| GO:0061107 | Seminal vesicle development | Decreases phenotype | PMID:30802670 |
| GO:0061179 | Negative regulation of insulin secretion involved in cellular response to glucose stimulus | Increases phenotype | PMID:33091774 |
| GO:0061370 | Testosterone biosynthetic process | Decreases phenotype | PMID:24753613; PMID:26706031; PMID:28295950; PMID:30053495; PMID:32525071; PMID:33331133; PMID:33331133; PMID:34280466; PMID:36602389; PMID:33331133; PMID:36602389; PMID:33983380; PMID:34280466; PMID:34597818; PMID:35690178 |
| GO:0061458 | Reproductive system development | Decreases phenotype | PMID:37788136 |
| GO:0061516 | Monocyte proliferation | Increases phenotype | PMID:38285958 |
| GO:0061628 | H3k27me3 modified histone binding | Increases phenotype | PMID:24753613 |
| GO:0061682 | Seminal vesicle morphogenesis | Decreases phenotype | PMID:20002220 |
| GO:0061739 | Protein lipidation involved in autophagosome assembly | Increases phenotype | PMID:31568847 |
| GO:0061827 | Sperm head | Affects phenotype | PMID:36215882 |
| GO:0061890 | Positive regulation of astrocyte activation | Increases phenotype | PMID:35278568 |
| GO:0070328 | Triglyceride homeostasis | Decreases phenotype | PMID:35739755; PMID:38285958 |
| GO:0070665 | Positive regulation of leukocyte proliferation | Increases phenotype | PMID:38285958 |
| GO:0070994 | Detection of oxidative stress | Increases phenotype | PMID:33729022; PMID:34793900; PMID:36114491; PMID:37277016 |
| GO:0072089 | Stem cell proliferation | Decreases phenotype | PMID:24753613 |
| GO:0072520 | Seminiferous tubule development | Decreases phenotype | PMID:29029336; PMID:30802670; PMID:37364641 |
| GO:0072593 | Reactive oxygen species metabolic process | Increases phenotype | PMID:27581038; PMID:28415704; PMID:31712109; PMID:39461407 |
| GO:0072677 | Eosinophil migration | Increases phenotype | PMID:30551395 |
| GO:0090280 | Positive regulation of calcium ion import | Increases phenotype | PMID:38157815 |
| GO:0090326 | Positive regulation of locomotion involved in locomotory behavior | Increases phenotype | PMID:32518293 |
| GO:0090592 | Dna synthesis involved in dna replication | Decreases phenotype | PMID:20650509 |
| GO:0097189 | Apoptotic body | Increases phenotype | PMID:27581038 |
| GO:0097202 | Activation of cysteine-type endopeptidase activity | Increases phenotype | PMID:29029336 |
| GO:0097368 | Establishment of sertoli cell barrier | Decreases phenotype | PMID:34280466 |
| GO:0097531 | Mast cell migration | Increases phenotype | PMID:30551395 |
| GO:0097722 | Sperm motility | Decreases phenotype | PMID:28295950; PMID:28295950; PMID:30952838; PMID:30802670; PMID:30934153; PMID:30952838; PMID:33331133; PMID:33331133; PMID:34280466; PMID:33711355; PMID:36215882; PMID:36602389 |
| GO:0098532 | Histone h3-k27 trimethylation | Increases phenotype | PMID:24753613 |
| GO:0098739 | Import across plasma membrane | Increases phenotype | PMID:36708983 |
| GO:0098743 | Cell aggregation | Increases phenotype | PMID:28528174; PMID:33086118; PMID:32525071 |
| GO:0106109 | Positive regulation of (r)-mevalonic acid biosynthetic process | Increases phenotype | PMID:33167028 |
| GO:0120331 | Endothelial tube formation | Increases phenotype | PMID:36089060 |
| GO:0140013 | Meiotic nuclear division | Decreases phenotype | PMID:21868749 |
| GO:0140042 | Lipid droplet formation | Increases phenotype | PMID:30350139; PMID:32417575; PMID:33508418 |
| GO:0140131 | Positive regulation of lymphocyte chemotaxis | Increases phenotype | PMID:29526571 |
| GO:0140354 | Lipid import into cell | Increases phenotype | PMID:35739755 |
| GO:0140639 | Positive regulation of pyroptosis | Increases phenotype | PMID:36592837 |
| GO:0160024 | Leydig cell proliferation | Decreases phenotype | PMID:28611354; PMID:38769170 |
| GO:1900015 | Regulation of cytokine production involved in inflammatory response | Affects phenotype | PMID:38954831 |
| GO:1900017 | Positive regulation of cytokine production involved in inflammatory response | Increases phenotype | PMID:40323316 |
| GO:1901318 | Negative regulation of flagellated sperm motility | Increases phenotype | PMID:17003688; PMID:33086118 |
| GO:1901670 | Negative regulation of superoxide dismutase activity | Increases phenotype | PMID:33120273; PMID:33254669; PMID:33348264 |
| GO:1901671 | Positive regulation of superoxide dismutase activity | Decreases phenotype | PMID:25172463 |
| GO:1901687 | Glutathione derivative biosynthetic process | Increases phenotype | PMID:25172463 |
| GO:1902553 | Positive regulation of catalase activity | Increases phenotype | PMID:25172463 |
| GO:1902884 | Positive regulation of response to oxidative stress | Increases phenotype | PMID:33120273; PMID:33348264; PMID:35739755 |
| GO:1903047 | Mitotic cell cycle process | Affects phenotype | PMID:28415704; PMID:36828243 |
| GO:1903284 | Positive regulation of glutathione peroxidase activity | Decreases phenotype | PMID:25172463 |
| GO:1903409 | Reactive oxygen species biosynthetic process | Increases phenotype | PMID:28295950; PMID:30776390; PMID:30910607 |
| GO:1903428 | Positive regulation of reactive oxygen species biosynthetic process | Increases phenotype | PMID:30453174; PMID:31568847; PMID:32028152; PMID:33091774; PMID:33120273; PMID:33254669; PMID:38285958 |
| GO:1903787 | Negative regulation of glutathione biosynthetic process | Increases phenotype | PMID:32446102; PMID:33254669; PMID:37505531; PMID:37967788 |
| GO:1904177 | Regulation of adipose tissue development | Affects phenotype | PMID:37021957 |
| GO:1904598 | Positive regulation of connective tissue replacement involved in inflammatory response wound healing | Increases phenotype | PMID:35739755 |
| GO:1905037 | Autophagosome organization | Increases phenotype | PMID:37277016 |
| GO:1905053 | Positive regulation of base-excision repair | Increases phenotype | PMID:33120273 |
| GO:1905458 | Positive regulation of lymphoid progenitor cell differentiation | Increases phenotype | PMID:38157815 |
| GO:1905867 | Epididymis development | Affects phenotype | PMID:30802670 |
| GO:1905952 | Regulation of lipid localization | Decreases phenotype | PMID:40221850 |
| GO:1990428 | Mirna transport | Affects phenotype | PMID:30481674 |
| GO:2000134 | Negative regulation of g1/s transition of mitotic cell cycle | Increases phenotype | PMID:25369342 |
| GO:2000184 | Positive regulation of progesterone biosynthetic process | Increases phenotype | PMID:37552060 |
| GO:2000225 | Negative regulation of testosterone biosynthetic process | Increases phenotype | PMID:29029336; PMID:33086118; PMID:35739735; PMID:37788136 |
| GO:2000354 | Regulation of ovarian follicle development | Affects phenotype | PMID:31318015 |
| GO:2000355 | Negative regulation of ovarian follicle development | Increases phenotype | PMID:36993736; PMID:37505531 |
| GO:2000391 | Positive regulation of neutrophil extravasation | Increases phenotype | PMID:32446102; PMID:37967788 |
| GO:2000403 | Positive regulation of lymphocyte migration | Increases phenotype | PMID:32446102 |
| GO:2000409 | Positive regulation of t cell extravasation | Increases phenotype | PMID:37967788 |
| GO:2000421 | Positive regulation of eosinophil extravasation | Increases phenotype | PMID:32446102; PMID:33254669; PMID:37967788; PMID:38157815 |
| GO:2000609 | Regulation of thyroid hormone generation | Affects phenotype | PMID:29385629 |
| GO:2000844 | Negative regulation of testosterone secretion | Increases phenotype | PMID:29029336; PMID:32497820; PMID:37839492; PMID:39947446 |
| GO:2000845 | Positive regulation of testosterone secretion | Affects phenotype | PMID:26745512; PMID:26948521; PMID:28341571; PMID:28919491; PMID:37364641 |
| GO:2000853 | Negative regulation of corticosterone secretion | Increases phenotype | PMID:34864161 |
| GO:2000865 | Negative regulation of estradiol secretion | Increases phenotype | PMID:29029336; PMID:37839492 |
| GO:2000866 | Positive regulation of estradiol secretion | Affects phenotype | PMID:28104404; PMID:37364641 |
| GO:2000871 | Negative regulation of progesterone secretion | Increases phenotype | PMID:35028925 |
| GO:2000872 | Positive regulation of progesterone secretion | Decreases phenotype | PMID:28104404 |
| GO:2001295 | Malonyl-coa biosynthetic process | Increases phenotype | PMID:33167028 |
We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.