Methoxychlor


Curated chemical-phenotype interactions from CTD
GO IDGO nameInteraction typeReference
GO:0002638 Negative regulation of immunoglobulin production Increases phenotype PMID:24188624
GO:0002639 Positive regulation of immunoglobulin production Increases phenotype PMID:24935097
GO:0002693 Positive regulation of cellular extravasation Increases phenotype PMID:30017638
GO:0002866 Positive regulation of acute inflammatory response to antigenic stimulus Increases phenotype PMID:30017638
GO:0006702 Androgen biosynthetic process Decreases phenotype PMID:27663972
GO:0006805 Xenobiotic metabolic process Increases phenotype PMID:29162470
GO:0007614 Short-term memory Increases phenotype PMID:24982620
GO:0008219 Cell death Increases phenotype PMID:26961610
GO:0008283 Cell population proliferation Affects phenotype PMID:24806340; PMID:24832206; PMID:24835555; PMID:27663972; PMID:28855101
GO:0008284 Positive regulation of cell population proliferation Increases phenotype PMID:28426875; PMID:35307500
GO:0008285 Negative regulation of cell population proliferation Increases phenotype PMID:29149346; PMID:31549662
GO:0008584 Male gonad development Affects phenotype PMID:25048109
GO:0016049 Cell growth Decreases phenotype PMID:36277366
GO:0031324 Negative regulation of cellular metabolic process Increases phenotype PMID:35413382
GO:0031589 Cell-substrate adhesion Decreases phenotype PMID:32466334
GO:0031959 Mineralocorticoid receptor signaling pathway Increases phenotype PMID:29149346
GO:0033148 Positive regulation of intracellular estrogen receptor signaling pathway Increases phenotype PMID:26139245; PMID:27473340
GO:0035847 Uterine epithelium development Increases phenotype PMID:27473340
GO:0035938 Estradiol secretion Increases phenotype PMID:30817981
GO:0040029 Epigenetic regulation of gene expression Affects phenotype PMID:25057798
GO:0044237 Cellular metabolic process Decreases phenotype PMID:36277366
GO:0045931 Positive regulation of mitotic cell cycle Increases phenotype PMID:35307500
GO:0046622 Positive regulation of organ growth Increases phenotype PMID:27473340
GO:0050769 Positive regulation of neurogenesis Increases phenotype PMID:24982620
GO:0060326 Cell chemotaxis Increases phenotype PMID:32466334
GO:0061370 Testosterone biosynthetic process Decreases phenotype PMID:27663972
GO:0070374 Positive regulation of erk1 and erk2 cascade Increases phenotype PMID:27413106
GO:1900017 Positive regulation of cytokine production involved in inflammatory response Increases phenotype PMID:24935097
GO:1900745 Positive regulation of p38mapk cascade Increases phenotype PMID:27413106
GO:1903047 Mitotic cell cycle process Affects phenotype PMID:32466334
GO:1903365 Regulation of fear response Affects phenotype PMID:24982620
GO:1903709 Uterine gland development Increases phenotype PMID:27473340
GO:1903753 Negative regulation of p38mapk cascade Increases phenotype PMID:35413382
GO:1990349 Gap junction-mediated intercellular transport Decreases phenotype PMID:27413106; PMID:35413382
GO:2000529 Positive regulation of myeloid dendritic cell chemotaxis Increases phenotype PMID:30017638
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We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.