| GO ID | GO name | Interaction type | Reference |
|---|---|---|---|
| GO:0006144 | Purine nucleobase metabolic process | Increases phenotype | PMID:30487447 |
| GO:0006541 | Glutamine metabolic process | Increases phenotype | PMID:30487447 |
| GO:0006805 | Xenobiotic metabolic process | Increases phenotype | PMID:29162470 |
| GO:0006909 | Phagocytosis | Decreases phenotype | PMID:26133781 |
| GO:0007283 | Spermatogenesis | Decreases phenotype | PMID:29029336 |
| GO:0007566 | Embryo implantation | Decreases phenotype | PMID:30061528 |
| GO:0008210 | Estrogen metabolic process | Affects phenotype | PMID:28611354 |
| GO:0008283 | Cell population proliferation | Increases phenotype | PMID:23626723; PMID:24213142; PMID:24684733 |
| GO:0008284 | Positive regulation of cell population proliferation | Increases phenotype | PMID:29783106; PMID:29783106; PMID:35307500 |
| GO:0008584 | Male gonad development | Affects phenotype | PMID:28611354 |
| GO:0030263 | Apoptotic chromosome condensation | Increases phenotype | PMID:28611354; PMID:29029336 |
| GO:0031589 | Cell-substrate adhesion | Decreases phenotype | PMID:32466334 |
| GO:0042816 | Vitamin b6 metabolic process | Increases phenotype | PMID:30487447 |
| GO:0044319 | Wound healing, spreading of cells | Increases phenotype | PMID:27145024 |
| GO:0045931 | Positive regulation of mitotic cell cycle | Increases phenotype | PMID:35307500 |
| GO:0046087 | Cytidine metabolic process | Increases phenotype | PMID:30487447 |
| GO:0046108 | Uridine metabolic process | Increases phenotype | PMID:30487447 |
| GO:0046621 | Negative regulation of organ growth | Increases phenotype | PMID:30487447 |
| GO:0060326 | Cell chemotaxis | Increases phenotype | PMID:32466334 |
| GO:0070471 | Uterine smooth muscle contraction | Decreases phenotype | PMID:23664861 |
| GO:0072520 | Seminiferous tubule development | Decreases phenotype | PMID:29029336 |
| GO:0097202 | Activation of cysteine-type endopeptidase activity | Increases phenotype | PMID:29029336 |
| GO:0160024 | Leydig cell proliferation | Affects phenotype | PMID:28611354 |
| GO:1903047 | Mitotic cell cycle process | Affects phenotype | PMID:32466334 |
| GO:1990403 | Embryonic brain development | Decreases phenotype | PMID:40347494 |
| GO:2000865 | Negative regulation of estradiol secretion | Increases phenotype | PMID:29029336 |
We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.