o,p'-DDT


Curated chemical-phenotype interactions from CTD
GO IDGO nameInteraction typeReference
GO:0004364 Glutathione transferase activity Decreases phenotype PMID:35122929
GO:0006304 Dna modification Increases phenotype PMID:35122929
GO:0006306 Dna methylation Affects phenotype PMID:28263910; PMID:33865946
GO:0006606 Protein import into nucleus Affects phenotype PMID:34167450
GO:0006749 Glutathione metabolic process Increases phenotype PMID:35122929
GO:0008283 Cell population proliferation Increases phenotype PMID:17599374; PMID:23913582; PMID:7588483; PMID:8968093
GO:0008284 Positive regulation of cell population proliferation Increases phenotype PMID:28531659
GO:0008285 Negative regulation of cell population proliferation Increases phenotype PMID:29149346
GO:0010917 Negative regulation of mitochondrial membrane potential Increases phenotype PMID:35122929
GO:0016477 Cell migration Affects phenotype PMID:23913582
GO:0030154 Cell differentiation Increases phenotype PMID:7588483
GO:0031324 Negative regulation of cellular metabolic process Increases phenotype PMID:35122929
GO:0031959 Mineralocorticoid receptor signaling pathway Increases phenotype PMID:29149346
GO:0033148 Positive regulation of intracellular estrogen receptor signaling pathway Increases phenotype PMID:26022396
GO:0034109 Homotypic cell-cell adhesion Decreases phenotype PMID:26225806
GO:0043065 Positive regulation of apoptotic process Increases phenotype PMID:35122929
GO:0043433 Negative regulation of dna-binding transcription factor activity Increases phenotype PMID:26022396
GO:0045919 Positive regulation of cytolysis Increases phenotype PMID:35122929
GO:0048589 Developmental growth Decreases phenotype PMID:25095280
GO:0050847 Progesterone receptor signaling pathway Decreases phenotype PMID:26022396
GO:0050890 Cognition Decreases phenotype PMID:16818570
GO:0051091 Positive regulation of dna-binding transcription factor activity Increases phenotype PMID:26022396
GO:0051348 Negative regulation of transferase activity Affects phenotype PMID:35122929
GO:0060322 Head development Decreases phenotype PMID:25095280
GO:0060326 Cell chemotaxis Increases phenotype PMID:26225806
GO:0060612 Adipose tissue development Increases phenotype PMID:31746186
GO:0097237 Cellular response to toxic substance Decreases phenotype PMID:35122929
GO:1900181 Negative regulation of protein localization to nucleus Increases phenotype PMID:35122929
GO:1901142 Insulin metabolic process Affects phenotype PMID:31746186
GO:1901670 Negative regulation of superoxide dismutase activity Increases phenotype PMID:35122929
GO:1903283 Negative regulation of glutathione peroxidase activity Increases phenotype PMID:35122929
GO:1903428 Positive regulation of reactive oxygen species biosynthetic process Increases phenotype PMID:35122929
GO:2000610 Negative regulation of thyroid hormone generation Increases phenotype PMID:31284115
DISCLAIMER

We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.