| Literature identifier | Study type | Test dosage | Effective dosage | Endocrine-mediated endpoints | Systems-level perturbations |
|---|---|---|---|---|---|
| PMID:3803340 | IVR | 1 mg/L | - | No significant effects observed | - |
| IVR | 100 mg/L | 100 mg/L | Decrease in T4 levels | Metabolic endocrine-mediated perturbations | |
| IVR | 100 mg/L | 100 mg/L | Affects sperm motility | Reproductive endocrine-mediated perturbations | |
| IVR | 10 mg/L | - | No significant effects observed | - | |
| IVR | 100 mg/L | 100 mg/L | Decrease in T3 levels | Metabolic endocrine-mediated perturbations | |
| IVR | 100 mg/L | 100 mg/L | Abnormal sperm morphology | Reproductive endocrine-mediated perturbations | |
| IVR | 500 mg/L | 500 mg/L | Decrease in T4 levels | Metabolic endocrine-mediated perturbations | |
| IVR | 500 mg/L | 500 mg/L | Decrease in T3 levels | Metabolic endocrine-mediated perturbations | |
| IVR | 500 mg/L | 500 mg/L | Abnormal sperm morphology | Reproductive endocrine-mediated perturbations | |
| IVR | 500 mg/L | 500 mg/L | Affects sperm motility | Reproductive endocrine-mediated perturbations | |
| PMID:7151764 | IVR | 200 mg/kg | 200 mg/kg | Alteration in vaginal morphology | Reproductive endocrine-mediated perturbations |
| IVR | 200 mg/kg | 200 mg/kg | Causes vaginal bleeding | Reproductive endocrine-mediated perturbations | |
| IVR | 10 mg/kg | 10 mg/kg | Affects litter size | Reproductive endocrine-mediated perturbations | |
| IVR | 0.1 % | - | No significant effects observed | - | |
| IVR | 0.5 % | - | No significant effects observed | - | |
| IVR | 50 mg/kg | 50 mg/kg | Alteration in vaginal morphology | Reproductive endocrine-mediated perturbations | |
| IVR | 50 mg/kg | 50 mg/kg | Causes vaginal bleeding | Reproductive endocrine-mediated perturbations | |
| IVR | 20 mg/kg | 20 mg/kg | Affects litter size | Reproductive endocrine-mediated perturbations | |
| IVR | 20 mg/kg | 20 mg/kg | Causes vaginal bleeding | Reproductive endocrine-mediated perturbations | |
| IVR | 20 mg/kg | 20 mg/kg | Alteration in vaginal morphology | Reproductive endocrine-mediated perturbations | |
| IVR | 2 % | 2 % | Changes in haemocrit values | Immunological endocrine-mediated perturbations | |
| IVR | 2 % | 2 % | Affects litter size | Reproductive endocrine-mediated perturbations |
We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.