| Assay Name | Tissue | Organism | Target Gene ID | Target HGNC Symbol | Response | AC50 Value |
|---|
| CCTE_GLTED_hTBG | | Human | 6906 | SERPINA7 | Loss | 1.64 μM |
| CCTE_GLTED_hTTR_0.125uM | | Human | 7276 | TTR | Loss | 1.74 μM |
| CCTE_Deisenroth_DEVTOX-GLR_legacy_Sox17 | Pluripotent stem cell | Human | 64321 | SOX17 | Activatory | |
| CCTE_Deisenroth_DEVTOX-GLR_legacy_Sox2 | Pluripotent stem cell | Human | 6657 | SOX2 | Gain | |
| CCTE_Deisenroth_DEVTOX-GLR_legacy_Bra | Pluripotent stem cell | Human | 6862 | TBXT | Gain | |
| CCTE_Deisenroth_DEVTOX-GLR_Endo_SOX17 | Pluripotent stem cell | Human | 64321 | SOX17 | Inhibitory | |
| CCTE_Deisenroth_DEVTOX-GLR_Endo_SOX2 | Pluripotent stem cell | Human | 6657 | SOX2 | Gain | |
| CCTE_Deisenroth_DEVTOX-GLR_Endo_BRA | Pluripotent stem cell | Human | 6862 | TBXT | Gain | |
| CCTE_Deisenroth_DEVTOX-GLR_Pluri_SOX17 | Pluripotent stem cell | Human | 64321 | SOX17 | Gain | |
| CCTE_Deisenroth_DEVTOX-GLR_Pluri_SOX2 | Pluripotent stem cell | Human | 6657 | SOX2 | Inhibitory | |
| CCTE_Deisenroth_DEVTOX-GLR_Pluri_BRA | Pluripotent stem cell | Human | 6862 | TBXT | Gain | |
| NVS_ADME_hCYP3A4 | | Human | 1576 | CYP3A4 | Loss | 10.0 μM |
| NVS_TR_hDAT | | Human | 6531 | SLC6A3 | Loss | 6.86 μM |
| ATG_DR5_RAR_CIS | Liver | Human | 5914|5915|5916 | RARA|RARB|RARG | Inhibitory | 36.63 μM |
| ATG_PPRE_CIS | Liver | Human | 5465|5467|5468 | PPARA|PPARD|PPARG | Inhibitory | 12.47 μM |
| ATG_PPARg_TRANS | Liver | Human | 5468 | PPARG | Gain | 6.85 μM |
| BSK_BE3C_MMP1 | Lung | Human | 4312 | MMP1 | Inhibitory | 7.79 μM |
| BSK_CASM3C_IL6 | Vascular | Human | 3569 | IL6 | Inhibitory | 0.34 μM |
| BSK_hDFCGF_CollagenIII | Skin | Human | 1281 | COL3A1 | Inhibitory | 20.0 μM |
| BSK_LPS_PGE2 | Vascular | Human | 5732 | PTGER2 | Inhibitory | 0.15 μM |
| TOX21_PPARg_BLA_Agonist_ratio | Kidney | Human | 5468 | PPARG | Gain | 5.16 μM |
| TOX21_p450_CYP2C9_Antagonist | | Human | 1559 | CYP2C9 | Loss | 10.49 μM |
| TOX21_AR_BLA_Antagonist_ratio | Kidney | Human | 367 | AR | Loss | 44.09 μM |
| TOX21_PPARg_BLA_Agonist_ratio | Kidney | Human | 5468 | PPARG | Gain | 2.93 μM |
| TOX21_ERR_LUC_Antagonist | Kidney | Human | 2101 | ESRRA | Loss | 34.85 μM |
| TOX21_PGC_ERR_LUC_Antagonist | Kidney | Human | 2101 | ESRRA | Loss | 39.07 μM |
| TOX21_ERb_BLA_Antagonist_ratio | Kidney | Human | 2100 | ESR2 | Loss | 25.86 μM |
| TOX21_PR_BLA_Antagonist_ratio | Kidney | Human | 5241 | PGR | Loss | 54.88 μM |
| TOX21_p450_CYP3A4_Antagonist | | Human | 1576 | CYP3A4 | Loss | 39.77 μM |
| TOX21_p450_CYP2D6_Antagonist | | Human | 1565 | CYP2D6 | Loss | 27.07 μM |
| TOX21_p450_CYP2C9_Antagonist | | Human | 1559 | CYP2C9 | Loss | 13.36 μM |
| TOX21_p450_CYP1A2_Antagonist | | Human | 1544 | CYP1A2 | Loss | 70.66 μM |
| TOX21_PPARg_BLA_Agonist_ratio | Kidney | Human | 5468 | PPARG | Gain | 2.47 μM |
| TOX21_ERR_LUC_Antagonist | Kidney | Human | 2101 | ESRRA | Loss | 46.08 μM |
| TOX21_ERb_BLA_Antagonist_ratio | Kidney | Human | 2100 | ESR2 | Loss | 46.08 μM |
| TOX21_p450_CYP2C9_Antagonist | | Human | 1559 | CYP2C9 | Loss | 13.87 μM |
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