Perfluorooctane sulfonic acid


Curated chemical-disease associations from CTD
Disease IDDisease nameReference
MESH:C535464 Conotruncal cardiac defects PMID:33882431
MESH:D000013 Congenital Abnormalities PMID:20878907; PMID:29803886
MESH:D000014 Abnormalities, Drug-Induced PMID:29458080
MESH:D000015 Abnormalities, Multiple PMID:24667235; PMID:39104825
MESH:D000067877 Autism Spectrum Disorder PMID:29298162
MESH:D000075902 Clinical Deterioration PMID:34990082
MESH:D001249 Asthma PMID:32485600
MESH:D001284 Atrophy PMID:19464571; PMID:21571052
MESH:D001289 Attention Deficit Disorder with Hyperactivity PMID:20551004
MESH:D001523 Mental Disorders PMID:18063051
MESH:D001724 Birth Weight PMID:32980420; PMID:36920051
MESH:D001835 Body Weight PMID:33208860; PMID:34464680
MESH:D001927 Brain Diseases PMID:18063051
MESH:D001943 Breast Neoplasms PMID:24420840; PMID:28610584; PMID:32580117
MESH:D002471 Cell Transformation, Neoplastic PMID:29063134
MESH:D002972 Cleft Palate PMID:19041924
MESH:D003072 Cognition Disorders PMID:37952603
MESH:D003324 Coronary Artery Disease PMID:38758093
MESH:D003643 Death PMID:20686339
MESH:D003924 Diabetes Mellitus, Type 2 PMID:29498927; PMID:33993001
MESH:D004485 Eczema PMID:32717646
MESH:D005128 Eye Diseases PMID:32059142
MESH:D005234 Fatty Liver PMID:21467747; PMID:21705711; PMID:27413108; PMID:28973659; PMID:32979393; PMID:35999056; PMID:39894534
MESH:D005313 Fetal Death PMID:20570370
MESH:D005355 Fibrosis PMID:28973641
MESH:D005909 Glioblastoma PMID:17162496
MESH:D006130 Growth Disorders PMID:17504768
MESH:D006505 Hepatitis PMID:23237827
MESH:D006529 Hepatomegaly PMID:12773772; PMID:18252804; PMID:18923995; PMID:19464571; PMID:19540903; PMID:19900501; PMID:21705711; PMID:22245121; PMID:23237827; PMID:25543169; PMID:25949234; PMID:26844784; PMID:27153767; PMID:32979393; PMID:34464680; PMID:34861291; PMID:34990082; PMID:35999056; PMID:39894534
MESH:D006973 Hypertension PMID:32958007; PMID:32980420
MESH:D006984 Hypertrophy PMID:21467747
MESH:D007154 Immune System Diseases PMID:18252804
MESH:D007248 Infertility, Male PMID:23761298
MESH:D007859 Learning Disabilities PMID:19954077; PMID:25524167
MESH:D007889 Leiomyoma PMID:37224071
MESH:D008103 Liver Cirrhosis PMID:34990082
MESH:D008113 Liver Neoplasms PMID:20143881; PMID:24420840
MESH:D008206 Lymphatic Diseases PMID:21571052
MESH:D008231 Lymphopenia PMID:19540903
MESH:D008569 Memory Disorders PMID:19954077; PMID:25524167
MESH:D008607 Intellectual Disability PMID:29298162
MESH:D009336 Necrosis PMID:23948355
MESH:D009385 Neoplastic Processes PMID:37224071
MESH:D009410 Nerve Degeneration PMID:23948355
MESH:D009461 Neurologic Manifestations PMID:31428778
MESH:D009845 Oligospermia PMID:19590684; PMID:33359577
MESH:D011041 Poisoning PMID:22465071; PMID:23562911
MESH:D011085 Polycystic Ovary Syndrome PMID:37134253
MESH:D011225 Pre-Eclampsia PMID:34637358
MESH:D011297 Prenatal Exposure Delayed Effects PMID:17504768; PMID:18252804; PMID:19909767; PMID:20686339; PMID:22274686; PMID:25524167; PMID:25543169; PMID:25567242; PMID:32353786; PMID:32980420; PMID:33882431; PMID:34500360; PMID:37955688
MESH:D012893 Sleep Wake Disorders PMID:39512894
MESH:D013733 Testicular Diseases PMID:36321694
MESH:D013959 Thyroid Diseases PMID:12773772; PMID:20089479
MESH:D013964 Thyroid Neoplasms PMID:24420840
MESH:D014652 Vascular Diseases PMID:22269386
MESH:D015430 Weight Gain PMID:32959518
MESH:D015431 Weight Loss PMID:19464571; PMID:19483379; PMID:21467747; PMID:32979393; PMID:32980420; PMID:35999056; PMID:37148813
MESH:D016640 Diabetes, Gestational PMID:33984575
MESH:D018248 Adenoma, Liver Cell PMID:22245121; PMID:22266392
MESH:D019465 Craniofacial Abnormalities PMID:32553615
MESH:D020964 Embryo Loss PMID:20878907
MESH:D033461 Hyperuricemia PMID:22003309; PMID:23552989
MESH:D050171 Dyslipidemias PMID:21705711
MESH:D055370 Lung Injury PMID:37955688
MESH:D056486 Chemical and Drug Induced Liver Injury PMID:18996565; PMID:21459123; PMID:22289616; PMID:24420840; PMID:26844784; PMID:34990082; PMID:39894534
MESH:D058186 Acute Kidney Injury PMID:35934180
MESH:D060825 Cognitive Dysfunction PMID:38385684
MESH:D064420 Drug-Related Side Effects and Adverse Reactions PMID:21459123
MESH:D064793 Teratogenesis PMID:23562911
MESH:D066087 Perinatal Death PMID:25543169
MESH:D066126 Cardiotoxicity PMID:28288859

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We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.