Pathway ID | Pathway Name | No. of Genes | NCBI Gene Identifier | Official Symbol |
---|---|---|---|---|
hsa01100 | Metabolic pathways | 30 | 10402, 10728, 1158, 1577, 1591, 1594, 210, 2572, 2876, 29968, 3291, 3906, 4257, 4514, 4843, 52, 5281, 54658, 55790, 5723, 5743, 6480, 6487, 760, 847, 8869, 8877, 8942, 8991, 9588 | ST3GAL6, PTGES3, CKM, CYP3A5, CYP24A1, CYP27B1, ALAD, GAD2, GPX1, PSAT1, HSD11B2, LALBA, MGST1, COX3, NOS2, ACP1, PIGF, UGT1A1, CSGALNACT1, PSPH, PTGS2, ST6GAL1, ST3GAL3, CA2, CAT, ST3GAL5, SPHK1, KYNU, SELENBP1, PRDX6 |
hsa04060 | Cytokine-cytokine receptor interaction | 29 | 10563, 10673, 1442, 1443, 3553, 3554, 3557, 3569, 3570, 3572, 3575, 3576, 3577, 3623, 3624, 3625, 3627, 3976, 3977, 4283, 5617, 6362, 6375, 6387, 7124, 7850, 8743, 92, 93 | CXCL13, TNFSF13B, CSH1, CSH2, IL1B, IL1R1, IL1RN, IL6, IL6R, IL6ST, IL7R, CXCL8, CXCR1, INHA, INHBA, INHBB, CXCL10, LIF, LIFR, CXCL9, PRL, CCL18, XCL1, CXCL12, TNF, IL1R2, TNFSF10, ACVR2A, ACVR2B |
hsa05200 | Pathways in cancer | 26 | 1499, 185, 1956, 2335, 2786, 3280, 3569, 3570, 3572, 3575, 3576, 4257, 4843, 5228, 572, 5743, 596, 6256, 6257, 6258, 6387, 6500, 6774, 7422, 7428, 999 | CTNNB1, AGTR1, EGFR, FN1, GNG4, HES1, IL6, IL6R, IL6ST, IL7R, CXCL8, MGST1, NOS2, PGF, BAD, PTGS2, BCL2, RXRA, RXRB, RXRG, CXCL12, SKP1, STAT3, VEGFA, VHL, CDH1 |
hsa04151 | PI3K-Akt signaling pathway | 25 | 1442, 1443, 1956, 2321, 2335, 2786, 284, 285, 3569, 3570, 3575, 3680, 3690, 3694, 3791, 5228, 5617, 572, 596, 6256, 627, 7097, 7099, 7422, 80310 | CSH1, CSH2, EGFR, FLT1, FN1, GNG4, ANGPT1, ANGPT2, IL6, IL6R, IL7R, ITGA9, ITGB3, ITGB6, KDR, PGF, PRL, BAD, BCL2, RXRA, BDNF, TLR2, TLR4, VEGFA, PDGFD |
hsa04080 | Neuroactive ligand-receptor interaction | 18 | 10203, 1081, 1268, 133, 1394, 1442, 1443, 185, 1901, 2550, 2555, 2892, 3357, 3814, 5340, 5617, 6750, 7349 | CALCRL, CGA, CNR1, ADM, CRHR1, CSH1, CSH2, AGTR1, S1PR1, GABBR1, GABRA2, GRIA3, HTR2B, KISS1, PLG, PRL, SST, UCN |
hsa05022 | Pathways of neurodegeneration | 17 | 11315, 1499, 1767, 2876, 2892, 3553, 3569, 4514, 4843, 572, 5743, 596, 627, 6647, 7124, 847, 9001 | PARK7, CTNNB1, DNAH5, GPX1, GRIA3, IL1B, IL6, COX3, NOS2, BAD, PTGS2, BCL2, BDNF, SOD1, TNF, CAT, HAP1 |
hsa05164 | Influenza A | 15 | 3113, 3119, 3122, 3553, 3569, 3576, 3627, 5340, 64499, 7099, 7124, 7177, 8743, 91543, 9230 | HLA-DPA1, HLA-DQB1, HLA-DRA, IL1B, IL6, CXCL8, CXCL10, PLG, TPSB2, TLR4, TNF, TPSAB1, TNFSF10, RSAD2, RAB11B |
hsa04510 | Focal adhesion | 15 | 1499, 1956, 2321, 2335, 29780, 3680, 3690, 3694, 3791, 5228, 572, 596, 7094, 7422, 80310 | CTNNB1, EGFR, FLT1, FN1, PARVB, ITGA9, ITGB3, ITGB6, KDR, PGF, BAD, BCL2, TLN1, VEGFA, PDGFD |
hsa05323 | Rheumatoid arthritis | 14 | 10673, 2321, 284, 3113, 3119, 3122, 3553, 3569, 3576, 6387, 7097, 7099, 7124, 7422 | TNFSF13B, FLT1, ANGPT1, HLA-DPA1, HLA-DQB1, HLA-DRA, IL1B, IL6, CXCL8, CXCL12, TLR2, TLR4, TNF, VEGFA |
hsa04015 | Rap1 signaling pathway | 14 | 1268, 1499, 1956, 2321, 2533, 284, 285, 3690, 3791, 5228, 7094, 7422, 80310, 999 | CNR1, CTNNB1, EGFR, FLT1, FYB1, ANGPT1, ANGPT2, ITGB3, KDR, PGF, TLN1, VEGFA, PDGFD, CDH1 |
hsa05163 | Human cytomegalovirus infection | 14 | 1499, 1956, 2786, 3553, 3554, 3569, 3570, 3576, 3690, 5743, 6387, 6774, 7124, 7422 | CTNNB1, EGFR, GNG4, IL1B, IL1R1, IL6, IL6R, CXCL8, ITGB3, PTGS2, CXCL12, STAT3, TNF, VEGFA |
hsa05152 | Tuberculosis | 14 | 1594, 3113, 3119, 3122, 3553, 3569, 4843, 572, 596, 7097, 7099, 7124, 7421, 8877 | CYP27B1, HLA-DPA1, HLA-DQB1, HLA-DRA, IL1B, IL6, NOS2, BAD, BCL2, TLR2, TLR4, TNF, VDR, SPHK1 |
hsa05132 | Salmonella infection | 13 | 1499, 27072, 3553, 3569, 3576, 388, 57381, 596, 6500, 7097, 7099, 7124, 8743 | CTNNB1, VPS41, IL1B, IL6, CXCL8, RHOB, RHOJ, BCL2, SKP1, TLR2, TLR4, TNF, TNFSF10 |
hsa04630 | JAK-STAT signaling pathway | 13 | 1442, 1443, 1956, 2273, 3569, 3570, 3572, 3575, 3976, 3977, 5617, 596, 6774 | CSH1, CSH2, EGFR, FHL1, IL6, IL6R, IL6ST, IL7R, LIF, LIFR, PRL, BCL2, STAT3 |
hsa05207 | Chemical carcinogenesis | 13 | 10728, 1956, 4257, 5241, 54658, 572, 596, 6256, 6257, 6258, 6774, 7421, 7422 | PTGES3, EGFR, MGST1, PGR, UGT1A1, BAD, BCL2, RXRA, RXRB, RXRG, STAT3, VDR, VEGFA |
hsa05417 | Lipid and atherosclerosis | 13 | 3553, 3569, 3576, 572, 596, 6256, 6257, 6258, 6774, 7097, 7099, 7124, 8743 | IL1B, IL6, CXCL8, BAD, BCL2, RXRA, RXRB, RXRG, STAT3, TLR2, TLR4, TNF, TNFSF10 |
hsa05418 | Fluid shear stress and atherosclerosis | 13 | 1499, 3553, 3554, 3690, 3791, 4257, 59341, 596, 7124, 7422, 7850, 92, 93 | CTNNB1, IL1B, IL1R1, ITGB3, KDR, MGST1, TRPV4, BCL2, TNF, VEGFA, IL1R2, ACVR2A, ACVR2B |
hsa04010 | MAPK signaling pathway | 13 | 1845, 1956, 2321, 284, 285, 3553, 3554, 3791, 5228, 627, 7124, 7422, 80310 | DUSP3, EGFR, FLT1, ANGPT1, ANGPT2, IL1B, IL1R1, KDR, PGF, BDNF, TNF, VEGFA, PDGFD |
hsa04061 | Viral protein interaction with cytokine and cytokine receptor | 13 | 10563, 3569, 3570, 3572, 3576, 3577, 3627, 4283, 6362, 6375, 6387, 7124, 8743 | CXCL13, IL6, IL6R, IL6ST, CXCL8, CXCR1, CXCL10, CXCL9, CCL18, XCL1, CXCL12, TNF, TNFSF10 |
hsa04066 | HIF-1 signaling pathway | 12 | 1956, 2321, 284, 285, 3569, 3570, 4843, 596, 6774, 7099, 7422, 7428 | EGFR, FLT1, ANGPT1, ANGPT2, IL6, IL6R, NOS2, BCL2, STAT3, TLR4, VEGFA, VHL |
hsa05205 | Proteoglycans in cancer | 12 | 1499, 1956, 2335, 2719, 3690, 3791, 4060, 6774, 7097, 7099, 7124, 7422 | CTNNB1, EGFR, FN1, GPC3, ITGB3, KDR, LUM, STAT3, TLR2, TLR4, TNF, VEGFA |
hsa05171 | Coronavirus disease | 12 | 185, 1956, 3553, 3569, 3570, 3572, 3576, 3627, 6774, 7097, 7099, 7124 | AGTR1, EGFR, IL1B, IL6, IL6R, IL6ST, CXCL8, CXCL10, STAT3, TLR2, TLR4, TNF |
hsa04659 | Th17 cell differentiation | 12 | 3113, 3119, 3122, 3553, 3554, 3569, 3570, 3572, 6256, 6257, 6258, 6774 | HLA-DPA1, HLA-DQB1, HLA-DRA, IL1B, IL1R1, IL6, IL6R, IL6ST, RXRA, RXRB, RXRG, STAT3 |
hsa04014 | Ras signaling pathway | 11 | 1956, 2321, 2786, 284, 285, 3791, 5228, 572, 627, 7422, 80310 | EGFR, FLT1, GNG4, ANGPT1, ANGPT2, KDR, PGF, BAD, BDNF, VEGFA, PDGFD |
hsa04640 | Hematopoietic cell lineage | 11 | 3113, 3119, 3122, 3553, 3554, 3569, 3570, 3575, 3690, 7124, 7850 | HLA-DPA1, HLA-DQB1, HLA-DRA, IL1B, IL1R1, IL6, IL6R, IL7R, ITGB3, TNF, IL1R2 |
hsa04062 | Chemokine signaling pathway | 11 | 10563, 2786, 3576, 3577, 3627, 4283, 572, 6362, 6375, 6387, 6774 | CXCL13, GNG4, CXCL8, CXCR1, CXCL10, CXCL9, BAD, CCL18, XCL1, CXCL12, STAT3 |
hsa05165 | Human papillomavirus infection | 11 | 1499, 1956, 2335, 3280, 3680, 3690, 3694, 572, 5743, 7124, 7422 | CTNNB1, EGFR, FN1, HES1, ITGA9, ITGB3, ITGB6, BAD, PTGS2, TNF, VEGFA |
hsa05202 | Transcriptional misregulation in cancer | 11 | 2115, 2321, 2892, 3486, 3569, 3576, 6256, 6257, 6258, 7850, 8842 | ETV1, FLT1, GRIA3, IGFBP3, IL6, CXCL8, RXRA, RXRB, RXRG, IL1R2, PROM1 |
hsa05169 | Epstein-Barr virus infection | 10 | 3113, 3119, 3122, 3280, 3569, 3627, 596, 6774, 7097, 7124 | HLA-DPA1, HLA-DQB1, HLA-DRA, HES1, IL6, CXCL10, BCL2, STAT3, TLR2, TNF |
hsa05206 | MicroRNAs in cancer | 10 | 1591, 1956, 3690, 406997, 442898, 5743, 596, 6774, 7168, 7422 | CYP24A1, EGFR, ITGB3, MIR215, MIR324, PTGS2, BCL2, STAT3, TPM1, VEGFA |
hsa05145 | Toxoplasmosis | 10 | 3113, 3119, 3122, 4843, 572, 596, 6774, 7097, 7099, 7124 | HLA-DPA1, HLA-DQB1, HLA-DRA, NOS2, BAD, BCL2, STAT3, TLR2, TLR4, TNF |
hsa05166 | Human T-cell leukemia virus 1 infection | 10 | 3113, 3119, 3122, 3554, 3569, 4316, 7094, 7124, 7850, 991 | HLA-DPA1, HLA-DQB1, HLA-DRA, IL1R1, IL6, MMP7, TLN1, TNF, IL1R2, CDC20 |
hsa04350 | TGF-beta signaling pathway | 10 | 10468, 2331, 3624, 3625, 4052, 6500, 7124, 92, 9241, 93 | FST, FMOD, INHBA, INHBB, LTBP1, SKP1, TNF, ACVR2A, NOG, ACVR2B |
hsa05168 | Herpes simplex virus 1 infection | 10 | 3113, 3119, 3122, 3553, 3569, 3690, 572, 596, 7097, 7124 | HLA-DPA1, HLA-DQB1, HLA-DRA, IL1B, IL6, ITGB3, BAD, BCL2, TLR2, TNF |
hsa05131 | Shigellosis | 10 | 1956, 3553, 3554, 3576, 596, 6500, 7094, 7099, 7124, 7335 | EGFR, IL1B, IL1R1, CXCL8, BCL2, SKP1, TLN1, TLR4, TNF, UBE2V1 |
hsa05146 | Amoebiasis | 10 | 2335, 3553, 3554, 3569, 3576, 4843, 7097, 7099, 7124, 7850 | FN1, IL1B, IL1R1, IL6, CXCL8, NOS2, TLR2, TLR4, TNF, IL1R2 |
hsa05167 | Kaposi sarcoma-associated herpesvirus infection | 10 | 1499, 1827, 2786, 285, 3569, 3572, 3576, 5743, 6774, 7422 | CTNNB1, RCAN1, GNG4, ANGPT2, IL6, IL6ST, CXCL8, PTGS2, STAT3, VEGFA |
hsa05014 | Amyotrophic lateral sclerosis | 10 | 1767, 2876, 4514, 4843, 572, 596, 6647, 7124, 847, 9001 | DNAH5, GPX1, COX3, NOS2, BAD, BCL2, SOD1, TNF, CAT, HAP1 |
hsa01521 | EGFR tyrosine kinase inhibitor resistance | 9 | 1956, 3569, 3570, 3791, 572, 596, 6774, 7422, 80310 | EGFR, IL6, IL6R, KDR, BAD, BCL2, STAT3, VEGFA, PDGFD |
hsa05321 | Inflammatory bowel disease | 9 | 3113, 3119, 3122, 3553, 3569, 6774, 7097, 7099, 7124 | HLA-DPA1, HLA-DQB1, HLA-DRA, IL1B, IL6, STAT3, TLR2, TLR4, TNF |
hsa05160 | Hepatitis C | 9 | 1499, 1956, 3434, 3627, 572, 6256, 6774, 7124, 91543 | CTNNB1, EGFR, IFIT1, CXCL10, BAD, RXRA, STAT3, TNF, RSAD2 |
hsa05140 | Leishmaniasis | 9 | 3113, 3119, 3122, 3553, 4843, 5743, 7097, 7099, 7124 | HLA-DPA1, HLA-DQB1, HLA-DRA, IL1B, NOS2, PTGS2, TLR2, TLR4, TNF |
hsa04657 | IL-17 signaling pathway | 9 | 3553, 3569, 3576, 3627, 3934, 5743, 6278, 6279, 7124 | IL1B, IL6, CXCL8, CXCL10, LCN2, PTGS2, S100A7, S100A8, TNF |
hsa04928 | Parathyroid hormone synthesis, secretion and action | 9 | 1591, 1594, 1956, 596, 6256, 6257, 6258, 7421, 846 | CYP24A1, CYP27B1, EGFR, BCL2, RXRA, RXRB, RXRG, VDR, CASR |
hsa05144 | Malaria | 9 | 3039, 3040, 3043, 3553, 3569, 3576, 7097, 7099, 7124 | HBA1, HBA2, HBB, IL1B, IL6, CXCL8, TLR2, TLR4, TNF |
hsa04064 | NF-kappa B signaling pathway | 9 | 10673, 3553, 3554, 3576, 5743, 596, 6387, 7099, 7124 | TNFSF13B, IL1B, IL1R1, CXCL8, PTGS2, BCL2, CXCL12, TLR4, TNF |
hsa04020 | Calcium signaling pathway | 9 | 185, 1956, 2321, 3357, 3791, 4843, 7422, 80310, 8877 | AGTR1, EGFR, FLT1, HTR2B, KDR, NOS2, VEGFA, PDGFD, SPHK1 |
hsa04933 | AGE-RAGE signaling pathway in diabetic complications | 9 | 185, 2335, 3553, 3569, 3576, 596, 6774, 7124, 7422 | AGTR1, FN1, IL1B, IL6, CXCL8, BCL2, STAT3, TNF, VEGFA |
hsa04550 | Signaling pathways regulating pluripotency of stem cells | 9 | 1499, 3572, 3624, 3625, 3976, 3977, 6774, 92, 93 | CTNNB1, IL6ST, INHBA, INHBB, LIF, LIFR, STAT3, ACVR2A, ACVR2B |
hsa04919 | Thyroid hormone signaling pathway | 8 | 1499, 1827, 3690, 486, 572, 6256, 6257, 6258 | CTNNB1, RCAN1, ITGB3, FXYD2, BAD, RXRA, RXRB, RXRG |
hsa04620 | Toll-like receptor signaling pathway | 8 | 3553, 3569, 3576, 3627, 4283, 7097, 7099, 7124 | IL1B, IL6, CXCL8, CXCL10, CXCL9, TLR2, TLR4, TNF |
hsa05161 | Hepatitis B | 8 | 3569, 3576, 572, 596, 6774, 7097, 7099, 7124 | IL6, CXCL8, BAD, BCL2, STAT3, TLR2, TLR4, TNF |
hsa05010 | Alzheimer disease | 8 | 1499, 3553, 3569, 4514, 4843, 572, 5743, 7124 | CTNNB1, IL1B, IL6, COX3, NOS2, BAD, PTGS2, TNF |
hsa04621 | NOD-like receptor signaling pathway | 8 | 2635, 3553, 3569, 3576, 596, 7099, 7124, 846 | GBP3, IL1B, IL6, CXCL8, BCL2, TLR4, TNF, CASR |
hsa04024 | cAMP signaling pathway | 8 | 1081, 1394, 2550, 2892, 486, 572, 627, 6750 | CGA, CRHR1, GABBR1, GRIA3, FXYD2, BAD, BDNF, SST |
hsa05208 | Chemical carcinogenesis | 8 | 1956, 4257, 4514, 52, 572, 6647, 7422, 847 | EGFR, MGST1, COX3, ACP1, BAD, SOD1, VEGFA, CAT |
hsa04810 | Regulation of actin cytoskeleton | 8 | 1956, 2335, 28984, 3680, 3690, 3694, 6387, 80310 | EGFR, FN1, RGCC, ITGA9, ITGB3, ITGB6, CXCL12, PDGFD |
hsa04932 | Non-alcoholic fatty liver disease | 7 | 3553, 3569, 3570, 3576, 4514, 6256, 7124 | IL1B, IL6, IL6R, CXCL8, COX3, RXRA, TNF |
hsa05130 | Pathogenic Escherichia coli infection | 7 | 3553, 3554, 3569, 3576, 7099, 7124, 8743 | IL1B, IL1R1, IL6, CXCL8, TLR4, TNF, TNFSF10 |
hsa05142 | Chagas disease | 7 | 3553, 3569, 3576, 4843, 7097, 7099, 7124 | IL1B, IL6, CXCL8, NOS2, TLR2, TLR4, TNF |
hsa05016 | Huntington disease | 7 | 1767, 2876, 2892, 4514, 627, 6647, 9001 | DNAH5, GPX1, GRIA3, COX3, BDNF, SOD1, HAP1 |
hsa05410 | Hypertrophic cardiomyopathy | 7 | 3569, 3680, 3690, 3694, 7124, 7168, 7171 | IL6, ITGA9, ITGB3, ITGB6, TNF, TPM1, TPM4 |
hsa04068 | FoxO signaling pathway | 7 | 1901, 1956, 3569, 3575, 6774, 847, 8743 | S1PR1, EGFR, IL6, IL7R, STAT3, CAT, TNFSF10 |
hsa05135 | Yersinia infection | 7 | 2335, 2533, 3553, 3569, 3576, 7099, 7124 | FN1, FYB1, IL1B, IL6, CXCL8, TLR4, TNF |
hsa05162 | Measles | 7 | 3553, 3569, 572, 596, 6774, 7097, 7099 | IL1B, IL6, BAD, BCL2, STAT3, TLR2, TLR4 |
hsa05226 | Gastric cancer | 7 | 1499, 1956, 596, 6256, 6257, 6258, 999 | CTNNB1, EGFR, BCL2, RXRA, RXRB, RXRG, CDH1 |
hsa05170 | Human immunodeficiency virus 1 infection | 7 | 2786, 572, 596, 6500, 7097, 7099, 7124 | GNG4, BAD, BCL2, SKP1, TLR2, TLR4, TNF |
hsa05222 | Small cell lung cancer | 7 | 2335, 4843, 5743, 596, 6256, 6257, 6258 | FN1, NOS2, PTGS2, BCL2, RXRA, RXRB, RXRG |
hsa04936 | Alcoholic liver disease | 6 | 1499, 3553, 3569, 3576, 7099, 7124 | CTNNB1, IL1B, IL6, CXCL8, TLR4, TNF |
hsa05020 | Prion disease | 6 | 3553, 3569, 4514, 572, 6647, 7124 | IL1B, IL6, COX3, BAD, SOD1, TNF |
hsa05133 | Pertussis | 6 | 3553, 3569, 3576, 4843, 7099, 7124 | IL1B, IL6, CXCL8, NOS2, TLR4, TNF |
hsa04672 | Intestinal immune network for IgA production | 6 | 10673, 3113, 3119, 3122, 3569, 6387 | TNFSF13B, HLA-DPA1, HLA-DQB1, HLA-DRA, IL6, CXCL12 |
hsa05332 | Graft-versus-host disease | 6 | 3113, 3119, 3122, 3553, 3569, 7124 | HLA-DPA1, HLA-DQB1, HLA-DRA, IL1B, IL6, TNF |
hsa05414 | Dilated cardiomyopathy | 6 | 3680, 3690, 3694, 7124, 7168, 7171 | ITGA9, ITGB3, ITGB6, TNF, TPM1, TPM4 |
hsa04072 | Phospholipase D signaling pathway | 6 | 185, 1956, 3576, 3577, 80310, 8877 | AGTR1, EGFR, CXCL8, CXCR1, PDGFD, SPHK1 |
hsa05134 | Legionellosis | 6 | 3553, 3569, 3576, 7097, 7099, 7124 | IL1B, IL6, CXCL8, TLR2, TLR4, TNF |
hsa04668 | TNF signaling pathway | 6 | 3553, 3569, 3627, 3976, 5743, 7124 | IL1B, IL6, CXCL10, LIF, PTGS2, TNF |
hsa04145 | Phagosome | 6 | 3113, 3119, 3122, 3690, 7097, 7099 | HLA-DPA1, HLA-DQB1, HLA-DRA, ITGB3, TLR2, TLR4 |
hsa04723 | Retrograde endocannabinoid signaling | 6 | 1268, 2166, 2555, 2786, 2892, 5743 | CNR1, FAAH, GABRA2, GNG4, GRIA3, PTGS2 |
hsa04514 | Cell adhesion molecules | 6 | 3113, 3119, 3122, 3680, 5789, 999 | HLA-DPA1, HLA-DQB1, HLA-DRA, ITGA9, PTPRD, CDH1 |
hsa05143 | African trypanosomiasis | 6 | 3039, 3040, 3043, 3553, 3569, 7124 | HBA1, HBA2, HBB, IL1B, IL6, TNF |
hsa05215 | Prostate cancer | 6 | 1499, 1956, 572, 596, 7850, 80310 | CTNNB1, EGFR, BAD, BCL2, IL1R2, PDGFD |
hsa04940 | Type I diabetes mellitus | 6 | 2572, 3113, 3119, 3122, 3553, 7124 | GAD2, HLA-DPA1, HLA-DQB1, HLA-DRA, IL1B, TNF |
hsa04217 | Necroptosis | 6 | 3553, 596, 6774, 7099, 7124, 8743 | IL1B, BCL2, STAT3, TLR4, TNF, TNFSF10 |
hsa05150 | Staphylococcus aureus infection | 6 | 1672, 3075, 3113, 3119, 3122, 5340 | DEFB1, CFH, HLA-DPA1, HLA-DQB1, HLA-DRA, PLG |
hsa05223 | Non-small cell lung cancer | 6 | 1956, 572, 6256, 6257, 6258, 6774 | EGFR, BAD, RXRA, RXRB, RXRG, STAT3 |
hsa05216 | Thyroid cancer | 5 | 1499, 6256, 6257, 6258, 999 | CTNNB1, RXRA, RXRB, RXRG, CDH1 |
hsa04310 | Wnt signaling pathway | 5 | 1499, 4316, 6500, 84870, 8840 | CTNNB1, MMP7, SKP1, RSPO3, CCN4 |
hsa04261 | Adrenergic signaling in cardiomyocytes | 5 | 185, 486, 596, 7168, 7171 | AGTR1, FXYD2, BCL2, TPM1, TPM4 |
hsa04727 | GABAergic synapse | 5 | 2550, 2555, 2572, 2786, 9001 | GABBR1, GABRA2, GAD2, GNG4, HAP1 |
hsa04371 | Apelin signaling pathway | 5 | 185, 2786, 4843, 8877, 999 | AGTR1, GNG4, NOS2, SPHK1, CDH1 |
hsa04920 | Adipocytokine signaling pathway | 5 | 6256, 6257, 6258, 6774, 7124 | RXRA, RXRB, RXRG, STAT3, TNF |
hsa04931 | Insulin resistance | 5 | 3569, 5507, 5524, 6774, 7124 | IL6, PPP1R3C, PTPA, STAT3, TNF |
hsa04934 | Cushing syndrome | 5 | 1394, 1499, 185, 1956, 51655 | CRHR1, CTNNB1, AGTR1, EGFR, RASD1 |
hsa04935 | Growth hormone synthesis, secretion and action | 5 | 1442, 1443, 3486, 6750, 6774 | CSH1, CSH2, IGFBP3, SST, STAT3 |
hsa05310 | Asthma | 5 | 3113, 3119, 3122, 5553, 7124 | HLA-DPA1, HLA-DQB1, HLA-DRA, PRG2, TNF |
hsa04370 | VEGF signaling pathway | 5 | 3791, 572, 5743, 7422, 8877 | KDR, BAD, PTGS2, VEGFA, SPHK1 |
hsa04713 | Circadian entrainment | 4 | 2786, 2892, 51655, 8863 | GNG4, GRIA3, RASD1, PER3 |
hsa04750 | Inflammatory mediator regulation of TRP channels | 4 | 3357, 3553, 3554, 59341 | HTR2B, IL1B, IL1R1, TRPV4 |
hsa04022 | cGMP-PKG signaling pathway | 4 | 185, 486, 572, 5997 | AGTR1, FXYD2, BAD, RGS2 |
hsa05219 | Bladder cancer | 4 | 1956, 3576, 7422, 999 | EGFR, CXCL8, VEGFA, CDH1 |
hsa05218 | Melanoma | 4 | 1956, 572, 80310, 999 | EGFR, BAD, PDGFD, CDH1 |
hsa05225 | Hepatocellular carcinoma | 4 | 1499, 1956, 4257, 572 | CTNNB1, EGFR, MGST1, BAD |
hsa05212 | Pancreatic cancer | 4 | 1956, 572, 6774, 7422 | EGFR, BAD, STAT3, VEGFA |
hsa04926 | Relaxin signaling pathway | 4 | 1956, 2786, 4843, 7422 | EGFR, GNG4, NOS2, VEGFA |
hsa05322 | Systemic lupus erythematosus | 4 | 3113, 3119, 3122, 7124 | HLA-DPA1, HLA-DQB1, HLA-DRA, TNF |
hsa04520 | Adherens junction | 4 | 1499, 1956, 52, 999 | CTNNB1, EGFR, ACP1, CDH1 |
hsa05412 | Arrhythmogenic right ventricular cardiomyopathy | 4 | 1499, 3680, 3690, 3694 | CTNNB1, ITGA9, ITGB3, ITGB6 |
hsa05330 | Allograft rejection | 4 | 3113, 3119, 3122, 7124 | HLA-DPA1, HLA-DQB1, HLA-DRA, TNF |
hsa04071 | Sphingolipid signaling pathway | 4 | 1901, 596, 7124, 8877 | S1PR1, BCL2, TNF, SPHK1 |
hsa04915 | Estrogen signaling pathway | 4 | 1956, 2550, 5241, 596 | EGFR, GABBR1, PGR, BCL2 |
hsa04612 | Antigen processing and presentation | 4 | 3113, 3119, 3122, 7124 | HLA-DPA1, HLA-DQB1, HLA-DRA, TNF |
hsa05203 | Viral carcinogenesis | 4 | 3572, 572, 6774, 991 | IL6ST, BAD, STAT3, CDC20 |
hsa04921 | Oxytocin signaling pathway | 4 | 1827, 1956, 5743, 5997 | RCAN1, EGFR, PTGS2, RGS2 |
hsa05204 | Chemical carcinogenesis | 4 | 1577, 4257, 54658, 5743 | CYP3A5, MGST1, UGT1A1, PTGS2 |
hsa04270 | Vascular smooth muscle contraction | 4 | 10203, 10267, 133, 185 | CALCRL, RAMP1, ADM, AGTR1 |
hsa05235 | PD-L1 expression and PD-1 checkpoint pathway in cancer | 4 | 1956, 6774, 7097, 7099 | EGFR, STAT3, TLR2, TLR4 |
hsa05213 | Endometrial cancer | 4 | 1499, 1956, 572, 999 | CTNNB1, EGFR, BAD, CDH1 |
hsa04210 | Apoptosis | 4 | 572, 596, 7124, 8743 | BAD, BCL2, TNF, TNFSF10 |
hsa04380 | Osteoclast differentiation | 4 | 3553, 3554, 3690, 7124 | IL1B, IL1R1, ITGB3, TNF |
hsa04625 | C-type lectin receptor signaling pathway | 4 | 3553, 3569, 5743, 7124 | IL1B, IL6, PTGS2, TNF |
hsa04512 | ECM-receptor interaction | 4 | 2335, 3680, 3690, 3694 | FN1, ITGA9, ITGB3, ITGB6 |
hsa05320 | Autoimmune thyroid disease | 4 | 1081, 3113, 3119, 3122 | CGA, HLA-DPA1, HLA-DQB1, HLA-DRA |
hsa04218 | Cellular senescence | 4 | 3486, 3569, 3576, 59341 | IGFBP3, IL6, CXCL8, TRPV4 |
hsa04976 | Bile secretion | 4 | 486, 54658, 6256, 760 | FXYD2, UGT1A1, RXRA, CA2 |
hsa04610 | Complement and coagulation cascades | 4 | 2, 2160, 3075, 5340 | A2M, F11, CFH, PLG |
hsa01524 | Platinum drug resistance | 4 | 4257, 538, 572, 596 | MGST1, ATP7A, BAD, BCL2 |
hsa04978 | Mineral absorption | 4 | 4499, 486, 538, 7421 | MT1M, FXYD2, ATP7A, VDR |
hsa05224 | Breast cancer | 4 | 1499, 1956, 3280, 5241 | CTNNB1, EGFR, HES1, PGR |
hsa05210 | Colorectal cancer | 4 | 1499, 1956, 572, 596 | CTNNB1, EGFR, BAD, BCL2 |
hsa03320 | PPAR signaling pathway | 4 | 2167, 6256, 6257, 6258 | FABP4, RXRA, RXRB, RXRG |
hsa04260 | Cardiac muscle contraction | 4 | 4514, 486, 7168, 7171 | COX3, FXYD2, TPM1, TPM4 |
hsa01240 | Biosynthesis of cofactors | 4 | 210, 29968, 54658, 8942 | ALAD, PSAT1, UGT1A1, KYNU |
hsa01200 | Carbon metabolism | 3 | 29968, 5723, 847 | PSAT1, PSPH, CAT |
hsa04929 | GnRH secretion | 3 | 1081, 2550, 3814 | CGA, GABBR1, KISS1 |
hsa01522 | Endocrine resistance | 3 | 1956, 572, 596 | EGFR, BAD, BCL2 |
hsa05012 | Parkinson disease | 3 | 11315, 4514, 6647 | PARK7, COX3, SOD1 |
hsa05415 | Diabetic cardiomyopathy | 3 | 185, 4514, 5524 | AGTR1, COX3, PTPA |
hsa04972 | Pancreatic secretion | 3 | 1359, 486, 760 | CPA3, FXYD2, CA2 |
hsa04917 | Prolactin signaling pathway | 3 | 1081, 5617, 6774 | CGA, PRL, STAT3 |
hsa00982 | Drug metabolism | 3 | 1577, 4257, 54658 | CYP3A5, MGST1, UGT1A1 |
hsa05100 | Bacterial invasion of epithelial cells | 3 | 1499, 2335, 999 | CTNNB1, FN1, CDH1 |
hsa05416 | Viral myocarditis | 3 | 3113, 3119, 3122 | HLA-DPA1, HLA-DQB1, HLA-DRA |
hsa04540 | Gap junction | 3 | 1956, 3357, 80310 | EGFR, HTR2B, PDGFD |
hsa04614 | Renin-angiotensin system | 3 | 1359, 185, 4012 | CPA3, AGTR1, LNPEP |
hsa04120 | Ubiquitin mediated proteolysis | 3 | 6500, 7428, 991 | SKP1, VHL, CDC20 |
hsa04613 | Neutrophil extracellular trap formation | 3 | 3690, 7097, 7099 | ITGB3, TLR2, TLR4 |
hsa04146 | Peroxisome | 3 | 4843, 6647, 847 | NOS2, SOD1, CAT |
hsa04918 | Thyroid hormone synthesis | 3 | 1081, 2876, 486 | CGA, GPX1, FXYD2 |
hsa04114 | Oocyte meiosis | 3 | 5241, 6500, 991 | PGR, SKP1, CDC20 |
hsa04923 | Regulation of lipolysis in adipocytes | 3 | 1081, 2167, 5743 | CGA, FABP4, PTGS2 |
hsa00480 | Glutathione metabolism | 3 | 2876, 4257, 9588 | GPX1, MGST1, PRDX6 |
hsa04623 | Cytosolic DNA-sensing pathway | 3 | 3553, 3569, 3627 | IL1B, IL6, CXCL10 |
hsa05120 | Epithelial cell signaling in Helicobacter pylori infection | 3 | 1956, 3576, 3577 | EGFR, CXCL8, CXCR1 |
hsa04722 | Neurotrophin signaling pathway | 3 | 572, 596, 627 | BAD, BCL2, BDNF |
hsa04144 | Endocytosis | 3 | 1956, 3577, 9230 | EGFR, CXCR1, RAB11B |
hsa04622 | RIG-I-like receptor signaling pathway | 3 | 3576, 3627, 7124 | CXCL8, CXCL10, TNF |
hsa04971 | Gastric acid secretion | 3 | 2520, 6750, 760 | GAST, SST, CA2 |
hsa05032 | Morphine addiction | 3 | 2550, 2555, 2786 | GABBR1, GABRA2, GNG4 |
hsa01523 | Antifolate resistance | 3 | 3553, 3569, 7124 | IL1B, IL6, TNF |
hsa04658 | Th1 and Th2 cell differentiation | 3 | 3113, 3119, 3122 | HLA-DPA1, HLA-DQB1, HLA-DRA |
hsa00980 | Metabolism of xenobiotics by cytochrome P450 | 3 | 1577, 4257, 54658 | CYP3A5, MGST1, UGT1A1 |
hsa00140 | Steroid hormone biosynthesis | 3 | 1577, 3291, 54658 | CYP3A5, HSD11B2, UGT1A1 |
hsa05211 | Renal cell carcinoma | 3 | 572, 7422, 7428 | BAD, VEGFA, VHL |
hsa04726 | Serotonergic synapse | 3 | 2786, 3357, 5743 | GNG4, HTR2B, PTGS2 |
hsa04330 | Notch signaling pathway | 2 | 23220, 3280 | DTX4, HES1 |
hsa04390 | Hippo signaling pathway | 2 | 1499, 999 | CTNNB1, CDH1 |
hsa04141 | Protein processing in endoplasmic reticulum | 2 | 596, 6500 | BCL2, SKP1 |
hsa00380 | Tryptophan metabolism | 2 | 847, 8942 | CAT, KYNU |
hsa04140 | Autophagy | 2 | 572, 596 | BAD, BCL2 |
hsa04742 | Taste transduction | 2 | 2550, 2555 | GABBR1, GABRA2 |
hsa00601 | Glycosphingolipid biosynthesis | 2 | 10402, 6487 | ST3GAL6, ST3GAL3 |
hsa04910 | Insulin signaling pathway | 2 | 5507, 572 | PPP1R3C, BAD |
hsa04913 | Ovarian steroidogenesis | 2 | 1081, 5743 | CGA, PTGS2 |
hsa04730 | Long-term depression | 2 | 1394, 2892 | CRHR1, GRIA3 |
hsa04360 | Axon guidance | 2 | 59277, 6387 | NTN4, CXCL12 |
hsa04670 | Leukocyte transendothelial migration | 2 | 1499, 6387 | CTNNB1, CXCL12 |
hsa05231 | Choline metabolism in cancer | 2 | 1956, 80310 | EGFR, PDGFD |
hsa04710 | Circadian rhythm | 2 | 6500, 8863 | SKP1, PER3 |
hsa00100 | Steroid biosynthesis | 2 | 1591, 1594 | CYP24A1, CYP27B1 |
hsa05221 | Acute myeloid leukemia | 2 | 572, 6774 | BAD, STAT3 |
hsa00830 | Retinol metabolism | 2 | 1577, 54658 | CYP3A5, UGT1A1 |
hsa04960 | Aldosterone-regulated sodium reabsorption | 2 | 3291, 486 | HSD11B2, FXYD2 |
hsa04912 | GnRH signaling pathway | 2 | 1081, 1956 | CGA, EGFR |
hsa04012 | ErbB signaling pathway | 2 | 1956, 572 | EGFR, BAD |
hsa04110 | Cell cycle | 2 | 6500, 991 | SKP1, CDC20 |
hsa00860 | Porphyrin metabolism | 2 | 210, 54658 | ALAD, UGT1A1 |
hsa04650 | Natural killer cell mediated cytotoxicity | 2 | 7124, 8743 | TNF, TNFSF10 |
hsa04964 | Proximal tubule bicarbonate reclamation | 2 | 486, 760 | FXYD2, CA2 |
hsa04724 | Glutamatergic synapse | 2 | 2786, 2892 | GNG4, GRIA3 |
hsa05033 | Nicotine addiction | 2 | 2555, 2892 | GABRA2, GRIA3 |
hsa05034 | Alcoholism | 2 | 2786, 627 | GNG4, BDNF |
hsa00514 | Other types of O-glycan biosynthesis | 2 | 6480, 6487 | ST6GAL1, ST3GAL3 |
hsa04974 | Protein digestion and absorption | 2 | 1359, 486 | CPA3, FXYD2 |
hsa04961 | Endocrine and other factor-regulated calcium reabsorption | 2 | 486, 7421 | FXYD2, VDR |
hsa01230 | Biosynthesis of amino acids | 2 | 29968, 5723 | PSAT1, PSPH |
hsa04213 | Longevity regulating pathway | 2 | 6647, 847 | SOD1, CAT |
hsa04611 | Platelet activation | 2 | 3690, 7094 | ITGB3, TLN1 |
hsa04725 | Cholinergic synapse | 2 | 2786, 596 | GNG4, BCL2 |
hsa00983 | Drug metabolism | 2 | 4257, 54658 | MGST1, UGT1A1 |
hsa00330 | Arginine and proline metabolism | 2 | 1158, 4843 | CKM, NOS2 |
hsa00260 | Glycine, serine and threonine metabolism | 2 | 29968, 5723 | PSAT1, PSPH |
hsa04714 | Thermogenesis | 2 | 1268, 4514 | CNR1, COX3 |
hsa04966 | Collecting duct acid secretion | 2 | 6521, 760 | SLC4A1, CA2 |
hsa04115 | p53 signaling pathway | 2 | 3486, 596 | IGFBP3, BCL2 |
hsa00590 | Arachidonic acid metabolism | 2 | 10728, 5743 | PTGES3, PTGS2 |
hsa04728 | Dopaminergic synapse | 2 | 2786, 2892 | GNG4, GRIA3 |
hsa00740 | Riboflavin metabolism | 1 | 52 | ACP1 |
hsa00515 | Mannose type O-glycan biosynthesis | 1 | 6487 | ST3GAL3 |
hsa04950 | Maturity onset diabetes of the young | 1 | 3280 | HES1 |
hsa00040 | Pentose and glucuronate interconversions | 1 | 54658 | UGT1A1 |
hsa00920 | Sulfur metabolism | 1 | 8991 | SELENBP1 |
hsa00534 | Glycosaminoglycan biosynthesis | 1 | 90161 | HS6ST2 |
hsa04150 | mTOR signaling pathway | 1 | 7124 | TNF |
hsa05017 | Spinocerebellar ataxia | 1 | 2892 | GRIA3 |
hsa00910 | Nitrogen metabolism | 1 | 760 | CA2 |
hsa04142 | Lysosome | 1 | 27074 | LAMP3 |
hsa02010 | ABC transporters | 1 | 1672 | DEFB1 |
hsa03266 | Virion | 1 | 3690 | ITGB3 |
hsa00630 | Glyoxylate and dicarboxylate metabolism | 1 | 847 | CAT |
hsa04211 | Longevity regulating pathway | 1 | 847 | CAT |
hsa00220 | Arginine biosynthesis | 1 | 4843 | NOS2 |
hsa05031 | Amphetamine addiction | 1 | 2892 | GRIA3 |
hsa00513 | Various types of N-glycan biosynthesis | 1 | 6487 | ST3GAL3 |
hsa00750 | Vitamin B6 metabolism | 1 | 29968 | PSAT1 |
hsa05220 | Chronic myeloid leukemia | 1 | 572 | BAD |
hsa05340 | Primary immunodeficiency | 1 | 3575 | IL7R |
hsa04216 | Ferroptosis | 1 | 23657 | SLC7A11 |
hsa03460 | Fanconi anemia pathway | 1 | 3280 | HES1 |
hsa05030 | Cocaine addiction | 1 | 627 | BDNF |
hsa00563 | Glycosylphosphatidylinositol (GPI)-anchor biosynthesis | 1 | 5281 | PIGF |
hsa04916 | Melanogenesis | 1 | 1499 | CTNNB1 |
hsa00053 | Ascorbate and aldarate metabolism | 1 | 54658 | UGT1A1 |
hsa04660 | T cell receptor signaling pathway | 1 | 7124 | TNF |
hsa04152 | AMPK signaling pathway | 1 | 9230 | RAB11B |
hsa05217 | Basal cell carcinoma | 1 | 1499 | CTNNB1 |
hsa04970 | Salivary secretion | 1 | 486 | FXYD2 |
hsa05214 | Glioma | 1 | 1956 | EGFR |
hsa00510 | N-Glycan biosynthesis | 1 | 6480 | ST6GAL1 |
hsa00270 | Cysteine and methionine metabolism | 1 | 29968 | PSAT1 |
hsa04925 | Aldosterone synthesis and secretion | 1 | 185 | AGTR1 |
hsa04340 | Hedgehog signaling pathway | 1 | 596 | BCL2 |
hsa04911 | Insulin secretion | 1 | 486 | FXYD2 |
hsa00250 | Alanine, aspartate and glutamate metabolism | 1 | 2572 | GAD2 |
hsa04962 | Vasopressin-regulated water reabsorption | 1 | 9230 | RAB11B |
hsa04664 | Fc epsilon RI signaling pathway | 1 | 7124 | TNF |
hsa04973 | Carbohydrate digestion and absorption | 1 | 486 | FXYD2 |
hsa00430 | Taurine and hypotaurine metabolism | 1 | 2572 | GAD2 |
hsa04215 | Apoptosis | 1 | 596 | BCL2 |
hsa04924 | Renin secretion | 1 | 185 | AGTR1 |
hsa04927 | Cortisol synthesis and secretion | 1 | 185 | AGTR1 |
hsa04137 | Mitophagy | 1 | 10370 | CITED2 |
hsa00410 | beta-Alanine metabolism | 1 | 2572 | GAD2 |
hsa00650 | Butanoate metabolism | 1 | 2572 | GAD2 |
hsa00052 | Galactose metabolism | 1 | 3906 | LALBA |
hsa00600 | Sphingolipid metabolism | 1 | 8877 | SPHK1 |
hsa00190 | Oxidative phosphorylation | 1 | 4514 | COX3 |
hsa05230 | Central carbon metabolism in cancer | 1 | 1956 | EGFR |
hsa00533 | Glycosaminoglycan biosynthesis | 1 | 6487 | ST3GAL3 |
hsa00532 | Glycosaminoglycan biosynthesis | 1 | 55790 | CSGALNACT1 |
hsa04914 | Progesterone-mediated oocyte maturation | 1 | 5241 | PGR |
hsa04979 | Cholesterol metabolism | 1 | 4018 | LPA |
hsa00730 | Thiamine metabolism | 1 | 52 | ACP1 |
hsa04740 | Olfactory transduction | 1 | 5997 | RGS2 |
hsa04666 | Fc gamma R-mediated phagocytosis | 1 | 8877 | SPHK1 |
hsa04930 | Type II diabetes mellitus | 1 | 7124 | TNF |
hsa00604 | Glycosphingolipid biosynthesis | 1 | 8869 | ST3GAL5 |
EPEK is a comprehensive knowledgebase of expression data relevant to ectopic pregnancy in humans that has been collated and curated from the published scientific literature. We are not liable for any inaccuracies or omissions of any expression data or published scientific literature pertaining to ectopic pregnancy, and users are recommended to use their own discretion while utilizing our resource. The primary goal of developing this resource is to facilitate basic research on ectopic pregnancy in humans, and it does not necessarily reflect the views or objectives of our employers or funders.